| EC |
4.2.3.212 |
| Accepted name: |
(+)-δ-cadinol synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate + H2O = (+)-δ-cadinol + diphosphate |
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For diagram of ent-cadinane sesquiterpenoid biosynthesis, click here |
| Glossary: |
(+)-δ-cadinol = (1S,4R,4aS,8aR)-1,6-dimethyl-4-(propan-2-yl)-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-ol = (+)-torreyol |
| Other name(s): |
δ-cadinol synthase (ambiguous) |
| Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-δ-cadinol-forming] |
| Comments: |
The enzyme is involved in the biosynthesis of sesquiterpenoids from (2E,6E)-farnesyl diphosphate in fungi such as Boreostereum vibrans and Coniophora puteana. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Zhou, H., Yang, Y.L., Zeng, J., Zhang, L., Ding, Z.H. and Zeng, Y. Identification and characterization of a δ-cadinol synthase potentially involved in the formation of boreovibrins in Boreostereum vibrans of basidiomycota. Nat. Prod. Bioprospect. 6 (2016) 167–171. [DOI] [PMID: 27038475] |
| 2. |
Ringel, M., Dimos, N., Himpich, S., Haack, M., Huber, C., Eisenreich, W., Schenk, G., Loll, B. and Bruck, T. Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol. Microb. Cell Fact. 21:64 (2022). [DOI] [PMID: 35440053] |
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| [EC 4.2.3.212 created 2023] |
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