| EC |
4.2.3.218 |
| Accepted name: |
variediene synthase |
| Reaction: |
geranylgeranyl diphosphate = variediene + diphosphate |
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For diagram of miscellaneous diterpenoid biosynthesis, click here |
| Glossary: |
variediene = (3aR,3bS,6E,10Z,11aR)-3,3,6,10,11a-pentamethyl-2,3,3a,3b,4,5,8,9,11,11a-decahydro-1H-cyclonona[a]pentalene |
| Other name(s): |
EvVS |
| Systematic name: |
geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, variediene-forming) |
| Comments: |
A diterpenoid synthase enzyme isolated from the fungus Aspergillus stellatus. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Qin, B., Matsuda, Y., Mori, T., Okada, M., Quan, Z., Mitsuhashi, T., Wakimoto, T. and Abe, I. An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping. Angew. Chem. Int. Ed. Engl. 55 (2016) 1658–1661. [DOI] [PMID: 26546087] |
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| [EC 4.2.3.218 created 2023] |
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