| EC |
4.2.1.84 |
| Accepted name: |
nitrile hydratase |
| Reaction: |
an aliphatic amide = a nitrile + H2O |
| Other name(s): |
nitrilase (ambiguous); 3-cyanopyridine hydratase; NHase; L-NHase; H-NHase; acrylonitrile hydratase; aliphatic nitrile hydratase; nitrile hydro-lyase |
| Systematic name: |
aliphatic-amide hydro-lyase (nitrile-forming) |
| Comments: |
Acts on short-chain aliphatic nitriles, converting them into the corresponding amides. Does not act on these amides or on aromatic nitriles. cf. EC 3.5.5.1 nitrilase. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 82391-37-5 |
| References: |
| 1. |
Asano, Y., Fujishiro, K., Tani, Y. and Yamada, H. Microbial degradation of nitrile compounds. 5. Aliphatic nitrile hydratase from Arthrobacter sp J-1. Purification and characterization. Agric. Biol. Chem. 46 (1982) 1165–1174. |
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| [EC 4.2.1.84 created 1989] |
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