|
Your query returned 2 entries. Printable version
EC | 4.2.1.79 | ||||
Accepted name: | 2-methylcitrate dehydratase | ||||
Reaction: | (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O | ||||
Glossary: | (2S,3S)-2-methylcitrate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate cis-2-methylaconitate = (Z)-but-2-ene-1,2,3-tricarboxylate |
||||
Other name(s): | 2-methylcitrate hydro-lyase; PrpD; 2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase | ||||
Systematic name: | (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming] | ||||
Comments: | The enzyme is specific for (2S,3S)-methylcitrate, showing no activity with (2R,3S)-methylcitrate [2]. The enzyme can also use cis-aconitate as a substrate but more slowly [2]. Both this enzyme and EC 4.2.1.3, aconitate hydratase, are required to complete the isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate [2]. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 80891-26-5 | ||||
References: |
| ||||
EC | 4.2.1.99 | ||||
Accepted name: | 2-methylisocitrate dehydratase | ||||
Reaction: | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O | ||||
Glossary: | cis-2-methylaconitate = (Z)-but-2-ene-1,2,3-tricarboxylate (2S,3R)-2-methylisocitrate = (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = threo-Ds-2-methylisocitrate |
||||
Other name(s): | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase | ||||
Systematic name: | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming] | ||||
Comments: | The enzyme from the fungus Yarrowia lipolytica (Saccharomycopsis) does not act on isocitrate. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 170780-51-5 | ||||
References: |
| ||||