| EC |
4.2.3.216 |
| Accepted name: |
somaliensene A synthase |
| Reaction: |
geranylfarnesyl diphosphate = somaliensene A + diphosphate |
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For diagram of somaliensene A and B biosynthesis, click here |
| Glossary: |
somaliensene A = (1S,5R,6R)-6-methyl-6-[(3E,7E,11E)-trimethyltrideca-3,7,11-trien-1-yl]bicyclo[3.1.1]hept-2-ene |
| Other name(s): |
stsC (gene name) |
| Systematic name: |
geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, somaliensene A-forming) |
| Comments: |
A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis. The enzyme also produces somalensene B (cf. EC 4.2.3.217, somaliensene B synthase). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Yang, Y., Zhang, Y., Zhang, S., Chen, Q., Ma, K., Bao, L., Tao, Y., Yin, W., Wang, G. and Liu, H. Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 81 (2018) 1089–1092. [DOI] [PMID: 29553734] |
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| [EC 4.2.3.216 created 2023] |
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