The Enzyme Database

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EC 4.2.3.217     
Accepted name: somaliensene B synthase
Reaction: geranylfarnesyl diphosphate = (–)-somaliensene B + diphosphate
For diagram of somaliensene A and B biosynthesis, click here
Glossary: (–)-somaliensene B = (4S)-1-methyl-4-[(5E,9E,13E)-6,10,14-trimethylpentadeca-1,5,9,13-tetraen-2-yl]cyclohex-1-ene
Other name(s): stsC (gene name)
Systematic name: geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, (–)-somaliensene B-forming)
Comments: A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis. The enzyme also produces somaliensene A (cf. EC 4.2.3.216, somaliensene A synthase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Yang, Y., Zhang, Y., Zhang, S., Chen, Q., Ma, K., Bao, L., Tao, Y., Yin, W., Wang, G. and Liu, H. Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 81 (2018) 1089–1092. [DOI] [PMID: 29553734]
[EC 4.2.3.217 created 2023]
 
 


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