The Enzyme Database


 

List of Publications

ExplorEnz

ExplorEnz: a MySQL database of the IUBMB enzyme nomenclature. A.G. McDonald, S. Boyce, G.P. Moss, H.B.F. Dixon and K.F. Tipton. BMC Biochem. 27, 8:14 pp. 7 (2007). [PMID: 17662133]

ExplorEnz: the primary source of the IUBMB enzyme list. A.G. McDonald, S. Boyce and K.F. Tipton. Nucleic Acids Res. 37, D593–D597 (2009). [PMID: 18776214]

Enzyme Classification

Fifty-five years of Enzyme classification: advances and difficulties. McDonald, A.G. and Tipton, K.F. FEBS J. 281(2), 583–592 (2014). [PMID: 24103004]

Enzyme Classification and Nomenclature. K.F. Tipton and S. Boyce. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd, Chichester: http://www.els.net doi: 10.1038/npg.els.0003893 (2005).

History of the enzyme nomenclature system. S. Boyce and K.F. Tipton. Bioinformatics 16, 34–40 (2000). [PMID: 10812475]

Enzyme nomenclature: a personal retrospective. E.C. Webb. FASEB J. 7, 1192–1194 (1993). [PMID: 8375619]

The naming of parts. K.F. Tipton. Trends Biochem. Sci. 18, 113–115 (1993). [PMID: 8493719]

Earlier Published Versions of the Enzyme List

M. Dixon and E. C. Webb (1958) Enzymes. Longmans, Green & Co., London, and Academic Press, New York.

M. Dixon and E. C. Webb (1964) Enzymes. 2nd Edition, Longmans, Green & Co., London, and Academic Press, New York.

M. Dixon, E. C. Webb, C.J.R Thorne and K.F. Tipton (1979) Enzymes. 3rd Edition, Longmans, Green & Co., London, and Academic Press, New York.

IUBMB Publications on Enzyme Classification & Nomenclature

Report of the Commission on Enzymes of the International Union of Biochemistry (1961) Pergamon Press, Oxford.

Enzyme Nomenclature. Recommendations (1964) of the International Union of Biochemistry on the Nomenclature and Classification of Enzymes, Together with their Units and the Symbols of Enzyme Kinetics. Elsevier, Amsterdam (1965).

Enzyme Nomenclature. Recommendations (1972) of the Commission on Biochemical Nomenclature on the Nomenclature and Classification of Enzymes, Together with their Units and the Symbols of Enzyme Kinetics. Elsevier, Amsterdam (1973).

Enzyme Nomenclature. Recommendations (1978) of the Nomenclature Committee of the International Union of Biochemistry on the Nomenclature and Classification of Enzymes. Academic Press, New York (1979).

Enzyme Nomenclature (1984). Recommendations of the Nomenclature Committee of the International Union of Biochemistry on the Nomenclature and Classification of Enzymes. Academic Press, New York (1984).

Enzyme Nomenclature (1992). Recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology, Academic Press, San Diego, CA (1984).

The Classification Rules on this website are adapted from those in the 1992 book.

Supplements

Following the 1992 Enzyme nomenclature book the following lists of new enzymes added were published

Supplement 1 (Peptidases, prepared by A.J. Barrett) Eur. J. Biochem. 223, 1–5 (1994).

Supplement 2 (Peptidases, prepared by A.J. Barrett) Eur. J. Biochem. 232, 1–6 (1995).

Supplement 3 (Peptidases, prepared by A.J. Barrett) Eur. J. Biochem. 232, 1–6; Eur. J. Biochem. 237, 1–5 (1996).

Supplement 4 (Peptidases, prepared by A.J. Barrett) Eur. J. Biochem. 250, 1–6 (1997)

Supplement 5 (Update to Enzyme Nomenclature List, prepared by K.F. Tipton and S. Boyce) Eur. J. Biochem. 264, 610–650 (1999).

From 2000–2006 Supplements 6–11 were published on the web: http://www.chem.qmul.ac.uk/iubmb/enzyme/supplements/
ExplorEnz does not produce supplements since the list is now updated on a rolling basis, but quarterly lists of additions are available here

Related works

Elucidation of metabolic pathways from enzyme classification data. McDonald, A.G. and Tipton, K.F. Methods Mol. Biol. 1083, 173–186 (2014). [PMID: 24218216]

Tracing metabolic pathways from enzyme data. A.G. McDonald, K.F. Tipton and S. Boyce. Biochim. Biophys. Acta. 1794, 1364–1371 (2009). [PMID: 19563919]

Eliciting possible reaction equations and metabolic pathways involving orphan metabolites. Kotera, M., McDonald, A.G., Boyce, S. and Tipton, K.F. J. Chem. Inf. Model. 48(12), 2335–2349 (2008). [PMID: 19053521]

Functional group and substructure searching as a tool in metabolomics. Kotera, M., McDonald, A.G., Boyce, S. and Tipton, K.F. PLoS ONE 3(2): e1537 (2008). [PMID: 18253485]

Extending enzyme classification with metabolic and kinetic data: Some difficulties to be resolved. S. Boyce, K.F. Tipton and A.G. McDonald. Proceedings of the 1st International Beilstein Workshop on Experimental Standard Conditions of Enzyme Characterizations. (Edited by M.G. Hicks & C. Kettner) pp. 17–43, Beilstein Institut, Frankfurt, Germany (2004).

From the enzyme list to pathways and back again. A.G. McDonald, K.F. Tipton and S. Boyce. Proceedings of the 3rd International Beilstein Workshop on Experimental Standard Conditions of Enzyme Characterizations. (Edited by M.G. Hicks & C. Kettner) pp. 109–122, Beilstein Institut, Frankfurt, Germany (2008).