The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

[+subclass]. [+sub-subclass]. [+serial] [-all]

EC 1 [+]   
    EC 1.1  [+]      
        EC 1.1.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.1.2       [+]    With a cytochrome as acceptor 
        EC 1.1.3       [+]    With oxygen as acceptor 
        EC 1.1.4       [+]    With a disulfide as acceptor 
        EC 1.1.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.1.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.1.9       [+]    With a copper protein as acceptor 
        EC 1.1.98       [+]    With other, known, physiological acceptors 
        EC 1.1.99       [+]    With unknown physiological acceptors 
    EC 1.2  [+]      
        EC 1.2.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.2.2       [+]    With a cytochrome as acceptor 
        EC 1.2.3       [+]    With oxygen as acceptor 
        EC 1.2.4       [+]    With a disulfide as acceptor 
        EC 1.2.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.2.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.2.98       [+]    With other, known, physiological acceptors 
        EC 1.2.99       [+]    With unknown physiological acceptors 
    EC 1.3  [+]      
        EC 1.3.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.3.2       [+]    With a cytochrome as acceptor 
        EC 1.3.3       [+]    With oxygen as acceptor 
        EC 1.3.4       [+]    With a disulfide as acceptor 
        EC 1.3.5       [+]    With a quinone or related compound as acceptor 
        EC 1.3.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.3.8       [+]    With a flavin as acceptor 
        EC 1.3.98       [+]    With other, known, physiological acceptors 
        EC 1.3.99       [+]    With unknown physiological acceptors 
    EC 1.4  [+]      
        EC 1.4.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.4.2       [+]    With a cytochrome as acceptor 
        EC 1.4.3       [+]    With oxygen as acceptor 
        EC 1.4.4       [+]    With a disulfide as acceptor 
        EC 1.4.5       [+]    With a quinone or other compound as acceptor 
        EC 1.4.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.4.9       [+]    With a copper protein as acceptor 
        EC 1.4.99       [+]    With unknown physiological acceptors 
    EC 1.5  [+]      
        EC 1.5.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.5.3       [+]    With oxygen as acceptor 
        EC 1.5.4       [+]    With a disulfide as acceptor 
        EC 1.5.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.5.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.5.8       [+]    With a flavin or flavoprotein as acceptor 
        EC 1.5.98       [+]    With other, known, physiological acceptors 
        EC 1.5.99       [+]    With unknown physiological acceptors 
    EC 1.6  [+]      
        EC 1.6.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.6.2       [+]    With a heme protein as acceptor 
        EC 1.6.3       [+]    With oxygen as acceptor 
        EC 1.6.4       [+]    With a disulfide as acceptor (deleted sub-subclass) 
        EC 1.6.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.6.6       [+]    With a nitrogenous group as acceptor 
        EC 1.6.7       [+]    With an iron-sulfur protein as acceptor (deleted sub-subclass) 
        EC 1.6.8       [+]    With a flavin as acceptor (deleted sub-subclass) 
        EC 1.6.99       [+]    With unknown physiological acceptors 
    EC 1.7  [+]      
        EC 1.7.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.7.2       [+]    With a cytochrome as acceptor 
        EC 1.7.3       [+]    With oxygen as acceptor 
        EC 1.7.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.7.6       [+]    With a nitrogenous group as acceptor 
        EC 1.7.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.7.9       [+]    With a copper protein as acceptor 
        EC 1.7.99       [+]    With unknown physiological acceptors 
    EC 1.8  [+]      
        EC 1.8.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.8.2       [+]    With a cytochrome as acceptor 
        EC 1.8.3       [+]    With oxygen as acceptor 
        EC 1.8.4       [+]    With a disulfide as acceptor 
        EC 1.8.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.8.6       [+]    With a nitrogenous group as acceptor (deleted sub-subclass) 
        EC 1.8.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.8.98       [+]    With other, known, physiological acceptors 
        EC 1.8.99       [+]    With unknown physiological acceptors 
    EC 1.9  [+]      
        EC 1.9.3       [+]    With oxygen as acceptor 
        EC 1.9.6       [+]    With a nitrogenous group as acceptor 
        EC 1.9.98       [+]    With other, known, physiological acceptors 
        EC 1.9.99       [+]    With unknown physiological acceptors 
    EC 1.10  [+]      
        EC 1.10.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.10.2       [+]    With a cytochrome as acceptor 
        EC 1.10.3       [+]    With oxygen as acceptor 
        EC 1.10.5       [+]    With a quinone or related compound as acceptor 
        EC 1.10.9       [+]    With a copper protein as acceptor 
        EC 1.10.99       [+]    With unknown physiological acceptors 
    EC 1.11  [+]      
        EC 1.11.1       [+]      
        EC 1.11.2       [+]      
    EC 1.12  [+]      
        EC 1.12.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.12.2       [+]    With a cytochrome as acceptor 
        EC 1.12.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.12.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.12.98       [+]    With other, known, physiological acceptors 
        EC 1.12.99       [+]    With unknown physiological acceptors 
    EC 1.13  [+]      
        EC 1.13.11       [+]    With incorporation of two atoms of oxygen 
        EC 1.13.12       [+]    With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) 
        EC 1.13.99       [+]    Miscellaneous 
    EC 1.14  [+]      
        EC 1.14.1       [+]    With NADH or NADPH as one donor (deleted sub-subclass) 
        EC 1.14.2       [+]    With ascorbate as one donor (deleted sub-subclass) 
        EC 1.14.3       [+]    With reduced pteridine as one donor (deleted sub-subclass) 
        EC 1.14.11       [+]    With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor 
        EC 1.14.12       [+]    With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor 
        EC 1.14.13       [+]    With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.14       [+]    With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.15       [+]    With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.16       [+]    With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.17       [+]    With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.18       [+]    With another compound as one donor, and incorporation of one atom of oxygen into the other donor 
        EC 1.14.19       [+]    With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water 
        EC 1.14.20       [+]    With 2-oxoglutarate as one donor, and the other dehydrogenated 
        EC 1.14.21       [+]    With NADH or NADPH as one donor, and the other dehydrogenated 
        EC 1.14.99       [+]    Miscellaneous 
    EC 1.15  [+]      
        EC 1.15.1       [+]    Acting on superoxide as acceptor (only sub-subclass identified to date) 
    EC 1.16  [+]      
        EC 1.16.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.16.3       [+]    With oxygen as acceptor 
        EC 1.16.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.16.8       [+]    With a flavin as acceptor 
        EC 1.16.9       [+]    With a copper protein as acceptor 
        EC 1.16.98       [+]    With other, known, physiological acceptors 
        EC 1.16.99       [+]    With unknown physiological acceptors 
    EC 1.17  [+]      
        EC 1.17.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.17.2       [+]    With a cytochrome as acceptor 
        EC 1.17.3       [+]    With oxygen as acceptor 
        EC 1.17.4       [+]    With a disulfide as acceptor 
        EC 1.17.5       [+]    With a quinone or similar compound as acceptor 
        EC 1.17.7       [+]    With an iron-sulfur protein as acceptor 
        EC 1.17.8       [+]    With a flavin as acceptor 
        EC 1.17.9       [+]    With a copper protein as acceptor 
        EC 1.17.98       [+]    With other, known, physiological acceptors 
        EC 1.17.99       [+]    With unknown physiological acceptors 
    EC 1.18  [+]      
        EC 1.18.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.18.2       [+]    With dinitrogen as acceptor (deleted sub-subclass) 
        EC 1.18.3       [+]    With H+ as acceptor (deleted sub-subclass) 
        EC 1.18.6       [+]    With dinitrogen as acceptor 
        EC 1.18.96       [+]    With other, known, acceptors (deleted sub-subclass) 
        EC 1.18.99       [+]    With H+ as acceptor (deleted sub-subclass) 
    EC 1.19  [+]      
        EC 1.19.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.19.6       [+]    With dinitrogen as acceptor 
    EC 1.20  [+]      
        EC 1.20.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.20.2       [+]    With a cytochrome as acceptor 
        EC 1.20.4       [+]    With disulfide as acceptor 
        EC 1.20.9       [+]    With a copper protein as acceptor 
        EC 1.20.98       [+]    With other, known, physiological acceptors 
        EC 1.20.99       [+]    With unknown physiological acceptors 
    EC 1.21  [+]      
        EC 1.21.1       [+]    With NAD+ or NADP+ as acceptor 
        EC 1.21.3       [+]    With oxygen as acceptor 
        EC 1.21.4       [+]    With a disulfide as acceptor 
        EC 1.21.98       [+]    With other, known, physiological acceptors 
        EC 1.21.99       [+]    With unknown physiological acceptors 
    EC 1.22  [+]      
        EC 1.22.1       [+]    With NAD+ or NADP+ as acceptor 
    EC 1.23  [+]      
        EC 1.23.1       [+]    With NADH or NADPH as donor 
        EC 1.23.5       [+]    With a quinone or similar compound as acceptor 
    EC 1.97  [+]      
        EC 1.97.1       [+]    Sole sub-subclass for oxidoreductases that do not belong in the other subclasses 
    EC 1.98  [+]      
    EC 1.99  [+]      
        EC 1.99.1       [+]    Hydroxylases (now covered by EC 1.14) 
        EC 1.99.2       [+]    Oxygenases (now covered by EC 1.13) 
EC 2 [+]   
    EC 2.1  [+]      
        EC 2.1.1       [+]    Methyltransferases 
        EC 2.1.2       [+]    Hydroxymethyl-, formyl- and related transferases 
        EC 2.1.3       [+]    Carboxy- and carbamoyltransferases 
        EC 2.1.4       [+]    Amidinotransferases 
        EC 2.1.5       [+]    Methylenetransferases 
    EC 2.2  [+]      
        EC 2.2.1       [+]    Transketolases and transaldolases 
    EC 2.3  [+]      
        EC 2.3.1       [+]    Transferring groups other than aminoacyl groups 
        EC 2.3.2       [+]    Aminoacyltransferases 
        EC 2.3.3       [+]    Acyl groups converted into alkyl groups on transfer 
    EC 2.4  [+]      
        EC 2.4.1       [+]    Hexosyltransferases 
        EC 2.4.2       [+]    Pentosyltransferases 
        EC 2.4.3       [+]    Sialyltransferases 
        EC 2.4.99       [+]    Transferring other glycosyl groups 
    EC 2.5  [+]      
        EC 2.5.1       [+]    Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) 
    EC 2.6  [+]      
        EC 2.6.1       [+]      
        EC 2.6.2       [+]    Amidinotransferases (deleted sub-subclass) 
        EC 2.6.3       [+]    Oximinotransferases 
        EC 2.6.99       [+]    Transferring other nitrogenous groups 
    EC 2.7  [+]      
        EC 2.7.1       [+]    Phosphotransferases with an alcohol group as acceptor 
        EC 2.7.2       [+]    Phosphotransferases with a carboxy group as acceptor 
        EC 2.7.3       [+]    Phosphotransferases with a nitrogenous group as acceptor 
        EC 2.7.4       [+]    Phosphotransferases with a phosphate group as acceptor 
        EC 2.7.5       [+]    Phosphotransferases with regeneration of donors, apparently catalysing intramolecular transfers (deleted sub-subclass) 
        EC 2.7.6       [+]    Diphosphotransferases 
        EC 2.7.7       [+]    Nucleotidyltransferases 
        EC 2.7.8       [+]    Transferases for other substituted phosphate groups 
        EC 2.7.9       [+]    Phosphotransferases with paired acceptors 
        EC 2.7.10       [+]    Protein-tyrosine kinases 
        EC 2.7.11       [+]    Protein-serine/threonine kinases 
        EC 2.7.12       [+]    Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) 
        EC 2.7.13       [+]    Protein-histidine kinases 
        EC 2.7.14       [+]    Protein-arginine kinases 
        EC 2.7.99       [+]    Other protein kinases 
    EC 2.8  [+]      
        EC 2.8.1       [+]    Sulfurtransferases 
        EC 2.8.2       [+]    Sulfotransferases 
        EC 2.8.3       [+]    CoA-transferases 
        EC 2.8.4       [+]    Transferring alkylthio groups 
        EC 2.8.5       [+]    Thiosulfotransferases 
    EC 2.9  [+]      
        EC 2.9.1       [+]    Selenotransferases 
    EC 2.10  [+]      
        EC 2.10.1       [+]    Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors 
EC 3 [+]   
    EC 3.1  [+]      
        EC 3.1.1       [+]    Carboxylic-ester hydrolases 
        EC 3.1.2       [+]    Thioester hydrolases 
        EC 3.1.3       [+]    Phosphoric-monoester hydrolases 
        EC 3.1.4       [+]    Phosphoric-diester hydrolases 
        EC 3.1.5       [+]    Triphosphoric-monoester hydrolases 
        EC 3.1.6       [+]    Sulfuric-ester hydrolases 
        EC 3.1.7       [+]    Diphosphoric-monoester hydrolases 
        EC 3.1.8       [+]    Phosphoric-triester hydrolases 
        EC 3.1.11       [+]    Exodeoxyribonucleases producing 5′-phosphomonoesters 
        EC 3.1.12       [+]    Exodeoxyribonucleases producing 3′-phosphomonoesters 
        EC 3.1.13       [+]    Exoribonucleases producing 5′-phosphomonoesters 
        EC 3.1.14       [+]    Exoribonucleases producing 3'-phosphomonoesters 
        EC 3.1.15       [+]    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
        EC 3.1.16       [+]    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
        EC 3.1.21       [+]    Endodeoxyribonucleases producing 5'-phosphomonoesters 
        EC 3.1.22       [+]    Endodeoxyribonucleases producing 3'-phosphomonoesters 
        EC 3.1.23       [+]    Site-specific endodeoxyribonucleases: cleavage is sequence specific (deleted sub-subclass) 
        EC 3.1.24       [+]    Site specific endodeoxyribonucleases: cleavage is not sequence specific (deleted sub-subclass) 
        EC 3.1.25       [+]    Site-specific endodeoxyribonucleases that are specific for altered bases 
        EC 3.1.26       [+]    Endoribonucleases producing 5'-phosphomonoesters 
        EC 3.1.27       [+]    Endoribonucleases producing 3'-phosphomonoesters 
        EC 3.1.30       [+]    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
        EC 3.1.31       [+]    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
    EC 3.2  [+]      
        EC 3.2.1       [+]    Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds 
        EC 3.2.2       [+]    Hydrolysing N-glycosyl compounds 
        EC 3.2.3       [+]    Hydrolysing S-glycosyl compounds (deleted sub-subclass) 
    EC 3.3  [+]      
        EC 3.3.1       [+]      
        EC 3.3.2       [+]    Ether hydrolases 
    EC 3.4  [+]      
        EC 3.4.1       [+]    α-Amino-acyl-peptide hydrolases (deleted sub-subclass) 
        EC 3.4.2       [+]    Peptidyl-amino-acid hydrolases (deleted sub-subclass) 
        EC 3.4.3       [+]    Dipeptide hydrolases (deleted sub-subclass) 
        EC 3.4.4       [+]    Peptidyl peptide hydrolases (deleted sub-subclass) 
        EC 3.4.11       [+]    Aminopeptidases 
        EC 3.4.12       [+]    Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass) 
        EC 3.4.13       [+]    Dipeptidases 
        EC 3.4.14       [+]    Dipeptidyl-peptidases and tripeptidyl-peptidases 
        EC 3.4.15       [+]    Peptidyl-dipeptidases 
        EC 3.4.16       [+]    Serine-type carboxypeptidases 
        EC 3.4.17       [+]    Metallocarboxypeptidases 
        EC 3.4.18       [+]    Cysteine-type carboxypeptidases 
        EC 3.4.19       [+]    Omega peptidases 
        EC 3.4.21       [+]    Serine endopeptidases 
        EC 3.4.22       [+]    Cysteine endopeptidases 
        EC 3.4.23       [+]    Aspartic endopeptidases 
        EC 3.4.24       [+]    Metalloendopeptidases 
        EC 3.4.25       [+]    Threonine endopeptidases 
        EC 3.4.26       [+]    Glutamic endopeptidases 
        EC 3.4.99       [+]    Endopeptidases of unknown catalytic mechanism (sub-subclass is currently empty) 
    EC 3.5  [+]      
        EC 3.5.1       [+]    In linear amides 
        EC 3.5.2       [+]    In cyclic amides 
        EC 3.5.3       [+]    In linear amidines 
        EC 3.5.4       [+]    In cyclic amidines 
        EC 3.5.5       [+]    In nitriles 
        EC 3.5.99       [+]    In other compounds 
    EC 3.6  [+]      
        EC 3.6.1       [+]    In phosphorus-containing anhydrides 
        EC 3.6.2       [+]    In sulfonyl-containing anhydrides 
        EC 3.6.3       [+]      
        EC 3.6.4       [+]    Acting on acid anhydrides to facilitate cellular and subcellular movement 
        EC 3.6.5       [+]    Acting on GTP to facilitate cellular and subcellular movement 
    EC 3.7  [+]      
        EC 3.7.1       [+]    In ketonic substances 
    EC 3.8  [+]      
        EC 3.8.1       [+]    In carbon-halide compounds 
        EC 3.8.2       [+]    In phosphorus-halide compounds 
    EC 3.9  [+]      
        EC 3.9.1       [+]    Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date) 
    EC 3.10  [+]      
        EC 3.10.1       [+]    Acting on sulfur-nitrogen bonds (only sub-subclass identified to date) 
    EC 3.11  [+]      
        EC 3.11.1       [+]    Acting on carbon-phosphorus bonds (only sub-subclass identified to date) 
    EC 3.12  [+]      
        EC 3.12.1       [+]    Acting on sulfur-sulfur bonds (only sub-subclass identified to date) 
    EC 3.13  [+]      
        EC 3.13.1       [+]    Acting on carbon-sulfur bonds 
        EC 3.13.2       [+]    Thioether and trialkylsulfonium hydrolases 
EC 4 [+]   
    EC 4.1  [+]      
        EC 4.1.1       [+]    Carboxy-lyases 
        EC 4.1.2       [+]    Aldehyde-lyases 
        EC 4.1.3       [+]    Oxo-acid-lyases 
        EC 4.1.99       [+]    Other carbon-carbon lyases 
    EC 4.2  [+]      
        EC 4.2.1       [+]    Hydro-lyases 
        EC 4.2.2       [+]    Acting on polysaccharides 
        EC 4.2.3       [+]    Acting on phosphates 
        EC 4.2.99       [+]    Other carbon-oxygen lyases 
    EC 4.3  [+]      
        EC 4.3.1       [+]    Ammonia-lyases 
        EC 4.3.2       [+]    Amidine-lyases 
        EC 4.3.3       [+]    Amine-lyases 
        EC 4.3.99       [+]    Other carbon-nitrogen lyases 
    EC 4.4  [+]      
        EC 4.4.1       [+]    Carbon-sulfur lyases (only sub-subclass identified to date) 
    EC 4.5  [+]      
        EC 4.5.1       [+]    Carbon-halide lyases (only sub-subclass identified to date) 
    EC 4.6  [+]      
        EC 4.6.1       [+]    Phosphorus-oxygen lyases (only sub-subclass identified to date) 
    EC 4.7  [+]      
        EC 4.7.1       [+]    carbon-phosphorus lyases (only sub-subclass identified to date) 
    EC 4.8  [+]      
        EC 4.8.1       [+]    Hydro-lyases 
    EC 4.98  [+]      
        EC 4.98.1       [+]    Forming coordination complexes 
    EC 4.99  [+]      
        EC 4.99.1       [+]    Sole sub-subclass for lyases that do not belong in the other subclasses 
EC 5 [+]   
    EC 5.1  [+]      
        EC 5.1.1       [+]    Acting on amino acids and derivatives 
        EC 5.1.2       [+]    Acting on hydroxy acids and derivatives 
        EC 5.1.3       [+]    Acting on carbohydrates and derivatives 
        EC 5.1.99       [+]    Acting on other compounds 
    EC 5.2  [+]      
        EC 5.2.1       [+]    cis-trans Isomerases (only sub-subclass identified to date) 
    EC 5.3  [+]      
        EC 5.3.1       [+]    Interconverting aldoses and ketoses, and related compounds 
        EC 5.3.2       [+]    Interconverting keto- and enol-groups 
        EC 5.3.3       [+]    Transposing C=C bonds 
        EC 5.3.4       [+]    Transposing S-S bonds 
        EC 5.3.99       [+]    Other intramolecular oxidoreductases 
    EC 5.4  [+]      
        EC 5.4.1       [+]    Transferring acyl groups 
        EC 5.4.2       [+]      
        EC 5.4.3       [+]    Transferring amino groups 
        EC 5.4.4       [+]    Transferring hydroxy groups 
        EC 5.4.99       [+]    Transferring other groups 
    EC 5.5  [+]      
        EC 5.5.1       [+]    Intramolecular lyases (only sub-subclass identified to date) 
    EC 5.6  [+]      
        EC 5.6.1       [+]    Enzymes altering polypeptide conformation or assembly 
        EC 5.6.2       [+]    Enzymes altering nucleic acid conformation 
    EC 5.99  [+]      
        EC 5.99.1       [+]    Sole sub-subclass for isomerases that do not belong in the other subclasses 
EC 6 [+]   
    EC 6.1  [+]      
        EC 6.1.1       [+]    Ligases forming aminoacyl-tRNA and related compounds 
        EC 6.1.2       [+]    acid—alcohol ligases (ester synthases) 
        EC 6.1.3       [+]    Cyclo-ligases 
    EC 6.2  [+]      
        EC 6.2.1       [+]    Acid-thiol ligases 
        EC 6.2.2       [+]    Amide---thiol ligases 
    EC 6.3  [+]      
        EC 6.3.1       [+]    Acid—ammonia (or amine) ligases (amide synthases) 
        EC 6.3.2       [+]    Acid—amino-acid ligases (peptide synthases) 
        EC 6.3.3       [+]    Cyclo-ligases 
        EC 6.3.4       [+]    Other carbon-nitrogen ligases 
        EC 6.3.5       [+]    Carbon-nitrogen ligases with glutamine as amido-N-donor 
    EC 6.4  [+]      
        EC 6.4.1       [+]    Ligases that form carbon-carbon bonds (only sub-subclass identified to date) 
    EC 6.5  [+]      
        EC 6.5.1       [+]    Ligases that form phosphoric-ester bonds (only sub-subclass identified to date) 
    EC 6.6  [+]      
        EC 6.6.1       [+]    Forming coordination complexes 
    EC 6.7  [+]      
        EC 6.7.1       [+]    Forming diazo bonds 
EC 7 [+]   
    EC 7.1  [+]      
        EC 7.1.1       [+]    Linked to oxidoreductase reactions 
        EC 7.1.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 
        EC 7.1.3       [+]    Linked to the hydrolysis of diphosphate 
    EC 7.2  [+]      
        EC 7.2.1       [+]    Linked to oxidoreductase reactions 
        EC 7.2.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 
        EC 7.2.4       [+]    Linked to decarboxylation 
    EC 7.3  [+]      
        EC 7.3.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 
    EC 7.4  [+]      
        EC 7.4.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 
    EC 7.5  [+]      
        EC 7.5.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 
    EC 7.6  [+]      
        EC 7.6.2       [+]    Linked to the hydrolysis of a nucleoside triphosphate 


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