The Enzyme Database

Table of Contents

The enzymes in this section of the database are organized as you would find them in the Enzyme-Nomenclature book. Click [+] to expand, and [–] to collapse, any section. Clicking on a heading will open a popup window with information on that class, subclass or sub-subclass.

For a fully expanded list of the classes, subclasses and sub-subclasses, click here

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EC 1 [+]   
    EC 1.1  [+]      
        EC 1.1.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.1.1.1                      alcohol dehydrogenase 
                EC 1.1.1.2                      alcohol dehydrogenase (NADP+) 
                EC 1.1.1.3                      homoserine dehydrogenase 
                EC 1.1.1.4                      (R,R)-butanediol dehydrogenase 
                EC 1.1.1.5                      acetoin dehydrogenase. Now EC 1.1.1.303, diacetyl reductase [(R)-acetoin forming] and EC 1.1.1.304, diacetyl reductase [(S)-acetoin forming] 
                EC 1.1.1.6                      glycerol dehydrogenase 
                EC 1.1.1.7                      propanediol-phosphate dehydrogenase 
                EC 1.1.1.8                      glycerol-3-phosphate dehydrogenase (NAD+) 
                EC 1.1.1.9                      D-xylulose reductase 
                EC 1.1.1.10                      L-xylulose reductase 
                EC 1.1.1.11                      D-arabinitol 4-dehydrogenase 
                EC 1.1.1.12                      L-arabinitol 4-dehydrogenase 
                EC 1.1.1.13                      L-arabinitol 2-dehydrogenase 
                EC 1.1.1.14                      L-iditol 2-dehydrogenase 
                EC 1.1.1.15                      D-iditol 2-dehydrogenase 
                EC 1.1.1.16                      galactitol 2-dehydrogenase 
                EC 1.1.1.17                      mannitol-1-phosphate 5-dehydrogenase 
                EC 1.1.1.18                      inositol 2-dehydrogenase 
                EC 1.1.1.19                      glucuronate reductase 
                EC 1.1.1.20                      glucuronolactone reductase 
                EC 1.1.1.21                      aldose reductase 
                EC 1.1.1.22                      UDP-glucose 6-dehydrogenase 
                EC 1.1.1.23                      histidinol dehydrogenase 
                EC 1.1.1.24                      quinate/shikimate dehydrogenase (NAD+) 
                EC 1.1.1.25                      shikimate dehydrogenase (NADP+) 
                EC 1.1.1.26                      glyoxylate reductase 
                EC 1.1.1.27                      L-lactate dehydrogenase 
                EC 1.1.1.28                      D-lactate dehydrogenase 
                EC 1.1.1.29                      glycerate dehydrogenase 
                EC 1.1.1.30                      3-hydroxybutyrate dehydrogenase 
                EC 1.1.1.31                      3-hydroxyisobutyrate dehydrogenase 
                EC 1.1.1.32                      mevaldate reductase, now included with EC 1.1.1.1, alcohol dehydrogenase. 
                EC 1.1.1.33                      mevaldate reductase (NADPH), now included with EC 1.1.1.2, alcohol dehydrogenase (NADP+). 
                EC 1.1.1.34                      hydroxymethylglutaryl-CoA reductase (NADPH) 
                EC 1.1.1.35                      3-hydroxyacyl-CoA dehydrogenase 
                EC 1.1.1.36                      acetoacetyl-CoA reductase 
                EC 1.1.1.37                      malate dehydrogenase 
                EC 1.1.1.38                      malate dehydrogenase (oxaloacetate-decarboxylating) 
                EC 1.1.1.39                      malate dehydrogenase (decarboxylating) 
                EC 1.1.1.40                      malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) 
                EC 1.1.1.41                      isocitrate dehydrogenase (NAD+) 
                EC 1.1.1.42                      isocitrate dehydrogenase (NADP+) 
                EC 1.1.1.43                      phosphogluconate 2-dehydrogenase 
                EC 1.1.1.44                      phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) 
                EC 1.1.1.45                      L-gulonate 3-dehydrogenase 
                EC 1.1.1.46                      L-arabinose 1-dehydrogenase 
                EC 1.1.1.47                      glucose 1-dehydrogenase [NAD(P)+] 
                EC 1.1.1.48                      D-galactose 1-dehydrogenase 
                EC 1.1.1.49                      glucose-6-phosphate dehydrogenase (NADP+) 
                EC 1.1.1.50                      3α-hydroxysteroid 3-dehydrogenase (Si-specific) 
                EC 1.1.1.51                      3(or 17)β-hydroxysteroid dehydrogenase 
                EC 1.1.1.52                      3α-hydroxycholanate dehydrogenase (NAD+) 
                EC 1.1.1.53                      3α(or 20β)-hydroxysteroid dehydrogenase 
                EC 1.1.1.54                      allyl-alcohol dehydrogenase 
                EC 1.1.1.55                      lactaldehyde reductase (NADPH) 
                EC 1.1.1.56                      ribitol 2-dehydrogenase 
                EC 1.1.1.57                      fructuronate reductase 
                EC 1.1.1.58                      tagaturonate reductase 
                EC 1.1.1.59                      3-hydroxypropionate dehydrogenase 
                EC 1.1.1.60                      2-hydroxy-3-oxopropionate reductase 
                EC 1.1.1.61                      4-hydroxybutyrate dehydrogenase 
                EC 1.1.1.62                      17β-estradiol 17-dehydrogenase 
                EC 1.1.1.63                      testosterone 17β-dehydrogenase. Now EC 1.1.1.239, 3α(17β)-hydroxysteroid dehydrogenase (NAD+) 
                EC 1.1.1.64                      testosterone 17β-dehydrogenase (NADP+) 
                EC 1.1.1.65                      pyridoxine 4-dehydrogenase 
                EC 1.1.1.66                      ω-hydroxydecanoate dehydrogenase 
                EC 1.1.1.67                      mannitol 2-dehydrogenase 
                EC 1.1.1.68                      5,10-methylenetetrahydrofolate reductase. Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H] 
                EC 1.1.1.69                      gluconate 5-dehydrogenase 
                EC 1.1.1.70                       D-glucuronolactone dehydrogenase. Now included with EC 1.2.1.3 aldehyde dehydrogenase (NAD+) 
                EC 1.1.1.71                      alcohol dehydrogenase [NAD(P)+] 
                EC 1.1.1.72                      glycerol dehydrogenase (NADP+) 
                EC 1.1.1.73                      octanol dehydrogenase 
                EC 1.1.1.74                       D-aminopropanol dehydrogenase (reaction due to EC 1.1.1.4 (R,R)-butanediol dehydrogenase) 
                EC 1.1.1.75                      (R)-aminopropanol dehydrogenase 
                EC 1.1.1.76                      (S,S)-butanediol dehydrogenase 
                EC 1.1.1.77                      lactaldehyde reductase 
                EC 1.1.1.78                      methylglyoxal reductase (NADH) 
                EC 1.1.1.79                      glyoxylate reductase (NADP+) 
                EC 1.1.1.80                      isopropanol dehydrogenase (NADP+) 
                EC 1.1.1.81                      hydroxypyruvate reductase 
                EC 1.1.1.82                      malate dehydrogenase (NADP+) 
                EC 1.1.1.83                      D-malate dehydrogenase (decarboxylating) 
                EC 1.1.1.84                      dimethylmalate dehydrogenase 
                EC 1.1.1.85                      3-isopropylmalate dehydrogenase 
                EC 1.1.1.86                      ketol-acid reductoisomerase (NADP+) 
                EC 1.1.1.87                      homoisocitrate dehydrogenase 
                EC 1.1.1.88                      hydroxymethylglutaryl-CoA reductase 
                EC 1.1.1.89                      dihydroxyisovalerate dehydrogenase (isomerizing). Now included with EC 1.1.1.86 ketol-acid reductoisomerase (NADP+) 
                EC 1.1.1.90                      aryl-alcohol dehydrogenase 
                EC 1.1.1.91                      aryl-alcohol dehydrogenase (NADP+) 
                EC 1.1.1.92                      oxaloglycolate reductase (decarboxylating) 
                EC 1.1.1.93                      tartrate dehydrogenase 
                EC 1.1.1.94                      glycerol-3-phosphate dehydrogenase [NAD(P)+] 
                EC 1.1.1.95                      phosphoglycerate dehydrogenase 
                EC 1.1.1.96                      diiodophenylpyruvate reductase 
                EC 1.1.1.97                      3-hydroxybenzyl-alcohol dehydrogenase 
                EC 1.1.1.98                      (R)-2-hydroxy-fatty-acid dehydrogenase 
                EC 1.1.1.99                      (S)-2-hydroxy-fatty-acid dehydrogenase 
                EC 1.1.1.100                      3-oxoacyl-[acyl-carrier-protein] reductase 
                EC 1.1.1.101                      acylglycerone-phosphate reductase 
                EC 1.1.1.102                      3-dehydrosphinganine reductase 
                EC 1.1.1.103                      L-threonine 3-dehydrogenase 
                EC 1.1.1.104                      4-oxoproline reductase 
                EC 1.1.1.105                      all-trans-retinol dehydrogenase (NAD+) 
                EC 1.1.1.106                      pantoate 4-dehydrogenase 
                EC 1.1.1.107                      pyridoxal 4-dehydrogenase 
                EC 1.1.1.108                      carnitine 3-dehydrogenase 
                EC 1.1.1.109                      2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. Now EC 1.3.1.28, 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 
                EC 1.1.1.110                      aromatic 2-oxoacid reductase 
                EC 1.1.1.111                      3-(imidazol-5-yl)lactate dehydrogenase 
                EC 1.1.1.112                      indanol dehydrogenase 
                EC 1.1.1.113                      L-xylose 1-dehydrogenase 
                EC 1.1.1.114                      apiose 1-reductase 
                EC 1.1.1.115                      ribose 1-dehydrogenase (NADP+) 
                EC 1.1.1.116                      D-arabinose 1-dehydrogenase (NAD+) 
                EC 1.1.1.117                      D-arabinose 1-dehydrogenase [NAD(P)+] 
                EC 1.1.1.118                      glucose 1-dehydrogenase (NAD+) 
                EC 1.1.1.119                      glucose 1-dehydrogenase (NADP+) 
                EC 1.1.1.120                      galactose 1-dehydrogenase (NADP+) 
                EC 1.1.1.121                      aldose 1-dehydrogenase (NAD+) 
                EC 1.1.1.122                      D-threo-aldose 1-dehydrogenase 
                EC 1.1.1.123                      sorbose 5-dehydrogenase (NADP+) 
                EC 1.1.1.124                      fructose 5-dehydrogenase (NADP+) 
                EC 1.1.1.125                      2-deoxy-D-gluconate 3-dehydrogenase 
                EC 1.1.1.126                      2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase 
                EC 1.1.1.127                      2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase 
                EC 1.1.1.128                      L-idonate 2-dehydrogenase. The reaction described is covered by EC 1.1.1.264. 
                EC 1.1.1.129                      L-threonate 3-dehydrogenase 
                EC 1.1.1.130                      3-dehydro-L-gulonate 2-dehydrogenase 
                EC 1.1.1.131                      mannuronate reductase 
                EC 1.1.1.132                      GDP-mannose 6-dehydrogenase 
                EC 1.1.1.133                      dTDP-4-dehydrorhamnose reductase 
                EC 1.1.1.134                      dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+) 
                EC 1.1.1.135                      GDP-6-deoxy-D-talose 4-dehydrogenase 
                EC 1.1.1.136                      UDP-N-acetylglucosamine 6-dehydrogenase 
                EC 1.1.1.137                      ribitol-5-phosphate 2-dehydrogenase 
                EC 1.1.1.138                      mannitol 2-dehydrogenase (NADP+) 
                EC 1.1.1.139                      polyol dehydrogenase (NADP+). Now included with EC 1.1.1.21 aldehyde reductase 
                EC 1.1.1.140                      sorbitol-6-phosphate 2-dehydrogenase 
                EC 1.1.1.141                      15-hydroxyprostaglandin dehydrogenase (NAD+) 
                EC 1.1.1.142                      D-pinitol dehydrogenase 
                EC 1.1.1.143                      sequoyitol dehydrogenase 
                EC 1.1.1.144                      perillyl-alcohol dehydrogenase 
                EC 1.1.1.145                      3β-hydroxy-Δ5-steroid dehydrogenase 
                EC 1.1.1.146                      11β-hydroxysteroid dehydrogenase 
                EC 1.1.1.147                      16α-hydroxysteroid dehydrogenase 
                EC 1.1.1.148                      estradiol 17α-dehydrogenase 
                EC 1.1.1.149                      20α-hydroxysteroid dehydrogenase 
                EC 1.1.1.150                      21-hydroxysteroid dehydrogenase (NAD+) 
                EC 1.1.1.151                      21-hydroxysteroid dehydrogenase (NADP+) 
                EC 1.1.1.152                      3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase 
                EC 1.1.1.153                      sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) 
                EC 1.1.1.154                      ureidoglycolate dehydrogenase 
                EC 1.1.1.155                      homoisocitrate dehydrogenase. The enzyme is identical to EC 1.1.1.87, homoisocitrate dehydrogenase 
                EC 1.1.1.156                      glycerol 2-dehydrogenase (NADP+) 
                EC 1.1.1.157                      3-hydroxybutyryl-CoA dehydrogenase 
                EC 1.1.1.158                      UDP-N-acetylmuramate dehydrogenase. Now EC 1.3.1.98, UDP-N-acetylmuramate dehydrogenase 
                EC 1.1.1.159                      7α-hydroxysteroid dehydrogenase 
                EC 1.1.1.160                      dihydrobunolol dehydrogenase 
                EC 1.1.1.161                      cholestanetetraol 26-dehydrogenase. The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase  
                EC 1.1.1.162                      erythrulose reductase 
                EC 1.1.1.163                      cyclopentanol dehydrogenase 
                EC 1.1.1.164                      hexadecanol dehydrogenase 
                EC 1.1.1.165                      2-alkyn-1-ol dehydrogenase 
                EC 1.1.1.166                      hydroxycyclohexanecarboxylate dehydrogenase 
                EC 1.1.1.167                      hydroxymalonate dehydrogenase 
                EC 1.1.1.168                      2-dehydropantolactone reductase (Re-specific) 
                EC 1.1.1.169                      2-dehydropantoate 2-reductase 
                EC 1.1.1.170                      3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating) 
                EC 1.1.1.171                      methylenetetrahydrofolate reductase (NADPH). Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H] 
                EC 1.1.1.172                      2-oxoadipate reductase 
                EC 1.1.1.173                      L-rhamnose 1-dehydrogenase 
                EC 1.1.1.174                      cyclohexane-1,2-diol dehydrogenase 
                EC 1.1.1.175                      D-xylose 1-dehydrogenase 
                EC 1.1.1.176                      12α-hydroxysteroid dehydrogenase 
                EC 1.1.1.177                      glycerol-3-phosphate 1-dehydrogenase (NADP+) 
                EC 1.1.1.178                      3-hydroxy-2-methylbutyryl-CoA dehydrogenase 
                EC 1.1.1.179                      D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) 
                EC 1.1.1.180                       mannonate dehydrogenase (NAD(P)+). Now included with EC 1.1.1.131 mannuronate reductase 
                EC 1.1.1.181                      cholest-5-ene-3β,7α-diol 3β-dehydrogenase 
                EC 1.1.1.182                       fenchol dehydrogenase. Now included with EC 1.1.1.198 (+)-borneol dehydrogenase, EC 1.1.1.227 (-)-borneol dehydrogenase and EC 1.1.1.228 (+)-sabinol dehydrogenase 
                EC 1.1.1.183                      geraniol dehydrogenase (NADP+) 
                EC 1.1.1.184                      carbonyl reductase (NADPH) 
                EC 1.1.1.185                      L-glycol dehydrogenase 
                EC 1.1.1.186                      dTDP-galactose 6-dehydrogenase 
                EC 1.1.1.187                      GDP-4-dehydro-D-rhamnose reductase 
                EC 1.1.1.188                      prostaglandin-F synthase 
                EC 1.1.1.189                      prostaglandin-E2 9-reductase 
                EC 1.1.1.190                      indole-3-acetaldehyde reductase (NADH) 
                EC 1.1.1.191                      indole-3-acetaldehyde reductase (NADPH) 
                EC 1.1.1.192                      long-chain-alcohol dehydrogenase 
                EC 1.1.1.193                      5-amino-6-(5-phosphoribosylamino)uracil reductase 
                EC 1.1.1.194                      coniferyl-alcohol dehydrogenase 
                EC 1.1.1.195                      cinnamyl-alcohol dehydrogenase 
                EC 1.1.1.196                      15-hydroxyprostaglandin-D dehydrogenase (NADP+) 
                EC 1.1.1.197                      15-hydroxyprostaglandin dehydrogenase (NADP+) 
                EC 1.1.1.198                      (+)-borneol dehydrogenase 
                EC 1.1.1.199                      (S)-usnate reductase 
                EC 1.1.1.200                      aldose-6-phosphate reductase (NADPH) 
                EC 1.1.1.201                      7β-hydroxysteroid dehydrogenase (NADP+) 
                EC 1.1.1.202                      1,3-propanediol dehydrogenase 
                EC 1.1.1.203                      uronate dehydrogenase 
                EC 1.1.1.204                      xanthine dehydrogenase. Now EC 1.17.1.4, xanthine dehydrogenase. The enzyme was incorrectly classified as acting on a CH-OH group 
                EC 1.1.1.205                      IMP dehydrogenase 
                EC 1.1.1.206                      tropinone reductase I 
                EC 1.1.1.207                      (-)-menthol dehydrogenase 
                EC 1.1.1.208                      (+)-neomenthol dehydrogenase 
                EC 1.1.1.209                      3(or 17)α-hydroxysteroid dehydrogenase 
                EC 1.1.1.210                      3β(or 20α)-hydroxysteroid dehydrogenase 
                EC 1.1.1.211                      long-chain-3-hydroxyacyl-CoA dehydrogenase 
                EC 1.1.1.212                      3-oxoacyl-[acyl-carrier-protein] reductase (NADH) 
                EC 1.1.1.213                      3α-hydroxysteroid 3-dehydrogenase (Re-specific) 
                EC 1.1.1.214                      2-dehydropantolactone reductase (Si-specific) 
                EC 1.1.1.215                      gluconate 2-dehydrogenase 
                EC 1.1.1.216                      farnesol dehydrogenase (NADP+) 
                EC 1.1.1.217                      benzyl-2-methyl-hydroxybutyrate dehydrogenase 
                EC 1.1.1.218                      morphine 6-dehydrogenase 
                EC 1.1.1.219                      dihydroflavonol 4-reductase 
                EC 1.1.1.220                      6-pyruvoyltetrahydropterin 2′-reductase 
                EC 1.1.1.221                      vomifoliol dehydrogenase 
                EC 1.1.1.222                      (R)-4-hydroxyphenyllactate dehydrogenase. Now included with EC 1.1.1.110, aromatic 2-oxoacid reductase 
                EC 1.1.1.223                      isopiperitenol dehydrogenase 
                EC 1.1.1.224                      mannose-6-phosphate 6-reductase 
                EC 1.1.1.225                      chlordecone reductase 
                EC 1.1.1.226                      4-hydroxycyclohexanecarboxylate dehydrogenase 
                EC 1.1.1.227                      (-)-borneol dehydrogenase 
                EC 1.1.1.228                      (+)-sabinol dehydrogenase 
                EC 1.1.1.229                      diethyl 2-methyl-3-oxosuccinate reductase 
                EC 1.1.1.230                      3α-hydroxyglycyrrhetinate dehydrogenase 
                EC 1.1.1.231                      15-hydroxyprostaglandin-I dehydrogenase (NADP+) 
                EC 1.1.1.232                      15-hydroxyicosatetraenoate dehydrogenase 
                EC 1.1.1.233                      N-acylmannosamine 1-dehydrogenase 
                EC 1.1.1.234                      flavanone 4-reductase 
                EC 1.1.1.235                      8-oxocoformycin reductase 
                EC 1.1.1.236                      tropinone reductase II 
                EC 1.1.1.237                      hydroxyphenylpyruvate reductase 
                EC 1.1.1.238                      12β-hydroxysteroid dehydrogenase 
                EC 1.1.1.239                      3α(17β)-hydroxysteroid dehydrogenase (NAD+) 
                EC 1.1.1.240                      N-acetylhexosamine 1-dehydrogenase 
                EC 1.1.1.241                      6-endo-hydroxycineole dehydrogenase 
                EC 1.1.1.242                      zeatin reductase. Now EC 1.3.1.69, zeatin reductase 
                EC 1.1.1.243                      carveol dehydrogenase 
                EC 1.1.1.244                      methanol dehydrogenase 
                EC 1.1.1.245                      cyclohexanol dehydrogenase 
                EC 1.1.1.246                      pterocarpin synthase. This activity is now known to be catalysed by two enzymes, vestitone reductase (EC 1.1.1.348) and medicarpin synthase (EC 4.2.1.139). 
                EC 1.1.1.247                      codeinone reductase (NADPH) 
                EC 1.1.1.248                      salutaridine reductase (NADPH) 
                EC 1.1.1.249                      Provisional entry deleted. Revised and reinstated as EC 2.5.1.46 deoxyhypusine synthase 
                EC 1.1.1.250                      D-arabinitol 2-dehydrogenase 
                EC 1.1.1.251                      galactitol-1-phosphate 5-dehydrogenase 
                EC 1.1.1.252                      tetrahydroxynaphthalene reductase 
                EC 1.1.1.253                      pteridine reductase. Now EC 1.5.1.33, pteridine reductase 
                EC 1.1.1.254                      (S)-carnitine 3-dehydrogenase 
                EC 1.1.1.255                      mannitol dehydrogenase 
                EC 1.1.1.256                      fluoren-9-ol dehydrogenase 
                EC 1.1.1.257                      4-(hydroxymethyl)benzenesulfonate dehydrogenase 
                EC 1.1.1.258                      6-hydroxyhexanoate dehydrogenase 
                EC 1.1.1.259                      3-hydroxypimeloyl-CoA dehydrogenase 
                EC 1.1.1.260                      sulcatone reductase 
                EC 1.1.1.261                      sn-glycerol-1-phosphate dehydrogenase 
                EC 1.1.1.262                      4-hydroxythreonine-4-phosphate dehydrogenase 
                EC 1.1.1.263                      1,5-anhydro-D-fructose reductase 
                EC 1.1.1.264                      L-idonate 5-dehydrogenase 
                EC 1.1.1.265                      3-methylbutanal reductase 
                EC 1.1.1.266                      dTDP-4-dehydro-6-deoxyglucose reductase 
                EC 1.1.1.267                      1-deoxy-D-xylulose-5-phosphate reductoisomerase 
                EC 1.1.1.268                      2-(R)-hydroxypropyl-CoM dehydrogenase 
                EC 1.1.1.269                      2-(S)-hydroxypropyl-CoM dehydrogenase 
                EC 1.1.1.270                      3β-hydroxysteroid 3-dehydrogenase 
                EC 1.1.1.271                      GDP-L-fucose synthase 
                EC 1.1.1.272                      D-2-hydroxyacid dehydrogenase (NADP+) 
                EC 1.1.1.273                      vellosimine dehydrogenase 
                EC 1.1.1.274                      2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) 
                EC 1.1.1.275                      (+)-trans-carveol dehydrogenase 
                EC 1.1.1.276                      serine 3-dehydrogenase (NADP+) 
                EC 1.1.1.277                      3β-hydroxy-5β-steroid dehydrogenase 
                EC 1.1.1.278                      3β-hydroxy-5α-steroid dehydrogenase 
                EC 1.1.1.279                      (R)-3-hydroxyacid-ester dehydrogenase 
                EC 1.1.1.280                      (S)-3-hydroxyacid-ester dehydrogenase 
                EC 1.1.1.281                      GDP-4-dehydro-6-deoxy-D-mannose reductase 
                EC 1.1.1.282                      quinate/shikimate dehydrogenase [NAD(P)+] 
                EC 1.1.1.283                      methylglyoxal reductase (NADPH) 
                EC 1.1.1.284                      S-(hydroxymethyl)glutathione dehydrogenase 
                EC 1.1.1.285                      3′′-deamino-3′′-oxonicotianamine reductase 
                EC 1.1.1.286                      isocitrate—homoisocitrate dehydrogenase 
                EC 1.1.1.287                      D-arabinitol dehydrogenase (NADP+) 
                EC 1.1.1.288                      xanthoxin dehydrogenase 
                EC 1.1.1.289                      sorbose reductase 
                EC 1.1.1.290                      4-phosphoerythronate dehydrogenase 
                EC 1.1.1.291                      2-hydroxymethylglutarate dehydrogenase 
                EC 1.1.1.292                      1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) 
                EC 1.1.1.293                      tropinone reductase I. This enzyme was already in the Enzyme List as EC 1.1.1.206, tropine dehydrogenase so EC 1.1.1.293 has been withdrawn at the public-review stage 
                EC 1.1.1.294                      chlorophyll(ide) b reductase 
                EC 1.1.1.295                      momilactone-A synthase 
                EC 1.1.1.296                      dihydrocarveol dehydrogenase 
                EC 1.1.1.297                      limonene-1,2-diol dehydrogenase 
                EC 1.1.1.298                      3-hydroxypropionate dehydrogenase (NADP+) 
                EC 1.1.1.299                      malate dehydrogenase [NAD(P)+] 
                EC 1.1.1.300                      NADP-retinol dehydrogenase 
                EC 1.1.1.301                      D-arabitol-phosphate dehydrogenase 
                EC 1.1.1.302                      2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5′-phosphate reductase 
                EC 1.1.1.303                      diacetyl reductase [(R)-acetoin forming] 
                EC 1.1.1.304                      diacetyl reductase [(S)-acetoin forming] 
                EC 1.1.1.305                      UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) 
                EC 1.1.1.306                      S-(hydroxymethyl)mycothiol dehydrogenase 
                EC 1.1.1.307                      D-xylose reductase [NAD(P)H] 
                EC 1.1.1.308                      sulfopropanediol 3-dehydrogenase 
                EC 1.1.1.309                      phosphonoacetaldehyde reductase (NADH) 
                EC 1.1.1.310                      (S)-sulfolactate dehydrogenase 
                EC 1.1.1.311                      (S)-1-phenylethanol dehydrogenase 
                EC 1.1.1.312                      2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase 
                EC 1.1.1.313                      sulfoacetaldehyde reductase (NADPH) 
                EC 1.1.1.314                      germacrene A alcohol dehydrogenase. Now known to be catalyzed by EC 1.14.14.95, germacrene A hydroxylase 
                EC 1.1.1.315                      11-cis-retinol dehydrogenase 
                EC 1.1.1.316                      L-galactose 1-dehydrogenase 
                EC 1.1.1.317                      perakine reductase 
                EC 1.1.1.318                      eugenol synthase 
                EC 1.1.1.319                      isoeugenol synthase 
                EC 1.1.1.320                      benzil reductase [(S)-benzoin forming] 
                EC 1.1.1.321                      benzil reductase [(R)-benzoin forming] 
                EC 1.1.1.322                      (–)-endo-fenchol dehydrogenase 
                EC 1.1.1.323                      (+)-thujan-3-ol dehydrogenase 
                EC 1.1.1.324                      8-hydroxygeraniol dehydrogenase 
                EC 1.1.1.325                      sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) 
                EC 1.1.1.326                      zerumbone synthase 
                EC 1.1.1.327                      5-exo-hydroxycamphor dehydrogenase 
                EC 1.1.1.328                      nicotine blue oxidoreductase 
                EC 1.1.1.329                      2-deoxy-scyllo-inosamine dehydrogenase 
                EC 1.1.1.330                      very-long-chain 3-oxoacyl-CoA reductase 
                EC 1.1.1.331                      secoisolariciresinol dehydrogenase 
                EC 1.1.1.332                      chanoclavine-I dehydrogenase 
                EC 1.1.1.333                      decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose 2-reductase 
                EC 1.1.1.334                      methylecgonone reductase 
                EC 1.1.1.335                      UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase 
                EC 1.1.1.336                      UDP-N-acetyl-D-mannosamine dehydrogenase 
                EC 1.1.1.337                      L-2-hydroxycarboxylate dehydrogenase (NAD+) 
                EC 1.1.1.338                      (2R)-3-sulfolactate dehydrogenase (NADP+) 
                EC 1.1.1.339                      dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) 
                EC 1.1.1.340                      1-deoxy-11β-hydroxypentalenate dehydrogenase 
                EC 1.1.1.341                      CDP-abequose synthase 
                EC 1.1.1.342                      CDP-paratose synthase 
                EC 1.1.1.343                      phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) 
                EC 1.1.1.344                      dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+] 
                EC 1.1.1.345                      D-2-hydroxyacid dehydrogenase (NAD+) 
                EC 1.1.1.346                      2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) 
                EC 1.1.1.347                      geraniol dehydrogenase (NAD+) 
                EC 1.1.1.348                      (3R)-2′-hydroxyisoflavanone reductase 
                EC 1.1.1.349                      norsolorinic acid ketoreductase 
                EC 1.1.1.350                      ureidoglycolate dehydrogenase (NAD+) 
                EC 1.1.1.351                      phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating] 
                EC 1.1.1.352                      5′-hydroxyaverantin dehydrogenase 
                EC 1.1.1.353                      versiconal hemiacetal acetate reductase 
                EC 1.1.1.354                      farnesol dehydrogenase (NAD+) 
                EC 1.1.1.355                      2′-dehydrokanamycin reductase 
                EC 1.1.1.356                      GDP-L-colitose synthase 
                EC 1.1.1.357                      3α-hydroxysteroid 3-dehydrogenase 
                EC 1.1.1.358                      2-dehydropantolactone reductase 
                EC 1.1.1.359                      aldose 1-dehydrogenase [NAD(P)+] 
                EC 1.1.1.360                      glucose/galactose 1-dehydrogenase 
                EC 1.1.1.361                      glucose-6-phosphate 3-dehydrogenase 
                EC 1.1.1.362                      aklaviketone reductase 
                EC 1.1.1.363                      glucose-6-phosphate dehydrogenase [NAD(P)+] 
                EC 1.1.1.364                      dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase 
                EC 1.1.1.365                      D-galacturonate reductase 
                EC 1.1.1.366                      L-idonate 5-dehydrogenase (NAD+) 
                EC 1.1.1.367                      UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase 
                EC 1.1.1.368                      6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase 
                EC 1.1.1.369                      D-chiro-inositol 1-dehydrogenase 
                EC 1.1.1.370                      scyllo-inositol 2-dehydrogenase (NAD+) 
                EC 1.1.1.371                      scyllo-inositol 2-dehydrogenase (NADP+) 
                EC 1.1.1.372                      D/L-glyceraldehyde reductase 
                EC 1.1.1.373                      sulfolactaldehyde 3-reductase 
                EC 1.1.1.374                      UDP-N-acetylglucosamine 3-dehydrogenase 
                EC 1.1.1.375                      L-2-hydroxycarboxylate dehydrogenase [NAD(P)+] 
                EC 1.1.1.376                      L-arabinose 1-dehydrogenase [NAD(P)+] 
                EC 1.1.1.377                      L-rhamnose 1-dehydrogenase (NADP+) 
                EC 1.1.1.378                      L-rhamnose 1-dehydrogenase [NAD(P)+] 
                EC 1.1.1.379                      (R)-mandelate dehydrogenase 
                EC 1.1.1.380                      L-gulonate 5-dehydrogenase 
                EC 1.1.1.381                      3-hydroxy acid dehydrogenase 
                EC 1.1.1.382                      ketol-acid reductoisomerase (NAD+) 
                EC 1.1.1.383                      ketol-acid reductoisomerase [NAD(P)+] 
                EC 1.1.1.384                      dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase 
                EC 1.1.1.385                      dihydroanticapsin dehydrogenase 
                EC 1.1.1.386                      ipsdienol dehydrogenase 
                EC 1.1.1.387                      L-serine 3-dehydrogenase (NAD+) 
                EC 1.1.1.388                      glucose-6-phosphate dehydrogenase (NAD+) 
                EC 1.1.1.389                      2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase 
                EC 1.1.1.390                      sulfoquinovose 1-dehydrogenase 
                EC 1.1.1.391                      3β-hydroxycholanate 3-dehydrogenase (NAD+) 
                EC 1.1.1.392                      3α-hydroxycholanate dehydrogenase (NADP+) 
                EC 1.1.1.393                      3β-hydroxycholanate 3-dehydrogenase (NADP+) 
                EC 1.1.1.394                      aurachin B dehydrogenase 
                EC 1.1.1.395                      3α-hydroxy bile acid-CoA-ester 3-dehydrogenase 
                EC 1.1.1.396                      bacteriochlorophyllide a dehydrogenase 
                EC 1.1.1.397                      β-methylindole-3-pyruvate reductase 
                EC 1.1.1.398                      2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase 
                EC 1.1.1.399                      2-oxoglutarate reductase 
                EC 1.1.1.400                      2-methyl-1,2-propanediol dehydrogenase 
                EC 1.1.1.401                      2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) 
                EC 1.1.1.402                      D-erythritol 1-phosphate dehydrogenase 
                EC 1.1.1.403                      D-threitol dehydrogenase (NAD+) 
                EC 1.1.1.404                      tetrachlorobenzoquinone reductase 
                EC 1.1.1.405                      ribitol-5-phosphate 2-dehydrogenase (NADP+) 
                EC 1.1.1.406                      galactitol 2-dehydrogenase (L-tagatose-forming) 
                EC 1.1.1.407                      D-altritol 5-dehydrogenase 
                EC 1.1.1.408                      4-phospho-D-threonate 3-dehydrogenase 
                EC 1.1.1.409                      4-phospho-D-erythronate 3-dehydrogenase 
                EC 1.1.1.410                      D-erythronate 2-dehydrogenase 
                EC 1.1.1.411                      L-threonate 2-dehydrogenase 
                EC 1.1.1.412                      2-alkyl-3-oxoalkanoate reductase 
                EC 1.1.1.413                      A-factor type γ-butyrolactone 1′-reductase (1S-forming) 
                EC 1.1.1.414                      L-galactonate 5-dehydrogenase 
                EC 1.1.1.415                      noscapine synthase 
                EC 1.1.1.416                      isopyridoxal dehydrogenase (5-pyridoxolactone-forming) 
                EC 1.1.1.417                      3β-hydroxysteroid-4β-carboxylate 3-dehydrogenase (decarboxylating) 
                EC 1.1.1.418                      plant 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating) 
                EC 1.1.1.419                      nepetalactol dehydrogenase 
                EC 1.1.1.420                      D-apiose dehydrogenase 
                EC 1.1.1.421                      D-apionate oxidoisomerase 
                EC 1.1.1.422                      pseudoephedrine dehydrogenase 
                EC 1.1.1.423                      (1R,2S)-ephedrine 1-dehydrogenase 
                EC 1.1.1.424                      D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) 
                EC 1.1.1.425                      levoglucosan dehydrogenase 
                EC 1.1.1.426                      UDP-N-acetyl-α-D-quinovosamine dehydrogenase 
                EC 1.1.1.427                      D-arabinose 1-dehydrogenase (NADP+) 
                EC 1.1.1.428                      4-methylthio 2-oxobutanoate reductase (NADH) 
                EC 1.1.1.429                      (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase 
                EC 1.1.1.430                      D-xylose reductase (NADH) 
                EC 1.1.1.431                      D-xylose reductase (NADPH) 
                EC 1.1.1.432                      6-dehydroglucose reductase 
                EC 1.1.1.433                      sulfoacetaldehyde reductase (NADH) 
                EC 1.1.1.434                      2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase 
                EC 1.1.1.435                      L-fucose dehydrogenase 
                EC 1.1.1.436                      lactate dehydrogenase (NAD+,ferredoxin) 
                EC 1.1.1.437                      5-dehydrofumagillol 5-reductase 
        EC 1.1.2       []    With a cytochrome as acceptor 
                EC 1.1.2.1                      glycerolphosphate dehydrogenase. As the acceptor is now known, the enzyme has been transferred to EC 1.1.5.3, glycerol-3-phosphate dehydrogenase. 
                EC 1.1.2.2                      mannitol dehydrogenase (cytochrome) 
                EC 1.1.2.3                      L-lactate dehydrogenase (cytochrome) 
                EC 1.1.2.4                      D-lactate dehydrogenase (cytochrome) 
                EC 1.1.2.5                      D-lactate dehydrogenase (cytochrome c-553) 
                EC 1.1.2.6                      polyvinyl alcohol dehydrogenase (cytochrome) 
                EC 1.1.2.7                      methanol dehydrogenase (cytochrome c) 
                EC 1.1.2.8                      alcohol dehydrogenase (cytochrome c) 
                EC 1.1.2.9                      1-butanol dehydrogenase (cytochrome c) 
                EC 1.1.2.10                      lanthanide-dependent methanol dehydrogenase 
                EC 1.1.2.11                      glucoside 3-dehydrogenase (cytochrome c) 
        EC 1.1.3       []    With oxygen as acceptor 
                EC 1.1.3.1                       glycolate oxidase. Now included with EC 1.1.3.15 (S)-2-hydroxy-acid oxidase 
                EC 1.1.3.2                      L-lactate oxidase 
                EC 1.1.3.3                      malate oxidase. Now classified as EC 1.1.5.4, malate dehydrogenase (quinone).  
                EC 1.1.3.4                      glucose oxidase 
                EC 1.1.3.5                      hexose oxidase 
                EC 1.1.3.6                      cholesterol oxidase 
                EC 1.1.3.7                      aryl-alcohol oxidase 
                EC 1.1.3.8                      L-gulonolactone oxidase 
                EC 1.1.3.9                      galactose oxidase 
                EC 1.1.3.10                      pyranose oxidase 
                EC 1.1.3.11                      L-sorbose oxidase 
                EC 1.1.3.12                      pyridoxine 4-oxidase 
                EC 1.1.3.13                      alcohol oxidase 
                EC 1.1.3.14                      catechol oxidase (dimerizing) 
                EC 1.1.3.15                      (S)-2-hydroxy-acid oxidase 
                EC 1.1.3.16                      ecdysone oxidase 
                EC 1.1.3.17                      choline oxidase 
                EC 1.1.3.18                      secondary-alcohol oxidase 
                EC 1.1.3.19                      4-hydroxymandelate oxidase (decarboxylating) 
                EC 1.1.3.20                      long-chain-alcohol oxidase 
                EC 1.1.3.21                      glycerol-3-phosphate oxidase 
                EC 1.1.3.22                      xanthine oxidase. Now EC 1.17.3.2, xanthine oxidase. The enzyme was incorrectly classified as acting on a CH-OH group 
                EC 1.1.3.23                      thiamine oxidase 
                EC 1.1.3.24                      L-galactonolactone oxidase. Now EC 1.3.3.12, L-galactonolactone oxidase. The enzyme had been incorrectly classified as acting upon a CH-OH donor rather than a CH-CH donor 
                EC 1.1.3.25                      cellobiose oxidase. Now included with EC 1.1.99.18, cellobiose dehydrogenase (acceptor) 
                EC 1.1.3.26                      columbamine oxidase. Now EC 1.21.3.2, columbamine oxidase 
                EC 1.1.3.27                      hydroxyphytanate oxidase 
                EC 1.1.3.28                      nucleoside oxidase 
                EC 1.1.3.29                      N-acylhexosamine oxidase 
                EC 1.1.3.30                      polyvinyl-alcohol oxidase 
                EC 1.1.3.31                       methanol oxidase. Cannot be distinguished from EC 1.1.3.13, alcohol oxidase 
                EC 1.1.3.32                      (S)-stylopine synthase. Now EC 1.14.21.1, (S)-stylopine synthase 
                EC 1.1.3.33                      S-cheilanthifoline synthase. Now EC 1.14.21.2, (S)-cheilanthifoline synthase 
                EC 1.1.3.34                      berbamunine synthase. Now EC 1.14.21.3, berbamunine synthase 
                EC 1.1.3.35                      salutaridine synthase. Now EC 1.14.21.4, salutaridine synthase 
                EC 1.1.3.36                      (S)-canadine synthase. Now EC 1.14.21.5, (S)-canadine synthase 
                EC 1.1.3.37                      D-arabinono-1,4-lactone oxidase 
                EC 1.1.3.38                      vanillyl-alcohol oxidase 
                EC 1.1.3.39                      nucleoside oxidase (H2O2-forming) 
                EC 1.1.3.40                      D-mannitol oxidase 
                EC 1.1.3.41                      alditol oxidase 
                EC 1.1.3.42                      prosolanapyrone-II oxidase 
                EC 1.1.3.43                      paromamine 6′-oxidase 
                EC 1.1.3.44                      6′′′-hydroxyneomycin C oxidase 
                EC 1.1.3.45                      aclacinomycin-N oxidase 
                EC 1.1.3.46                      4-hydroxymandelate oxidase 
                EC 1.1.3.47                      5-(hydroxymethyl)furfural oxidase 
                EC 1.1.3.48                      3-deoxy-α-D-manno-octulosonate 8-oxidase 
                EC 1.1.3.49                      (R)-mandelonitrile oxidase 
                EC 1.1.3.50                      C-glycoside oxidase 
        EC 1.1.4       []    With a disulfide as acceptor 
                EC 1.1.4.1                      vitamin-K-epoxide reductase (warfarin-sensitive). Now EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive) 
                EC 1.1.4.2                      vitamin-K-epoxide reductase (warfarin-insensitive). Now EC 1.17.4.5, vitamin-K-epoxide reductase (warfarin-insensitive) 
        EC 1.1.5       []    With a quinone or similar compound as acceptor 
                EC 1.1.5.1                       cellobiose dehydrogenase (quinone). Now known to be proteolytic product of EC 1.1.99.18, cellobiose dehydrogenase (acceptor) 
                EC 1.1.5.2                      glucose 1-dehydrogenase (PQQ, quinone) 
                EC 1.1.5.3                      glycerol-3-phosphate dehydrogenase 
                EC 1.1.5.4                      malate dehydrogenase (quinone) 
                EC 1.1.5.5                      alcohol dehydrogenase (quinone) 
                EC 1.1.5.6                      formate dehydrogenase-N. Now EC 1.17.5.3, formate dehydrogenase-N 
                EC 1.1.5.7                      cyclic alcohol dehydrogenase (quinone) 
                EC 1.1.5.8                      quinate/shikimate dehydrogenase (quinone) 
                EC 1.1.5.9                      glucose 1-dehydrogenase (FAD, quinone) 
                EC 1.1.5.10                      D-2-hydroxyacid dehydrogenase (quinone) 
                EC 1.1.5.11                      1-butanol dehydrogenase (quinone) 
                EC 1.1.5.12                      D-lactate dehydrogenase (quinone) 
                EC 1.1.5.13                      (S)-2-hydroxyglutarate dehydrogenase 
                EC 1.1.5.14                      fructose 5-dehydrogenase 
        EC 1.1.7       []    With an iron-sulfur protein as acceptor 
                EC 1.1.7.1                      4-hydroxybenzoyl-CoA reductase 
        EC 1.1.9       []    With a copper protein as acceptor 
                EC 1.1.9.1                      alcohol dehydrogenase (azurin) 
        EC 1.1.98       []    With other, known, physiological acceptors 
                EC 1.1.98.1                      Now EC 1.1.9.1, alcohol dehydrogenase (azurin) 
                EC 1.1.98.2                      glucose-6-phosphate dehydrogenase (coenzyme-F420) 
                EC 1.1.98.3                      decaprenylphospho-β-D-ribofuranose 2-dehydrogenase 
                EC 1.1.98.4                      F420H2:quinone oxidoreductase 
                EC 1.1.98.5                      secondary-alcohol dehydrogenase (coenzyme-F420) 
                EC 1.1.98.6                      ribonucleoside-triphosphate reductase (formate) 
                EC 1.1.98.7                      serine-type anaerobic sulfatase-maturating enzyme 
        EC 1.1.99       []    With unknown physiological acceptors 
                EC 1.1.99.1                      choline dehydrogenase 
                EC 1.1.99.2                      L-2-hydroxyglutarate dehydrogenase 
                EC 1.1.99.3                      gluconate 2-dehydrogenase (acceptor) 
                EC 1.1.99.4                      dehydrogluconate dehydrogenase 
                EC 1.1.99.5                      glycerol-3-phosphate dehydrogenase. As the acceptor is now known, the enzyme has been transferred to EC 1.1.5.3, glycerol-3-phosphate dehydrogenase. 
                EC 1.1.99.6                      D-lactate dehydrogenase (acceptor) 
                EC 1.1.99.7                      lactate—malate transhydrogenase 
                EC 1.1.99.8                      alcohol dehydrogenase (acceptor). Now EC 1.1.2.7, methanol dehydrogenase (cytochrome c) and EC 1.1.2.8, alcohol dehydrogenase (cytochrome c). 
                EC 1.1.99.9                      pyridoxine 5-dehydrogenase 
                EC 1.1.99.10                      glucose dehydrogenase (acceptor). Now EC 1.1.5.9, glucose 1-dehydrogenase (FAD, quinone) 
                EC 1.1.99.11                      fructose 5-dehydrogenase, now classified as EC 1.1.5.14, fructose 5-dehydrogenase. 
                EC 1.1.99.12                      sorbose dehydrogenase 
                EC 1.1.99.13                      glucoside 3-dehydrogenase (acceptor) 
                EC 1.1.99.14                      glycolate dehydrogenase 
                EC 1.1.99.15                      5,10-methylenetetrahydrofolate reductase (FADH2). Now EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H] 
                EC 1.1.99.16                      malate dehydrogenase (acceptor). As the acceptor is now known, the enzyme has been transferred to EC 1.1.5.4, malate dehydrogenase (quinone). 
                EC 1.1.99.17                      glucose dehydrogenase (pyrroloquinoline-quinone). Now EC 1.1.5.2, quinoprotein glucose dehydrogenase 
                EC 1.1.99.18                      cellobiose dehydrogenase (acceptor) 
                EC 1.1.99.19                      uracil dehydrogenase. Now EC 1.17.99.4, uracil/thymine dehydrogenase 
                EC 1.1.99.20                      alkan-1-ol dehydrogenase (acceptor) 
                EC 1.1.99.21                      D-sorbitol dehydrogenase (acceptor) 
                EC 1.1.99.22                      glycerol dehydrogenase (acceptor) 
                EC 1.1.99.23                      polyvinyl-alcohol dehydrogenase (acceptor). Now EC 1.1.2.6, polyvinyl alcohol dehydrogenase (cytochrome) 
                EC 1.1.99.24                      hydroxyacid-oxoacid transhydrogenase 
                EC 1.1.99.25                      quinate dehydrogenase (pyrroloquinoline-quinone). Now EC 1.1.5.8, quinate dehydrogenase (quinone) 
                EC 1.1.99.26                      3-hydroxycyclohexanone dehydrogenase 
                EC 1.1.99.27                      (R)-pantolactone dehydrogenase (flavin) 
                EC 1.1.99.28                      glucose-fructose oxidoreductase 
                EC 1.1.99.29                      pyranose dehydrogenase (acceptor) 
                EC 1.1.99.30                      2-oxo-acid reductase 
                EC 1.1.99.31                      (S)-mandelate dehydrogenase 
                EC 1.1.99.32                      L-sorbose 1-dehydrogenase 
                EC 1.1.99.33                      formate dehydrogenase (acceptor). Now EC 1.17.99.7, formate dehydrogenase (acceptor) 
                EC 1.1.99.34                      glucose-6-phosphate dehydrogenase (coenzyme-F420). As the acceptor is now known, the enzyme has been transferred to EC 1.1.98.2, glucose-6-phosphate dehydrogenase (coenzyme-F420) 
                EC 1.1.99.35                      soluble quinoprotein glucose dehydrogenase 
                EC 1.1.99.36                      alcohol dehydrogenase (nicotinoprotein) 
                EC 1.1.99.37                      methanol dehydrogenase (nicotinoprotein) 
                EC 1.1.99.38                      2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) 
                EC 1.1.99.39                      D-2-hydroxyglutarate dehydrogenase 
                EC 1.1.99.40                      (R)-2-hydroxyglutarate—pyruvate transhydrogenase 
                EC 1.1.99.41                      3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase 
                EC 1.1.99.42                      4-pyridoxic acid dehydrogenase 
    EC 1.2  [+]      
        EC 1.2.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.2.1.1                       glutathione-dependent formaldehyde dehydrogenase. This enzyme was classified on the basis of an incorrect reaction. It has been replaced by two enzymes, EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase 
                EC 1.2.1.2                      formate dehydrogenase. Now EC 1.17.1.9, formate dehydrogenase 
                EC 1.2.1.3                      aldehyde dehydrogenase (NAD+) 
                EC 1.2.1.4                      aldehyde dehydrogenase (NADP+) 
                EC 1.2.1.5                      aldehyde dehydrogenase [NAD(P)+] 
                EC 1.2.1.6                       benzaldehyde dehydrogenase 
                EC 1.2.1.7                      benzaldehyde dehydrogenase (NADP+) 
                EC 1.2.1.8                      betaine-aldehyde dehydrogenase 
                EC 1.2.1.9                      glyceraldehyde-3-phosphate dehydrogenase (NADP+) 
                EC 1.2.1.10                      acetaldehyde dehydrogenase (acetylating) 
                EC 1.2.1.11                      aspartate-semialdehyde dehydrogenase 
                EC 1.2.1.12                      glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 
                EC 1.2.1.13                      glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) 
                EC 1.2.1.14                      IMP dehydrogenase. Now EC 1.1.1.205, IMP dehydrogenase 
                EC 1.2.1.15                      malonate-semialdehyde dehydrogenase 
                EC 1.2.1.16                      succinate-semialdehyde dehydrogenase [NAD(P)+] 
                EC 1.2.1.17                      glyoxylate dehydrogenase (acylating) 
                EC 1.2.1.18                      malonate-semialdehyde dehydrogenase (acetylating) 
                EC 1.2.1.19                      aminobutyraldehyde dehydrogenase 
                EC 1.2.1.20                      glutarate-semialdehyde dehydrogenase 
                EC 1.2.1.21                      glycolaldehyde dehydrogenase 
                EC 1.2.1.22                      lactaldehyde dehydrogenase 
                EC 1.2.1.23                      2-oxoaldehyde dehydrogenase (NAD+) 
                EC 1.2.1.24                      succinate-semialdehyde dehydrogenase (NAD+) 
                EC 1.2.1.25                      branched-chain α-keto acid dehydrogenase system 
                EC 1.2.1.26                      2,5-dioxovalerate dehydrogenase 
                EC 1.2.1.27                      methylmalonate-semialdehyde dehydrogenase (CoA-acylating) 
                EC 1.2.1.28                      benzaldehyde dehydrogenase (NAD+) 
                EC 1.2.1.29                      aryl-aldehyde dehydrogenase 
                EC 1.2.1.30                      carboxylate reductase (NADP+) 
                EC 1.2.1.31                      L-aminoadipate-semialdehyde dehydrogenase 
                EC 1.2.1.32                      aminomuconate-semialdehyde dehydrogenase 
                EC 1.2.1.33                      (R)-dehydropantoate dehydrogenase 
                EC 1.2.1.34                      D-mannonate dehydrogenase (NAD(P)+). Now EC 1.1.1.131, mannuronate reductase 
                EC 1.2.1.35                      uronate dehydrogenase. Now EC 1.1.1.203, uronate dehydrogenase 
                EC 1.2.1.36                      retinal dehydrogenase 
                EC 1.2.1.37                      xanthine dehydrogenase. Now EC 1.17.1.4, xanthine dehydrogenase 
                EC 1.2.1.38                      N-acetyl-γ-glutamyl-phosphate reductase 
                EC 1.2.1.39                      phenylacetaldehyde dehydrogenase 
                EC 1.2.1.40                      3α,7α,12α-trihydroxycholestan-26-al 26-oxidoreductase. The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase 
                EC 1.2.1.41                      glutamate-5-semialdehyde dehydrogenase 
                EC 1.2.1.42                      hexadecanal dehydrogenase (acylating) 
                EC 1.2.1.43                      formate dehydrogenase (NADP+). Now EC 1.17.1.10, formate dehydrogenase (NADP+) 
                EC 1.2.1.44                      cinnamoyl-CoA reductase 
                EC 1.2.1.45                      4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase. Now EC 1.1.1.312, 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase. 
                EC 1.2.1.46                      formaldehyde dehydrogenase 
                EC 1.2.1.47                      4-trimethylammoniobutyraldehyde dehydrogenase 
                EC 1.2.1.48                      long-chain-aldehyde dehydrogenase 
                EC 1.2.1.49                      2-oxoaldehyde dehydrogenase (NADP+) 
                EC 1.2.1.50                      long-chain acyl-protein thioester reductase 
                EC 1.2.1.51                      pyruvate dehydrogenase (NADP+) 
                EC 1.2.1.52                      oxoglutarate dehydrogenase (NADP+) 
                EC 1.2.1.53                      4-hydroxyphenylacetaldehyde dehydrogenase 
                EC 1.2.1.54                      γ-guanidinobutyraldehyde dehydrogenase 
                EC 1.2.1.55                      (R)-3-hydroxyacid ester dehydrogenase. Now EC 1.1.1.279, (R)-3-hydroxyacid-ester dehydrogenase 
                EC 1.2.1.56                      (S)-3-hydroxyacid ester dehydrogenase. Now EC 1.1.1.280, (S)-3-hydroxyacid-ester dehydrogenase 
                EC 1.2.1.57                      butanal dehydrogenase 
                EC 1.2.1.58                      phenylglyoxylate dehydrogenase (acylating) 
                EC 1.2.1.59                      glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) 
                EC 1.2.1.60                      5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase 
                EC 1.2.1.61                      4-hydroxymuconic-semialdehyde dehydrogenase 
                EC 1.2.1.62                      4-formylbenzenesulfonate dehydrogenase 
                EC 1.2.1.63                      6-oxohexanoate dehydrogenase 
                EC 1.2.1.64                      4-hydroxybenzaldehyde dehydrogenase (NAD+) 
                EC 1.2.1.65                      salicylaldehyde dehydrogenase 
                EC 1.2.1.66                      mycothiol-dependent formaldehyde dehydrogenase. Now EC 1.1.1.306, S-(hydroxymethyl)mycothiol dehydrogenase 
                EC 1.2.1.67                      vanillin dehydrogenase 
                EC 1.2.1.68                      coniferyl-aldehyde dehydrogenase 
                EC 1.2.1.69                      fluoroacetaldehyde dehydrogenase 
                EC 1.2.1.70                      glutamyl-tRNA reductase 
                EC 1.2.1.71                      succinylglutamate-semialdehyde dehydrogenase 
                EC 1.2.1.72                      erythrose-4-phosphate dehydrogenase 
                EC 1.2.1.73                      sulfoacetaldehyde dehydrogenase 
                EC 1.2.1.74                      abieta-7,13-dien-18-al dehydrogenase 
                EC 1.2.1.75                      malonyl-CoA reductase (malonate semialdehyde-forming) 
                EC 1.2.1.76                      succinate-semialdehyde dehydrogenase (acylating) 
                EC 1.2.1.77                      3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) 
                EC 1.2.1.78                      2-formylbenzoate dehydrogenase 
                EC 1.2.1.79                      succinate-semialdehyde dehydrogenase (NADP+) 
                EC 1.2.1.80                      long-chain acyl-[acyl-carrier-protein] reductase 
                EC 1.2.1.81                      sulfoacetaldehyde dehydrogenase (acylating) 
                EC 1.2.1.82                      β-apo-4′-carotenal dehydrogenase 
                EC 1.2.1.83                      3-succinoylsemialdehyde-pyridine dehydrogenase 
                EC 1.2.1.84                      alcohol-forming fatty acyl-CoA reductase 
                EC 1.2.1.85                      2-hydroxymuconate-6-semialdehyde dehydrogenase 
                EC 1.2.1.86                      geranial dehydrogenase 
                EC 1.2.1.87                      propanal dehydrogenase (CoA-propanoylating) 
                EC 1.2.1.88                      L-glutamate γ-semialdehyde dehydrogenase 
                EC 1.2.1.89                      D-glyceraldehyde dehydrogenase (NADP+) 
                EC 1.2.1.90                      glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] 
                EC 1.2.1.91                      3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase 
                EC 1.2.1.92                      3,6-anhydro-α-L-galactose dehydrogenase 
                EC 1.2.1.93                      formate dehydrogenase (NAD+, ferredoxin). Now EC 1.17.1.11, formate dehydrogenase (NAD+, ferredoxin) 
                EC 1.2.1.94                      farnesal dehydrogenase 
                EC 1.2.1.95                      L-2-aminoadipate reductase 
                EC 1.2.1.96                      4-hydroxybenzaldehyde dehydrogenase (NADP+) 
                EC 1.2.1.97                      3-sulfolactaldehyde dehydrogenase 
                EC 1.2.1.98                      2-hydroxy-2-methylpropanal dehydrogenase 
                EC 1.2.1.99                      4-(γ-glutamylamino)butanal dehydrogenase 
                EC 1.2.1.100                      5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase 
                EC 1.2.1.101                      L-tyrosine reductase 
                EC 1.2.1.102                      isopyridoxal dehydrogenase (5-pyridoxate-forming) 
                EC 1.2.1.103                      [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase 
                EC 1.2.1.104                      pyruvate dehydrogenase system 
                EC 1.2.1.105                      2-oxoglutarate dehydrogenase system 
                EC 1.2.1.106                      [amino-group carrier protein]-5-phospho-L-glutamate reductase 
                EC 1.2.1.107                      glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) 
        EC 1.2.2       []    With a cytochrome as acceptor 
                EC 1.2.2.1                      formate dehydrogenase (cytochrome) 
                EC 1.2.2.2                      pyruvate dehydrogenase (cytochrome). Now covered by EC 1.2.5.1, pyruvate dehydrogenase (quinone) 
                EC 1.2.2.3                      formate dehydrogenase (cytochrome-c-553). Now EC 1.17.2.3, formate dehydrogenase (cytochrome-c-553) 
                EC 1.2.2.4                      carbon-monoxide dehydrogenase (cytochrome b-561). Now classified as EC 1.2.5.3, aerobic carbon monoxide dehydrogenase 
        EC 1.2.3       []    With oxygen as acceptor 
                EC 1.2.3.1                      aldehyde oxidase 
                EC 1.2.3.2                      xanthine oxidase. Now EC 1.17.3.2, xanthine oxidase 
                EC 1.2.3.3                      pyruvate oxidase 
                EC 1.2.3.4                      oxalate oxidase 
                EC 1.2.3.5                      glyoxylate oxidase 
                EC 1.2.3.6                      pyruvate oxidase (CoA-acetylating) 
                EC 1.2.3.7                      indole-3-acetaldehyde oxidase 
                EC 1.2.3.8                      pyridoxal oxidase 
                EC 1.2.3.9                      aryl-aldehyde oxidase 
                EC 1.2.3.10                      carbon-monoxide oxidase. Activity due to EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561) 
                EC 1.2.3.11                      retinal oxidase. Now included with EC 1.2.3.1, aldehyde oxidase 
                EC 1.2.3.12                      vanillate demethylase. Now EC 1.14.13.82, vanillate monooxygenase 
                EC 1.2.3.13                      4-hydroxyphenylpyruvate oxidase 
                EC 1.2.3.14                      abscisic-aldehyde oxidase 
                EC 1.2.3.15                      (methyl)glyoxal oxidase 
        EC 1.2.4       []    With a disulfide as acceptor 
                EC 1.2.4.1                      pyruvate dehydrogenase (acetyl-transferring) 
                EC 1.2.4.2                      oxoglutarate dehydrogenase (succinyl-transferring) 
                EC 1.2.4.3                       2-oxoisocaproate dehydrogenase. Now included with EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) 
                EC 1.2.4.4                      3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) 
        EC 1.2.5       []    With a quinone or similar compound as acceptor 
                EC 1.2.5.1                      pyruvate dehydrogenase (quinone) 
                EC 1.2.5.2                      aldehyde dehydrogenase (quinone) 
                EC 1.2.5.3                      aerobic carbon monoxide dehydrogenase 
        EC 1.2.7       []    With an iron-sulfur protein as acceptor 
                EC 1.2.7.1                      pyruvate synthase 
                EC 1.2.7.2                      2-oxobutyrate synthase. Now included with EC 1.2.7.1, pyruvate synthase. 
                EC 1.2.7.3                      2-oxoglutarate synthase 
                EC 1.2.7.4                      anaerobic carbon monoxide dehydrogenase 
                EC 1.2.7.5                      aldehyde ferredoxin oxidoreductase 
                EC 1.2.7.6                      glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) 
                EC 1.2.7.7                      3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) 
                EC 1.2.7.8                      indolepyruvate ferredoxin oxidoreductase 
                EC 1.2.7.9                      2-oxoglutarate ferredoxin oxidoreductase. This enzyme is identical to EC 1.2.7.3, 2-oxoglutarate synthase 
                EC 1.2.7.10                      oxalate oxidoreductase 
                EC 1.2.7.11                      2-oxoacid oxidoreductase (ferredoxin) 
                EC 1.2.7.12                      formylmethanofuran dehydrogenase 
        EC 1.2.98       []    With other, known, physiological acceptors 
                EC 1.2.98.1                      formaldehyde dismutase 
        EC 1.2.99       []    With unknown physiological acceptors 
                EC 1.2.99.1                      uracil dehydrogenase. Now EC 1.17.99.4, uracil/thymine dehydrogenase 
                EC 1.2.99.2                      carbon-monoxide dehydrogenase (acceptor). Now EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin)  
                EC 1.2.99.3                      aldehyde dehydrogenase (pyrroloquinoline-quinone). Now EC 1.2.5.2, aldehyde dehydrogenase (quinone) 
                EC 1.2.99.4                      formaldehyde dismutase. Now EC 1.2.98.1, formaldehyde dismutase. 
                EC 1.2.99.5                      formylmethanofuran dehydrogenase. Now EC 1.2.7.12, formylmethanofuran dehydrogenase 
                EC 1.2.99.6                      carboxylate reductase 
                EC 1.2.99.7                      aldehyde dehydrogenase (FAD-independent) 
                EC 1.2.99.8                      glyceraldehyde dehydrogenase (FAD-containing)  
                EC 1.2.99.9                      formate dehydrogenase (coenzyme F420). Now EC 1.17.98.3, formate dehydrogenase (coenzyme F420) 
                EC 1.2.99.10                      4,4′-diapolycopenoate synthase 
    EC 1.3  [+]      
        EC 1.3.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.3.1.1                      dihydropyrimidine dehydrogenase (NAD+) 
                EC 1.3.1.2                      dihydropyrimidine dehydrogenase (NADP+) 
                EC 1.3.1.3                      Δ4-3-oxosteroid 5β-reductase 
                EC 1.3.1.4                      EC 1.3.1.4, cortisone α-reductase, transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP+) 
                EC 1.3.1.5                      cucurbitacin Δ23-reductase 
                EC 1.3.1.6                      fumarate reductase (NADH) 
                EC 1.3.1.7                      meso-tartrate dehydrogenase 
                EC 1.3.1.8                      acyl-CoA dehydrogenase (NADP+) 
                EC 1.3.1.9                      enoyl-[acyl-carrier-protein] reductase (NADH) 
                EC 1.3.1.10                      enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) 
                EC 1.3.1.11                      2-coumarate reductase 
                EC 1.3.1.12                      prephenate dehydrogenase 
                EC 1.3.1.13                      prephenate dehydrogenase (NADP+) 
                EC 1.3.1.14                      dihydroorotate dehydrogenase (NAD+) 
                EC 1.3.1.15                      dihydroorotate dehydrogenase (NADP+) 
                EC 1.3.1.16                      β-nitroacrylate reductase 
                EC 1.3.1.17                      3-methyleneoxindole reductase 
                EC 1.3.1.18                      kynurenate-7,8-dihydrodiol dehydrogenase 
                EC 1.3.1.19                      cis-1,2-dihydrobenzene-1,2-diol dehydrogenase 
                EC 1.3.1.20                      trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 
                EC 1.3.1.21                      7-dehydrocholesterol reductase 
                EC 1.3.1.22                      3-oxo-5α-steroid 4-dehydrogenase (NADP+) 
                EC 1.3.1.23                       cholestenone β-reductase. The enzyme is identical to EC 1.3.1.3, Δ4-3-oxosteroid 5β-reductase 
                EC 1.3.1.24                      biliverdin reductase 
                EC 1.3.1.25                      1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase 
                EC 1.3.1.26                      dihydrodipicolinate reductase. Now EC 1.17.1.8, 4-hydroxy-tetrahydrodipicolinate reductase. 
                EC 1.3.1.27                      2-hexadecenal reductase 
                EC 1.3.1.28                      2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 
                EC 1.3.1.29                      cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase 
                EC 1.3.1.30                      EC 1.3.1.30, progesterone 5α-reductase, transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP+). 
                EC 1.3.1.31                      2-enoate reductase 
                EC 1.3.1.32                      maleylacetate reductase 
                EC 1.3.1.33                      protochlorophyllide reductase 
                EC 1.3.1.34                      2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing] 
                EC 1.3.1.35                      phosphatidylcholine desaturase. Now EC 1.14.19.22, microsomal oleoyl-lipid 12-desaturase 
                EC 1.3.1.36                      geissoschizine dehydrogenase 
                EC 1.3.1.37                      cis-2-enoyl-CoA reductase (NADPH) 
                EC 1.3.1.38                      trans-2-enoyl-CoA reductase (NADPH) 
                EC 1.3.1.39                      enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) 
                EC 1.3.1.40                      2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase 
                EC 1.3.1.41                      xanthommatin reductase 
                EC 1.3.1.42                      12-oxophytodienoate reductase 
                EC 1.3.1.43                      arogenate dehydrogenase 
                EC 1.3.1.44                      trans-2-enoyl-CoA reductase (NAD+) 
                EC 1.3.1.45                      2′-hydroxyisoflavone reductase 
                EC 1.3.1.46                      biochanin-A reductase 
                EC 1.3.1.47                      α-santonin 1,2-reductase 
                EC 1.3.1.48                      13,14-dehydro-15-oxoprostaglandin 13-reductase 
                EC 1.3.1.49                      cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase 
                EC 1.3.1.50                       tetrahydroxynaphthalene reductase. Now EC 1.1.1.252 tetrahydroxynaphthalene reductase 
                EC 1.3.1.51                      2′-hydroxydaidzein reductase 
                EC 1.3.1.52                      2-methyl-branched-chain-enoyl-CoA reductase. Now EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase 
                EC 1.3.1.53                      (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase 
                EC 1.3.1.54                      precorrin-6A reductase 
                EC 1.3.1.55                       cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase. Enzyme is identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase 
                EC 1.3.1.56                      cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase 
                EC 1.3.1.57                      phloroglucinol reductase 
                EC 1.3.1.58                      2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase 
                EC 1.3.1.59                      1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase. No evidence in the paper cited that the enzyme exists 
                EC 1.3.1.60                      dibenzothiophene dihydrodiol dehydrogenase 
                EC 1.3.1.61                      terephthalate 1,2-cis-dihydrodiol dehydrogenase. Enzyme is identical to EC 1.3.1.53, (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase 
                EC 1.3.1.62                      pimeloyl-CoA dehydrogenase 
                EC 1.3.1.63                      2,4-dichlorobenzoyl-CoA reductase. Now EC 1.21.1.2, 2,4-dichlorobenzoyl-CoA reductase 
                EC 1.3.1.64                      phthalate 4,5-cis-dihydrodiol dehydrogenase 
                EC 1.3.1.65                      5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase 
                EC 1.3.1.66                      cis-dihydroethylcatechol dehydrogenase 
                EC 1.3.1.67                      cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase 
                EC 1.3.1.68                      1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase 
                EC 1.3.1.69                      zeatin reductase 
                EC 1.3.1.70                      Δ14-sterol reductase 
                EC 1.3.1.71                      Δ24(241)-sterol reductase 
                EC 1.3.1.72                      Δ24-sterol reductase 
                EC 1.3.1.73                      1,2-dihydrovomilenine reductase 
                EC 1.3.1.74                      2-alkenal reductase [NAD(P)+] 
                EC 1.3.1.75                      3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) 
                EC 1.3.1.76                      precorrin-2 dehydrogenase 
                EC 1.3.1.77                      anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming] 
                EC 1.3.1.78                      arogenate dehydrogenase (NADP+) 
                EC 1.3.1.79                      arogenate dehydrogenase [NAD(P)+] 
                EC 1.3.1.80                      red chlorophyll catabolite reductase. Now classified as EC 1.3.7.12, red chlorophyll catabolite reductase 
                EC 1.3.1.81                      (+)-pulegone reductase 
                EC 1.3.1.82                      (-)-isopiperitenone reductase 
                EC 1.3.1.83                      geranylgeranyl diphosphate reductase 
                EC 1.3.1.84                      acrylyl-CoA reductase (NADPH) 
                EC 1.3.1.85                      crotonyl-CoA carboxylase/reductase 
                EC 1.3.1.86                      crotonyl-CoA reductase 
                EC 1.3.1.87                      3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase 
                EC 1.3.1.88                      tRNA-dihydrouridine16/17 synthase [NAD(P)+] 
                EC 1.3.1.89                      tRNA-dihydrouridine47 synthase [NAD(P)+] 
                EC 1.3.1.90                      tRNA-dihydrouridine20a/20b synthase [NAD(P)+] 
                EC 1.3.1.91                      tRNA-dihydrouridine20 synthase [NAD(P)+] 
                EC 1.3.1.92                      artemisinic aldehyde Δ11(13)-reductase 
                EC 1.3.1.93                      very-long-chain enoyl-CoA reductase 
                EC 1.3.1.94                      polyprenol reductase 
                EC 1.3.1.95                      acrylyl-CoA reductase (NADH) 
                EC 1.3.1.96                      Botryococcus squalene synthase 
                EC 1.3.1.97                      botryococcene synthase 
                EC 1.3.1.98                      UDP-N-acetylmuramate dehydrogenase 
                EC 1.3.1.99                      iridoid synthase. Now known to be catalyzed by two different enzymes, EC 1.3.1.122, (S)-8-oxocitronellyl enol synthase, and EC 5.5.1.34, (+)-cis,trans-nepetalactol synthase 
                EC 1.3.1.100                      chanoclavine-I aldehyde reductase 
                EC 1.3.1.101                      2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] 
                EC 1.3.1.102                      2-alkenal reductase (NADP+) 
                EC 1.3.1.103                      2-haloacrylate reductase 
                EC 1.3.1.104                      enoyl-[acyl-carrier-protein] reductase (NADPH) 
                EC 1.3.1.105                      2-methylene-furan-3-one reductase 
                EC 1.3.1.106                      cobalt-precorrin-6A reductase 
                EC 1.3.1.107                      sanguinarine reductase 
                EC 1.3.1.108                      caffeoyl-CoA reductase 
                EC 1.3.1.109                      butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) 
                EC 1.3.1.110                      lactate dehydrogenase (NAD+, ferredoxin). Now EC 1.1.1.436, lactate dehydrogenase (NAD+,ferredoxin) 
                EC 1.3.1.111                      geranylgeranyl-bacteriochlorophyllide a reductase 
                EC 1.3.1.112                      anthocyanidin reductase [(2S)-flavan-3-ol-forming] 
                EC 1.3.1.113                      (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase 
                EC 1.3.1.114                      3-dehydro-bile acid Δ4,6-reductase 
                EC 1.3.1.115                      3-oxocholoyl-CoA 4-desaturase 
                EC 1.3.1.116                      7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase 
                EC 1.3.1.117                      hydroxycinnamoyl-CoA reductase 
                EC 1.3.1.118                      meromycolic acid enoyl-[acyl-carrier-protein] reductase 
                EC 1.3.1.119                      chlorobenzene dihydrodiol dehydrogenase 
                EC 1.3.1.120                      cyclohexane-1-carbonyl-CoA reductase (NADP+) 
                EC 1.3.1.121                      4-amino-4-deoxyprephenate dehydrogenase 
                EC 1.3.1.122                      (S)-8-oxocitronellyl enol synthase 
                EC 1.3.1.123                      8-oxogeranial reductase 
                EC 1.3.1.124                      2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] 
                EC 1.3.1.125                      acrylate reductase 
                EC 1.3.1.126                      2-epi-5-epi-valiolone dehydrogenase 
        EC 1.3.2       []    With a cytochrome as acceptor 
                EC 1.3.2.1                      butyryl-CoA dehydrogenase. Now EC 1.3.99.2, butyryl-CoA dehydrogenase 
                EC 1.3.2.2                      acyl-CoA dehydrogenase. Now EC 1.3.99.3, acyl-CoA dehydrogenase 
                EC 1.3.2.3                      L-galactonolactone dehydrogenase 
                EC 1.3.2.4                      fumarate reductase (cytochrome) 
        EC 1.3.3       []    With oxygen as acceptor 
                EC 1.3.3.1                      dihydroorotate oxidase. Now EC 1.3.98.1 [dihydroorotate dehydrogenase (fumarate)] 
                EC 1.3.3.2                      now EC 1.14.21.6, lathosterol oxidase. NAD(P)H had not been included previously, so enzyme had to be reclassified 
                EC 1.3.3.3                      coproporphyrinogen oxidase 
                EC 1.3.3.4                      protoporphyrinogen oxidase 
                EC 1.3.3.5                      bilirubin oxidase 
                EC 1.3.3.6                      acyl-CoA oxidase 
                EC 1.3.3.7                      dihydrouracil oxidase 
                EC 1.3.3.8                      tetrahydroberberine oxidase 
                EC 1.3.3.9                      secologanin synthase. Now EC 1.14.19.62, secologanin synthase 
                EC 1.3.3.10                      tryptophan α,β-oxidase 
                EC 1.3.3.11                      pyrroloquinoline-quinone synthase 
                EC 1.3.3.12                      L-galactonolactone oxidase 
                EC 1.3.3.13                      albonoursin synthase 
                EC 1.3.3.14                      aclacinomycin-A oxidase 
                EC 1.3.3.15                      coproporphyrinogen III oxidase (coproporphyrin-forming) 
                EC 1.3.3.16                      oxazoline dehydrogenase 
                EC 1.3.3.17                      benzylmalonyl-CoA dehydrogenase 
        EC 1.3.4       []    With a disulfide as acceptor 
                EC 1.3.4.1                      fumarate reductase (CoM/CoB) 
        EC 1.3.5       []    With a quinone or related compound as acceptor 
                EC 1.3.5.1                      succinate dehydrogenase 
                EC 1.3.5.2                      dihydroorotate dehydrogenase (quinone) 
                EC 1.3.5.3                      protoporphyrinogen IX dehydrogenase (quinone) 
                EC 1.3.5.4                      fumarate reductase (quinol), now included in EC 1.3.5.1, succinate dehydrogenase. 
                EC 1.3.5.5                      15-cis-phytoene desaturase 
                EC 1.3.5.6                      9,9′-dicis-ζ-carotene desaturase 
        EC 1.3.7       []    With an iron-sulfur protein as acceptor 
                EC 1.3.7.1                      6-hydroxynicotinate reductase 
                EC 1.3.7.2                      15,16-dihydrobiliverdin:ferredoxin oxidoreductase 
                EC 1.3.7.3                      phycoerythrobilin:ferredoxin oxidoreductase 
                EC 1.3.7.4                      phytochromobilin:ferredoxin oxidoreductase 
                EC 1.3.7.5                      phycocyanobilin:ferredoxin oxidoreductase 
                EC 1.3.7.6                      phycoerythrobilin synthase 
                EC 1.3.7.7                      ferredoxin:protochlorophyllide reductase (ATP-dependent) 
                EC 1.3.7.8                      benzoyl-CoA reductase 
                EC 1.3.7.9                      4-hydroxybenzoyl-CoA reductase. Now classified as EC 1.1.7.1, 4-hydroxybenzoyl-CoA reductase. 
                EC 1.3.7.10                      pentalenolactone synthase. Now EC 1.14.19.8, pentalenolactone synthase 
                EC 1.3.7.11                      2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase 
                EC 1.3.7.12                      red chlorophyll catabolite reductase 
                EC 1.3.7.13                      3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin) 
                EC 1.3.7.14                      3,8-divinyl chlorophyllide a reductase 
                EC 1.3.7.15                      chlorophyllide a reductase 
        EC 1.3.8       []    With a flavin as acceptor 
                EC 1.3.8.1                      short-chain acyl-CoA dehydrogenase 
                EC 1.3.8.2                      4,4′-diapophytoene desaturase (4,4′-diapolycopene-forming) 
                EC 1.3.8.3                      (R)-benzylsuccinyl-CoA dehydrogenase 
                EC 1.3.8.4                      isovaleryl-CoA dehydrogenase 
                EC 1.3.8.5                      short-chain 2-methylacyl-CoA dehydrogenase 
                EC 1.3.8.6                      glutaryl-CoA dehydrogenase (ETF) 
                EC 1.3.8.7                      medium-chain acyl-CoA dehydrogenase 
                EC 1.3.8.8                      long-chain acyl-CoA dehydrogenase 
                EC 1.3.8.9                      very-long-chain acyl-CoA dehydrogenase 
                EC 1.3.8.10                      cyclohex-1-ene-1-carbonyl-CoA dehydrogenase 
                EC 1.3.8.11                      cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein) 
                EC 1.3.8.12                      (2S)-methylsuccinyl-CoA dehydrogenase 
                EC 1.3.8.13                      crotonobetainyl-CoA reductase 
                EC 1.3.8.14                      L-prolyl-[peptidyl-carrier protein] dehydrogenase 
                EC 1.3.8.15                      3-(aryl)acrylate reductase 
                EC 1.3.8.16                      2-amino-4-deoxychorismate dehydrogenase 
                EC 1.3.8.17                      dehydro coenzyme F420 reductase 
        EC 1.3.98       []    With other, known, physiological acceptors 
                EC 1.3.98.1                      dihydroorotate dehydrogenase (fumarate) 
                EC 1.3.98.2                      fumarate reductase (CoM/CoB). Now EC 1.3.4.1, fumarate reductase (CoM/CoB) 
                EC 1.3.98.3                      coproporphyrinogen dehydrogenase 
                EC 1.3.98.4                      5a,11a-dehydrotetracycline reductase 
                EC 1.3.98.5                      hydrogen peroxide-dependent heme synthase 
                EC 1.3.98.6                      AdoMet-dependent heme synthase 
                EC 1.3.98.7                      [mycofactocin precursor peptide]-tyrosine decarboxylase 
        EC 1.3.99       []    With unknown physiological acceptors 
                EC 1.3.99.1                      succinate dehydrogenase. The activity is included in EC 1.3.5.1, succinate dehydrogenase (quinone). 
                EC 1.3.99.2                      butyryl-CoA dehydrogenase. Now EC 1.3.8.1, butyryl-CoA dehydrogenase. 
                EC 1.3.99.3                      acyl-CoA dehydrogenase, now EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase 
                EC 1.3.99.4                      3-oxosteroid 1-dehydrogenase 
                EC 1.3.99.5                      3-oxo-5α-steroid 4-dehydrogenase (acceptor) 
                EC 1.3.99.6                      3-oxo-5β-steroid 4-dehydrogenase 
                EC 1.3.99.7                      glutaryl-CoA dehydrogenase. Now EC 1.3.8.6, glutaryl-CoA dehydrogenase 
                EC 1.3.99.8                      2-furoyl-CoA dehydrogenase 
                EC 1.3.99.9                      β-cyclopiazonate dehydrogenase. Now EC 1.21.99.1, β-cyclopiazonate dehydrogenase 
                EC 1.3.99.10                      isovaleryl-CoA dehydrogenase. Now EC 1.3.8.4, isovaleryl-CoA dehydrogenase 
                EC 1.3.99.11                      dihydroorotate dehydrogenase. As the acceptor is now known, the enzyme has been transferred to EC 1.3.5.2, dihydroorotate dehydrogenase 
                EC 1.3.99.12                      2-methylacyl-CoA dehydrogenase. Now classified as EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase. 
                EC 1.3.99.13                      long-chain-acyl-CoA dehydrogenase. Now EC 1.3.8.8, long-chain-acyl-CoA dehydrogenase 
                EC 1.3.99.14                      cyclohexanone dehydrogenase 
                EC 1.3.99.15                      benzoyl-CoA reductase. Now EC 1.3.7.8. 
                EC 1.3.99.16                      isoquinoline 1-oxidoreductase 
                EC 1.3.99.17                      quinoline 2-oxidoreductase 
                EC 1.3.99.18                      quinaldate 4-oxidoreductase 
                EC 1.3.99.19                      quinoline-4-carboxylate 2-oxidoreductase 
                EC 1.3.99.20                      EC 1.3.99.20, 4-hydroxybenzoyl-CoA reductase. Now EC 1.3.7.9, 4-hydroxybenzoyl-CoA reductase. 
                EC 1.3.99.21                      (R)-benzylsuccinyl-CoA dehydrogenase. Now EC 1.3.8.3, (R)-benzylsuccinyl-CoA dehydrogenase 
                EC 1.3.99.22                      coproporphyrinogen dehydrogenase. Now EC 1.3.98.3, coproporphyrinogen dehydrogenase 
                EC 1.3.99.23                      all-trans-retinol 13,14-reductase 
                EC 1.3.99.24                      2-amino-4-deoxychorismate dehydrogenase. Now EC 1.3.8.16, 2-amino-4-deoxychorismate dehydrogenase 
                EC 1.3.99.25                      carvone reductase 
                EC 1.3.99.26                      all-trans-ζ-carotene desaturase 
                EC 1.3.99.27                      1-hydroxycarotenoid 3,4-desaturase 
                EC 1.3.99.28                      phytoene desaturase (neurosporene-forming) 
                EC 1.3.99.29                      phytoene desaturase (ζ-carotene-forming) 
                EC 1.3.99.30                      phytoene desaturase (3,4-didehydrolycopene-forming) 
                EC 1.3.99.31                      phytoene desaturase (lycopene-forming) 
                EC 1.3.99.32                      glutaryl-CoA dehydrogenase (acceptor) 
                EC 1.3.99.33                      urocanate reductase 
                EC 1.3.99.34                      2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (donor). Now classified as EC 1.3.7.11, 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase. 
                EC 1.3.99.35                      chlorophyllide a reductase. Now EC 1.3.7.15, chlorophyllide a reductase 
                EC 1.3.99.36                      cypemycin cysteine dehydrogenase (decarboxylating) 
                EC 1.3.99.37                      1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase 
                EC 1.3.99.38                      menaquinone-9 β-reductase 
                EC 1.3.99.39                      carotenoid φ-ring synthase 
                EC 1.3.99.40                      carotenoid χ-ring synthase 
                EC 1.3.99.41                      3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase 
    EC 1.4  [+]      
        EC 1.4.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.4.1.1                      alanine dehydrogenase 
                EC 1.4.1.2                      glutamate dehydrogenase 
                EC 1.4.1.3                      glutamate dehydrogenase [NAD(P)+] 
                EC 1.4.1.4                      glutamate dehydrogenase (NADP+) 
                EC 1.4.1.5                      L-amino-acid dehydrogenase 
                EC 1.4.1.6                      D-proline reductase. Now included with EC 1.21.4.1, D-proline reductase (dithiol) 
                EC 1.4.1.7                      serine 2-dehydrogenase 
                EC 1.4.1.8                      valine dehydrogenase (NADP+) 
                EC 1.4.1.9                      leucine dehydrogenase 
                EC 1.4.1.10                      glycine dehydrogenase 
                EC 1.4.1.11                      L-erythro-3,5-diaminohexanoate dehydrogenase 
                EC 1.4.1.12                      2,4-diaminopentanoate dehydrogenase 
                EC 1.4.1.13                      glutamate synthase (NADPH) 
                EC 1.4.1.14                      glutamate synthase (NADH) 
                EC 1.4.1.15                      lysine dehydrogenase 
                EC 1.4.1.16                      diaminopimelate dehydrogenase 
                EC 1.4.1.17                      N-methylalanine dehydrogenase 
                EC 1.4.1.18                      lysine 6-dehydrogenase 
                EC 1.4.1.19                      tryptophan dehydrogenase 
                EC 1.4.1.20                      phenylalanine dehydrogenase 
                EC 1.4.1.21                      aspartate dehydrogenase 
                EC 1.4.1.22                      ornithine cyclodeaminase. It was pointed out during the public-review process that there is no overall consumption of NAD+ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official 
                EC 1.4.1.23                      valine dehydrogenase (NAD+) 
                EC 1.4.1.24                      3-dehydroquinate synthase II 
                EC 1.4.1.25                      L-arginine dehydrogenase 
                EC 1.4.1.26                      2,4-diaminopentanoate dehydrogenase (NAD+) 
                EC 1.4.1.27                      glycine cleavage system 
                EC 1.4.1.28                      secondary-alkyl amine dehydrogenase [NAD(P)+] 
        EC 1.4.2       []    With a cytochrome as acceptor 
                EC 1.4.2.1                      glycine dehydrogenase (cytochrome) 
                EC 1.4.2.2                      nicotine dehydrogenase 
                EC 1.4.2.3                      pseudooxynicotine dehydrogenase 
        EC 1.4.3       []    With oxygen as acceptor 
                EC 1.4.3.1                      D-aspartate oxidase 
                EC 1.4.3.2                      L-amino-acid oxidase 
                EC 1.4.3.3                      D-amino-acid oxidase 
                EC 1.4.3.4                      monoamine oxidase 
                EC 1.4.3.5                      pyridoxal 5′-phosphate synthase 
                EC 1.4.3.6                      amine oxidase (copper-containing). This was classified on the basis of cofactor content rather than reaction catalysed and is now known to contain two distinct enzyme activities. It has been replaced by two enzymes, EC 1.4.3.21 (primary-amine oxidase) and EC 1.4.3.22 (diamine oxidase) 
                EC 1.4.3.7                      D-glutamate oxidase 
                EC 1.4.3.8                      ethanolamine oxidase 
                EC 1.4.3.9                       tyramine oxidase. Now included with EC 1.4.3.4 amine oxidase (flavin-containing) 
                EC 1.4.3.10                      putrescine oxidase 
                EC 1.4.3.11                      L-glutamate oxidase 
                EC 1.4.3.12                      cyclohexylamine oxidase 
                EC 1.4.3.13                      protein-lysine 6-oxidase 
                EC 1.4.3.14                      L-lysine oxidase 
                EC 1.4.3.15                      D-glutamate(D-aspartate) oxidase 
                EC 1.4.3.16                      L-aspartate oxidase 
                EC 1.4.3.17                      tryptophan α,β-oxidase. Now EC 1.3.3.10, tryptophan α,β-oxidase. Enzyme was incorrectly classified as acting on a CH-NH bond rather than a CH-CH bond 
                EC 1.4.3.18                      cytokinin oxidase. Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12, cytokinin dehydrogenase) 
                EC 1.4.3.19                      glycine oxidase 
                EC 1.4.3.20                      L-lysine 6-oxidase 
                EC 1.4.3.21                      primary-amine oxidase 
                EC 1.4.3.22                      diamine oxidase 
                EC 1.4.3.23                      7-chloro-L-tryptophan oxidase 
                EC 1.4.3.24                      pseudooxynicotine oxidase, now classified as EC 1.4.2.3, pseudooxynicotine dehydrogenase 
                EC 1.4.3.25                      L-arginine oxidase 
                EC 1.4.3.26                      pre-mycofactocin synthase 
                EC 1.4.3.27                      homospermidine oxidase 
        EC 1.4.4       []    With a disulfide as acceptor 
                EC 1.4.4.1                      D-proline reductase (dithiol). Now EC 1.21.4.1, D-proline reductase (dithiol) 
                EC 1.4.4.2                      glycine dehydrogenase (aminomethyl-transferring) 
        EC 1.4.5       []    With a quinone or other compound as acceptor 
                EC 1.4.5.1                      D-amino acid dehydrogenase (quinone) 
        EC 1.4.7       []    With an iron-sulfur protein as acceptor 
                EC 1.4.7.1                      glutamate synthase (ferredoxin) 
        EC 1.4.9       []    With a copper protein as acceptor 
                EC 1.4.9.1                      methylamine dehydrogenase (amicyanin) 
                EC 1.4.9.2                      aralkylamine dehydrogenase (azurin) 
        EC 1.4.99       []    With unknown physiological acceptors 
                EC 1.4.99.1                      D-amino-acid dehydrogenase. Now listed as EC 1.4.99.6, D-arginine dehydrogenase 
                EC 1.4.99.2                      taurine dehydrogenase 
                EC 1.4.99.3                      amine dehydrogenase. Now EC 1.4.9.1, methylamine dehydrogenase (amicyanin) 
                EC 1.4.99.4                      aralkylamine dehydrogenase. Now EC 1.4.9.2, aralkylamine dehydrogenase (azurin) 
                EC 1.4.99.5                      glycine dehydrogenase (cyanide-forming) 
                EC 1.4.99.6                      D-arginine dehydrogenase 
    EC 1.5  [+]      
        EC 1.5.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.5.1.1                      1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] 
                EC 1.5.1.2                      pyrroline-5-carboxylate reductase 
                EC 1.5.1.3                      dihydrofolate reductase 
                EC 1.5.1.4                       dihydrofolate dehydrogenase. Now included with EC 1.5.1.3 dihydrofolate reductase 
                EC 1.5.1.5                      methylenetetrahydrofolate dehydrogenase (NADP+) 
                EC 1.5.1.6                      formyltetrahydrofolate dehydrogenase 
                EC 1.5.1.7                      saccharopine dehydrogenase (NAD+, L-lysine-forming) 
                EC 1.5.1.8                      saccharopine dehydrogenase (NADP+, L-lysine-forming) 
                EC 1.5.1.9                      saccharopine dehydrogenase (NAD+, L-glutamate-forming) 
                EC 1.5.1.10                      saccharopine dehydrogenase (NADP+, L-glutamate-forming) 
                EC 1.5.1.11                      D-octopine dehydrogenase 
                EC 1.5.1.12                      1-pyrroline-5-carboxylate dehydrogenase. Now EC 1.2.1.88, L-glutamate γ-semialdehyde dehydrogenase.  
                EC 1.5.1.13                      nicotinate dehydrogenase. Now EC 1.17.1.5, nicotinate dehydrogenase. The enzyme was incorrectly classified as acting on a CH-NH group 
                EC 1.5.1.14                       1,2-didehydropipecolate reductase. Now included with EC 1.5.1.21 Δ1-piperideine-2-carboxylate reductase 
                EC 1.5.1.15                      methylenetetrahydrofolate dehydrogenase (NAD+) 
                EC 1.5.1.16                      D-lysopine dehydrogenase 
                EC 1.5.1.17                      alanopine dehydrogenase 
                EC 1.5.1.18                      ephedrine dehydrogenase 
                EC 1.5.1.19                      D-nopaline dehydrogenase 
                EC 1.5.1.20                      methylenetetrahydrofolate reductase [NAD(P)H] 
                EC 1.5.1.21                      1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) 
                EC 1.5.1.22                      strombine dehydrogenase 
                EC 1.5.1.23                      tauropine dehydrogenase 
                EC 1.5.1.24                      N5-(carboxyethyl)ornithine synthase 
                EC 1.5.1.25                      thiomorpholine-carboxylate dehydrogenase 
                EC 1.5.1.26                      β-alanopine dehydrogenase 
                EC 1.5.1.27                      1,2-dehydroreticulinium reductase (NADPH) 
                EC 1.5.1.28                      opine dehydrogenase 
                EC 1.5.1.29                      FMN reductase [NAD(P)H]. Now covered by EC 1.5.1.38 [FMN reductase (NADPH)], EC 1.5.1.39 [FMN reductase [NAD(P)H])] and EC 1.5.1.41 (riboflavin reductase [NAD(P)H]) 
                EC 1.5.1.30                      flavin reductase (NADPH) 
                EC 1.5.1.31                      berberine reductase 
                EC 1.5.1.32                      vomilenine reductase 
                EC 1.5.1.33                      pteridine reductase 
                EC 1.5.1.34                      6,7-dihydropteridine reductase 
                EC 1.5.1.35                      1-pyrroline dehydrogenase. The enzyme is identical to EC 1.2.1.19, aminobutyraldehyde dehydrogenase, as the substrates 1-pyrroline and 4-aminobutanal are interconvertible 
                EC 1.5.1.36                      flavin reductase (NADH) 
                EC 1.5.1.37                      FAD reductase (NADH) 
                EC 1.5.1.38                      FMN reductase (NADPH) 
                EC 1.5.1.39                      FMN reductase [NAD(P)H] 
                EC 1.5.1.40                      8-hydroxy-5-deazaflavin:NADPH oxidoreductase 
                EC 1.5.1.41                      riboflavin reductase [NAD(P)H] 
                EC 1.5.1.42                      FMN reductase (NADH) 
                EC 1.5.1.43                      carboxynorspermidine synthase 
                EC 1.5.1.44                      festuclavine dehydrogenase 
                EC 1.5.1.45                      FAD reductase [NAD(P)H] 
                EC 1.5.1.46                      agroclavine dehydrogenase 
                EC 1.5.1.47                      dihydromethanopterin reductase [NAD(P)+] 
                EC 1.5.1.48                      2-methyl-1-pyrroline reductase 
                EC 1.5.1.49                      1-pyrroline-2-carboxylate reductase [NAD(P)H] 
                EC 1.5.1.50                      dihydromonapterin reductase 
                EC 1.5.1.51                      N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase 
                EC 1.5.1.52                      staphylopine dehydrogenase 
                EC 1.5.1.53                      methylenetetrahydrofolate reductase (NADPH) 
                EC 1.5.1.54                      methylenetetrahydrofolate reductase (NADH) 
        EC 1.5.3       []    With oxygen as acceptor 
                EC 1.5.3.1                      sarcosine oxidase (formaldehyde-forming) 
                EC 1.5.3.2                      N-methyl-L-amino-acid oxidase 
                EC 1.5.3.3                       spermine oxidase 
                EC 1.5.3.4                      N6-methyl-lysine oxidase 
                EC 1.5.3.5                      (S)-6-hydroxynicotine oxidase 
                EC 1.5.3.6                      (R)-6-hydroxynicotine oxidase 
                EC 1.5.3.7                      L-pipecolate oxidase 
                EC 1.5.3.8                      (S)-tetrahydroprotoberberine oxidase. Now included with EC 1.3.3.8, tetrahydroberberine oxidase 
                EC 1.5.3.9                      reticuline oxidase. Now EC 1.21.3.3, reticuline oxidase 
                EC 1.5.3.10                      dimethylglycine oxidase 
                EC 1.5.3.11                      polyamine oxidase. Now included with EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (N8-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase) 
                EC 1.5.3.12                      dihydrobenzophenanthridine oxidase 
                EC 1.5.3.13                      N1-acetylpolyamine oxidase 
                EC 1.5.3.14                      polyamine oxidase (propane-1,3-diamine-forming) 
                EC 1.5.3.15                      N8-acetylspermidine oxidase (propane-1,3-diamine-forming) 
                EC 1.5.3.16                      spermine oxidase 
                EC 1.5.3.17                      non-specific polyamine oxidase 
                EC 1.5.3.18                      L-saccharopine oxidase 
                EC 1.5.3.19                      4-methylaminobutanoate oxidase (formaldehyde-forming) 
                EC 1.5.3.20                      N-alkylglycine oxidase 
                EC 1.5.3.21                      4-methylaminobutanoate oxidase (methylamine-forming) 
                EC 1.5.3.22                      coenzyme F420H2 oxidase  
                EC 1.5.3.23                      glyphosate oxidoreductase 
                EC 1.5.3.24                      sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) 
                EC 1.5.3.25                      fructosyl amine oxidase (glucosone-forming) 
                EC 1.5.3.26                      fructosyl amine oxidase (fructosamine-forming) 
        EC 1.5.4       []    With a disulfide as acceptor 
                EC 1.5.4.1                      pyrimidodiazepine synthase 
        EC 1.5.5       []    With a quinone or similar compound as acceptor 
                EC 1.5.5.1                      electron-transferring-flavoprotein dehydrogenase 
                EC 1.5.5.2                      proline dehydrogenase 
                EC 1.5.5.3                      hydroxyproline dehydrogenase 
        EC 1.5.7       []    With an iron-sulfur protein as acceptor 
                EC 1.5.7.1                      methylenetetrahydrofolate reductase (ferredoxin) 
                EC 1.5.7.2                      coenzyme F420 oxidoreductase (ferredoxin) 
                EC 1.5.7.3                      N,N-dimethylglycine/sarcosine dehydrogenase (ferredoxin) 
        EC 1.5.8       []    With a flavin or flavoprotein as acceptor 
                EC 1.5.8.1                      dimethylamine dehydrogenase 
                EC 1.5.8.2                      trimethylamine dehydrogenase 
                EC 1.5.8.3                      sarcosine dehydrogenase 
                EC 1.5.8.4                      dimethylglycine dehydrogenase 
        EC 1.5.98       []    With other, known, physiological acceptors 
                EC 1.5.98.1                      methylenetetrahydromethanopterin dehydrogenase 
                EC 1.5.98.2                      5,10-methylenetetrahydromethanopterin reductase 
                EC 1.5.98.3                      coenzyme F420:methanophenazine dehydrogenase 
        EC 1.5.99       []    With unknown physiological acceptors 
                EC 1.5.99.1                      sarcosine dehydrogenase. Now EC 1.5.8.3, sarcosine dehydrogenase 
                EC 1.5.99.2                      dimethylglycine dehydrogenase. Now EC 1.5.8.4, dimethylglycine dehydrogenase 
                EC 1.5.99.3                      L-pipecolate dehydrogenase 
                EC 1.5.99.4                      nicotine 6-hydroxylase 
                EC 1.5.99.5                      methylglutamate dehydrogenase 
                EC 1.5.99.6                      spermidine dehydrogenase 
                EC 1.5.99.7                      trimethylamine dehydrogenase. Now EC 1.5.8.2, trimethylamine dehydrogenase 
                EC 1.5.99.8                      proline dehydrogenase. Now EC 1.5.5.2, proline dehydrogenase.  
                EC 1.5.99.9                      methylenetetrahydromethanopterin dehydrogenase. As the acceptor is known the enzyme has been transferred to EC 1.5.98.1, methylenetetrahydromethanopterin dehydrogenase 
                EC 1.5.99.10                      dimethylamine dehydrogenase. Now EC 1.5.8.1, dimethylamine dehydrogenase 
                EC 1.5.99.11                      methylenetetrahydromethanopterin dehydrogenase. As the acceptor is known the enzyme has been transferred to EC 1.5.98.2, 5,10-methylenetetrahydromethanopterin reductase 
                EC 1.5.99.12                      cytokinin dehydrogenase 
                EC 1.5.99.13                      D-proline dehydrogenase 
                EC 1.5.99.14                      6-hydroxypseudooxynicotine dehydrogenase 
                EC 1.5.99.15                      dihydromethanopterin reductase (acceptor) 
    EC 1.6  [+]      
        EC 1.6.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.6.1.1                      NAD(P)+ transhydrogenase (Si-specific) 
                EC 1.6.1.2                      NAD(P)+ transhydrogenase (Re/Si-specific). Now classified as EC 7.1.1.1, proton-translocating NAD(P)+ transhydrogenase 
                EC 1.6.1.3                      NAD(P)+ transhydrogenase 
                EC 1.6.1.4                      NAD(P)+ transhydrogenase (ferredoxin) 
                EC 1.6.1.5                      proton-translocating NAD(P)+ transhydrogenase. Now EC 7.1.1.1, proton-translocating NAD(P)+ transhydrogenase 
        EC 1.6.2       []    With a heme protein as acceptor 
                EC 1.6.2.1                      NADH2 cytochrome c reductase. Now EC 1.6.99.3, NADH dehydrogenase 
                EC 1.6.2.2                      cytochrome-b5 reductase 
                EC 1.6.2.3                       cytochrome reductase (NADPH) 
                EC 1.6.2.4                      NADPH—hemoprotein reductase 
                EC 1.6.2.5                      NADPH—cytochrome-c2 reductase 
                EC 1.6.2.6                      leghemoglobin reductase 
        EC 1.6.3       []    With oxygen as acceptor 
                EC 1.6.3.1                      NAD(P)H oxidase (H2O2-forming) 
                EC 1.6.3.2                      NAD(P)H oxidase (H2O-forming) 
                EC 1.6.3.3                      NADH oxidase (H2O2-forming) 
                EC 1.6.3.4                      NADH oxidase (H2O-forming) 
                EC 1.6.3.5                      renalase 
        EC 1.6.4       []    With a disulfide as acceptor (deleted sub-subclass) 
                EC 1.6.4.1                      cystine reductase (NADH). Now EC 1.8.1.6, cystine reductase 
                EC 1.6.4.2                      glutathione reductase (NADPH). Now EC 1.8.1.7, glutathione-disulfide reductase 
                EC 1.6.4.3                      dihydrolipoamide reductase (NAD+). Now EC 1.8.1.4, dihydrolipoyl dehydrogenase 
                EC 1.6.4.4                      protein-disulfide reductase [NAD(P)H]. Now EC 1.8.1.8, protein-disulfide reductase 
                EC 1.6.4.5                      thioredoxin reductase (NADPH). Now EC 1.8.1.9, thioredoxin-disulfide reductase 
                EC 1.6.4.6                      CoA-glutathione reductase (NADPH). Now EC 1.8.1.10, CoA-glutathione reductase 
                EC 1.6.4.7                      asparagusate reductase (NADH). Now EC 1.8.1.11, asparagusate reductase 
                EC 1.6.4.8                      trypanothione reductase. Now EC 1.8.1.12, trypanothione-disulfide reductase 
                EC 1.6.4.9                      bis-γ-glutamylcystine reductase (NADPH). Now EC 1.8.1.13, bis-γ-glutamylcystine reductase 
                EC 1.6.4.10                      CoA-disulfide reductase (NADH). Now EC 1.8.1.14, CoA-disulfide reductase 
        EC 1.6.5       []    With a quinone or similar compound as acceptor 
                EC 1.6.5.1                       quinone reductase 
                EC 1.6.5.2                      NAD(P)H dehydrogenase (quinone) 
                EC 1.6.5.3                      NADH:ubiquinone reductase (H+-translocating). Now EC 7.1.1.2, NADH:ubiquinone reductase (H+-translocating) 
                EC 1.6.5.4                      monodehydroascorbate reductase (NADH) 
                EC 1.6.5.5                      NADPH:quinone reductase 
                EC 1.6.5.6                      p-benzoquinone reductase (NADPH) 
                EC 1.6.5.7                      2-hydroxy-1,4-benzoquinone reductase 
                EC 1.6.5.8                      NADH:ubiquinone reductase (Na+-transporting). Now EC 7.2.1.1, NADH:ubiquinone reductase (Na+-transporting) 
                EC 1.6.5.9                      NADH:quinone reductase (non-electrogenic) 
                EC 1.6.5.10                      NADPH dehydrogenase (quinone) 
                EC 1.6.5.11                      NADH dehydrogenase (quinone). Identical to EC 1.6.5.9, NADH:quinone reductase (non-electrogenic) 
                EC 1.6.5.12                      demethylphylloquinone reductase 
        EC 1.6.6       []    With a nitrogenous group as acceptor 
                EC 1.6.6.1                      nitrate reductase (NADH). Now EC 1.7.1.1, nitrate reductase (NADH) 
                EC 1.6.6.2                      nitrate reductase [NAD(P)H]. Now EC 1.7.1.2, nitrate reductase [NAD(P)H] 
                EC 1.6.6.3                      nitrate reductase (NADPH). Now EC 1.7.1.3, nitrate reductase (NADPH) 
                EC 1.6.6.4                      nitrite reductase [NAD(P)H]. Now EC 1.7.1.4, nitrite reductase [NAD(P)H] 
                EC 1.6.6.5                      now EC 1.7.2.1, nitrite reductase (NO-forming) 
                EC 1.6.6.6                      hyponitrite reductase. Now EC 1.7.1.5, hyponitrite reductase 
                EC 1.6.6.7                      azobenzene reductase. Now EC 1.7.1.6, azobenzene reductase 
                EC 1.6.6.8                      GMP reductase. Now EC 1.7.1.7, GMP reductase 
                EC 1.6.6.9                      The activity is now known to be catalysed by EC 1.7.2.3, trimethylamine-N-oxide reductase. 
                EC 1.6.6.10                      nitroquinoline-N-oxide reductase. Now EC 1.7.1.9, nitroquinoline-N-oxide reductase 
                EC 1.6.6.11                      hydroxylamine reductase (NADH). Now EC 1.7.1.10, hydroxylamine reductase (NADH) 
                EC 1.6.6.12                      4-(dimethylamino)phenylazoxybenzene reductase. Now EC 1.7.1.11, 4-(dimethylamino)phenylazoxybenzene reductase 
                EC 1.6.6.13                      N-hydroxy-2-acetamidofluorene reductase. Now EC 1.7.1.12, N-hydroxy-2-acetamidofluorene reductase 
        EC 1.6.7       []    With an iron-sulfur protein as acceptor (deleted sub-subclass) 
                EC 1.6.7.1                      ferredoxin—NADP+ reductase. Now EC 1.18.1.2, ferredoxin—NADP+ reductase 
                EC 1.6.7.2                      rubredoxin—NAD+ reductase. Now EC 1.18.1.1, rubredoxin—NAD+ reductase 
                EC 1.6.7.3                      now EC 1.18.1.3, ferredoxin—NAD+ reductase 
        EC 1.6.8       []    With a flavin as acceptor (deleted sub-subclass) 
                EC 1.6.8.1                      NAD(P)H dehydrogenase (FMN). Now EC 1.5.1.29, FMN reductase 
                EC 1.6.8.2                      NADPH dehydrogenase (flavin). Now EC 1.5.1.30, flavin reductase 
        EC 1.6.99       []    With unknown physiological acceptors 
                EC 1.6.99.1                      NADPH dehydrogenase 
                EC 1.6.99.2                      NAD(P)H dehydrogenase (quinone). Now EC 1.6.5.2, NAD(P)H dehydrogenase (quinone). The enzyme was erroneously transferred from this sub-subclass in 1965 
                EC 1.6.99.3                      NADH dehydrogenase. The activity is covered by EC 7.1.1.2, NADH:ubiquinone reductase (H+-translocating) 
                EC 1.6.99.4                      nitrite reductase. Now EC 1.18.1.2, ferredoxin—NADP+ reductase 
                EC 1.6.99.5                      NADH dehydrogenase (quinone). Transferred to EC 1.6.5.11, NADH dehydrogenase (quinone) 
                EC 1.6.99.6                      NADPH dehydrogenase (quinone). Now EC 1.6.5.10, NADPH dehydrogenase (quinone) 
                EC 1.6.99.7                      dihydropteridine reductase. Now EC 1.5.1.34, 6,7-dihydropteridine reductase 
                EC 1.6.99.8                      aquacobalamin reductase. This entry has been deleted since no specific enzyme catalysing this activity has been identified and it has been shown that aquacobalamin is efficiently reduced by free dihydroflavins and by non-specific reduced flavoproteins. 
                EC 1.6.99.9                      cob(II)alamin reductase. Now EC 1.16.1.4, cob(II)alamin reductase 
                EC 1.6.99.10                      dihydropteridine reductase (NADH). Now included with EC 1.5.1.34, 6,7-dihydropteridine reductase 
                EC 1.6.99.11                      aquacobalamin reductase (NADPH). This entry has been deleted since the enzyme the entry was based on was later shown to be EC 1.2.1.51, pyruvate dehydrogenase (NADP+). On the other hand, it has been shown that non-enzymatic reduction of cob(III)alamin to cob(II)alamin occurs efficiently in the presence of free dihydroflavins or non-specific reduced flavoproteins. 
                EC 1.6.99.12                      cyanocobalamin reductase (NADPH, cyanide-eliminating). Now EC 1.16.1.6, cyanocobalamin reductase (cyanide-eliminating) 
                EC 1.6.99.13                      ferric-chelate reductase. Now EC 1.16.1.7, ferric-chelate reductase 
    EC 1.7  [+]      
        EC 1.7.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.7.1.1                      nitrate reductase (NADH) 
                EC 1.7.1.2                      nitrate reductase [NAD(P)H] 
                EC 1.7.1.3                      nitrate reductase (NADPH) 
                EC 1.7.1.4                      nitrite reductase [NAD(P)H] 
                EC 1.7.1.5                      hyponitrite reductase 
                EC 1.7.1.6                      azobenzene reductase 
                EC 1.7.1.7                      GMP reductase 
                EC 1.7.1.8                       withdrawn in the light of further information on the acceptor 
                EC 1.7.1.9                      nitroquinoline-N-oxide reductase 
                EC 1.7.1.10                      hydroxylamine reductase (NADH) 
                EC 1.7.1.11                      4-(dimethylamino)phenylazoxybenzene reductase 
                EC 1.7.1.12                      N-hydroxy-2-acetamidofluorene reductase 
                EC 1.7.1.13                      preQ1 synthase 
                EC 1.7.1.14                      nitric oxide reductase [NAD(P)+, nitrous oxide-forming] 
                EC 1.7.1.15                      nitrite reductase (NADH) 
                EC 1.7.1.16                      nitrobenzene nitroreductase 
                EC 1.7.1.17                      FMN-dependent NADH-azoreductase 
        EC 1.7.2       []    With a cytochrome as acceptor 
                EC 1.7.2.1                      nitrite reductase (NO-forming) 
                EC 1.7.2.2                      nitrite reductase (cytochrome; ammonia-forming) 
                EC 1.7.2.3                      trimethylamine-N-oxide reductase 
                EC 1.7.2.4                      nitrous-oxide reductase 
                EC 1.7.2.5                      nitric oxide reductase (cytochrome c) 
                EC 1.7.2.6                      hydroxylamine dehydrogenase 
                EC 1.7.2.7                      hydrazine synthase 
                EC 1.7.2.8                      hydrazine dehydrogenase 
                EC 1.7.2.9                      hydroxylamine oxidase 
        EC 1.7.3       []    With oxygen as acceptor 
                EC 1.7.3.1                      nitroalkane oxidase 
                EC 1.7.3.2                      acetylindoxyl oxidase 
                EC 1.7.3.3                      factor-independent urate hydroxylase 
                EC 1.7.3.4                      hydroxylamine oxidase. Now covered by EC 1.7.2.6, hydroxylamine dehydrogenase, and EC 1.7.3.6, hydroxylamine oxidase (cytochrome) 
                EC 1.7.3.5                      3-aci-nitropropanoate oxidase 
                EC 1.7.3.6                      hydroxylamine oxidase (cytochrome) 
        EC 1.7.5       []    With a quinone or similar compound as acceptor 
                EC 1.7.5.1                      nitrate reductase (quinone) 
                EC 1.7.5.2                      nitric oxide reductase (menaquinol) 
        EC 1.7.6       []    With a nitrogenous group as acceptor 
                EC 1.7.6.1                      nitrite dismutase 
        EC 1.7.7       []    With an iron-sulfur protein as acceptor 
                EC 1.7.7.1                      ferredoxin—nitrite reductase 
                EC 1.7.7.2                      ferredoxin—nitrate reductase 
        EC 1.7.9       []    With a copper protein as acceptor 
        EC 1.7.99       []    With unknown physiological acceptors 
                EC 1.7.99.1                      hydroxylamine reductase 
                EC 1.7.99.2                       nitric-oxide reductase. Reaction may have been due to the combined action of EC 1.7.99.6 nitrous-oxide reductase and EC 1.7.99.7 nitric-oxide reductase 
                EC 1.7.99.3                      nitrite reductase. Now included with EC 1.7.2.1, nitrite reductase (NO-forming) 
                EC 1.7.99.4                      nitrate reductase, Now EC 1.7.1.1, nitrate reductase (NADH), EC 1.7.1.2, nitrate reductase [NAD(P)H], EC 1.7.1.3, nitrate reductase (NADPH), EC 1.7.5.1, nitrate reductase (quinone), EC 1.7.7.2, nitrate reductase (ferredoxin) and EC 1.9.6.1, nitrate reductase (cytochrome) 
                EC 1.7.99.5                       5,10-methylenetetrahydrofolate reductase (FADH2). Now included with EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]. Based on the reference, it had been thought that this was a separate enzyme from EC 1.5.1.20 but the reference upon which the entry was based has since been disproved 
                EC 1.7.99.6                      EC 1.7.99.6, nitrous-oxide reductase. Now EC 1.7.2.4. 
                EC 1.7.99.7                      nitric-oxide reductase. Now EC 1.7.2.5 nitric oxide reductase (cytochrome c) 
                EC 1.7.99.8                      hydrazine oxidoreductase. Now classified as EC 1.7.2.8, hydrazine dehydrogenase. 
    EC 1.8  [+]      
        EC 1.8.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.8.1.1                       cysteamine dehydrogenase 
                EC 1.8.1.2                      assimilatory sulfite reductase (NADPH) 
                EC 1.8.1.3                      hypotaurine dehydrogenase. The reaction is now known to be catalyzed by EC 1.14.13.8, flavin-containing monooxygenase. 
                EC 1.8.1.4                      dihydrolipoyl dehydrogenase 
                EC 1.8.1.5                      2-oxopropyl-CoM reductase (carboxylating) 
                EC 1.8.1.6                      cystine reductase 
                EC 1.8.1.7                      glutathione-disulfide reductase 
                EC 1.8.1.8                      protein-disulfide reductase 
                EC 1.8.1.9                      thioredoxin-disulfide reductase 
                EC 1.8.1.10                      CoA-glutathione reductase 
                EC 1.8.1.11                      asparagusate reductase 
                EC 1.8.1.12                      trypanothione-disulfide reductase 
                EC 1.8.1.13                      bis-γ-glutamylcystine reductase 
                EC 1.8.1.14                      CoA-disulfide reductase 
                EC 1.8.1.15                      mycothione reductase 
                EC 1.8.1.16                      glutathione amide reductase 
                EC 1.8.1.17                      dimethylsulfone reductase 
                EC 1.8.1.18                      NAD(P)H sulfur oxidoreductase (CoA-dependent) 
                EC 1.8.1.19                      sulfide dehydrogenase 
                EC 1.8.1.20                      4,4′-dithiodibutanoate disulfide reductase 
                EC 1.8.1.21                      dissimilatory dimethyldisulfide reductase 
                EC 1.8.1.22                      dissimilatory sulfite reductase system 
        EC 1.8.2       []    With a cytochrome as acceptor 
                EC 1.8.2.1                      sulfite dehydrogenase (cytochrome) 
                EC 1.8.2.2                      thiosulfate dehydrogenase 
                EC 1.8.2.3                      sulfide-cytochrome-c reductase (flavocytochrome c) 
                EC 1.8.2.4                      dimethyl sulfide:cytochrome c2 reductase 
                EC 1.8.2.5                      thiosulfate reductase (cytochrome) 
                EC 1.8.2.6                      S-disulfanyl-L-cysteine oxidoreductase 
                EC 1.8.2.7                      thiocyanate desulfurase 
        EC 1.8.3       []    With oxygen as acceptor 
                EC 1.8.3.1                      sulfite oxidase 
                EC 1.8.3.2                      thiol oxidase 
                EC 1.8.3.3                      glutathione oxidase 
                EC 1.8.3.4                      methanethiol oxidase 
                EC 1.8.3.5                      prenylcysteine oxidase 
                EC 1.8.3.6                      farnesylcysteine lyase 
                EC 1.8.3.7                      formylglycine-generating enzyme 
        EC 1.8.4       []    With a disulfide as acceptor 
                EC 1.8.4.1                      glutathione—homocystine transhydrogenase 
                EC 1.8.4.2                      protein-disulfide reductase (glutathione) 
                EC 1.8.4.3                      glutathione—CoA-glutathione transhydrogenase 
                EC 1.8.4.4                      glutathione—cystine transhydrogenase 
                EC 1.8.4.5                      methionine-S-oxide reductase. Now EC 1.8.4.13, L-methionine (S)-S-oxide reductase and EC 1.8.4.14, L-methionine (R)-S-oxide reductase 
                EC 1.8.4.6                      protein-methionine-S-oxide reductase. Proved to be due to EC 1.8.4.11, peptide-methionine (S)-S-oxide reductase 
                EC 1.8.4.7                      enzyme-thiol transhydrogenase (glutathione-disulfide) 
                EC 1.8.4.8                      phosphoadenylyl-sulfate reductase (thioredoxin) 
                EC 1.8.4.9                      adenylyl-sulfate reductase (glutathione) 
                EC 1.8.4.10                      adenylyl-sulfate reductase (thioredoxin) 
                EC 1.8.4.11                      peptide-methionine (S)-S-oxide reductase 
                EC 1.8.4.12                      peptide-methionine (R)-S-oxide reductase 
                EC 1.8.4.13                      L-methionine (S)-S-oxide reductase 
                EC 1.8.4.14                      L-methionine (R)-S-oxide reductase 
                EC 1.8.4.15                      protein dithiol oxidoreductase (disulfide-forming) 
                EC 1.8.4.16                      thioredoxin:protein disulfide reductase 
        EC 1.8.5       []    With a quinone or similar compound as acceptor 
                EC 1.8.5.1                      glutathione dehydrogenase (ascorbate) 
                EC 1.8.5.2                      thiosulfate dehydrogenase (quinone) 
                EC 1.8.5.3                      respiratory dimethylsulfoxide reductase 
                EC 1.8.5.4                      bacterial sulfide:quinone reductase 
                EC 1.8.5.5                      thiosulfate reductase (quinone) 
                EC 1.8.5.6                      sulfite dehydrogenase (quinone) 
                EC 1.8.5.7                      glutathionyl-hydroquinone reductase 
                EC 1.8.5.8                      eukaryotic sulfide quinone oxidoreductase 
                EC 1.8.5.9                      protein dithiol:quinone oxidoreductase DsbB 
                EC 1.8.5.10                      [DsrC]-trisulfide reductase 
        EC 1.8.6       []    With a nitrogenous group as acceptor (deleted sub-subclass) 
                EC 1.8.6.1                       Nitrate-ester reductase. Now included with EC 2.5.1.18 glutathione transferase 
        EC 1.8.7       []    With an iron-sulfur protein as acceptor 
                EC 1.8.7.1                      assimilatory sulfite reductase (ferredoxin) 
                EC 1.8.7.2                      ferredoxin:thioredoxin reductase 
                EC 1.8.7.3                      ferredoxin:CoB-CoM heterodisulfide reductase 
        EC 1.8.98       []    With other, known, physiological acceptors 
                EC 1.8.98.1                      dihydromethanophenazine:CoB-CoM heterodisulfide reductase 
                EC 1.8.98.2                      sulfiredoxin 
                EC 1.8.98.3                      sulfite reductase (coenzyme F420) 
                EC 1.8.98.4                      coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase 
                EC 1.8.98.5                      H2:CoB-CoM heterodisulfide,ferredoxin reductase 
                EC 1.8.98.6                      formate:CoB-CoM heterodisulfide,ferredoxin reductase 
                EC 1.8.98.7                      cysteine-type anaerobic sulfatase-maturating enzyme 
        EC 1.8.99       []    With unknown physiological acceptors 
                EC 1.8.99.1                      sulfite reductase. Now covered by EC 1.8.1.2, assimilatory sulfite reductase (NADPH) and EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin).  
                EC 1.8.99.2                      adenylyl-sulfate reductase 
                EC 1.8.99.3                      hydrogensulfite reductase, now known to be an in vitro artifact of EC 1.8.99.5, dissimilatory sulfite reductase 
                EC 1.8.99.4                      phosphoadenosine-phosphosulfate reductase. Now EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin) 
                EC 1.8.99.5                      dissimilatory sulfite reductase. Now classified as EC 1.8.1.22, dissimilatory sulfite reductase system. 
    EC 1.9  [+]      
        EC 1.9.3       []    With oxygen as acceptor 
                EC 1.9.3.1                      cytochrome-c oxidase. Now EC 7.1.1.9, cytochrome-c oxidase 
                EC 1.9.3.2                      Pseudomonas cytochrome oxidase. Now included with EC 1.7.2.1, nitrite reductase (NO-forming) 
        EC 1.9.6       []    With a nitrogenous group as acceptor 
                EC 1.9.6.1                      nitrate reductase (cytochrome) 
        EC 1.9.98       []    With other, known, physiological acceptors 
                EC 1.9.98.1                      iron—cytochrome-c reductase 
        EC 1.9.99       []    With unknown physiological acceptors 
                EC 1.9.99.1                      iron—cytochrome-c reductase. Now EC 1.9.98.1, iron—cytochrome-c reductase 
    EC 1.10  [+]      
        EC 1.10.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.10.1.1                      trans-acenaphthene-1,2-diol dehydrogenase 
        EC 1.10.2       []    With a cytochrome as acceptor 
                EC 1.10.2.1                      L-ascorbate—cytochrome-b5 reductase. The activity is covered by EC 7.2.1.3, ascorbate ferrireductase (transmembrane) 
                EC 1.10.2.2                      quinol—cytochrome-c reductase. Now EC 7.1.1.8, quinol—cytochrome-c reductase 
        EC 1.10.3       []    With oxygen as acceptor 
                EC 1.10.3.1                      catechol oxidase 
                EC 1.10.3.2                      laccase 
                EC 1.10.3.3                      L-ascorbate oxidase 
                EC 1.10.3.4                      o-aminophenol oxidase 
                EC 1.10.3.5                      3-hydroxyanthranilate oxidase 
                EC 1.10.3.6                      rifamycin-B oxidase 
                EC 1.10.3.7                      sulochrin oxidase [(+)-bisdechlorogeodin-forming]. Now EC 1.21.3.4, sulochrin oxidase [(+)-bisdechlorogeodin-forming] 
                EC 1.10.3.8                      sulochrin oxidase [(+)-bisdechlorogeodin-forming]. Now EC 1.21.3.5, sulochrin oxidase [(-)-bisdechlorogeodin-forming] 
                EC 1.10.3.9                      photosystem II 
                EC 1.10.3.10                      ubiquinol oxidase (H+-transporting). Now EC 7.1.1.3, ubiquinol oxidase (H+-transporting) 
                EC 1.10.3.11                      ubiquinol oxidase (non-electrogenic) 
                EC 1.10.3.12                      menaquinol oxidase (H+-transporting). Now EC 7.1.1.5, menaquinol oxidase (H+-transporting) 
                EC 1.10.3.13                      caldariellaquinol oxidase (H+-transporting). Now EC 7.1.1.4, caldariellaquinol oxidase (H+-transporting) 
                EC 1.10.3.14                      ubiquinol oxidase (electrogenic, non H+-transporting). Now EC 7.1.1.7, ubiquinol oxidase (electrogenic, proton-motive force generating) 
                EC 1.10.3.15                      grixazone synthase 
                EC 1.10.3.16                      dihydrophenazinedicarboxylate synthase 
                EC 1.10.3.17                      superoxide oxidase 
        EC 1.10.5       []    With a quinone or related compound as acceptor 
                EC 1.10.5.1                      ribosyldihydronicotinamide dehydrogenase (quinone) 
        EC 1.10.9       []    With a copper protein as acceptor 
                EC 1.10.9.1                      plastoquinol—plastocyanin reductase. Now EC 7.1.1.6, plastoquinol—plastocyanin reductase 
        EC 1.10.99       []    With unknown physiological acceptors 
                EC 1.10.99.1                      Now EC 1.10.9.1 plastoquinol—plastocyanin reductase 
                EC 1.10.99.2                      ribosyldihydronicotinamide dehydrogenase (quinone). Now classified as EC 1.10.5.1, ribosyldihydronicotinamide dehydrogenase (quinone). 
                EC 1.10.99.3                      violaxanthin de-epoxidase. Now classified as EC 1.23.5.1, violaxanthin de-epoxidase. 
    EC 1.11  [+]      
        EC 1.11.1       []      
                EC 1.11.1.1                      NADH peroxidase 
                EC 1.11.1.2                      NADPH peroxidase 
                EC 1.11.1.3                      fatty-acid peroxidase 
                EC 1.11.1.4                      now EC 1.13.11.11 tryptophan 2,3-dioxygenase 
                EC 1.11.1.5                      cytochrome-c peroxidase 
                EC 1.11.1.6                      catalase 
                EC 1.11.1.7                      peroxidase 
                EC 1.11.1.8                      iodide peroxidase 
                EC 1.11.1.9                      glutathione peroxidase 
                EC 1.11.1.10                      chloride peroxidase 
                EC 1.11.1.11                      L-ascorbate peroxidase 
                EC 1.11.1.12                      phospholipid-hydroperoxide glutathione peroxidase 
                EC 1.11.1.13                      manganese peroxidase 
                EC 1.11.1.14                      lignin peroxidase 
                EC 1.11.1.15                      peroxiredoxin. Now described by EC 1.11.1.24, thioredoxin-dependent peroxiredoxin; EC 1.11.1.25, glutaredoxin-dependent peroxiredoxin; EC 1.11.1.26, NADH-dependent peroxiredoxin; EC 1.11.1.27, glutathione-dependent peroxiredoxin; EC 1.11.1.28, lipoyl-dependent peroxiredoxin; and EC 1.11.1.29, mycoredoxin-dependent peroxiredoxin. 
                EC 1.11.1.16                      versatile peroxidase 
                EC 1.11.1.17                      glutathione amide-dependent peroxidase 
                EC 1.11.1.18                      bromide peroxidase 
                EC 1.11.1.19                      dye decolorizing peroxidase 
                EC 1.11.1.20                      prostamide/prostaglandin F synthase 
                EC 1.11.1.21                      catalase-peroxidase 
                EC 1.11.1.22                      hydroperoxy fatty acid reductase 
                EC 1.11.1.23                      (S)-2-hydroxypropylphosphonic acid epoxidase 
                EC 1.11.1.24                      thioredoxin-dependent peroxiredoxin 
                EC 1.11.1.25                      glutaredoxin-dependent peroxiredoxin 
                EC 1.11.1.26                      NADH-dependent peroxiredoxin 
                EC 1.11.1.27                      glutathione-dependent peroxiredoxin 
                EC 1.11.1.28                      lipoyl-dependent peroxiredoxin 
                EC 1.11.1.29                      mycoredoxin-dependent peroxiredoxin 
        EC 1.11.2       []      
                EC 1.11.2.1                      unspecific peroxygenase 
                EC 1.11.2.2                      myeloperoxidase 
                EC 1.11.2.3                      plant seed peroxygenase 
                EC 1.11.2.4                      fatty-acid peroxygenase 
                EC 1.11.2.5                      3-methyl-L-tyrosine peroxygenase 
                EC 1.11.2.6                      L-tyrosine peroxygenase 
    EC 1.12  [+]      
        EC 1.12.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.12.1.1                      peroxidase. Now EC 1.12.7.2, ferredoxin hydrogenase 
                EC 1.12.1.2                      hydrogen dehydrogenase 
                EC 1.12.1.3                      hydrogen dehydrogenase (NADP+) 
                EC 1.12.1.4                      hydrogenase (NAD+, ferredoxin) 
                EC 1.12.1.5                      hydrogen dehydrogenase [NAD(P)+] 
        EC 1.12.2       []    With a cytochrome as acceptor 
                EC 1.12.2.1                      cytochrome-c3 hydrogenase 
        EC 1.12.5       []    With a quinone or similar compound as acceptor 
                EC 1.12.5.1                      hydrogen:quinone oxidoreductase 
        EC 1.12.7       []    With an iron-sulfur protein as acceptor 
                EC 1.12.7.1                      ferredoxin hydrogenase. Now EC 1.12.7.2, ferredoxin hydrogenase 
                EC 1.12.7.2                      ferredoxin hydrogenase 
        EC 1.12.98       []    With other, known, physiological acceptors 
                EC 1.12.98.1                      coenzyme F420 hydrogenase 
                EC 1.12.98.2                      5,10-methenyltetrahydromethanopterin hydrogenase 
                EC 1.12.98.3                      Methanosarcina-phenazine hydrogenase 
                EC 1.12.98.4                      sulfhydrogenase 
        EC 1.12.99       []    With unknown physiological acceptors 
                EC 1.12.99.1                      coenzyme F420 hydrogenase. Now EC 1.12.98.1, coenzyme F420 hydrogenase 
                EC 1.12.99.2                       coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase. Now shown to be two enzymes, EC 1.12.98.3, Methanosarcina-phenazine hydrogenase and EC 1.8.98.1, CoB—CoM heterodisulfide reductase 
                EC 1.12.99.3                      hydrogen:quinone oxidoreductase. Now EC 1.12.5.1, hydrogen:quinone oxidoreductase 
                EC 1.12.99.4                      N5,N10-methenyltetrahydromethanopterin hydrogenase. Now EC 1.12.98.2, 5,10-methenyltetrahydromethanopterin hydrogenase 
                EC 1.12.99.5                       3,4-dihydroxyquinoline 2,4-dioxygenase. Identical to EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase 
                EC 1.12.99.6                      hydrogenase (acceptor) 
    EC 1.13  [+]      
        EC 1.13.11       []    With incorporation of two atoms of oxygen 
                EC 1.13.11.1                      catechol 1,2-dioxygenase 
                EC 1.13.11.2                      catechol 2,3-dioxygenase 
                EC 1.13.11.3                      protocatechuate 3,4-dioxygenase 
                EC 1.13.11.4                      gentisate 1,2-dioxygenase 
                EC 1.13.11.5                      homogentisate 1,2-dioxygenase 
                EC 1.13.11.6                      3-hydroxyanthranilate 3,4-dioxygenase 
                EC 1.13.11.7                       3,4-dihydroxyphenylacetate 3,4-dioxygenase 
                EC 1.13.11.8                      protocatechuate 4,5-dioxygenase 
                EC 1.13.11.9                      2,5-dihydroxypyridine 5,6-dioxygenase 
                EC 1.13.11.10                      7,8-dihydroxykynurenate 8,8a-dioxygenase 
                EC 1.13.11.11                      tryptophan 2,3-dioxygenase 
                EC 1.13.11.12                      linoleate 13S-lipoxygenase 
                EC 1.13.11.13                      ascorbate 2,3-dioxygenase. The activity is the sum of several enzymatic and spontaneous reactions 
                EC 1.13.11.14                      2,3-dihydroxybenzoate 3,4-dioxygenase 
                EC 1.13.11.15                      3,4-dihydroxyphenylacetate 2,3-dioxygenase 
                EC 1.13.11.16                      3-carboxyethylcatechol 2,3-dioxygenase 
                EC 1.13.11.17                      indole 2,3-dioxygenase 
                EC 1.13.11.18                      persulfide dioxygenase 
                EC 1.13.11.19                      cysteamine dioxygenase 
                EC 1.13.11.20                      cysteine dioxygenase 
                EC 1.13.11.21                      β-carotene 15,15′-dioxygenase. Now EC 1.14.99.36, β-carotene 15,15′-monooxygenase 
                EC 1.13.11.22                      caffeate 3,4-dioxygenase 
                EC 1.13.11.23                      2,3-dihydroxyindole 2,3-dioxygenase 
                EC 1.13.11.24                      quercetin 2,3-dioxygenase 
                EC 1.13.11.25                      3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase 
                EC 1.13.11.26                      peptide-tryptophan 2,3-dioxygenase 
                EC 1.13.11.27                      4-hydroxyphenylpyruvate dioxygenase 
                EC 1.13.11.28                      2,3-dihydroxybenzoate 2,3-dioxygenase 
                EC 1.13.11.29                      stizolobate synthase 
                EC 1.13.11.30                      stizolobinate synthase 
                EC 1.13.11.31                      arachidonate 12-lipoxygenase 
                EC 1.13.11.32                      2-nitropropane dioxygenase. Now EC 1.13.12.16, nitronate monooxygenase 
                EC 1.13.11.33                      arachidonate 15-lipoxygenase 
                EC 1.13.11.34                      arachidonate 5-lipoxygenase 
                EC 1.13.11.35                      pyrogallol 1,2-oxygenase 
                EC 1.13.11.36                      chloridazon-catechol dioxygenase 
                EC 1.13.11.37                      hydroxyquinol 1,2-dioxygenase 
                EC 1.13.11.38                      1-hydroxy-2-naphthoate 1,2-dioxygenase 
                EC 1.13.11.39                      biphenyl-2,3-diol 1,2-dioxygenase 
                EC 1.13.11.40                      arachidonate 8-lipoxygenase 
                EC 1.13.11.41                      2,4′-dihydroxyacetophenone dioxygenase 
                EC 1.13.11.42                       indoleamine-pyrrole 2,3-dioxygenase. The enzyme was identical to EC 1.13.11.11, tryptophan 2,3-dioxygenase 
                EC 1.13.11.43                      lignostilbene αβ-dioxygenase 
                EC 1.13.11.44                      linoleate diol synthase. Activity is covered by EC 1.13.11.60, linoleate 8R-lipoxygenase and EC 5.4.4.6, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase. 
                EC 1.13.11.45                      linoleate 11-lipoxygenase 
                EC 1.13.11.46                      4-hydroxymandelate synthase 
                EC 1.13.11.47                      3-hydroxy-4-oxoquinoline 2,4-dioxygenase 
                EC 1.13.11.48                      3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase 
                EC 1.13.11.49                      chlorite O2-lyase 
                EC 1.13.11.50                      acetylacetone-cleaving enzyme 
                EC 1.13.11.51                      9-cis-epoxycarotenoid dioxygenase 
                EC 1.13.11.52                      indoleamine 2,3-dioxygenase 
                EC 1.13.11.53                      acireductone dioxygenase (Ni2+-requiring) 
                EC 1.13.11.54                      acireductone dioxygenase [iron(II)-requiring] 
                EC 1.13.11.55                      sulfur oxygenase/reductase 
                EC 1.13.11.56                      1,2-dihydroxynaphthalene dioxygenase 
                EC 1.13.11.57                      gallate dioxygenase 
                EC 1.13.11.58                      linoleate 9S-lipoxygenase 
                EC 1.13.11.59                      torulene dioxygenase 
                EC 1.13.11.60                      linoleate 8R-lipoxygenase 
                EC 1.13.11.61                      linolenate 9R-lipoxygenase 
                EC 1.13.11.62                      linoleate 10R-lipoxygenase 
                EC 1.13.11.63                      β-carotene 15,15′-dioxygenase 
                EC 1.13.11.64                      5-nitrosalicylate dioxygenase 
                EC 1.13.11.65                      carotenoid isomerooxygenase 
                EC 1.13.11.66                      hydroquinone 1,2-dioxygenase 
                EC 1.13.11.67                      8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase 
                EC 1.13.11.68                      9-cis-β-carotene 9′,10′-cleaving dioxygenase 
                EC 1.13.11.69                      carlactone synthase 
                EC 1.13.11.70                      all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase 
                EC 1.13.11.71                      carotenoid-9′,10′-cleaving dioxygenase 
                EC 1.13.11.72                      2-hydroxyethylphosphonate dioxygenase 
                EC 1.13.11.73                      methylphosphonate synthase 
                EC 1.13.11.74                      2-aminophenol 1,6-dioxygenase 
                EC 1.13.11.75                      all-trans-8′-apo-β-carotenal 15,15′-oxygenase 
                EC 1.13.11.76                      2-amino-5-chlorophenol 1,6-dioxygenase 
                EC 1.13.11.77                      oleate 10S-lipoxygenase 
                EC 1.13.11.78                      2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) 
                EC 1.13.11.79                      aerobic 5,6-dimethylbenzimidazole synthase 
                EC 1.13.11.80                      (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase 
                EC 1.13.11.81                      7,8-dihydroneopterin oxygenase 
                EC 1.13.11.82                      8′-apo-carotenoid 13,14-cleaving dioxygenase 
                EC 1.13.11.83                      4-hydroxy-3-prenylphenylpyruvate oxygenase 
                EC 1.13.11.84                      crocetin dialdehyde synthase 
                EC 1.13.11.85                      exo-cleaving rubber dioxygenase 
                EC 1.13.11.86                      5-aminosalicylate 1,2-dioxygenase 
                EC 1.13.11.87                      endo-cleaving rubber dioxygenase 
                EC 1.13.11.88                      isoeugenol monooxygenase 
                EC 1.13.11.89                      (hydroxymethyl)phosphonate dioxygenase 
                EC 1.13.11.90                      [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming) 
                EC 1.13.11.91                      3-mercaptopropionate dioxygenase 
                EC 1.13.11.92                      fatty acid α-dioxygenase 
                EC 1.13.11.93                      2-oxoadipate dioxygenase/decarboxylase 
        EC 1.13.12       []    With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) 
                EC 1.13.12.1                      arginine 2-monooxygenase 
                EC 1.13.12.2                      lysine 2-monooxygenase 
                EC 1.13.12.3                      tryptophan 2-monooxygenase 
                EC 1.13.12.4                      lactate 2-monooxygenase 
                EC 1.13.12.5                      Renilla-type luciferase 
                EC 1.13.12.6                      Cypridina-luciferin 2-monooxygenase 
                EC 1.13.12.7                      firefly luciferase 
                EC 1.13.12.8                      Watasenia-luciferin 2-monooxygenase 
                EC 1.13.12.9                      phenylalanine 2-monooxygenase 
                EC 1.13.12.10                       lysine 6-monooxygenase. Reaction covered by EC 1.14.13.59, L-lysine 6-monooxygenase (NADPH) 
                EC 1.13.12.11                      methylphenyltetrahydropyridine N-monooxygenase. The activity is due to EC 1.14.13.8, flavin-containing monooxygenase 
                EC 1.13.12.12                      apo-β-carotenoid-14′,13′-dioxygenase. The enzyme was misclassified and has been transferred to EC 1.13.11.67, 8-apo-β-carotenoid 14′,13′-cleaving dioxygenase 
                EC 1.13.12.13                      Oplophorus-luciferin 2-monooxygenase 
                EC 1.13.12.14                      chlorophyllide-a oxygenase. Now EC 1.14.13.122, chlorophyllide-a oxygenase 
                EC 1.13.12.15                      3,4-dihydroxyphenylalanine oxidative deaminase 
                EC 1.13.12.16                      nitronate monooxygenase 
                EC 1.13.12.17                      dichloroarcyriaflavin A synthase 
                EC 1.13.12.18                      dinoflagellate luciferase 
                EC 1.13.12.19                      2-oxoglutarate dioxygenase (ethene-forming) 
                EC 1.13.12.20                      noranthrone monooxygenase 
                EC 1.13.12.21                      tetracenomycin-F1 monooxygenase 
                EC 1.13.12.22                      deoxynogalonate monooxygenase 
                EC 1.13.12.23                      4-hydroxy-3-prenylbenzoate synthase 
                EC 1.13.12.24                      calcium-regulated photoprotein 
        EC 1.13.99       []    Miscellaneous 
                EC 1.13.99.1                      inositol oxygenase 
                EC 1.13.99.2                      benzoate 1,2-dioxygenase. Now EC 1.14.12.10, benzoate 1,2-dioxygenase 
                EC 1.13.99.3                      tryptophan 2′-dioxygenase 
                EC 1.13.99.4                      4-chlorophenylacetate 3,4-dioxygenase. Now EC 1.14.12.9, 4-chlorophenylacetate 3,4-dioxygenase 
                EC 1.13.99.5                      now EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase 
    EC 1.14  [+]      
        EC 1.14.1       []    With NADH or NADPH as one donor (deleted sub-subclass) 
                EC 1.14.1.1                      now EC 1.14.14.1, unspecific monooxygenase 
                EC 1.14.1.2                      now EC 1.14.13.9, kynurenine 3-monooxygenase 
                EC 1.14.1.3                      squalene hydroxylase. Activity is covered by EC 1.14.99.7, squalene monooxygenase and EC 5.4.99.7, lanosterol synthase 
                EC 1.14.1.4                      now EC 1.14.99.2, kynurenine 7,8-hydroxylase 
                EC 1.14.1.5                      now EC 1.14.13.5, imidazoleacetate 4-monooxygenase 
                EC 1.14.1.6                      now EC 1.14.15.4, steroid 11β-monooxygenase 
                EC 1.14.1.7                      now EC 1.14.99.9, steroid 17α-monooxygenase 
                EC 1.14.1.8                      now EC 1.14.99.10, steroid 21-monooxygenase 
                EC 1.14.1.9                       cholesterol 20-hydroxylase 
                EC 1.14.1.10                      now EC 1.14.99.11, estradiol 6β-monooxygenase 
                EC 1.14.1.11                      oestriol 2-hydroxylase 
        EC 1.14.2       []    With ascorbate as one donor (deleted sub-subclass) 
                EC 1.14.2.1                      now EC 1.14.17.1, dopamine β-monooxygenase 
                EC 1.14.2.2                      now EC 1.13.11.27, 4-hydroxyphenylpyruvate dioxygenase 
        EC 1.14.3       []    With reduced pteridine as one donor (deleted sub-subclass) 
                EC 1.14.3.1                      now EC 1.14.16.1, phenylalanine 4-monooxygenase 
        EC 1.14.11       []    With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor 
                EC 1.14.11.1                      γ-butyrobetaine dioxygenase 
                EC 1.14.11.2                      procollagen-proline 4-dioxygenase 
                EC 1.14.11.3                      pyrimidine-deoxynucleoside 2′-dioxygenase 
                EC 1.14.11.4                      procollagen-lysine 5-dioxygenase 
                EC 1.14.11.5                       5-hydroxymethyluracil,2-oxoglutarate dioxygenase. Now included with EC 1.14.11.6 thymine dioxygenase 
                EC 1.14.11.6                      thymine dioxygenase 
                EC 1.14.11.7                      procollagen-proline 3-dioxygenase 
                EC 1.14.11.8                      trimethyllysine dioxygenase 
                EC 1.14.11.9                      flavanone 3-dioxygenase 
                EC 1.14.11.10                      pyrimidine-deoxynucleoside 1′-dioxygenase 
                EC 1.14.11.11                      hyoscyamine (6S)-dioxygenase 
                EC 1.14.11.12                      gibberellin-44 dioxygenase 
                EC 1.14.11.13                      gibberellin 2β-dioxygenase 
                EC 1.14.11.14                      6β-hydroxyhyoscyamine epoxidase. Now EC 1.14.20.13, 6β-hydroxyhyoscyamine epoxidase 
                EC 1.14.11.15                      gibberellin 3β-dioxygenase 
                EC 1.14.11.16                      peptide-aspartate β-dioxygenase 
                EC 1.14.11.17                      taurine dioxygenase 
                EC 1.14.11.18                      phytanoyl-CoA dioxygenase 
                EC 1.14.11.19                      anthocyanidin synthase. Now EC 1.14.20.4, anthocyanidin synthase 
                EC 1.14.11.20                      deacetoxyvindoline 4-hydroxylase 
                EC 1.14.11.21                      clavaminate synthase 
                EC 1.14.11.22                      flavone synthase. Now EC 1.14.20.5, flavone synthase 
                EC 1.14.11.23                      flavonol synthase. Now EC 1.14.20.6, flavonol synthase 
                EC 1.14.11.24                      2′-deoxymugineic-acid 2′-dioxygenase 
                EC 1.14.11.25                      mugineic-acid 3-dioxygenase 
                EC 1.14.11.26                      deacetoxycephalosporin-C hydroxylase 
                EC 1.14.11.27                      [histone H3]-dimethyl-L-lysine36 demethylase 
                EC 1.14.11.28                      proline 3-hydroxylase 
                EC 1.14.11.29                      hypoxia-inducible factor-proline dioxygenase 
                EC 1.14.11.30                      hypoxia-inducible factor-asparagine dioxygenase 
                EC 1.14.11.31                      thebaine 6-O-demethylase 
                EC 1.14.11.32                      codeine 3-O-demethylase 
                EC 1.14.11.33                      DNA oxidative demethylase 
                EC 1.14.11.34                      2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming). Now EC 1.14.20.7, 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) 
                EC 1.14.11.35                      1-deoxypentalenic acid 11β-hydroxylase 
                EC 1.14.11.36                      pentalenolactone F synthase 
                EC 1.14.11.37                      kanamycin B dioxygenase 
                EC 1.14.11.38                      verruculogen synthase 
                EC 1.14.11.39                      L-asparagine hydroxylase 
                EC 1.14.11.40                      enduracididine β-hydroxylase 
                EC 1.14.11.41                      L-arginine hydroxylase 
                EC 1.14.11.42                      tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase  
                EC 1.14.11.43                      (S)-dichlorprop dioxygenase (2-oxoglutarate) 
                EC 1.14.11.44                      (R)-dichlorprop dioxygenase (2-oxoglutarate) 
                EC 1.14.11.45                      L-isoleucine 4-hydroxylase 
                EC 1.14.11.46                      2-aminoethylphosphonate dioxygenase 
                EC 1.14.11.47                      [50S ribosomal protein L16]-arginine 3-hydroxylase 
                EC 1.14.11.48                      xanthine dioxygenase 
                EC 1.14.11.49                      uridine-5′-phosphate dioxygenase 
                EC 1.14.11.50                      (–)-deoxypodophyllotoxin synthase. Now EC 1.14.20.8, (–)-deoxypodophyllotoxin synthase 
                EC 1.14.11.51                      DNA N6-methyladenine demethylase 
                EC 1.14.11.52                      validamycin A dioxygenase 
                EC 1.14.11.53                      mRNA N6-methyladenine demethylase 
                EC 1.14.11.54                      mRNA N1-methyladenine demethylase 
                EC 1.14.11.55                      ectoine hydroxylase 
                EC 1.14.11.56                      L-proline cis-4-hydroxylase 
                EC 1.14.11.57                      L-proline trans-4-hydroxylase 
                EC 1.14.11.58                      ornithine lipid ester-linked acyl 2-hydroxylase 
                EC 1.14.11.59                      2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase 
                EC 1.14.11.60                      scopoletin 8-hydroxylase 
                EC 1.14.11.61                      feruloyl-CoA 6-hydroxylase 
                EC 1.14.11.62                      trans-4-coumaroyl-CoA 2-hydroxylase 
                EC 1.14.11.63                      peptidyl-lysine (3S)-dioxygenase 
                EC 1.14.11.64                      glutarate dioxygenase 
                EC 1.14.11.65                      [histone H3]-dimethyl-L-lysine9 demethylase 
                EC 1.14.11.66                      [histone H3]-trimethyl-L-lysine9 demethylase 
                EC 1.14.11.67                      [histone H3]-trimethyl-L-lysine4 demethylase 
                EC 1.14.11.68                      [histone H3]-trimethyl-L-lysine27 demethylase 
                EC 1.14.11.69                      [histone H3]-trimethyl-L-lysine36 demethylase 
                EC 1.14.11.70                      7-deoxycylindrospermopsin hydroxylase 
                EC 1.14.11.71                      methylphosphonate hydroxylase 
                EC 1.14.11.72                      [2-(trimethylamino)ethyl]phosphonate dioxygenase 
                EC 1.14.11.73                      [protein]-arginine 3-hydroxylase 
                EC 1.14.11.74                      L-isoleucine 31-dioxygenase 
                EC 1.14.11.75                      31-hydroxy-L-isoleucine 4-dioxygenase 
                EC 1.14.11.76                      L-glutamate 3(R)-hydroxylase 
                EC 1.14.11.77                      alkyl sulfatase 
                EC 1.14.11.78                      (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase 
                EC 1.14.11.79                      protein-L-histidine (3S)-3-hydroxylase 
                EC 1.14.11.80                      methylcytosine dioxygenase 
                EC 1.14.11.81                      (–)-cyclopenine synthase 
                EC 1.14.11.82                      5-dehydro-6-demethoxyfumagillol dioxygenase 
        EC 1.14.12       []    With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor 
                EC 1.14.12.1                      anthranilate 1,2-dioxygenase (deaminating, decarboxylating) 
                EC 1.14.12.2                      now EC 1.14.13.35 anthranilate 3-monooxygenase (deaminating) 
                EC 1.14.12.3                      benzene 1,2-dioxygenase 
                EC 1.14.12.4                      3-hydroxy-2-methylpyridinecarboxylate dioxygenase. Now EC 1.14.13.242, 3-hydroxy-2-methylpyridinecarboxylate monooxygenase 
                EC 1.14.12.5                      5-pyridoxate dioxygenase. Now EC 1.14.13.241, 5-pyridoxate monooxygenase 
                EC 1.14.12.6                      2-hydroxycyclohexanone 2-monooxygenase. Now EC 1.14.13.66, 2-hydroxycyclohexanone 2-monooxygenase 
                EC 1.14.12.7                      phthalate 4,5-dioxygenase 
                EC 1.14.12.8                      4-sulfobenzoate 3,4-dioxygenase 
                EC 1.14.12.9                      4-chlorophenylacetate 3,4-dioxygenase 
                EC 1.14.12.10                      benzoate 1,2-dioxygenase 
                EC 1.14.12.11                      toluene dioxygenase 
                EC 1.14.12.12                      naphthalene 1,2-dioxygenase 
                EC 1.14.12.13                      2-halobenzoate 1,2-dioxygenase 
                EC 1.14.12.14                      2-aminobenzenesulfonate 2,3-dioxygenase 
                EC 1.14.12.15                      terephthalate 1,2-dioxygenase 
                EC 1.14.12.16                      2-hydroxyquinoline 5,6-dioxygenase 
                EC 1.14.12.17                      nitric oxide dioxygenase 
                EC 1.14.12.18                      biphenyl 2,3-dioxygenase 
                EC 1.14.12.19                      3-phenylpropanoate dioxygenase 
                EC 1.14.12.20                      pheophorbide a oxygenase. Now classified as EC 1.14.15.17, pheophorbide a oxygenase. 
                EC 1.14.12.21                      benzoyl-CoA 2,3-dioxygenase. Now EC 1.14.13.208, benzoyl-CoA 2,3-epoxidase 
                EC 1.14.12.22                      carbazole 1,9a-dioxygenase 
                EC 1.14.12.23                      nitroarene dioxygenase 
                EC 1.14.12.24                      2,4-dinitrotoluene dioxygenase 
                EC 1.14.12.25                      p-cumate 2,3-dioxygenase 
                EC 1.14.12.26                      chlorobenzene dioxygenase 
        EC 1.14.13       []    With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.13.1                      salicylate 1-monooxygenase 
                EC 1.14.13.2                      4-hydroxybenzoate 3-monooxygenase 
                EC 1.14.13.3                      4-hydroxyphenylacetate 3-monooxygenase. Now EC 1.14.14.9, 4-hydroxyphenylacetate 3-monooxygenase. 
                EC 1.14.13.4                      melilotate 3-monooxygenase 
                EC 1.14.13.5                      imidazoleacetate 4-monooxygenase 
                EC 1.14.13.6                      orcinol 2-monooxygenase 
                EC 1.14.13.7                      phenol 2-monooxygenase (NADPH) 
                EC 1.14.13.8                      flavin-containing monooxygenase 
                EC 1.14.13.9                      kynurenine 3-monooxygenase 
                EC 1.14.13.10                      2,6-dihydroxypyridine 3-monooxygenase 
                EC 1.14.13.11                      trans-cinnamate 4-monooxygenase. Now EC 1.14.14.91, trans-cinnamate 4-monooxygenase 
                EC 1.14.13.12                      benzoate 4-monooxygenase. Now EC 1.14.14.92, benzoate 4-monooxygenase 
                EC 1.14.13.13                      calcidiol 1-monooxygenase. Now classified as EC 1.14.15.18, calcidiol 1-monooxygenase 
                EC 1.14.13.14                      trans-cinnamate 2-monooxygenase 
                EC 1.14.13.15                      cholestanetriol 26-monooxygenase. Now EC 1.14.15.15, cholestanetriol 26-monooxygenase. 
                EC 1.14.13.16                      cyclopentanone monooxygenase 
                EC 1.14.13.17                      cholesterol 7α-monooxygenase. Now EC 1.14.14.23, cholesterol 7α-monooxygenase 
                EC 1.14.13.18                      4-hydroxyphenylacetate 1-monooxygenase 
                EC 1.14.13.19                      taxifolin 8-monooxygenase 
                EC 1.14.13.20                      2,4-dichlorophenol 6-monooxygenase 
                EC 1.14.13.21                      flavonoid 3′-monooxygenase. Now EC 1.14.14.82, flavonoid 3′-monooxygenase. 
                EC 1.14.13.22                      cyclohexanone monooxygenase 
                EC 1.14.13.23                      3-hydroxybenzoate 4-monooxygenase 
                EC 1.14.13.24                      3-hydroxybenzoate 6-monooxygenase 
                EC 1.14.13.25                      methane monooxygenase (soluble) 
                EC 1.14.13.26                      phosphatidylcholine 12-monooxygenase. Now classified as EC 1.14.18.4, phosphatidylcholine 12-monooxygenase. 
                EC 1.14.13.27                      4-aminobenzoate 1-monooxygenase 
                EC 1.14.13.28                      3,9-dihydroxypterocarpan 6a-monooxygenase. Now EC 1.14.14.93, 3,9-dihydroxypterocarpan 6a-monooxygenase 
                EC 1.14.13.29                      4-nitrophenol 2-monooxygenase 
                EC 1.14.13.30                      leukotriene-B4 20-monooxygenase. Now EC 1.14.14.94, leukotriene-B4 20-monooxygenase 
                EC 1.14.13.31                      2-nitrophenol 2-monooxygenase 
                EC 1.14.13.32                      albendazole monooxygenase 
                EC 1.14.13.33                      4-hydroxybenzoate 3-monooxygenase [NAD(P)H] 
                EC 1.14.13.34                      leukotriene-E4 20-monooxygenase 
                EC 1.14.13.35                      anthranilate 3-monooxygenase (deaminating) 
                EC 1.14.13.36                      5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase. Now EC 1.14.14.96, 5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase 
                EC 1.14.13.37                      methyltetrahydroprotoberberine 14-monooxygenase. Now EC 1.14.14.97, methyltetrahydroprotoberberine 14-monooxygenase 
                EC 1.14.13.38                      anhydrotetracycline 6-monooxygenase 
                EC 1.14.13.39                      nitric-oxide synthase (NADPH) 
                EC 1.14.13.40                      anthraniloyl-CoA monooxygenase 
                EC 1.14.13.41                      tyrosine N-monooxygenase. Now EC 1.14.14.36, tyrosine N-monooxygenase 
                EC 1.14.13.42                      hydroxyphenylacetonitrile 2-monooxygenase. The activity is covered by EC 1.14.13.68, 4-hydroxyphenylacetaldehyde oxime monooxygenase, that performs the two consecutive reactions in the conversion of (Z)-4-hydroxyphenylacetaldehyde oxime to (S)-4-hydroxymandelonitrile 
                EC 1.14.13.43                      questin monooxygenase 
                EC 1.14.13.44                      2-hydroxybiphenyl 3-monooxygenase 
                EC 1.14.13.45                      CMP-N-acetylneuraminate monooxygenase. Now EC 1.14.18.2, CMP-N-acetylneuraminate monooxygenase 
                EC 1.14.13.46                      (-)-menthol monooxygenase 
                EC 1.14.13.47                      (S)-limonene 3-monooxygenase. Now EC 1.14.14.99, (S)-limonene 3-monooxygenase 
                EC 1.14.13.48                      (S)-limonene 6-monooxygenase. Now classified as EC 1.14.14.51, (S)-limonene 6-monooxygenase 
                EC 1.14.13.49                      (S)-limonene 7-monooxygenase. Now classified as EC 1.14.14.52, (S)-limonene 7-monooxygenase 
                EC 1.14.13.50                      pentachlorophenol monooxygenase 
                EC 1.14.13.51                      6-oxocineole dehydrogenase 
                EC 1.14.13.52                      isoflavone 3′-hydroxylase. Now EC 1.14.14.88, isoflavone 3′-hydroxylase 
                EC 1.14.13.53                      4′-methoxyisoflavone 2′-hydroxylase. Now EC 1.14.14.89, 4′-methoxyisoflavone 2′-hydroxylase 
                EC 1.14.13.54                      ketosteroid monooxygenase 
                EC 1.14.13.55                      protopine 6-monooxygenase. Now EC 1.14.14.98, protopine 6-monooxygenase 
                EC 1.14.13.56                      dihydrosanguinarine 10-monooxygenase. Now EC 1.14.14.100, dihydrosanguinarine 10-monooxygenase 
                EC 1.14.13.57                      dihydrochelirubine 12-monooxygenase. Now EC 1.14.14.101, dihydrochelirubine 12-monooxygenase 
                EC 1.14.13.58                      benzoyl-CoA 3-monooxygenase 
                EC 1.14.13.59                      L-lysine N6-monooxygenase (NADPH) 
                EC 1.14.13.60                      27-hydroxycholesterol 7α-monooxygenase. Now classified as EC 1.14.14.29, 25/26-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.61                      2-hydroxyquinoline 8-monooxygenase 
                EC 1.14.13.62                      4-hydroxyquinoline 3-monooxygenase 
                EC 1.14.13.63                      3-hydroxyphenylacetate 6-hydroxylase 
                EC 1.14.13.64                      4-hydroxybenzoate 1-hydroxylase 
                EC 1.14.13.65                       2-hydroxyquinoline 8-monooxygenase 
                EC 1.14.13.66                      2-hydroxycyclohexanone 2-monooxygenase 
                EC 1.14.13.67                      quinine 3-monooxygenase. Now EC 1.14.14.55, quinine 3-monooxygenase 
                EC 1.14.13.68                      4-hydroxyphenylacetaldehyde oxime monooxygenase. Now EC 1.14.14.37, 4-hydroxyphenylacetaldehyde oxime monooxygenase 
                EC 1.14.13.69                      alkene monooxygenase 
                EC 1.14.13.70                      sterol 14α-demethylase. Now EC 1.14.14.154, sterol 14α-demethylase 
                EC 1.14.13.71                      N-methylcoclaurine 3′-monooxygenase. Now EC 1.14.14.102, N-methylcoclaurine 3′-monooxygenase 
                EC 1.14.13.72                      methylsterol monooxygenase. Now classified as EC 1.14.18.9, methylsterol monooxygenase 
                EC 1.14.13.73                      tabersonine 16-hydroxylase. Now EC 1.14.14.103, tabersonine 16-hydroxylase 
                EC 1.14.13.74                      7-deoxyloganin 7-hydroxylase. Now EC 1.14.14.85, 7-deoxyloganin 7-hydroxylase 
                EC 1.14.13.75                      vinorine hydroxylase. Now EC 1.14.14.104, vinorine hydroxylase 
                EC 1.14.13.76                      taxane 10β-hydroxylase. Now EC 1.14.14.105, taxane 10β-hydroxylase 
                EC 1.14.13.77                      taxane 13α-hydroxylase. Now EC 1.14.14.106, taxane 13α-hydroxylase 
                EC 1.14.13.78                      ent-kaurene oxidase. Now EC 1.14.14.86, ent-kaurene monooxygenase 
                EC 1.14.13.79                      ent-kaurenoic acid oxidase. Now EC 1.14.14.107, ent-kaurenoic acid oxidase 
                EC 1.14.13.80                      (R)-limonene 6-monooxygenase. Now classified as EC 1.14.14.53, (R)-limonene 6-monooxygenase 
                EC 1.14.13.81                      magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase 
                EC 1.14.13.82                      vanillate monooxygenase 
                EC 1.14.13.83                      precorrin-3B synthase 
                EC 1.14.13.84                      4-hydroxyacetophenone monooxygenase 
                EC 1.14.13.85                      glyceollin synthase. Now EC 1.14.14.135, glyceollin synthase 
                EC 1.14.13.86                      2-hydroxyisoflavanone synthase. This enzyme was classified on the basis of an incorrect reaction. The activity is covered by EC 1.14.14.87, 2-hydroxyisoflavanone synthase 
                EC 1.14.13.87                      licodione synthase. Now EC 1.14.14.140, licodione synthase 
                EC 1.14.13.88                      flavanoid 3,5-hydroxylase. Now EC 1.14.14.81, flavanoid 3,5-hydroxylase 
                EC 1.14.13.89                      isoflavone 2-hydroxylase. Now EC 1.14.14.90, isoflavone 2-hydroxylase 
                EC 1.14.13.90                      zeaxanthin epoxidase. Now EC 1.14.15.21, zeaxanthin epoxidase 
                EC 1.14.13.91                      deoxysarpagine hydroxylase. Now EC 1.14.14.136, deoxysarpagine hydroxylase 
                EC 1.14.13.92                      phenylacetone monooxygenase 
                EC 1.14.13.93                      (+)-abscisic acid 8-hydroxylase. Now EC 1.14.14.137, (+)-abscisic acid 8-hydroxylase 
                EC 1.14.13.94                      lithocholate 6β-hydroxylase. Now EC 1.14.14.138, lithocholate 6β-hydroxylase 
                EC 1.14.13.95                      7α-hydroxycholest-4-en-3-one 12α-hydroxylase. Now included with EC 1.14.14.139, 5β-cholestane-3α,7α-diol 12α-hydroxylase 
                EC 1.14.13.96                      5β-cholestane-3α,7α-diol 12α-hydroxylase. Now EC 1.14.14.139, 5β-cholestane-3α,7α-diol 12α-hydroxylase 
                EC 1.14.13.97                      taurochenodeoxycholate 6α-hydroxylase. Now EC 1.14.14.57, taurochenodeoxycholate 6α-hydroxylase 
                EC 1.14.13.98                      cholesterol 24-hydroxylase. Now EC 1.14.14.25, cholesterol 24-hydroxylase  
                EC 1.14.13.99                      24-hydroxycholesterol 7α-hydroxylase. Now EC 1.14.14.26, 24-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.100                      25/26-hydroxycholesterol 7α-hydroxylase. Now classified as EC 1.14.14.29, 25/26-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.13.101                      senecionine N-oxygenase 
                EC 1.14.13.102                      psoralen synthase. Now EC 1.14.14.141, psoralen synthase 
                EC 1.14.13.103                      8-dimethylallylnaringenin 2-hydroxylase. Now EC 1.14.14.142, 8-dimethylallylnaringenin 2-hydroxylase 
                EC 1.14.13.104                      (+)-menthofuran synthase. Now EC 1.14.14.143, (+)-menthofuran synthase 
                EC 1.14.13.105                      monocyclic monoterpene ketone monooxygenase 
                EC 1.14.13.106                      epi-isozizaene 5-monooxygenase, now classified as EC 1.14.15.39, epi-isozizaene 5-monooxygenase. 
                EC 1.14.13.107                      limonene 1,2-monooxygenase 
                EC 1.14.13.108                      abieta-7,13-diene hydroxylase. Now EC 1.14.14.144, abieta-7,13-diene hydroxylase 
                EC 1.14.13.109                      abieta-7,13-dien-18-ol hydroxylase. Now EC 1.14.14.145, abieta-7,13-dien-18-ol hydroxylase 
                EC 1.14.13.110                      geranylgeraniol 18-hydroxylase. Now EC 1.14.14.146, geranylgeraniol 18-hydroxylase 
                EC 1.14.13.111                      methanesulfonate monooxygenase (NADH) 
                EC 1.14.13.112                      3-epi-6-deoxocathasterone 23-monooxygenase. Now EC 1.14.14.147, 3-epi-6-deoxocathasterone 23-monooxygenase 
                EC 1.14.13.113                      FAD-dependent urate hydroxylase 
                EC 1.14.13.114                      6-hydroxynicotinate 3-monooxygenase 
                EC 1.14.13.115                      angelicin synthase. Now EC 1.14.14.148, angelicin synthase 
                EC 1.14.13.116                      geranylhydroquinone 3-hydroxylase. Now EC 1.14.14.174, geranylhydroquinone 3-hydroxylase. 
                EC 1.14.13.117                      isoleucine N-monooxygenase, Now EC 1.14.14.39, isoleucine N-monooxygenase 
                EC 1.14.13.118                      valine N-monooxygenase. Now EC 1.14.14.38, valine N-monooxygenase 
                EC 1.14.13.119                      5-epiaristolochene 1,3-dihydroxylase. Now EC 1.14.14.149, 5-epiaristolochene 1,3-dihydroxylase 
                EC 1.14.13.120                      costunolide synthase. Now EC 1.14.14.150, costunolide synthase 
                EC 1.14.13.121                      premnaspirodiene oxygenase. Now EC 1.14.14.151, premnaspirodiene oxygenase 
                EC 1.14.13.122                      chlorophyllide-a oxygenase 
                EC 1.14.13.123                      germacrene A hydroxylase. Now EC 1.14.14.95, germacrene A hydroxylase 
                EC 1.14.13.124                      phenylalanine N-monooxygenase, now classified as EC 1.14.14.40, phenylalanine N-monooxygenase 
                EC 1.14.13.125                      tryptophan N-monooxygenase. Now EC 1.14.14.156, tryptophan N-monooxygenase 
                EC 1.14.13.126                      vitamin D3 24-hydroxylase. Now EC 1.14.15.16, vitamin D3 24-hydroxylase 
                EC 1.14.13.127                      3-(3-hydroxyphenyl)propanoate hydroxylase 
                EC 1.14.13.128                      7-methylxanthine demethylase 
                EC 1.14.13.129                      β-carotene 3-hydroxylase. Now EC 1.14.15.24, β-carotene 3-hydroxylase. 
                EC 1.14.13.130                      pyrrole-2-carboxylate monooxygenase 
                EC 1.14.13.131                      dissimilatory dimethyl sulfide monooxygenase 
                EC 1.14.13.132                      squalene monooxygenase. Now EC 1.14.14.17, squalene monooxygenase 
                EC 1.14.13.133                      pentalenene oxygenase. Now EC 1.14.15.32, pentalenene oxygenase 
                EC 1.14.13.134                      β-amyrin 11-oxidase. Now EC 1.14.14.152, β-amyrin 11-oxidase 
                EC 1.14.13.135                      1-hydroxy-2-naphthoate hydroxylase 
                EC 1.14.13.136                      2-hydroxyisoflavanone synthase. Now EC 1.14.14.87, 2-hydroxyisoflavanone synthase 
                EC 1.14.13.137                      indole-2-monooxygenase. Now EC 1.14.14.153, indole-2-monooxygenase 
                EC 1.14.13.138                      indolin-2-one monooxygenase. Now EC 1.14.14.157, indolin-2-one monooxygenase 
                EC 1.14.13.139                      3-hydroxyindolin-2-one monooxygenase. Now EC 1.14.14.109, 3-hydroxyindolin-2-one monooxygenase 
                EC 1.14.13.140                      2-hydroxy-1,4-benzoxazin-3-one monooxygenase. Now EC 1.14.14.110, 2-hydroxy-1,4-benzoxazin-3-one monooxygenase. 
                EC 1.14.13.141                      cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]. Now EC 1.14.15.29, cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming].. 
                EC 1.14.13.142                      3-ketosteroid 9α-monooxygenase. Now EC 1.14.15.30, 3-ketosteroid 9α-monooxygenase 
                EC 1.14.13.143                      ent-isokaurene C2-hydroxylase. Now EC 1.14.14.76 ent-isokaurene C2/C3-hydroxylase 
                EC 1.14.13.144                      9β-pimara-7,15-diene oxidase. Now EC 1.14.14.111, 9β-pimara-7,15-diene oxidase. 
                EC 1.14.13.145                      ent-cassa-12,15-diene 11-hydroxylase. Now EC 1.14.14.112, ent-cassa-12,15-diene 11-hydroxylase. 
                EC 1.14.13.146                      taxoid 14β-hydroxylase 
                EC 1.14.13.147                      taxoid 7β-hydroxylase. Now EC 1.14.14.182, taxoid 7β-hydroxylase 
                EC 1.14.13.148                      trimethylamine monooxygenase 
                EC 1.14.13.149                      phenylacetyl-CoA 1,2-epoxidase 
                EC 1.14.13.150                      α-humulene 10-hydroxylase. Now EC 1.14.14.113, α-humulene 10-hydroxylase. 
                EC 1.14.13.151                      linalool 8-monooxygenase. Now EC 1.14.14.84, linalool 8-monooxygenase 
                EC 1.14.13.152                      geraniol 8-hydroxylase. Now EC 1.14.14.83, geraniol 8-hydroxylase 
                EC 1.14.13.153                      (+)-sabinene 3-hydroxylase 
                EC 1.14.13.154                      erythromycin 12-hydroxylase 
                EC 1.14.13.155                      α-pinene monooxygenase 
                EC 1.14.13.156                      1,8-cineole 2-endo-monooxygenase. Now EC 1.14.14.133, 1,8-cineole 2-endo-monooxygenase 
                EC 1.14.13.157                      1,8-cineole 2-exo-monooxygenase. Now EC 1.14.14.56, 1,8-cineole 2-exo-monooxygenase 
                EC 1.14.13.158                      amorpha-4,11-diene 12-monooxygenase. Now EC 1.14.14.114, amorpha-4,11-diene 12-monooxygenase. 
                EC 1.14.13.159                      vitamin D 25-hydroxylase. Now EC 1.14.14.24, vitamin D 25-hydroxylase 
                EC 1.14.13.160                      (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase 
                EC 1.14.13.161                      (+)-camphor 6-exo-hydroxylase 
                EC 1.14.13.162                      2,5-diketocamphane 1,2-monooxygenase. Now EC 1.14.14.108, 2,5-diketocamphane 1,2-monooxygenase 
                EC 1.14.13.163                      6-hydroxy-3-succinoylpyridine 3-monooxygenase 
                EC 1.14.13.164                      carotenoid isomerooxygenase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 1.13.11.65, carotenoid isomerooxygenase 
                EC 1.14.13.165                      nitric-oxide synthase [NAD(P)H]. Now classified as EC 1.14.14.47, nitric-oxide synthase (flavodoxin) 
                EC 1.14.13.166                      4-nitrocatechol 4-monooxygenase 
                EC 1.14.13.167                      4-nitrophenol 4-monooxygenase 
                EC 1.14.13.168                      indole-3-pyruvate monooxygenase 
                EC 1.14.13.169                      sphinganine C4-monooxygenase. Now EC 1.14.18.5, sphingolipid C4-monooxygenase 
                EC 1.14.13.170                      pentalenolactone D synthase 
                EC 1.14.13.171                      neopentalenolactone D synthase 
                EC 1.14.13.172                      salicylate 5-hydroxylase 
                EC 1.14.13.173                      11-oxo-β-amyrin 30-oxidase. Now EC 1.14.14.115, 11-oxo-β-amyrin 30-oxidase. 
                EC 1.14.13.174                      averantin hydroxylase. Now EC 1.14.14.116, averantin hydroxylase 
                EC 1.14.13.175                      aflatoxin B synthase. Now EC 1.14.14.117, aflatoxin B synthase 
                EC 1.14.13.176                      tryprostatin B 6-hydroxylase. Now EC 1.14.14.118, tryprostatin B 6-hydroxylase 
                EC 1.14.13.177                      fumitremorgin C monooxygenase. Now EC 1.14.14.119, fumitremorgin C monooxygenase 
                EC 1.14.13.178                      methylxanthine N1-demethylase 
                EC 1.14.13.179                      methylxanthine N3-demethylase 
                EC 1.14.13.180                      aklavinone 12-hydroxylase 
                EC 1.14.13.181                      13-deoxydaunorubicin hydroxylase 
                EC 1.14.13.182                      2-heptyl-3-hydroxy-4(1H)-quinolone synthase 
                EC 1.14.13.183                      dammarenediol 12-hydroxylase. Now EC 1.14.14.120, dammarenediol 12-hydroxylase 
                EC 1.14.13.184                      protopanaxadiol 6-hydroxylase. Now EC 1.14.14.121, protopanaxadiol 6-hydroxylase 
                EC 1.14.13.185                      pikromycin synthase. Now EC 1.14.15.33, pikromycin synthase 
                EC 1.14.13.186                      20-oxo-5-O-mycaminosyltylactone 23-monooxygenase. Now EC 1.14.15.34, 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase 
                EC 1.14.13.187                      L-evernosamine nitrososynthase 
                EC 1.14.13.188                      6-deoxyerythronolide B hydroxylase. Now EC 1.14.15.35, 6-deoxyerythronolide B hydroxylase 
                EC 1.14.13.189                      5-methyl-1-naphthoate 3-hydroxylase 
                EC 1.14.13.190                      ferruginol synthase. Now EC 1.14.14.175, ferruginol synthase 
                EC 1.14.13.191                      ent-sandaracopimaradiene 3-hydroxylase. Now EC 1.14.14.70, ent-sandaracopimaradiene 3-hydroxylase 
                EC 1.14.13.192                      oryzalexin E synthase. Now EC 1.14.14.122, oryzalexin E synthase 
                EC 1.14.13.193                      oryzalexin D synthase. Now EC 1.14.14.123, oryzalexin D synthase 
                EC 1.14.13.194                      phylloquinone ω-hydroxylase. Now EC 1.14.14.78, phylloquinone ω-hydroxylase 
                EC 1.14.13.195                      L-ornithine N5-monooxygenase (NADPH) 
                EC 1.14.13.196                      L-ornithine N5-monooxygenase [NAD(P)H] 
                EC 1.14.13.197                      dihydromonacolin L hydroxylase. Now EC 1.14.14.124, dihydromonacolin L hydroxylase 
                EC 1.14.13.198                      monacolin L hydroxylase. Now EC 1.14.14.125, monacolin L hydroxylase 
                EC 1.14.13.199                      docosahexaenoic acid ω-hydroxylase. Now EC 1.14.14.79, docosahexaenoic acid ω-hydroxylase 
                EC 1.14.13.200                      tetracenomycin A2 monooxygenase-dioxygenase 
                EC 1.14.13.201                      β-amyrin 28-monooxygenase. Now EC 1.14.14.126, β-amyrin 28-monooxygenase 
                EC 1.14.13.202                      methyl farnesoate epoxidase. Now EC 1.14.14.127, methyl farnesoate epoxidase 
                EC 1.14.13.203                      farnesoate epoxidase. Now EC 1.14.14.128, farnesoate epoxidase 
                EC 1.14.13.204                      long-chain acyl-CoA ω-monooxygenase. Now EC 1.14.14.129, long-chain acyl-CoA ω-monooxygenase 
                EC 1.14.13.205                      long-chain fatty acid ω-monooxygenase. Now EC 1.14.14.80, long-chain fatty acid ω-monooxygenase 
                EC 1.14.13.206                      laurate 7-monooxygenase. Now EC 1.14.14.130, laurate 7-monooxygenase 
                EC 1.14.13.207                      ipsdienol synthase. Now EC 1.14.14.31, ipsdienol synthase 
                EC 1.14.13.208                      benzoyl-CoA 2,3-epoxidase 
                EC 1.14.13.209                      salicyloyl-CoA 5-hydroxylase 
                EC 1.14.13.210                      4-methyl-5-nitrocatechol 5-monooxygenase 
                EC 1.14.13.211                      rifampicin monooxygenase 
                EC 1.14.13.212                      1,3,7-trimethyluric acid 5-monooxygenase 
                EC 1.14.13.213                      bursehernin 5-monooxygenase. Now EC 1.14.14.131, bursehernin 5-monooxygenase 
                EC 1.14.13.214                      (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase. Now EC 1.14.14.132, (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase 
                EC 1.14.13.215                      protoasukamycin 4-monooxygenase 
                EC 1.14.13.216                      asperlicin C monooxygenase 
                EC 1.14.13.217                      protodeoxyviolaceinate monooxygenase 
                EC 1.14.13.218                      5-methylphenazine-1-carboxylate 1-monooxygenase 
                EC 1.14.13.219                      resorcinol 4-hydroxylase (NADPH) 
                EC 1.14.13.220                      resorcinol 4-hydroxylase (NADH) 
                EC 1.14.13.221                      cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]. Now EC 1.14.15.28, cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] 
                EC 1.14.13.222                      aurachin C monooxygenase/isomerase 
                EC 1.14.13.223                      3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase 
                EC 1.14.13.224                      violacein synthase 
                EC 1.14.13.225                      F-actin monooxygenase 
                EC 1.14.13.226                      acetone monooxygenase (methyl acetate-forming) 
                EC 1.14.13.227                      propane 2-monooxygenase 
                EC 1.14.13.228                      jasmonic acid 12-hydroxylase 
                EC 1.14.13.229                      tert-butyl alcohol monooxygenase 
                EC 1.14.13.230                      butane monooxygenase (soluble) 
                EC 1.14.13.231                      tetracycline 11a-monooxygenase 
                EC 1.14.13.232                      6-methylpretetramide 4-monooxygenase 
                EC 1.14.13.233                      4-hydroxy-6-methylpretetramide 12a-monooxygenase 
                EC 1.14.13.234                      5a,11a-dehydrotetracycline 5-monooxygenase 
                EC 1.14.13.235                      indole-3-acetate monooxygenase 
                EC 1.14.13.236                      toluene 4-monooxygenase 
                EC 1.14.13.237                      aliphatic glucosinolate S-oxygenase 
                EC 1.14.13.238                      dimethylamine monooxygenase 
                EC 1.14.13.239                      carnitine monooxygenase 
                EC 1.14.13.240                      2-polyprenylphenol 6-hydroxylase 
                EC 1.14.13.241                      5-pyridoxate monooxygenase 
                EC 1.14.13.242                      3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase 
                EC 1.14.13.243                      toluene 2-monooxygenase 
                EC 1.14.13.244                      phenol 2-monooxygenase (NADH) 
                EC 1.14.13.245                      assimilatory dimethylsulfide S-monooxygenase 
                EC 1.14.13.246                      4β-methylsterol monooxygenase 
                EC 1.14.13.247                      stachydrine N-demethylase 
                EC 1.14.13.248                      L-aspartate N-monooxygenase (nitrosuccinate-forming) 
                EC 1.14.13.249                      3-amino-4-hydroxybenzoate 2-monooxygenase 
                EC 1.14.13.250                      nitrosourea synthase 
                EC 1.14.13.251                      glycine betaine monooxygenase 
        EC 1.14.14       []    With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.14.1                      unspecific monooxygenase 
                EC 1.14.14.2                       benzopyrene 3-monooxygenase. Now included with EC 1.14.14.1 unspecific monooxygenase 
                EC 1.14.14.3                      bacterial luciferase 
                EC 1.14.14.4                       choline monooxygenase. Identical to EC 1.14.15.7 
                EC 1.14.14.5                      alkanesulfonate monooxygenase 
                EC 1.14.14.6                      methanesulfonate monooxygenase. Now EC 1.14.13.111, methanesulfonate monooxygenase. Formerly thought to involve FMNH2 but now shown to use NADH. 
                EC 1.14.14.7                      tryptophan 7-halogenase. As oxygen is completely reduced to H2O and is not incorporated into the donor chloride, the enzyme has been transferred to EC 1.14.19.9, tryptophan 7-halogenase 
                EC 1.14.14.8                      anthranilate 3-monooxygenase (FAD) 
                EC 1.14.14.9                      4-hydroxyphenylacetate 3-monooxygenase 
                EC 1.14.14.10                      nitrilotriacetate monooxygenase 
                EC 1.14.14.11                      styrene monooxygenase 
                EC 1.14.14.12                      3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase 
                EC 1.14.14.13                      4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase 
                EC 1.14.14.14                      aromatase 
                EC 1.14.14.15                      (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase 
                EC 1.14.14.16                      steroid 21-monooxygenase 
                EC 1.14.14.17                      squalene monooxygenase 
                EC 1.14.14.18                      heme oxygenase (biliverdin-producing) 
                EC 1.14.14.19                      steroid 17α-monooxygenase 
                EC 1.14.14.20                      phenol 2-monooxygenase (FADH2) 
                EC 1.14.14.21                      dibenzothiophene monooxygenase 
                EC 1.14.14.22                      dibenzothiophene sulfone monooxygenase 
                EC 1.14.14.23                      cholesterol 7α-monooxygenase 
                EC 1.14.14.24                      vitamin D 25-hydroxylase 
                EC 1.14.14.25                      cholesterol 24-hydroxylase 
                EC 1.14.14.26                      24-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.14.27                      resorcinol 4-hydroxylase (FADH2) 
                EC 1.14.14.28                      long-chain alkane monooxygenase 
                EC 1.14.14.29                      25/26-hydroxycholesterol 7α-hydroxylase 
                EC 1.14.14.30                      isobutylamine N-monooxygenase 
                EC 1.14.14.31                      ipsdienol synthase 
                EC 1.14.14.32                      17α-hydroxyprogesterone deacetylase 
                EC 1.14.14.33                      ethylenediaminetetraacetate monooxygenase 
                EC 1.14.14.34                      methanesulfonate monooxygenase (FMNH2) 
                EC 1.14.14.35                      dimethylsulfone monooxygenase 
                EC 1.14.14.36                      tyrosine N-monooxygenase 
                EC 1.14.14.37                      4-hydroxyphenylacetaldehyde oxime monooxygenase 
                EC 1.14.14.38                      valine N-monooxygenase 
                EC 1.14.14.39                      isoleucine N-monooxygenase 
                EC 1.14.14.40                      phenylalanine N-monooxygenase 
                EC 1.14.14.41                      (E)-2-methylbutanal oxime monooxygenase 
                EC 1.14.14.42                      homomethionine N-monooxygenase 
                EC 1.14.14.43                      (methylsulfanyl)alkanaldoxime N-monooxygenase 
                EC 1.14.14.44                      phenylacetaldehyde oxime monooxygenase 
                EC 1.14.14.45                      aromatic aldoxime N-monooxygenase 
                EC 1.14.14.46                      pimeloyl-[acyl-carrier protein] synthase 
                EC 1.14.14.47                      nitric-oxide synthase (flavodoxin) 
                EC 1.14.14.48                      jasmonoyl-L-amino acid 12-hydroxylase 
                EC 1.14.14.49                      12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase 
                EC 1.14.14.50                      tabersonine 3-oxygenase 
                EC 1.14.14.51                      (S)-limonene 6-monooxygenase 
                EC 1.14.14.52                      (S)-limonene 7-monooxygenase 
                EC 1.14.14.53                      (R)-limonene 6-monooxygenase 
                EC 1.14.14.54                      phenylacetate 2-hydroxylase 
                EC 1.14.14.55                      quinine 3-monooxygenase 
                EC 1.14.14.56                      1,8-cineole 2-exo-monooxygenase 
                EC 1.14.14.57                      taurochenodeoxycholate 6α-hydroxylase 
                EC 1.14.14.58                      trimethyltridecatetraene synthase 
                EC 1.14.14.59                      dimethylnonatriene synthase 
                EC 1.14.14.60                      ferruginol monooxygenase 
                EC 1.14.14.61                      carnosic acid synthase 
                EC 1.14.14.62                      salviol synthase 
                EC 1.14.14.63                      β-amyrin 16β-monooxygenase 
                EC 1.14.14.64                      β-amyrin 6β-monooxygenase 
                EC 1.14.14.65                      sugiol synthase 
                EC 1.14.14.66                      marmesin synthase 
                EC 1.14.14.67                      11-hydroxysugiol 20-monooxygenase 
                EC 1.14.14.68                      syn-pimaradiene 3-monooxygenase 
                EC 1.14.14.69                      ent-cassadiene hydroxylase 
                EC 1.14.14.70                      ent-sandaracopimaradiene 3-hydroxylase 
                EC 1.14.14.71                      cucurbitadienol 11-hydroxylase 
                EC 1.14.14.72                      drimenol monooxygenase 
                EC 1.14.14.73                      albendazole monooxygenase (sulfoxide-forming) 
                EC 1.14.14.74                      albendazole monooxygenase (hydroxylating) 
                EC 1.14.14.75                      fenbendazole monooxygenase (4′-hydroxylating) 
                EC 1.14.14.76                      ent-isokaurene C2/C3-hydroxylase 
                EC 1.14.14.77                      phenylacetonitrile α-monooxygenase 
                EC 1.14.14.78                      phylloquinone ω-hydroxylase 
                EC 1.14.14.79                      docosahexaenoic acid ω-hydroxylase 
                EC 1.14.14.80                      long-chain fatty acid ω-monooxygenase 
                EC 1.14.14.81                      flavanoid 3′,5′-hydroxylase 
                EC 1.14.14.82                      flavonoid 3′-monooxygenase 
                EC 1.14.14.83                      geraniol 8-hydroxylase 
                EC 1.14.14.84                      linalool 8-monooxygenase 
                EC 1.14.14.85                      7-deoxyloganate 7-hydroxylase 
                EC 1.14.14.86                      ent-kaurene monooxygenase 
                EC 1.14.14.87                      2-hydroxyisoflavanone synthase 
                EC 1.14.14.88                      isoflavone 3′-hydroxylase 
                EC 1.14.14.89                      4′-methoxyisoflavone 2′-hydroxylase 
                EC 1.14.14.90                      isoflavone 2′-hydroxylase 
                EC 1.14.14.91                      trans-cinnamate 4-monooxygenase 
                EC 1.14.14.92                      benzoate 4-monooxygenase 
                EC 1.14.14.93                      3,9-dihydroxypterocarpan 6a-monooxygenase 
                EC 1.14.14.94                      leukotriene-B4 20-monooxygenase 
                EC 1.14.14.95                      germacrene A hydroxylase 
                EC 1.14.14.96                      5-O-(4-coumaroyl)-D-quinate 3′-monooxygenase 
                EC 1.14.14.97                      methyltetrahydroprotoberberine 14-monooxygenase 
                EC 1.14.14.98                      protopine 6-monooxygenase 
                EC 1.14.14.99                      (S)-limonene 3-monooxygenase 
                EC 1.14.14.100                      dihydrosanguinarine 10-monooxygenase 
                EC 1.14.14.101                      dihydrochelirubine 12-monooxygenase 
                EC 1.14.14.102                      N-methylcoclaurine 3′-monooxygenase 
                EC 1.14.14.103                      tabersonine 16-hydroxylase 
                EC 1.14.14.104                      vinorine hydroxylase 
                EC 1.14.14.105                      taxane 10β-hydroxylase 
                EC 1.14.14.106                      taxane 13α-hydroxylase 
                EC 1.14.14.107                      ent-kaurenoic acid monooxygenase 
                EC 1.14.14.108                      2,5-diketocamphane 1,2-monooxygenase 
                EC 1.14.14.109                      3-hydroxyindolin-2-one monooxygenase 
                EC 1.14.14.110                      2-hydroxy-1,4-benzoxazin-3-one monooxygenase 
                EC 1.14.14.111                      9β-pimara-7,15-diene oxidase 
                EC 1.14.14.112                      ent-cassa-12,15-diene 11-hydroxylase 
                EC 1.14.14.113                      α-humulene 10-hydroxylase 
                EC 1.14.14.114                      amorpha-4,11-diene 12-monooxygenase 
                EC 1.14.14.115                      11-oxo-β-amyrin 30-oxidase 
                EC 1.14.14.116                      averantin hydroxylase 
                EC 1.14.14.117                      aflatoxin B synthase 
                EC 1.14.14.118                      tryprostatin B 6-hydroxylase 
                EC 1.14.14.119                      fumitremorgin C monooxygenase 
                EC 1.14.14.120                      dammarenediol 12-hydroxylase 
                EC 1.14.14.121                      protopanaxadiol 6-hydroxylase 
                EC 1.14.14.122                      oryzalexin E synthase 
                EC 1.14.14.123                      oryzalexin D synthase 
                EC 1.14.14.124                      dihydromonacolin L hydroxylase 
                EC 1.14.14.125                      monacolin L hydroxylase 
                EC 1.14.14.126                      β-amyrin 28-monooxygenase 
                EC 1.14.14.127                      methyl farnesoate epoxidase 
                EC 1.14.14.128                      farnesoate epoxidase 
                EC 1.14.14.129                      long-chain acyl-CoA ω-monooxygenase 
                EC 1.14.14.130                      laurate 7-monooxygenase 
                EC 1.14.14.131                      bursehernin 5′-monooxygenase 
                EC 1.14.14.132                      (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase 
                EC 1.14.14.133                      1,8-cineole 2-endo-monooxygenase 
                EC 1.14.14.134                      β-amyrin 24-hydroxylase 
                EC 1.14.14.135                      glyceollin synthase 
                EC 1.14.14.136                      deoxysarpagine hydroxylase 
                EC 1.14.14.137                      (+)-abscisic acid 8′-hydroxylase 
                EC 1.14.14.138                      lithocholate 6β-hydroxylase 
                EC 1.14.14.139                      5β-cholestane-3α,7α-diol 12α-hydroxylase 
                EC 1.14.14.140                      licodione synthase. Now included with EC 1.14.14.162, flavanone 2-hydroxylase 
                EC 1.14.14.141                      psoralen synthase 
                EC 1.14.14.142                      8-dimethylallylnaringenin 2′-hydroxylase 
                EC 1.14.14.143                      (+)-menthofuran synthase 
                EC 1.14.14.144                      abieta-7,13-diene hydroxylase 
                EC 1.14.14.145                      abieta-7,13-dien-18-ol hydroxylase 
                EC 1.14.14.146                      geranylgeraniol 18-hydroxylase 
                EC 1.14.14.147                      22α-hydroxysteroid 23-monooxygenase 
                EC 1.14.14.148                      angelicin synthase 
                EC 1.14.14.149                      5-epiaristolochene 1,3-dihydroxylase 
                EC 1.14.14.150                      costunolide synthase 
                EC 1.14.14.151                      premnaspirodiene oxygenase 
                EC 1.14.14.152                      β-amyrin 11-oxidase 
                EC 1.14.14.153                      indole-2-monooxygenase 
                EC 1.14.14.154                      sterol 14α-demethylase 
                EC 1.14.14.155                      3,6-diketocamphane 1,2-monooxygenase 
                EC 1.14.14.156                      tryptophan N-monooxygenase 
                EC 1.14.14.157                      indolin-2-one monooxygenase 
                EC 1.14.14.158                      carotenoid ε hydroxylase 
                EC 1.14.14.159                      dolabradiene monooxygenase 
                EC 1.14.14.160                      zealexin A1 synthase 
                EC 1.14.14.161                      nepetalactol monooxygenase 
                EC 1.14.14.162                      flavanone 2-hydroxylase 
                EC 1.14.14.163                      (S)-1-hydroxy-N-methylcanadine 13-hydroxylase 
                EC 1.14.14.164                      fraxetin 5-hydroxylase 
                EC 1.14.14.165                      indole-3-carbonyl nitrile 4-hydroxylase 
                EC 1.14.14.166                      (S)-N-methylcanadine 1-hydroxylase 
                EC 1.14.14.167                      (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase 
                EC 1.14.14.168                      germacrene A acid 8β-hydroxylase 
                EC 1.14.14.169                      eupatolide synthase 
                EC 1.14.14.170                      8-epi-inunolide synthase 
                EC 1.14.14.171                      β-amyrin 16α-hydroxylase 
                EC 1.14.14.172                      3,5,6-trichloropyridin-2-ol monooxygenase 
                EC 1.14.14.173                      2,4,6-trichlorophenol monooxygenase 
                EC 1.14.14.174                      geranylhydroquinone 3′′-hydroxylase 
                EC 1.14.14.175                      ferruginol synthase 
                EC 1.14.14.176                      taxadiene 5α-hydroxylase 
                EC 1.14.14.177                      ultra-long-chain fatty acid ω-hydroxylase 
                EC 1.14.14.178                      steroid 22S-hydroxylase 
                EC 1.14.14.179                      brassinosteroid 6-oxygenase 
                EC 1.14.14.180                      brassinolide synthase 
                EC 1.14.14.181                      sulfoquinovose monooxygenase 
                EC 1.14.14.182                      taxoid 7β-hydroxylase 
                EC 1.14.14.183                      taxoid 2α-hydroxylase 
                EC 1.14.14.184                      5-dehydro-6-demethoxyfumagillol synthase 
        EC 1.14.15       []    With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.15.1                      camphor 5-monooxygenase 
                EC 1.14.15.2                      camphor 1,2-monooxygenase. Now EC 1.14.13.162, 2,5-diketocamphane 1,2-monooxygenase. 
                EC 1.14.15.3                      alkane 1-monooxygenase 
                EC 1.14.15.4                      steroid 11β-monooxygenase 
                EC 1.14.15.5                      corticosterone 18-monooxygenase 
                EC 1.14.15.6                      cholesterol monooxygenase (side-chain-cleaving) 
                EC 1.14.15.7                      choline monooxygenase 
                EC 1.14.15.8                      steroid 15β-monooxygenase 
                EC 1.14.15.9                      spheroidene monooxygenase 
                EC 1.14.15.10                      (+)-camphor 6-endo-hydroxylase 
                EC 1.14.15.11                      pentalenic acid synthase 
                EC 1.14.15.12                      pimeloyl-[acyl-carrier protein] synthase. Now EC 1.14.14.46, pimeloyl-[acyl-carrier protein] synthase 
                EC 1.14.15.13                      pulcherriminic acid synthase 
                EC 1.14.15.14                      methyl-branched lipid ω-hydroxylase 
                EC 1.14.15.15                      cholestanetriol 26-monooxygenase 
                EC 1.14.15.16                      vitamin D3 24-hydroxylase 
                EC 1.14.15.17                      pheophorbide a oxygenase 
                EC 1.14.15.18                      calcidiol 1-monooxygenase 
                EC 1.14.15.19                      C-19 steroid 1α-hydroxylase 
                EC 1.14.15.20                      heme oxygenase (biliverdin-producing, ferredoxin) 
                EC 1.14.15.21                      zeaxanthin epoxidase 
                EC 1.14.15.22                      vitamin D 1,25-hydroxylase 
                EC 1.14.15.23                      chloroacetanilide N-alkylformylase 
                EC 1.14.15.24                      β-carotene 3-hydroxylase 
                EC 1.14.15.25                      p-cymene methyl-monooxygenase 
                EC 1.14.15.26                      toluene methyl-monooxygenase 
                EC 1.14.15.27                      β-dihydromenaquinone-9 ω-hydroxylase 
                EC 1.14.15.28                      cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] 
                EC 1.14.15.29                      cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] 
                EC 1.14.15.30                      3-ketosteroid 9α-monooxygenase 
                EC 1.14.15.31                      2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase 
                EC 1.14.15.32                      pentalenene oxygenase 
                EC 1.14.15.33                      pikromycin synthase 
                EC 1.14.15.34                      20-oxo-5-O-mycaminosyltylactone 23-monooxygenase 
                EC 1.14.15.35                      6-deoxyerythronolide B hydroxylase 
                EC 1.14.15.36                      sterol 14α-demethylase (ferredoxin) 
                EC 1.14.15.37                      luteothin monooxygenase 
                EC 1.14.15.38                      N,N-dimethyl phenylurea N-demethylase 
                EC 1.14.15.39                      epi-isozizaene 5-monooxygenase 
        EC 1.14.16       []    With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.16.1                      phenylalanine 4-monooxygenase 
                EC 1.14.16.2                      tyrosine 3-monooxygenase 
                EC 1.14.16.3                      anthranilate 3-monooxygenase. Withdrawn owing to insufficient evidence. 
                EC 1.14.16.4                      tryptophan 5-monooxygenase 
                EC 1.14.16.5                      alkylglycerol monooxygenase 
                EC 1.14.16.6                      mandelate 4-monooxygenase 
                EC 1.14.16.7                      phenylalanine 3-monooxygenase 
        EC 1.14.17       []    With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.17.1                      dopamine β-monooxygenase 
                EC 1.14.17.2                       4-coumarate 3-monooxygenase. Now included with EC 1.14.18.1 monophenol monooxygenase 
                EC 1.14.17.3                      peptidylglycine monooxygenase 
                EC 1.14.17.4                      aminocyclopropanecarboxylate oxidase 
        EC 1.14.18       []    With another compound as one donor, and incorporation of one atom of oxygen into the other donor 
                EC 1.14.18.1                      tyrosinase 
                EC 1.14.18.2                      CMP-N-acetylneuraminate monooxygenase 
                EC 1.14.18.3                      methane monooxygenase (particulate) 
                EC 1.14.18.4                      phosphatidylcholine 12-monooxygenase 
                EC 1.14.18.5                      sphingolipid C4-monooxygenase 
                EC 1.14.18.6                      4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase 
                EC 1.14.18.7                      dihydroceramide fatty acyl 2-hydroxylase 
                EC 1.14.18.8                      7α-hydroxycholest-4-en-3-one 12α-hydroxylase. Now included with EC 1.14.14.139, 5β-cholestane-3α,7α-diol 12α-hydroxylase 
                EC 1.14.18.9                      4α-methylsterol monooxygenase 
                EC 1.14.18.10                      plant 4,4-dimethylsterol C-4α-methyl-monooxygenase 
                EC 1.14.18.11                      plant 4α-monomethylsterol monooxygenase 
                EC 1.14.18.12                      2-hydroxy fatty acid dioxygenase 
        EC 1.14.19       []    With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water 
                EC 1.14.19.1                      stearoyl-CoA 9-desaturase 
                EC 1.14.19.2                      stearoyl-[acyl-carrier-protein] 9-desaturase 
                EC 1.14.19.3                      acyl-CoA 6-desaturase 
                EC 1.14.19.4                      acyl-lipid (11-3)-desaturase 
                EC 1.14.19.5                      acyl-CoA 11-(Z)-desaturase 
                EC 1.14.19.6                      acyl-CoA (9+3)-desaturase 
                EC 1.14.19.7                      (S)-2-hydroxypropylphosphonic acid epoxidase. Now EC 1.11.1.23, (S)-2-hydroxypropylphosphonic acid epoxidase. 
                EC 1.14.19.8                      pentalenolactone synthase 
                EC 1.14.19.9                      tryptophan 7-halogenase 
                EC 1.14.19.10                      icosanoyl-CoA 5-desaturase 
                EC 1.14.19.11                      acyl-[acyl-carrier-protein] 4-desaturase 
                EC 1.14.19.12                      acyl-lipid ω-(9-4) desaturase 
                EC 1.14.19.13                      acyl-CoA 15-desaturase 
                EC 1.14.19.14                      linoleoyl-lipid Δ9 conjugase 
                EC 1.14.19.15                      (11Z)-hexadec-11-enoyl-CoA conjugase 
                EC 1.14.19.16                      linoleoyl-lipid Δ12 conjugase (11E,13Z-forming) 
                EC 1.14.19.17                      sphingolipid 4-desaturase 
                EC 1.14.19.18                      sphingolipid 8-(E)-desaturase 
                EC 1.14.19.19                      sphingolipid 10-desaturase 
                EC 1.14.19.20                      Δ7-sterol 5(6)-desaturase 
                EC 1.14.19.21                      cholesterol 7-desaturase 
                EC 1.14.19.22                      acyl-lipid ω-6 desaturase (cytochrome b5) 
                EC 1.14.19.23                      acyl-lipid (n+3)-(Z)-desaturase (ferredoxin) 
                EC 1.14.19.24                      acyl-CoA 11-(E)-desaturase 
                EC 1.14.19.25                      acyl-lipid ω-3 desaturase (cytochrome b5) 
                EC 1.14.19.26                      acyl-[acyl-carrier-protein] 6-desaturase 
                EC 1.14.19.27                      sn-2 palmitoyl-lipid 9-desaturase 
                EC 1.14.19.28                      sn-1 stearoyl-lipid 9-desaturase 
                EC 1.14.19.29                      sphingolipid 8-(E/Z)-desaturase 
                EC 1.14.19.30                      acyl-lipid (8-3)-desaturase 
                EC 1.14.19.31                      acyl-lipid (7-3)-desaturase 
                EC 1.14.19.32                      palmitoyl-CoA 14-(E/Z)-desaturase 
                EC 1.14.19.33                      Δ12 acyl-lipid conjugase (11E,13E-forming) 
                EC 1.14.19.34                      acyl-lipid (9+3)-(E)-desaturase 
                EC 1.14.19.35                      sn-2 acyl-lipid ω-3 desaturase (ferredoxin) 
                EC 1.14.19.36                      sn-1 acyl-lipid ω-3 desaturase (ferredoxin) 
                EC 1.14.19.37                      acyl-CoA 5-desaturase 
                EC 1.14.19.38                      acyl-lipid Δ6-acetylenase 
                EC 1.14.19.39                      acyl-lipid Δ12-acetylenase 
                EC 1.14.19.40                      hex-5-enoyl-[acyl-carrier protein] acetylenase 
                EC 1.14.19.41                      sterol 22-desaturase 
                EC 1.14.19.42                      palmitoyl-[glycerolipid] 7-desaturase 
                EC 1.14.19.43                      palmitoyl-[glycerolipid] 3-(E)-desaturase 
                EC 1.14.19.44                      acyl-CoA (8-3)-desaturase 
                EC 1.14.19.45                      sn-1 oleoyl-lipid 12-desaturase 
                EC 1.14.19.46                      sn-1 linoleoyl-lipid 6-desaturase 
                EC 1.14.19.47                      acyl-lipid (9-3)-desaturase 
                EC 1.14.19.48                      tert-amyl alcohol desaturase 
                EC 1.14.19.49                      tetracycline 7-halogenase 
                EC 1.14.19.50                      noroxomaritidine synthase 
                EC 1.14.19.51                      (S)-corytuberine synthase 
                EC 1.14.19.52                      camalexin synthase 
                EC 1.14.19.53                      all-trans-retinol 3,4-desaturase 
                EC 1.14.19.54                      1,2-dehydroreticuline synthase 
                EC 1.14.19.55                      4-hydroxybenzoate brominase (decarboxylating) 
                EC 1.14.19.56                      1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase 
                EC 1.14.19.57                      1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase 
                EC 1.14.19.58                      tryptophan 5-halogenase 
                EC 1.14.19.59                      tryptophan 6-halogenase 
                EC 1.14.19.60                      7-chloro-L-tryptophan 6-halogenase 
                EC 1.14.19.61                      dihydrorhizobitoxine desaturase 
                EC 1.14.19.62                      secologanin synthase 
                EC 1.14.19.63                      pseudobaptigenin synthase 
                EC 1.14.19.64                      (S)-stylopine synthase 
                EC 1.14.19.65                      (S)-cheilanthifoline synthase 
                EC 1.14.19.66                      berbamunine synthase 
                EC 1.14.19.67                      salutaridine synthase 
                EC 1.14.19.68                      (S)-canadine synthase 
                EC 1.14.19.69                      biflaviolin synthase 
                EC 1.14.19.70                      mycocyclosin synthase 
                EC 1.14.19.71                      fumitremorgin C synthase 
                EC 1.14.19.72                      (–)-pluviatolide synthase 
                EC 1.14.19.73                      (S)-nandinine synthase 
                EC 1.14.19.74                      (+)-piperitol/(+)-sesamin synthase 
                EC 1.14.19.75                      very-long-chain acyl-lipid ω-9 desaturase 
                EC 1.14.19.76                      flavone synthase II 
                EC 1.14.19.77                      plasmanylethanolamine desaturase 
                EC 1.14.19.78                      decanoyl-[acyl-carrier protein] acetylenase 
                EC 1.14.19.79                      3β,22α-dihydroxysteroid 3-dehydrogenase 
        EC 1.14.20       []    With 2-oxoglutarate as one donor, and the other dehydrogenated 
                EC 1.14.20.1                      deacetoxycephalosporin-C synthase 
                EC 1.14.20.2                      2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase. Now EC 1.14.11.59, 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase 
                EC 1.14.20.3                      (5R)-carbapenem-3-carboxylate synthase 
                EC 1.14.20.4                      anthocyanidin synthase 
                EC 1.14.20.5                      flavone synthase I 
                EC 1.14.20.6                      flavonol synthase 
                EC 1.14.20.7                      2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) 
                EC 1.14.20.8                      (–)-deoxypodophyllotoxin synthase 
                EC 1.14.20.9                      L-tyrosine isonitrile desaturase 
                EC 1.14.20.10                      L-tyrosine isonitrile desaturase/decarboxylase 
                EC 1.14.20.11                      3-[(Z)-2-isocyanoethenyl]-1H-indole synthase 
                EC 1.14.20.12                      3-[(E)-2-isocyanoethenyl]-1H-indole synthase 
                EC 1.14.20.13                      6β-hydroxyhyoscyamine epoxidase 
                EC 1.14.20.14                      hapalindole-type alkaloid chlorinase 
                EC 1.14.20.15                      L-threonyl-[L-threonyl-carrier protein] 4-chlorinase 
        EC 1.14.21       []    With NADH or NADPH as one donor, and the other dehydrogenated 
                EC 1.14.21.1                      (S)-stylopine synthase. Now EC 1.14.19.64, (S)-stylopine synthase 
                EC 1.14.21.2                      (S)-cheilanthifoline synthase. Now EC 1.14.19.65, (S)-cheilanthifoline synthase 
                EC 1.14.21.3                      berbamunine synthase. Now EC 1.14.19.66, berbamunine synthase 
                EC 1.14.21.4                      salutaridine synthase. Now EC 1.14.19.67, salutaridine synthase 
                EC 1.14.21.5                      (S)-canadine synthase. Now EC 1.14.19.68, (S)-canadine synthase 
                EC 1.14.21.6                      lathosterol oxidase. Now EC 1.14.19.20, Δ7-sterol 5(6)-desaturase 
                EC 1.14.21.7                      biflaviolin synthase. Now EC 1.14.19.69, biflaviolin synthase 
                EC 1.14.21.8                      pseudobaptigenin synthase. Now EC 1.14.19.63, pseudobaptigenin synthase. 
                EC 1.14.21.9                      mycocyclosin synthase. Now EC 1.14.19.70, mycocyclosin synthase 
                EC 1.14.21.10                      fumitremorgin C synthase. Now EC 1.14.19.71, fumitremorgin C synthase 
                EC 1.14.21.11                      (–)-pluviatolide synthase. Now EC 1.14.19.72, (–)-pluviatolide synthase 
                EC 1.14.21.12                      (S)-nandinine synthase. Now EC 1.14.19.73, (S)-nandinine synthase 
        EC 1.14.99       []    Miscellaneous 
                EC 1.14.99.1                      prostaglandin-endoperoxide synthase 
                EC 1.14.99.2                      kynurenine 7,8-hydroxylase 
                EC 1.14.99.3                      heme oxygenase (biliverdin-producing). Now EC 1.14.14.18, heme oxygenase (biliverdin-producing) 
                EC 1.14.99.4                      progesterone monooxygenase 
                EC 1.14.99.5                      stearoyl-CoA desaturase. Now EC 1.14.19.1, stearoyl-CoA 9-desaturase 
                EC 1.14.99.6                      acyl-[acyl-carrier-protein] desaturase. Now EC 1.14.19.2, acyl-[acyl-carrier-protein] desaturase 
                EC 1.14.99.7                      squalene monooxygenase. Transferred to EC 1.14.13.132, squalene monooxygenase. 
                EC 1.14.99.8                       arene monooxygenase (epoxidizing). Now included with EC 1.14.14.1 unspecific monooxygenase 
                EC 1.14.99.9                      steroid 17α-monooxygenase, now classified as EC 1.14.14.19, steroid 17α-monooxygenase 
                EC 1.14.99.10                      steroid 21-monooxygenase. Now EC 1.14.14.16, steroid 21-monooxygenase 
                EC 1.14.99.11                      estradiol 6β-monooxygenase 
                EC 1.14.99.12                      androst-4-ene-3,17-dione monooxygenase 
                EC 1.14.99.13                      3-hydroxybenzoate 4-monooxygenase. Now EC 1.14.13.23, 3-hydroxybenzoate 4-monooxygenase 
                EC 1.14.99.14                      progesterone 11α-monooxygenase 
                EC 1.14.99.15                      4-methoxybenzoate monooxygenase (O-demethylating) 
                EC 1.14.99.16                      methylsterol monooxygenase. Now EC 1.14.13.72, methylsterol monooxygenase 
                EC 1.14.99.17                      glyceryl-ether monooxygenase. Now EC 1.14.16.5, glyceryl-ether monooxygenase 
                EC 1.14.99.18                       CMP-N-acetylneuraminate monooxygenase 
                EC 1.14.99.19                      plasmanylethanolamine desaturase. Now classified as EC 1.14.19.77, plasmanylethanolamine desaturase 
                EC 1.14.99.20                      phylloquinone monooxygenase (2,3-epoxidizing) 
                EC 1.14.99.21                      Latia-luciferin monooxygenase (demethylating) 
                EC 1.14.99.22                      ecdysone 20-monooxygenase 
                EC 1.14.99.23                      3-hydroxybenzoate 2-monooxygenase 
                EC 1.14.99.24                      steroid 9α-monooxygenase 
                EC 1.14.99.25                      linoleoyl-CoA desaturase. Now EC 1.14.19.3, linoleoyl-CoA desaturase 
                EC 1.14.99.26                      2-hydroxypyridine 5-monooxygenase 
                EC 1.14.99.27                      juglone 3-monooxygenase, now classified as EC 1.17.3.4, juglone 3-monooxygenase 
                EC 1.14.99.28                      linalool 8-monooxygenase. Now EC 1.14.14.84, linalool 8-monooxygenase 
                EC 1.14.99.29                      deoxyhypusine monooxygenase 
                EC 1.14.99.30                      carotene 7,8-desaturase. Now EC 1.3.5.6, 9,9′-dicis-ζ-carotene desaturase. 
                EC 1.14.99.31                      myristoyl-CoA 11-(E) desaturase. Now classified as EC 1.14.19.24, myristoyl-CoA 11-(E) desaturase 
                EC 1.14.99.32                      myristoyl-CoA 11-(Z) desaturase. Now classified as EC 1.14.19.5, acyl-CoA 11-(Z)-desaturase. 
                EC 1.14.99.33                      Δ12-fatty acid dehydrogenase. Now EC 1.14.19.39, acyl-lipid Δ12-acetylenase 
                EC 1.14.99.34                      monoprenyl isoflavone epoxidase 
                EC 1.14.99.35                      thiophene-2-carbonyl-CoA monooxygenase 
                EC 1.14.99.36                      β-carotene 15,15-monooxygenase. Now classified as EC 1.13.11.63, β-carotene 15,15′-dioxygenase. 
                EC 1.14.99.37                      taxadiene 5α-hydroxylase. Now EC 1.14.14.176, taxadiene 5α-hydroxylase 
                EC 1.14.99.38                      cholesterol 25-monooxygenase 
                EC 1.14.99.39                      ammonia monooxygenase 
                EC 1.14.99.40                      5,6-dimethylbenzimidazole synthase. Now EC 1.13.11.79, 5,6-dimethylbenzimidazole synthase 
                EC 1.14.99.41                      all-trans-8′-apo-β-carotenal 15,15′-oxygenase. Now EC 1.13.11.75, all-trans-8′-apo-β-carotenal 15,15′-oxygenase 
                EC 1.14.99.42                      zeaxanthin 7,8-dioxygenase. Now EC 1.13.11.84, crocetin dialdehyde synthase 
                EC 1.14.99.43                      β-amyrin 24-hydroxylase. Now EC 1.14.14.134, β-amyrin 24-hydroxylase 
                EC 1.14.99.44                      diapolycopene oxygenase 
                EC 1.14.99.45                      carotene ε-monooxygenase. Now EC 1.14.14.158, carotene ε-monooxygenase 
                EC 1.14.99.46                      pyrimidine oxygenase 
                EC 1.14.99.47                      (+)-larreatricin hydroxylase 
                EC 1.14.99.48                      heme oxygenase (staphylobilin-producing) 
                EC 1.14.99.49                      2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase. Now EC 1.14.15.31, 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase 
                EC 1.14.99.50                      γ-glutamyl hercynylcysteine S-oxide synthase 
                EC 1.14.99.51                      hercynylcysteine S-oxide synthase, now listed as EC 1.21.3.10, hercynylcysteine S-oxide synthase. 
                EC 1.14.99.52                      L-cysteinyl-L-histidinylsulfoxide synthase 
                EC 1.14.99.53                      lytic chitin monooxygenase 
                EC 1.14.99.54                      lytic cellulose monooxygenase (C1-hydroxylating) 
                EC 1.14.99.55                      lytic starch monooxygenase 
                EC 1.14.99.56                      lytic cellulose monooxygenase (C4-dehydrogenating) 
                EC 1.14.99.57                      heme oxygenase (mycobilin-producing) 
                EC 1.14.99.58                      heme oxygenase (biliverdin-IX-β and δ-forming) 
                EC 1.14.99.59                      tryptamine 4-monooxygenase 
                EC 1.14.99.60                      3-demethoxyubiquinol 3-hydroxylase 
                EC 1.14.99.61                      cyclooctat-9-en-7-ol 5-monooxygenase 
                EC 1.14.99.62                      cyclooctatin synthase 
                EC 1.14.99.63                      β-carotene 4-ketolase 
                EC 1.14.99.64                      zeaxanthin 4-ketolase 
                EC 1.14.99.65                      4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase 
                EC 1.14.99.66                      [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase 
                EC 1.14.99.67                      α-N-dichloroacetyl-p-aminophenylserinol N-oxygenase 
                EC 1.14.99.68                      4-aminobenzoate N-oxygenase 
                EC 1.14.99.69                      tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase 
    EC 1.15  [+]      
        EC 1.15.1       []    Acting on superoxide as acceptor (only sub-subclass identified to date) 
                EC 1.15.1.1                      superoxide dismutase 
                EC 1.15.1.2                      superoxide reductase 
    EC 1.16  [+]      
        EC 1.16.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.16.1.1                      mercury(II) reductase 
                EC 1.16.1.2                      diferric-transferrin reductase 
                EC 1.16.1.3                      aquacobalamin reductase. This entry has been deleted since no specific enzyme catalysing this activity has been identified and it has been shown that aquacobalamin is efficiently reduced by free dihydroflavins and by non-specific reduced flavoproteins. 
                EC 1.16.1.4                      cob(II)alamin reductase. This entry has been deleted since no specific enzyme catalysing this activity has been identified and it has been shown that cob(II)alamin is efficiently reduced by free dihydroflavins and by non-specific reduced flavoproteins 
                EC 1.16.1.5                      aquacobalamin reductase (NADPH). This entry has been deleted since the enzyme the entry was based on was later shown to be EC 1.2.1.51, pyruvate dehydrogenase (NADP+). On the other hand, it has been shown that non-enzymatic reduction of cob(III)alamin to cob(II)alamin occurs efficiently in the presence of free dihydroflavins or non-specific reduced flavoproteins. 
                EC 1.16.1.6                      cyanocobalamin reductase 
                EC 1.16.1.7                      ferric-chelate reductase (NADH) 
                EC 1.16.1.8                      [methionine synthase] reductase 
                EC 1.16.1.9                      ferric-chelate reductase (NADPH) 
                EC 1.16.1.10                      ferric-chelate reductase [NAD(P)H] 
        EC 1.16.3       []    With oxygen as acceptor 
                EC 1.16.3.1                      ferroxidase 
                EC 1.16.3.2                      bacterial non-heme ferritin 
                EC 1.16.3.3                      manganese oxidase 
                EC 1.16.3.4                      cuproxidase 
        EC 1.16.5       []    With a quinone or similar compound as acceptor 
                EC 1.16.5.1                      ascorbate ferrireductase (transmembrane). Now EC 7.2.1.3, ascorbate ferrireductase (transmembrane) 
        EC 1.16.8       []    With a flavin as acceptor 
                EC 1.16.8.1                      cob(II)yrinic acid a,c-diamide reductase. This activity is now known to be catalyzed by EC 2.5.1.17, corrinoid adenosyltransferase 
        EC 1.16.9       []    With a copper protein as acceptor 
                EC 1.16.9.1                      iron:rusticyanin reductase 
        EC 1.16.98       []    With other, known, physiological acceptors 
                EC 1.16.98.1                      Now EC 1.16.9.1 iron:rusticyanin reductase 
        EC 1.16.99       []    With unknown physiological acceptors 
                EC 1.16.99.1                      [Co(II) methylated amine-specific corrinoid protein] reductase 
    EC 1.17  [+]      
        EC 1.17.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.17.1.1                      CDP-4-dehydro-6-deoxyglucose reductase 
                EC 1.17.1.2                      4-hydroxy-3-methylbut-2-enyl diphosphate reductase, now classified as EC 1.17.7.4, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. 
                EC 1.17.1.3                      leucoanthocyanidin reductase 
                EC 1.17.1.4                      xanthine dehydrogenase 
                EC 1.17.1.5                      nicotinate dehydrogenase 
                EC 1.17.1.6                      bile-acid 7α-dehydroxylase. Now EC 1.17.99.5, bile-acid 7α-dehydroxylase. It is now known that FAD is the acceptor and not NAD+ as was thought previously 
                EC 1.17.1.7                      3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. Now EC 1.2.1.91, 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase 
                EC 1.17.1.8                      4-hydroxy-tetrahydrodipicolinate reductase 
                EC 1.17.1.9                      formate dehydrogenase 
                EC 1.17.1.10                      formate dehydrogenase (NADP+) 
                EC 1.17.1.11                      formate dehydrogenase (NAD+, ferredoxin) 
        EC 1.17.2       []    With a cytochrome as acceptor 
                EC 1.17.2.1                      nicotinate dehydrogenase (cytochrome) 
                EC 1.17.2.2                      lupanine 17-hydroxylase (cytochrome c) 
                EC 1.17.2.3                      formate dehydrogenase (cytochrome-c-553) 
        EC 1.17.3       []    With oxygen as acceptor 
                EC 1.17.3.1                      pteridine oxidase 
                EC 1.17.3.2                      xanthine oxidase 
                EC 1.17.3.3                      6-hydroxynicotinate dehydrogenase 
                EC 1.17.3.4                      juglone 3-hydroxylase 
        EC 1.17.4       []    With a disulfide as acceptor 
                EC 1.17.4.1                      ribonucleoside-diphosphate reductase 
                EC 1.17.4.2                      ribonucleoside-triphosphate reductase (thioredoxin) 
                EC 1.17.4.3                      4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase. As ferredoxin and not protein-disulfide is now known to take part in the reaction, the enzyme has been transferred to EC 1.17.7.1, (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase. 
                EC 1.17.4.4                      vitamin-K-epoxide reductase (warfarin-sensitive) 
                EC 1.17.4.5                      vitamin-K-epoxide reductase (warfarin-insensitive) 
        EC 1.17.5       []    With a quinone or similar compound as acceptor 
                EC 1.17.5.1                      phenylacetyl-CoA dehydrogenase 
                EC 1.17.5.2                      caffeine dehydrogenase 
                EC 1.17.5.3                      formate dehydrogenase-N 
        EC 1.17.7       []    With an iron-sulfur protein as acceptor 
                EC 1.17.7.1                      (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) 
                EC 1.17.7.2                      7-hydroxymethyl chlorophyll a reductase 
                EC 1.17.7.3                      (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) 
                EC 1.17.7.4                      4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase 
        EC 1.17.8       []    With a flavin as acceptor 
                EC 1.17.8.1                      hydroxysqualene dehydroxylase 
        EC 1.17.9       []    With a copper protein as acceptor 
                EC 1.17.9.1                      4-methylphenol dehydrogenase (hydroxylating) 
                EC 1.17.9.2                      (+)-pinoresinol hydroxylase 
        EC 1.17.98       []    With other, known, physiological acceptors 
                EC 1.17.98.1                      bile-acid 7α-dehydroxylase. Now known to be catalyzed by multiple enzymes. 
                EC 1.17.98.2                      bacteriochlorophyllide c C-71-hydroxylase 
                EC 1.17.98.3                      formate dehydrogenase (coenzyme F420) 
                EC 1.17.98.4                      formate dehydrogenase (hydrogenase) 
        EC 1.17.99       []    With unknown physiological acceptors 
                EC 1.17.99.1                      4-methylphenol dehydrogenase (hydroxylating). Now EC 1.17.9.1, 4-methylphenol dehydrogenase (hydroxylating) 
                EC 1.17.99.2                      ethylbenzene hydroxylase 
                EC 1.17.99.3                      3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase 
                EC 1.17.99.4                      uracil/thymine dehydrogenase 
                EC 1.17.99.5                      bile-acid 7α-dehydroxylase. Now classified as EC 1.17.98.1, bile-acid 7α-dehydroxylase. 
                EC 1.17.99.6                      epoxyqueuosine reductase 
                EC 1.17.99.7                      formate dehydrogenase (acceptor). Now classified as EC 1.17.98.4, formate dehydrogenase (hydrogenase). 
                EC 1.17.99.8                      limonene dehydrogenase 
                EC 1.17.99.9                      heme a synthase 
                EC 1.17.99.10                      steroid C-25 hydroxylase 
                EC 1.17.99.11                      3-oxo-Δ1-steroid hydratase/dehydrogenase 
    EC 1.18  [+]      
        EC 1.18.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.18.1.1                      rubredoxin—NAD+ reductase 
                EC 1.18.1.2                      ferredoxin—NADP+ reductase 
                EC 1.18.1.3                      ferredoxin—NAD+ reductase 
                EC 1.18.1.4                      rubredoxin—NAD(P)+ reductase 
                EC 1.18.1.5                      putidaredoxin—NAD+ reductase 
                EC 1.18.1.6                      adrenodoxin-NADP+ reductase 
                EC 1.18.1.7                      ferredoxin—NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific) 
                EC 1.18.1.8                      ferredoxin-NAD+ oxidoreductase (Na+-transporting). Now EC 7.2.1.2, ferredoxin—NAD+ oxidoreductase (Na+-transporting) 
        EC 1.18.2       []    With dinitrogen as acceptor (deleted sub-subclass) 
                EC 1.18.2.1                      now EC 1.18.6.1, nitrogenase 
        EC 1.18.3       []    With H+ as acceptor (deleted sub-subclass) 
                EC 1.18.3.1                      hydrogenase. Now EC 1.12.7.2, ferredoxin hydrogenase 
        EC 1.18.6       []    With dinitrogen as acceptor 
                EC 1.18.6.1                      nitrogenase 
                EC 1.18.6.2                      vanadium-dependent nitrogenase 
        EC 1.18.96       []    With other, known, acceptors (deleted sub-subclass) 
                EC 1.18.96.1                      superoxide reductase. Now EC 1.15.1.2, superoxide reductase 
        EC 1.18.99       []    With H+ as acceptor (deleted sub-subclass) 
                EC 1.18.99.1                      hydrogenase. Now EC 1.12.7.2, ferredoxin hydrogenase 
    EC 1.19  [+]      
        EC 1.19.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.19.1.1                      flavodoxin—NADP+ reductase 
        EC 1.19.6       []    With dinitrogen as acceptor 
                EC 1.19.6.1                      nitrogenase (flavodoxin) 
    EC 1.20  [+]      
        EC 1.20.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.20.1.1                      phosphonate dehydrogenase 
        EC 1.20.2       []    With a cytochrome as acceptor 
                EC 1.20.2.1                      arsenate reductase (cytochrome c) 
        EC 1.20.4       []    With disulfide as acceptor 
                EC 1.20.4.1                      arsenate reductase (glutathione/glutaredoxin) 
                EC 1.20.4.2                      methylarsonate reductase 
                EC 1.20.4.3                      mycoredoxin 
                EC 1.20.4.4                      arsenate reductase (thioredoxin) 
        EC 1.20.9       []    With a copper protein as acceptor 
                EC 1.20.9.1                      arsenate reductase (azurin) 
        EC 1.20.98       []    With other, known, physiological acceptors 
                EC 1.20.98.1                      arsenate reductase (azurin). Now EC 1.20.9.1, arsenate reductase (azurin) 
        EC 1.20.99       []    With unknown physiological acceptors 
                EC 1.20.99.1                      arsenate reductase (donor) 
    EC 1.21  [+]      
        EC 1.21.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.21.1.1                      iodotyrosine deiodinase 
                EC 1.21.1.2                      2,4-dichlorobenzoyl-CoA reductase 
        EC 1.21.3       []    With oxygen as acceptor 
                EC 1.21.3.1                      isopenicillin-N synthase 
                EC 1.21.3.2                      columbamine oxidase 
                EC 1.21.3.3                      reticuline oxidase 
                EC 1.21.3.4                      sulochrin oxidase [(+)-bisdechlorogeodin-forming] 
                EC 1.21.3.5                      sulochrin oxidase [(-)-bisdechlorogeodin-forming] 
                EC 1.21.3.6                      aureusidin synthase 
                EC 1.21.3.7                      tetrahydrocannabinolic acid synthase 
                EC 1.21.3.8                      cannabidiolic acid synthase 
                EC 1.21.3.9                      dichlorochromopyrrolate synthase, now classified as EC 1.21.98.2, dichlorochromopyrrolate synthase 
                EC 1.21.3.10                      hercynylcysteine S-oxide synthase 
        EC 1.21.4       []    With a disulfide as acceptor 
                EC 1.21.4.1                      D-proline reductase 
                EC 1.21.4.2                      glycine reductase 
                EC 1.21.4.3                      sarcosine reductase 
                EC 1.21.4.4                      betaine reductase 
                EC 1.21.4.5                      tetrachlorohydroquinone reductive dehalogenase 
        EC 1.21.98       []    With other, known, physiological acceptors 
                EC 1.21.98.1                      cyclic dehypoxanthinyl futalosine synthase 
                EC 1.21.98.2                      dichlorochromopyrrolate synthase 
                EC 1.21.98.3                      anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase 
                EC 1.21.98.4                      PqqA peptide cyclase 
                EC 1.21.98.5                      tetraether lipid synthase 
        EC 1.21.99       []    With unknown physiological acceptors 
                EC 1.21.99.1                      β-cyclopiazonate dehydrogenase 
                EC 1.21.99.2                      EC 1.21.99.2, cyclic dehypoxanthinyl futalosine synthase. Now classified as EC 1.21.98.1, cyclic dehypoxanthinyl futalosine synthase. 
                EC 1.21.99.3                      thyroxine 5-deiodinase 
                EC 1.21.99.4                      thyroxine 5′-deiodinase 
                EC 1.21.99.5                      tetrachloroethene reductive dehalogenase 
    EC 1.22  [+]      
        EC 1.22.1       []    With NAD+ or NADP+ as acceptor 
                EC 1.22.1.1                      iodotyrosine deiodinase. Now EC 1.21.1.1, iodotyrosine deiodinase 
    EC 1.23  [+]      
        EC 1.23.1       []    With NADH or NADPH as donor 
                EC 1.23.1.1                      (+)-pinoresinol reductase 
                EC 1.23.1.2                      (+)-lariciresinol reductase 
                EC 1.23.1.3                      (–)-pinoresinol reductase 
                EC 1.23.1.4                      (–)-lariciresinol reductase 
        EC 1.23.5       []    With a quinone or similar compound as acceptor 
                EC 1.23.5.1                      violaxanthin de-epoxidase 
    EC 1.97  [+]      
        EC 1.97.1       []    Sole sub-subclass for oxidoreductases that do not belong in the other subclasses 
                EC 1.97.1.1                      chlorate reductase 
                EC 1.97.1.2                      pyrogallol hydroxytransferase 
                EC 1.97.1.3                      sulfur reductase. Now EC 1.12.98.4, sulfhydrogenase, since hydrogen is known to be the electron donor. 
                EC 1.97.1.4                      [formate-C-acetyltransferase]-activating enzyme 
                EC 1.97.1.5                      arsenate reductase (glutaredoxin). Now EC 1.20.4.1, arsenate reductase (glutaredoxin) 
                EC 1.97.1.6                      arsenate reductase (donor). Now EC 1.20.99.1, arsenate reductase (donor) 
                EC 1.97.1.7                      methylarsonate reductase. Now EC 1.20.4.2, methylarsonate reductase 
                EC 1.97.1.8                      tetrachloroethene reductive dehalogenase. Now EC 1.21.99.5, tetrachloroethene reductive dehalogenase 
                EC 1.97.1.9                      selenate reductase 
                EC 1.97.1.10                      thyroxine 5′-deiodinase. Now EC 1.21.99.4 thyroxine 5′-deiodinase 
                EC 1.97.1.11                      thyroxine 5-deiodinase. Now EC 1.21.99.3 thyroxine 5-deiodinase. 
                EC 1.97.1.12                      photosystem I 
    EC 1.98  [+]      
    EC 1.99  [+]      
        EC 1.99.1       []    Hydroxylases (now covered by EC 1.14) 
                EC 1.99.1.1                      Now EC 1.12.7.2, ferredoxin hydrogenase 
                EC 1.99.1.2                      Now EC 1.14.16.1, phenylalanine 4-monooxygenase 
                EC 1.99.1.3                      nicotinate 6-hydroxylase 
                EC 1.99.1.4                      tryptophan 5-hydroxylase 
                EC 1.99.1.5                      Now EC 1.14.13.9, kynurenine 3-monooxygenase 
                EC 1.99.1.6                      steroid 11α-hydroxylase 
                EC 1.99.1.7                      Now EC 1.14.15.4, steroid 11β-monooxygenase 
                EC 1.99.1.8                      steroid 6β-hydroxylase 
                EC 1.99.1.9                      Now EC 1.14.99.9, steroid 17α-monooxygenase 
                EC 1.99.1.10                      steroid 19-hydroxylase 
                EC 1.99.1.11                      Now EC 1.14.99.10, steroid 21-monooxygenase 
                EC 1.99.1.12                      alkoxyaryl hydroxylase 
                EC 1.99.1.13                      squalene cyclohydroxylase, covered by EC 1.14.99.7 (squalene monooxygenase) and by EC 5.4.99.7 (lanosterol synthase) 
                EC 1.99.1.14                      Now EC 1.13.11.27, 4-hydroxyphenylpyruvate dioxygenase 
        EC 1.99.2       []    Oxygenases (now covered by EC 1.13) 
                EC 1.99.2.1                      Now EC 1.13.11.12, lipoxygenase 
                EC 1.99.2.2                      Now EC 1.13.11.1, catechol 1,2-dioxygenase 
                EC 1.99.2.3                      Now EC 1.13.11.3, protocatechuate 3,4-dioxygenase 
                EC 1.99.2.4                      Now EC 1.13.11.4, gentisate 1,2-dioxygenase 
                EC 1.99.2.5                      Now EC 1.13.11.5, homogentisate 1,2-dioxygenase 
                EC 1.99.2.6                      Now EC 1.13.99.1, inositol oxygenase 
EC 2 [+]   
    EC 2.1  [+]      
        EC 2.1.1       []    Methyltransferases 
                EC 2.1.1.1                      nicotinamide N-methyltransferase 
                EC 2.1.1.2                      guanidinoacetate N-methyltransferase 
                EC 2.1.1.3                      thetin—homocysteine S-methyltransferase 
                EC 2.1.1.4                      acetylserotonin O-methyltransferase 
                EC 2.1.1.5                      betaine—homocysteine S-methyltransferase 
                EC 2.1.1.6                      catechol O-methyltransferase 
                EC 2.1.1.7                      nicotinate N-methyltransferase 
                EC 2.1.1.8                      histamine N-methyltransferase 
                EC 2.1.1.9                      thiol S-methyltransferase 
                EC 2.1.1.10                      homocysteine S-methyltransferase 
                EC 2.1.1.11                      magnesium protoporphyrin IX methyltransferase 
                EC 2.1.1.12                      methionine S-methyltransferase 
                EC 2.1.1.13                      methionine synthase 
                EC 2.1.1.14                      5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase 
                EC 2.1.1.15                      fatty-acid O-methyltransferase 
                EC 2.1.1.16                      methylene-fatty-acyl-phospholipid synthase 
                EC 2.1.1.17                      phosphatidylethanolamine N-methyltransferase 
                EC 2.1.1.18                      polysaccharide O-methyltransferase 
                EC 2.1.1.19                      trimethylsulfonium—tetrahydrofolate N-methyltransferase 
                EC 2.1.1.20                      glycine N-methyltransferase 
                EC 2.1.1.21                      methylamine—glutamate N-methyltransferase 
                EC 2.1.1.22                      carnosine N-methyltransferase 
                EC 2.1.1.23                       protein-arginine N-methyltransferase. Now listed as EC 2.1.1.124 [cytochrome c]-arginine N-methyltransferase, EC 2.1.1.125 histone-arginine N-methyltransferase and EC 2.1.1.126 [myelin basic protein]-arginine N-methyltransferase 
                EC 2.1.1.24                       protein-γ-glutamate O-methyltransferase. Now listed as EC 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase, EC 2.1.1.80 protein-glutamate O-methyltransferase and EC 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase 
                EC 2.1.1.25                      phenol O-methyltransferase 
                EC 2.1.1.26                      iodophenol O-methyltransferase 
                EC 2.1.1.27                      tyramine N-methyltransferase 
                EC 2.1.1.28                      phenylethanolamine N-methyltransferase 
                EC 2.1.1.29                      tRNA (cytosine-5-)-methyltransferase. Now covered by EC 2.1.1.202 [multisite-specific tRNA:(cytosine-C5)-methyltransferase], EC 2.1.1.203 [tRNA (cytosine34-C5)-methyltransferase] and EC 2.1.1.204 [RNA (cytosine38-C5)-methyltransferase]. 
                EC 2.1.1.30                      tRNA (purine-2- or -6-)-methyltransferase. Reactions previously described are due to EC 2.1.1.32 tRNA (guanine-N2-)-methyltransferase 
                EC 2.1.1.31                      tRNA (guanine-N1-)-methyltransferase. Now covered by EC 2.1.1.221 (tRNA (guanine9-N1)-methyltransferase) and EC 2.1.1.228 (tRNA (guanine37-N1)-methyltransferase). 
                EC 2.1.1.32                      tRNA (guanine-N2-)-methyltransferase. Now covered by EC 2.1.1.213 [tRNA (guanine10-N2)-dimethyltransferase], EC 2.1.1.214 [tRNA (guanine10-N2)-monomethyltransferase], EC 2.1.1.215 [tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase] and EC 2.1.1.216 [tRNA (guanine26-N2)-dimethyltransferase] 
                EC 2.1.1.33                      tRNA (guanine46-N7)-methyltransferase 
                EC 2.1.1.34                      tRNA (guanosine18-2′-O)-methyltransferase 
                EC 2.1.1.35                      tRNA (uracil54-C5)-methyltransferase 
                EC 2.1.1.36                      tRNA (adenine-N1-)-methyltransferase. Now covered by EC 2.1.1.217 (tRNA (adenine22-N1)-methyltransferase), EC 2.1.1.218 (tRNA (adenine9-N1)-methyltransferase), EC 2.1.1.219 (tRNA (adenine57-N1/adenine58-N1)-methyltransferase), EC 2.1.1.220 (tRNA (adenine58-N1)-methyltransferase). 
                EC 2.1.1.37                      DNA (cytosine-5-)-methyltransferase 
                EC 2.1.1.38                      O-demethylpuromycin O-methyltransferase 
                EC 2.1.1.39                      inositol 3-methyltransferase 
                EC 2.1.1.40                      inositol 1-methyltransferase 
                EC 2.1.1.41                      sterol 24-C-methyltransferase 
                EC 2.1.1.42                      flavone 3′-O-methyltransferase 
                EC 2.1.1.43                      histone-lysine N-methyltransferase. Now described by EC 2.1.1.354, [histone H3]-lysine4 N-trimethyltransferase; EC 2.1.1.355, [histone H3]-lysine9 N-trimethyltransferase; EC 2.1.1.356, [histone H3]-lysine27 N-trimethyltransferase; EC 2.1.1.357, [histone H3]-lysine36 N-dimethyltransferase; EC 2.1.1.358, [histone H3]-dimethyl-L-lysine36 N-methyltransferase; EC 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase; EC 2.1.1.360, [histone H3]-lysine79 N-trimethyltransferase; EC 2.1.1.361, [histone H4]-lysine20 N-methyltransferase, and EC 2.1.1.362, [histone H4]-N-methyl-L-lysine20 N-methyltransferase. 
                EC 2.1.1.44                      L-histidine Nα-methyltransferase 
                EC 2.1.1.45                      thymidylate synthase 
                EC 2.1.1.46                      isoflavone 4′-O-methyltransferase 
                EC 2.1.1.47                      indolepyruvate C-methyltransferase 
                EC 2.1.1.48                      rRNA (adenine-N6-)-methyltransferase. Now covered by EC 2.1.1.181 [23S rRNA (adenine1618-N6)-methyltransferase], EC 2.1.1.182 [16S rRNA adenine1518-N6/adenine1519-N6)-dimethyltransferase], EC 2.1.1.183 [18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase] and EC 2.1.1.184 [23S rRNA (adenine2085-N6)-dimethyltransferase] 
                EC 2.1.1.49                      amine N-methyltransferase 
                EC 2.1.1.50                      loganate O-methyltransferase 
                EC 2.1.1.51                      rRNA (guanine-N1-)-methyltransferase. Now covered by EC 2.1.1.187 [23S rRNA (guanine745-N1)-methyltransferase] and EC 2.1.1.188 [23S rRNA (guanine748-N1)-methyltransferase]. 
                EC 2.1.1.52                      rRNA (guanine-N2-)-methyltransferase. Now covered by EC 2.1.1.171 [16S rRNA (guanine966-N2)-methyltransferase], EC 2.1.1.172 [16S rRNA (guanine1207-N2)-methyltransferase], EC 2.1.1.173 [23S rRNA (guanine2445-N2)-methyltransferase] and EC 2.1.1.174 [23S rRNA (guanine1835-N2)-methyltransferase] 
                EC 2.1.1.53                      putrescine N-methyltransferase 
                EC 2.1.1.54                      deoxycytidylate C-methyltransferase 
                EC 2.1.1.55                      tRNA (adenine-N6-)-methyltransferase 
                EC 2.1.1.56                      mRNA (guanine-N7)-methyltransferase 
                EC 2.1.1.57                      methyltransferase cap1 
                EC 2.1.1.58                      mRNA (adenosine-2′-O-)-methyltransferase. Now included with EC 2.1.1.57, mRNA (nucleoside-2′-O-)-methyltransferase 
                EC 2.1.1.59                      [cytochrome c]-lysine N-methyltransferase 
                EC 2.1.1.60                      calmodulin-lysine N-methyltransferase 
                EC 2.1.1.61                      tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase 
                EC 2.1.1.62                      mRNA (2′-O-methyladenosine-N6-)-methyltransferase 
                EC 2.1.1.63                      methylated-DNA—[protein]-cysteine S-methyltransferase 
                EC 2.1.1.64                      3-demethylubiquinol 3-O-methyltransferase 
                EC 2.1.1.65                      licodione 2′-O-methyltransferase 
                EC 2.1.1.66                      rRNA (adenosine-2′-O-)-methyltransferase. Now covered by EC 2.1.1.230, 23S rRNA (adenosine1067-2-O)-methyltransferase. 
                EC 2.1.1.67                      thiopurine S-methyltransferase 
                EC 2.1.1.68                      caffeate O-methyltransferase 
                EC 2.1.1.69                      5-hydroxyfuranocoumarin 5-O-methyltransferase 
                EC 2.1.1.70                      8-hydroxyfuranocoumarin 8-O-methyltransferase 
                EC 2.1.1.71                      phosphatidyl-N-methylethanolamine N-methyltransferase 
                EC 2.1.1.72                      site-specific DNA-methyltransferase (adenine-specific) 
                EC 2.1.1.73                       site-specific DNA-methyltransferase (cytosine-specific). Reaction is that of EC 2.1.1.37, DNA (cytosine-5-)-methyltransferase 
                EC 2.1.1.74                      methylenetetrahydrofolate—tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing] 
                EC 2.1.1.75                      apigenin 4′-O-methyltransferase 
                EC 2.1.1.76                      quercetin 3-O-methyltransferase 
                EC 2.1.1.77                      protein-L-isoaspartate(D-aspartate) O-methyltransferase 
                EC 2.1.1.78                      isoorientin 3′-O-methyltransferase 
                EC 2.1.1.79                      cyclopropane-fatty-acyl-phospholipid synthase 
                EC 2.1.1.80                      protein-glutamate O-methyltransferase 
                EC 2.1.1.81                       nicotine N-methyltransferase. Now included with EC 2.1.1.49 amine N-methyltransferase 
                EC 2.1.1.82                      3-methylquercetin 7-O-methyltransferase 
                EC 2.1.1.83                      3,7-dimethylquercetin 4′-O-methyltransferase 
                EC 2.1.1.84                      methylquercetagetin 6-O-methyltransferase 
                EC 2.1.1.85                      protein-histidine N-methyltransferase 
                EC 2.1.1.86                      tetrahydromethanopterin S-methyltransferase 
                EC 2.1.1.87                      pyridine N-methyltransferase 
                EC 2.1.1.88                      8-hydroxyquercetin 8-O-methyltransferase 
                EC 2.1.1.89                      tetrahydrocolumbamine 2-O-methyltransferase 
                EC 2.1.1.90                      methanol—corrinoid protein Co-methyltransferase 
                EC 2.1.1.91                      isobutyraldoxime O-methyltransferase 
                EC 2.1.1.92                      bergaptol O-methyltransferase. Now included with EC 2.1.1.69, 5-hydroxyfuranocoumarin 5-O-methyltransferase. The reaction with bergaptol is a specific example of the general reaction associated with EC 2.1.1.69 
                EC 2.1.1.93                      xanthotoxol O-methyltransferase. Enzyme is identical to EC 2.1.1.70, 8-hydroxyfuranocoumarin 8-O-methyltransferase 
                EC 2.1.1.94                      tabersonine 16-O-methyltransferase 
                EC 2.1.1.95                      tocopherol C-methyltransferase 
                EC 2.1.1.96                      thioether S-methyltransferase 
                EC 2.1.1.97                      3-hydroxyanthranilate 4-C-methyltransferase 
                EC 2.1.1.98                      diphthine synthase 
                EC 2.1.1.99                      3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase 
                EC 2.1.1.100                      protein-S-isoprenylcysteine O-methyltransferase 
                EC 2.1.1.101                      macrocin O-methyltransferase 
                EC 2.1.1.102                      demethylmacrocin O-methyltransferase 
                EC 2.1.1.103                      phosphoethanolamine N-methyltransferase 
                EC 2.1.1.104                      caffeoyl-CoA O-methyltransferase 
                EC 2.1.1.105                      N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase 
                EC 2.1.1.106                      tryptophan 2-C-methyltransferase 
                EC 2.1.1.107                      uroporphyrinogen-III C-methyltransferase 
                EC 2.1.1.108                      6-hydroxymellein O-methyltransferase 
                EC 2.1.1.109                      demethylsterigmatocystin 6-O-methyltransferase 
                EC 2.1.1.110                      sterigmatocystin 8-O-methyltransferase 
                EC 2.1.1.111                      anthranilate N-methyltransferase 
                EC 2.1.1.112                      glucuronoxylan 4-O-methyltransferase 
                EC 2.1.1.113                      site-specific DNA-methyltransferase (cytosine-N4-specific) 
                EC 2.1.1.114                      polyprenyldihydroxybenzoate methyltransferase 
                EC 2.1.1.115                      (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase 
                EC 2.1.1.116                      3′-hydroxy-N-methyl-(S)-coclaurine 4′-O-methyltransferase 
                EC 2.1.1.117                      (S)-scoulerine 9-O-methyltransferase 
                EC 2.1.1.118                      columbamine O-methyltransferase 
                EC 2.1.1.119                      10-hydroxydihydrosanguinarine 10-O-methyltransferase 
                EC 2.1.1.120                      12-hydroxydihydrochelirubine 12-O-methyltransferase 
                EC 2.1.1.121                      6-O-methylnorlaudanosoline 5′-O-methyltransferase 
                EC 2.1.1.122                      (S)-tetrahydroprotoberberine N-methyltransferase 
                EC 2.1.1.123                      [cytochrome-c]-methionine S-methyltransferase 
                EC 2.1.1.124                      [cytochrome c]-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.125                      histone-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.126                      [myelin basic protein]-arginine N-methyltransferase. Now covered by EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, EC 2.1.1.321, type III protein arginine methyltransferase and EC 2.1.1.322, type IV protein arginine methyltransferase 
                EC 2.1.1.127                      [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase 
                EC 2.1.1.128                      (RS)-norcoclaurine 6-O-methyltransferase 
                EC 2.1.1.129                      inositol 4-methyltransferase 
                EC 2.1.1.130                      precorrin-2 C20-methyltransferase 
                EC 2.1.1.131                      precorrin-3B C17-methyltransferase 
                EC 2.1.1.132                      precorrin-6B C5,15-methyltransferase (decarboxylating) 
                EC 2.1.1.133                      precorrin-4 C11-methyltransferase 
                EC 2.1.1.134                       myo-inositol 6-O-methyltransferase. Now included with EC 2.1.1.129, inositol 4-methyltransferase 
                EC 2.1.1.135                      [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing). Now EC 1.16.1.8, [methionine synthase] reductase 
                EC 2.1.1.136                      chlorophenol O-methyltransferase 
                EC 2.1.1.137                      arsenite methyltransferase 
                EC 2.1.1.138                       methylarsonite methyltransferase. Reaction due to EC 2.1.1.137, arsonite methyltransferase 
                EC 2.1.1.139                      3′-demethylstaurosporine O-methyltransferase 
                EC 2.1.1.140                      (S)-coclaurine-N-methyltransferase 
                EC 2.1.1.141                      jasmonate O-methyltransferase 
                EC 2.1.1.142                      cycloartenol 24-C-methyltransferase 
                EC 2.1.1.143                      24-methylenesterol C-methyltransferase 
                EC 2.1.1.144                      trans-aconitate 2-methyltransferase 
                EC 2.1.1.145                      trans-aconitate 3-methyltransferase 
                EC 2.1.1.146                      (iso)eugenol O-methyltransferase 
                EC 2.1.1.147                      corydaline synthase 
                EC 2.1.1.148                      thymidylate synthase (FAD) 
                EC 2.1.1.149                      myricetin O-methyltransferase. Now covered by EC 2.1.1.267, flavonoid 3′,5′-methyltransferase. 
                EC 2.1.1.150                      isoflavone 7-O-methyltransferase 
                EC 2.1.1.151                      cobalt-factor II C20-methyltransferase 
                EC 2.1.1.152                      precorrin-6A synthase (deacetylating) 
                EC 2.1.1.153                      vitexin 2′′-O-rhamnoside 7-O-methyltransferase 
                EC 2.1.1.154                      isoliquiritigenin 2′-O-methyltransferase 
                EC 2.1.1.155                      kaempferol 4′-O-methyltransferase 
                EC 2.1.1.156                      glycine/sarcosine N-methyltransferase 
                EC 2.1.1.157                      sarcosine/dimethylglycine N-methyltransferase 
                EC 2.1.1.158                      7-methylxanthosine synthase 
                EC 2.1.1.159                      theobromine synthase 
                EC 2.1.1.160                      caffeine synthase 
                EC 2.1.1.161                      dimethylglycine N-methyltransferase 
                EC 2.1.1.162                      glycine/sarcosine/dimethylglycine N-methyltransferase 
                EC 2.1.1.163                      demethylmenaquinone methyltransferase 
                EC 2.1.1.164                      demethylrebeccamycin-D-glucose O-methyltransferase 
                EC 2.1.1.165                      methyl halide transferase 
                EC 2.1.1.166                      23S rRNA (uridine2552-2′-O)-methyltransferase 
                EC 2.1.1.167                      27S pre-rRNA (guanosine2922-2′-O)-methyltransferase 
                EC 2.1.1.168                      21S rRNA (uridine2791-2′-O)-methyltransferase 
                EC 2.1.1.169                      tricetin 3′,4′,5′-O-trimethyltransferase 
                EC 2.1.1.170                      16S rRNA (guanine527-N7)-methyltransferase 
                EC 2.1.1.171                      16S rRNA (guanine966-N2)-methyltransferase 
                EC 2.1.1.172                      16S rRNA (guanine1207-N2)-methyltransferase 
                EC 2.1.1.173                      23S rRNA (guanine2445-N2)-methyltransferase 
                EC 2.1.1.174                      23S rRNA (guanine1835-N2)-methyltransferase 
                EC 2.1.1.175                      tricin synthase 
                EC 2.1.1.176                      16S rRNA (cytosine967-C5)-methyltransferase 
                EC 2.1.1.177                      23S rRNA (pseudouridine1915-N3)-methyltransferase 
                EC 2.1.1.178                      16S rRNA (cytosine1407-C5)-methyltransferase 
                EC 2.1.1.179                      16S rRNA (guanine1405-N7)-methyltransferase 
                EC 2.1.1.180                      16S rRNA (adenine1408-N1)-methyltransferase 
                EC 2.1.1.181                      23S rRNA (adenine1618-N6)-methyltransferase 
                EC 2.1.1.182                      16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase 
                EC 2.1.1.183                      18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase 
                EC 2.1.1.184                      23S rRNA (adenine2085-N6)-dimethyltransferase 
                EC 2.1.1.185                      23S rRNA (guanosine2251-2′-O)-methyltransferase 
                EC 2.1.1.186                      23S rRNA (cytidine2498-2′-O)-methyltransferase 
                EC 2.1.1.187                      23S rRNA (guanine745-N1)-methyltransferase 
                EC 2.1.1.188                      23S rRNA (guanine748-N1)-methyltransferase 
                EC 2.1.1.189                      23S rRNA (uracil747-C5)-methyltransferase 
                EC 2.1.1.190                      23S rRNA (uracil1939-C5)-methyltransferase 
                EC 2.1.1.191                      23S rRNA (cytosine1962-C5)-methyltransferase 
                EC 2.1.1.192                      23S rRNA (adenine2503-C2)-methyltransferase 
                EC 2.1.1.193                      16S rRNA (uracil1498-N3)-methyltransferase 
                EC 2.1.1.194                      23S rRNA (adenine2503-C2,C8)-dimethyltransferase. A mixture of EC 2.1.1.192 (23S rRNA (adenine2503-C2)-methyltransferase) and EC 2.1.1.224 (23S rRNA (adenine2503-C8)-methyltransferase) 
                EC 2.1.1.195                      cobalt-precorrin-5B (C1)-methyltransferase 
                EC 2.1.1.196                      cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating] 
                EC 2.1.1.197                      malonyl-[acyl-carrier protein] O-methyltransferase 
                EC 2.1.1.198                      16S rRNA (cytidine1402-2′-O)-methyltransferase 
                EC 2.1.1.199                      16S rRNA (cytosine1402-N4)-methyltransferase 
                EC 2.1.1.200                      tRNA (cytidine32/uridine32-2′-O)-methyltransferase 
                EC 2.1.1.201                      2-methoxy-6-polyprenyl-1,4-benzoquinol methylase 
                EC 2.1.1.202                      multisite-specific tRNA:(cytosine-C5)-methyltransferase 
                EC 2.1.1.203                      tRNA (cytosine34-C5)-methyltransferase 
                EC 2.1.1.204                      tRNA (cytosine38-C5)-methyltransferase 
                EC 2.1.1.205                      tRNA (cytidine32/guanosine34-2′-O)-methyltransferase 
                EC 2.1.1.206                      tRNA (cytidine56-2′-O)-methyltransferase 
                EC 2.1.1.207                      tRNA (cytidine34-2′-O)-methyltransferase 
                EC 2.1.1.208                      23S rRNA (uridine2479-2′-O)-methyltransferase 
                EC 2.1.1.209                      23S rRNA (guanine2535-N1)-methyltransferase 
                EC 2.1.1.210                      demethylspheroidene O-methyltransferase 
                EC 2.1.1.211                      tRNASer (uridine44-2′-O)-methyltransferase 
                EC 2.1.1.212                      2,7,4′-trihydroxyisoflavanone 4′-O-methyltransferase 
                EC 2.1.1.213                      tRNA (guanine10-N2)-dimethyltransferase 
                EC 2.1.1.214                      tRNA (guanine10-N2)-methyltransferase 
                EC 2.1.1.215                      tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase 
                EC 2.1.1.216                      tRNA (guanine26-N2)-dimethyltransferase 
                EC 2.1.1.217                      tRNA (adenine22-N1)-methyltransferase 
                EC 2.1.1.218                      tRNA (adenine9-N1)-methyltransferase 
                EC 2.1.1.219                      tRNA (adenine57-N1/adenine58-N1)-methyltransferase 
                EC 2.1.1.220                      tRNA (adenine58-N1)-methyltransferase 
                EC 2.1.1.221                      tRNA (guanine9-N1)-methyltransferase 
                EC 2.1.1.222                      2-polyprenyl-6-hydroxyphenol methylase 
                EC 2.1.1.223                      tRNA1Val (adenine37-N6)-methyltransferase 
                EC 2.1.1.224                      23S rRNA (adenine2503-C8)-methyltransferase 
                EC 2.1.1.225                      tRNA:m4X modification enzyme 
                EC 2.1.1.226                      23S rRNA (cytidine1920-2′-O)-methyltransferase 
                EC 2.1.1.227                      16S rRNA (cytidine1409-2′-O)-methyltransferase 
                EC 2.1.1.228                      tRNA (guanine37-N1)-methyltransferase 
                EC 2.1.1.229                      tRNA (carboxymethyluridine34-5-O)-methyltransferase 
                EC 2.1.1.230                      23S rRNA (adenosine1067-2′-O)-methyltransferase 
                EC 2.1.1.231                      flavonoid 4′-O-methyltransferase 
                EC 2.1.1.232                      naringenin 7-O-methyltransferase 
                EC 2.1.1.233                      [phosphatase 2A protein]-leucine-carboxy methyltransferase 
                EC 2.1.1.234                      dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase 
                EC 2.1.1.235                      dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase 
                EC 2.1.1.236                      dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase 
                EC 2.1.1.237                      mycinamicin III 3′′-O-methyltransferase 
                EC 2.1.1.238                      mycinamicin VI 2′′-O-methyltransferase 
                EC 2.1.1.239                      L-olivosyl-oleandolide 3-O-methyltransferase 
                EC 2.1.1.240                      trans-resveratrol di-O-methyltransferase 
                EC 2.1.1.241                      2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase 
                EC 2.1.1.242                      16S rRNA (guanine1516-N2)-methyltransferase 
                EC 2.1.1.243                      2-ketoarginine methyltransferase 
                EC 2.1.1.244                      protein N-terminal methyltransferase 
                EC 2.1.1.245                      5-methyltetrahydrosarcinapterin—corrinoid/iron-sulfur protein Co-methyltransferase 
                EC 2.1.1.246                      [methyl-Co(III) methanol-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.247                      [methyl-Co(III) methylamine-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.248                      methylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.249                      dimethylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.250                      trimethylamine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.251                      methylated-thiol—coenzyme M methyltransferase 
                EC 2.1.1.252                      tetramethylammonium—corrinoid protein Co-methyltransferase 
                EC 2.1.1.253                      [methyl-Co(III) tetramethylammonium-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.254                      erythromycin 3′′-O-methyltransferase 
                EC 2.1.1.255                      geranyl diphosphate 2-C-methyltransferase 
                EC 2.1.1.256                      tRNA (guanine6-N2)-methyltransferase 
                EC 2.1.1.257                      tRNA (pseudouridine54-N1)-methyltransferase 
                EC 2.1.1.258                      5-methyltetrahydrofolate—corrinoid/iron-sulfur protein Co-methyltransferase 
                EC 2.1.1.259                      [fructose-bisphosphate aldolase]-lysine N-methyltransferase 
                EC 2.1.1.260                      rRNA small subunit pseudouridine methyltransferase Nep1 
                EC 2.1.1.261                      4-dimethylallyltryptophan N-methyltransferase 
                EC 2.1.1.262                      squalene methyltransferase 
                EC 2.1.1.263                      botryococcene C-methyltransferase 
                EC 2.1.1.264                      23S rRNA (guanine2069-N7)-methyltransferase 
                EC 2.1.1.265                      tellurite methyltransferase 
                EC 2.1.1.266                      23S rRNA (adenine2030-N6)-methyltransferase 
                EC 2.1.1.267                      flavonoid 3′,5′-methyltransferase 
                EC 2.1.1.268                      tRNAThr (cytosine32-N3)-methyltransferase  
                EC 2.1.1.269                      dimethylsulfoniopropionate demethylase 
                EC 2.1.1.270                      (+)-6a-hydroxymaackiain 3-O-methyltransferase 
                EC 2.1.1.271                      cobalt-precorrin-4 methyltransferase 
                EC 2.1.1.272                      cobalt-factor III methyltransferase 
                EC 2.1.1.273                      benzoate O-methyltransferase 
                EC 2.1.1.274                      salicylate 1-O-methyltransferase 
                EC 2.1.1.275                      gibberellin A9 O-methyltransferase 
                EC 2.1.1.276                      gibberellin A4 carboxyl methyltransferase 
                EC 2.1.1.277                      anthranilate O-methyltransferase 
                EC 2.1.1.278                      indole-3-acetate O-methyltransferase 
                EC 2.1.1.279                      trans-anol O-methyltransferase 
                EC 2.1.1.280                      selenocysteine Se-methyltransferase 
                EC 2.1.1.281                      phenylpyruvate C3-methyltransferase 
                EC 2.1.1.282                      tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase 
                EC 2.1.1.283                      emodin O-methyltransferase 
                EC 2.1.1.284                      8-demethylnovobiocic acid C8-methyltransferase 
                EC 2.1.1.285                      demethyldecarbamoylnovobiocin O-methyltransferase 
                EC 2.1.1.286                      25S rRNA (adenine2142-N1)-methyltransferase 
                EC 2.1.1.287                      25S rRNA (adenine645-N1)-methyltransferase 
                EC 2.1.1.288                      aklanonic acid methyltransferase 
                EC 2.1.1.289                      cobalt-precorrin-7 (C5)-methyltransferase 
                EC 2.1.1.290                      tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase 
                EC 2.1.1.291                      (R,S)-reticuline 7-O-methyltransferase 
                EC 2.1.1.292                      carminomycin 4-O-methyltransferase 
                EC 2.1.1.293                      6-hydroxytryprostatin B O-methyltransferase 
                EC 2.1.1.294                      3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase 
                EC 2.1.1.295                      2-methyl-6-phytyl-1,4-hydroquinone methyltransferase 
                EC 2.1.1.296                      methyltransferase cap2 
                EC 2.1.1.297                      peptide chain release factor N5-glutamine methyltransferase 
                EC 2.1.1.298                      ribosomal protein uL3 N5-glutamine methyltransferase 
                EC 2.1.1.299                      protein N-terminal monomethyltransferase 
                EC 2.1.1.300                      pavine N-methyltransferase 
                EC 2.1.1.301                      cypemycin N-terminal methyltransferase  
                EC 2.1.1.302                      3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase 
                EC 2.1.1.303                      2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase 
                EC 2.1.1.304                      L-tyrosine C3-methyltransferase 
                EC 2.1.1.305                      8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2′-O-methyltransferase 
                EC 2.1.1.306                      8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3′-O-methyltransferase 
                EC 2.1.1.307                      8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4′-O-methyltransferase 
                EC 2.1.1.308                      cytidylyl-2-hydroxyethylphosphonate methyltransferase 
                EC 2.1.1.309                      18S rRNA (guanine1575-N7)-methyltransferase 
                EC 2.1.1.310                      25S rRNA (cytosine2870-C5)-methyltransferase 
                EC 2.1.1.311                      25S rRNA (cytosine2278-C5)-methyltransferase 
                EC 2.1.1.312                      25S rRNA (uracil2843-N3)-methyltransferase 
                EC 2.1.1.313                      25S rRNA (uracil2634-N3)-methyltransferase 
                EC 2.1.1.314                      diphthine methyl ester synthase 
                EC 2.1.1.315                      27-O-demethylrifamycin SV methyltransferase 
                EC 2.1.1.316                      mitomycin 6-O-methyltransferase 
                EC 2.1.1.317                      sphingolipid C9-methyltransferase 
                EC 2.1.1.318                      [trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase 
                EC 2.1.1.319                      type I protein arginine methyltransferase 
                EC 2.1.1.320                      type II protein arginine methyltransferase 
                EC 2.1.1.321                      type III protein arginine methyltransferase 
                EC 2.1.1.322                      type IV protein arginine methyltransferase 
                EC 2.1.1.323                      (–)-pluviatolide 4-O-methyltransferase 
                EC 2.1.1.324                      dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase 
                EC 2.1.1.325                      juvenile hormone-III synthase 
                EC 2.1.1.326                      N-acetyldemethylphosphinothricin P-methyltransferase 
                EC 2.1.1.327                      phenazine-1-carboxylate N-methyltransferase 
                EC 2.1.1.328                      N-demethylindolmycin N-methyltransferase 
                EC 2.1.1.329                      demethylphylloquinol methyltransferase 
                EC 2.1.1.330                      5′-demethylyatein 5′-O-methyltransferase 
                EC 2.1.1.331                      bacteriochlorophyllide d C-121-methyltransferase 
                EC 2.1.1.332                      bacteriochlorophyllide d C-82-methyltransferase 
                EC 2.1.1.333                      bacteriochlorophyllide d C-20 methyltransferase 
                EC 2.1.1.334                      methanethiol S-methyltransferase 
                EC 2.1.1.335                      4-amino-anhydrotetracycline N4-methyltransferase 
                EC 2.1.1.336                      norbelladine O-methyltransferase 
                EC 2.1.1.337                      reticuline N-methyltransferase 
                EC 2.1.1.338                      desmethylxanthohumol 6′-O-methyltransferase 
                EC 2.1.1.339                      xanthohumol 4-O-methyltransferase 
                EC 2.1.1.340                      3-aminomethylindole N-methyltransferase 
                EC 2.1.1.341                      vanillate/3-O-methylgallate O-demethylase 
                EC 2.1.1.342                      anaerobilin synthase 
                EC 2.1.1.343                      8-amino-8-demethylriboflavin N,N-dimethyltransferase 
                EC 2.1.1.344                      ornithine lipid N-methyltransferase 
                EC 2.1.1.345                      psilocybin synthase 
                EC 2.1.1.346                      U6 snRNA m6A methyltransferase 
                EC 2.1.1.347                      (+)-O-methylkolavelool synthase 
                EC 2.1.1.348                      mRNA m6A methyltransferase 
                EC 2.1.1.349                      toxoflavin synthase 
                EC 2.1.1.350                      menaquinone C8-methyltransferase 
                EC 2.1.1.351                      nocamycin O-methyltransferase 
                EC 2.1.1.352                      3-O-acetyl-4′-O-demethylpapaveroxine 4′-O-methyltransferase 
                EC 2.1.1.353                      demethylluteothin O-methyltransferase 
                EC 2.1.1.354                      [histone H3]-lysine4 N-trimethyltransferase 
                EC 2.1.1.355                      [histone H3]-lysine9 N-trimethyltransferase 
                EC 2.1.1.356                      [histone H3]-lysine27 N-trimethyltransferase 
                EC 2.1.1.357                      [histone H3]-lysine36 N-dimethyltransferase 
                EC 2.1.1.358                      [histone H3]-dimethyl-L-lysine36 N-methyltransferase. Now known to have the activity of 2.1.1.359, [histone H3]-lysine36 N-trimethyltransferase. 
                EC 2.1.1.359                      [histone H3]-lysine36 N-trimethyltransferase 
                EC 2.1.1.360                      [histone H3]-lysine79 N-trimethyltransferase 
                EC 2.1.1.361                      [histone H4]-lysine20 N-methyltransferase 
                EC 2.1.1.362                      [histone H4]-N-methyl-L-lysine20 N-methyltransferase 
                EC 2.1.1.363                      pre-sodorifen synthase 
                EC 2.1.1.364                      [histone H3]-lysine4 N-methyltransferase 
                EC 2.1.1.365                      MMP 1-O-methyltransferase 
                EC 2.1.1.366                      [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase 
                EC 2.1.1.367                      [histone H3]-lysine9 N-methyltransferase 
                EC 2.1.1.368                      [histone H3]-lysine9 N-dimethyltransferase 
                EC 2.1.1.369                      [histone H3]-lysine27 N-methyltransferase 
                EC 2.1.1.370                      [histone H3]-lysine4 N-dimethyltransferase 
                EC 2.1.1.371                      [histone H3]-lysine27 N-dimethyltransferase 
                EC 2.1.1.372                      [histone H4]-lysine20 N-trimethyltransferase 
                EC 2.1.1.373                      2-hydroxy-4-(methylsulfanyl)butanoate S-methyltransferase 
                EC 2.1.1.374                      2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase 
                EC 2.1.1.375                      NNS virus cap methyltransferase 
                EC 2.1.1.376                      glycine betaine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.377                      [methyl-Co(III) glycine betaine-specific corrinoid protein]—coenzyme M methyltransferase 
                EC 2.1.1.378                      [methyl-Co(III) glycine betaine-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.379                      [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase 
                EC 2.1.1.380                      3-amino-4-hydroxybenzoate 4-O-methyltransferase 
                EC 2.1.1.381                      arginine Nω-methyltransferase 
                EC 2.1.1.382                      methoxylated aromatic compound—corrinoid protein Co-methyltransferase 
                EC 2.1.1.383                      L-carnitine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.384                      [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]—tetrahydromethanopterin methyltransferase 
                EC 2.1.1.385                      [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.386                      small RNA 2′-O-methyltransferase 
                EC 2.1.1.387                      5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase 
                EC 2.1.1.388                      proline betaine—corrinoid protein Co-methyltransferase 
                EC 2.1.1.389                      [methyl-Co(III) quaternary-amine-specific corrinoid protein]—tetrahydrofolate methyltransferase 
                EC 2.1.1.390                      gentamicin X2 methyltransferase 
                EC 2.1.1.391                      demethylgadusol O-methyltransferase 
        EC 2.1.2       []    Hydroxymethyl-, formyl- and related transferases 
                EC 2.1.2.1                      glycine hydroxymethyltransferase 
                EC 2.1.2.2                      phosphoribosylglycinamide formyltransferase 1 
                EC 2.1.2.3                      phosphoribosylaminoimidazolecarboxamide formyltransferase 
                EC 2.1.2.4                      glycine formimidoyltransferase 
                EC 2.1.2.5                      glutamate formimidoyltransferase 
                EC 2.1.2.6                       glutamate formyltransferase. Now included with EC 2.1.2.5, glutamate formimidoyltransferase 
                EC 2.1.2.7                      D-alanine 2-hydroxymethyltransferase 
                EC 2.1.2.8                      deoxycytidylate 5-hydroxymethyltransferase 
                EC 2.1.2.9                      methionyl-tRNA formyltransferase 
                EC 2.1.2.10                      aminomethyltransferase 
                EC 2.1.2.11                      3-methyl-2-oxobutanoate hydroxymethyltransferase 
                EC 2.1.2.12                       now EC 2.1.1.74 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) 
                EC 2.1.2.13                      UDP-4-amino-4-deoxy-L-arabinose formyltransferase 
                EC 2.1.2.14                      GDP-perosamine N-formyltransferase 
        EC 2.1.3       []    Carboxy- and carbamoyltransferases 
                EC 2.1.3.1                      methylmalonyl-CoA carboxytransferase 
                EC 2.1.3.2                      aspartate carbamoyltransferase 
                EC 2.1.3.3                      ornithine carbamoyltransferase 
                EC 2.1.3.4                       malonyl-CoA carboxyltransferase 
                EC 2.1.3.5                      oxamate carbamoyltransferase 
                EC 2.1.3.6                      putrescine carbamoyltransferase 
                EC 2.1.3.7                      3-hydroxymethylcephem carbamoyltransferase 
                EC 2.1.3.8                      lysine carbamoyltransferase 
                EC 2.1.3.9                      N-acetylornithine carbamoyltransferase 
                EC 2.1.3.10                      malonyl-S-ACP:biotin-protein carboxyltransferase 
                EC 2.1.3.11                      N-succinylornithine carbamoyltransferase 
                EC 2.1.3.12                      decarbamoylnovobiocin carbamoyltransferase 
                EC 2.1.3.13                      ATP carbamoyltransferase. The enzyme has been replaced by EC 6.1.2.2, nebramycin 5′ synthase. 
                EC 2.1.3.14                      tobramycin carbamoyltransferase. The enzyme has been replaced by EC 6.1.2.2, nebramycin 5′ synthase 
                EC 2.1.3.15                      acetyl-CoA carboxytransferase 
                EC 2.1.3.16                      ureidoglycine carbamoyltransferase 
        EC 2.1.4       []    Amidinotransferases 
                EC 2.1.4.1                      glycine amidinotransferase 
                EC 2.1.4.2                      scyllo-inosamine-4-phosphate amidinotransferase 
                EC 2.1.4.3                      L-arginine:L-lysine amidinotransferase 
        EC 2.1.5       []    Methylenetransferases 
                EC 2.1.5.1                      sesamin methylene transferase 
    EC 2.2  [+]      
        EC 2.2.1       []    Transketolases and transaldolases 
                EC 2.2.1.1                      transketolase 
                EC 2.2.1.2                      transaldolase 
                EC 2.2.1.3                      formaldehyde transketolase 
                EC 2.2.1.4                      acetoin—ribose-5-phosphate transaldolase 
                EC 2.2.1.5                      2-hydroxy-3-oxoadipate synthase 
                EC 2.2.1.6                      acetolactate synthase 
                EC 2.2.1.7                      1-deoxy-D-xylulose-5-phosphate synthase 
                EC 2.2.1.8                      fluorothreonine transaldolase 
                EC 2.2.1.9                      2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 
                EC 2.2.1.10                      2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase 
                EC 2.2.1.11                      6-deoxy-5-ketofructose 1-phosphate synthase 
                EC 2.2.1.12                      3-acetyloctanal synthase 
                EC 2.2.1.13                      apulose-4-phosphate transketolase 
                EC 2.2.1.14                      6-deoxy-6-sulfo-D-fructose transaldolase 
                EC 2.2.1.15                      6-deoxy-6-sulfo-D-fructose transketolase 
    EC 2.3  [+]      
        EC 2.3.1       []    Transferring groups other than aminoacyl groups 
                EC 2.3.1.1                      amino-acid N-acetyltransferase 
                EC 2.3.1.2                      imidazole N-acetyltransferase 
                EC 2.3.1.3                      glucosamine N-acetyltransferase 
                EC 2.3.1.4                      glucosamine-phosphate N-acetyltransferase 
                EC 2.3.1.5                      arylamine N-acetyltransferase 
                EC 2.3.1.6                      choline O-acetyltransferase 
                EC 2.3.1.7                      carnitine O-acetyltransferase 
                EC 2.3.1.8                      phosphate acetyltransferase 
                EC 2.3.1.9                      acetyl-CoA C-acetyltransferase 
                EC 2.3.1.10                      hydrogen-sulfide S-acetyltransferase 
                EC 2.3.1.11                      thioethanolamine S-acetyltransferase 
                EC 2.3.1.12                      dihydrolipoyllysine-residue acetyltransferase 
                EC 2.3.1.13                      glycine N-acyltransferase 
                EC 2.3.1.14                      glutamine N-phenylacetyltransferase 
                EC 2.3.1.15                      glycerol-3-phosphate 1-O-acyltransferase 
                EC 2.3.1.16                      acetyl-CoA C-acyltransferase 
                EC 2.3.1.17                      aspartate N-acetyltransferase 
                EC 2.3.1.18                      galactoside O-acetyltransferase 
                EC 2.3.1.19                      phosphate butyryltransferase 
                EC 2.3.1.20                      diacylglycerol O-acyltransferase 
                EC 2.3.1.21                      carnitine O-palmitoyltransferase 
                EC 2.3.1.22                      2-acylglycerol O-acyltransferase 
                EC 2.3.1.23                      1-acylglycerophosphocholine O-acyltransferase 
                EC 2.3.1.24                      sphingosine N-acyltransferase 
                EC 2.3.1.25                      plasmalogen synthase 
                EC 2.3.1.26                      sterol O-acyltransferase 
                EC 2.3.1.27                      cortisol O-acetyltransferase 
                EC 2.3.1.28                      chloramphenicol O-acetyltransferase 
                EC 2.3.1.29                      glycine C-acetyltransferase 
                EC 2.3.1.30                      serine O-acetyltransferase 
                EC 2.3.1.31                      homoserine O-acetyltransferase 
                EC 2.3.1.32                      lysine N-acetyltransferase 
                EC 2.3.1.33                      histidine N-acetyltransferase 
                EC 2.3.1.34                      D-tryptophan N-acetyltransferase 
                EC 2.3.1.35                      glutamate N-acetyltransferase 
                EC 2.3.1.36                      D-amino-acid N-acetyltransferase 
                EC 2.3.1.37                      5-aminolevulinate synthase 
                EC 2.3.1.38                      [acyl-carrier-protein] S-acetyltransferase 
                EC 2.3.1.39                      [acyl-carrier-protein] S-malonyltransferase 
                EC 2.3.1.40                      acyl-[acyl-carrier-protein]—phospholipid O-acyltransferase 
                EC 2.3.1.41                      β-ketoacyl-[acyl-carrier-protein] synthase I 
                EC 2.3.1.42                      glycerone-phosphate O-acyltransferase 
                EC 2.3.1.43                      phosphatidylcholine—sterol O-acyltransferase 
                EC 2.3.1.44                      N-acetylneuraminate 4-O-acetyltransferase 
                EC 2.3.1.45                      N-acetylneuraminate 7-O(or 9-O)-acetyltransferase 
                EC 2.3.1.46                      homoserine O-succinyltransferase 
                EC 2.3.1.47                      8-amino-7-oxononanoate synthase 
                EC 2.3.1.48                      histone acetyltransferase 
                EC 2.3.1.49                      deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase 
                EC 2.3.1.50                      serine C-palmitoyltransferase 
                EC 2.3.1.51                      1-acylglycerol-3-phosphate O-acyltransferase 
                EC 2.3.1.52                      2-acylglycerol-3-phosphate O-acyltransferase 
                EC 2.3.1.53                      phenylalanine N-acetyltransferase 
                EC 2.3.1.54                      formate C-acetyltransferase 
                EC 2.3.1.55                       kanamycin 6′-N-acetyltransferase identical to EC 2.3.1.82 aminoglycoside N6′-acetyltransferase 
                EC 2.3.1.56                      aromatic-hydroxylamine O-acetyltransferase 
                EC 2.3.1.57                      diamine N-acetyltransferase 
                EC 2.3.1.58                      2,3-diaminopropionate N-oxalyltransferase 
                EC 2.3.1.59                      gentamicin 2′-N-acetyltransferase 
                EC 2.3.1.60                      gentamicin 3-N-acetyltransferase 
                EC 2.3.1.61                      dihydrolipoyllysine-residue succinyltransferase 
                EC 2.3.1.62                      2-acylglycerophosphocholine O-acyltransferase 
                EC 2.3.1.63                      1-alkylglycerophosphocholine O-acyltransferase 
                EC 2.3.1.64                      agmatine N4-coumaroyltransferase 
                EC 2.3.1.65                      bile acid-CoA:amino acid N-acyltransferase 
                EC 2.3.1.66                      leucine N-acetyltransferase 
                EC 2.3.1.67                      1-alkylglycerophosphocholine O-acetyltransferase 
                EC 2.3.1.68                      glutamine N-acyltransferase 
                EC 2.3.1.69                      monoterpenol O-acetyltransferase 
                EC 2.3.1.70                      CDP-acylglycerol O-arachidonoyltransferase. This enzyme was deleted following a retraction of the evidence upon which the entry had been drafted (Thompson, W. and Zuk, R.T. Acylation of CDP-monoacylglycerol cannot be confirmed. J. Biol. Chem. 258 (1983) 9623. [PMID: 6885763]). 
                EC 2.3.1.71                      glycine N-benzoyltransferase 
                EC 2.3.1.72                      indoleacetylglucose—inositol O-acyltransferase 
                EC 2.3.1.73                      diacylglycerol—sterol O-acyltransferase 
                EC 2.3.1.74                      chalcone synthase 
                EC 2.3.1.75                      long-chain-alcohol O-fatty-acyltransferase 
                EC 2.3.1.76                      retinol O-fatty-acyltransferase 
                EC 2.3.1.77                      triacylglycerol—sterol O-acyltransferase 
                EC 2.3.1.78                      heparan-α-glucosaminide N-acetyltransferase 
                EC 2.3.1.79                      maltose O-acetyltransferase 
                EC 2.3.1.80                      cysteine-S-conjugate N-acetyltransferase 
                EC 2.3.1.81                      aminoglycoside 3-N-acetyltransferase 
                EC 2.3.1.82                      aminoglycoside 6′-N-acetyltransferase 
                EC 2.3.1.83                      phosphatidylcholine—dolichol O-acyltransferase 
                EC 2.3.1.84                      alcohol O-acetyltransferase 
                EC 2.3.1.85                      fatty-acid synthase system 
                EC 2.3.1.86                      fatty-acyl-CoA synthase system 
                EC 2.3.1.87                      aralkylamine N-acetyltransferase 
                EC 2.3.1.88                      peptide α-N-acetyltransferase. Now covered by EC 2.3.1.254, N-terminal methionine Nα-acetyltransferase NatB, EC 2.3.1.255, N-terminal amino-acid Nα-acetyltransferase NatA, EC 2.3.1.256, N-terminal methionine Nα-acetyltransferase NatC, EC 2.3.1.257, N-terminal L-serine Nα-acetyltransferase NatD, EC 2.3.1.258, N-terminal methionine Nα-acetyltransferase NatE and EC 2.3.1.259, N-terminal methionine Nα-acetyltransferase NatF 
                EC 2.3.1.89                      tetrahydrodipicolinate N-acetyltransferase 
                EC 2.3.1.90                      β-glucogallin O-galloyltransferase 
                EC 2.3.1.91                      sinapoylglucose—choline O-sinapoyltransferase 
                EC 2.3.1.92                      sinapoylglucose—malate O-sinapoyltransferase 
                EC 2.3.1.93                      13-hydroxylupanine O-tigloyltransferase 
                EC 2.3.1.94                      6-deoxyerythronolide-B synthase 
                EC 2.3.1.95                      trihydroxystilbene synthase 
                EC 2.3.1.96                      glycoprotein N-palmitoyltransferase 
                EC 2.3.1.97                      glycylpeptide N-tetradecanoyltransferase 
                EC 2.3.1.98                      chlorogenate—glucarate O-hydroxycinnamoyltransferase 
                EC 2.3.1.99                      quinate O-hydroxycinnamoyltransferase 
                EC 2.3.1.100                      [myelin-proteolipid] O-palmitoyltransferase 
                EC 2.3.1.101                      formylmethanofuran—tetrahydromethanopterin N-formyltransferase 
                EC 2.3.1.102                      N6-hydroxylysine N-acetyltransferase 
                EC 2.3.1.103                      sinapoylglucose—sinapoylglucose O-sinapoyltransferase 
                EC 2.3.1.104                      1-alkenylglycerophosphocholine O-acyltransferase. The activity is covered by EC 2.3.1.25, plasmalogen synthase 
                EC 2.3.1.105                      alkylglycerophosphate 2-O-acetyltransferase 
                EC 2.3.1.106                      tartronate O-hydroxycinnamoyltransferase 
                EC 2.3.1.107                      deacetylvindoline O-acetyltransferase 
                EC 2.3.1.108                      α-tubulin N-acetyltransferase 
                EC 2.3.1.109                      arginine N-succinyltransferase 
                EC 2.3.1.110                      tyramine N-feruloyltransferase 
                EC 2.3.1.111                      mycocerosate synthase 
                EC 2.3.1.112                      D-tryptophan N-malonyltransferase 
                EC 2.3.1.113                      anthranilate N-malonyltransferase 
                EC 2.3.1.114                      3,4-dichloroaniline N-malonyltransferase 
                EC 2.3.1.115                      isoflavone-7-O-β-glucoside 6′′-O-malonyltransferase 
                EC 2.3.1.116                      flavonol-3-O-β-glucoside O-malonyltransferase 
                EC 2.3.1.117                      2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 
                EC 2.3.1.118                      N-hydroxyarylamine O-acetyltransferase 
                EC 2.3.1.119                      icosanoyl-CoA synthase. Now covered by EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. 
                EC 2.3.1.120                       6′-deoxychalcone synthase. The reaction listed is due to EC 2.3.1.74 naringenin-chalcone synthase 
                EC 2.3.1.121                      1-alkenylglycerophosphoethanolamine O-acyltransferase 
                EC 2.3.1.122                      trehalose O-mycolyltransferase 
                EC 2.3.1.123                      dolichol O-acyltransferase 
                EC 2.3.1.124                      diacylglycerol acyltransferase. Already listed as EC 2.3.1.20, diacylglycerol O-acyltransferase 
                EC 2.3.1.125                      1-alkyl-2-acetylglycerol O-acyltransferase 
                EC 2.3.1.126                      isocitrate O-dihydroxycinnamoyltransferase 
                EC 2.3.1.127                      ornithine N-benzoyltransferase 
                EC 2.3.1.128                      ribosomal-protein-alanine N-acetyltransferase, now classified as EC 2.3.1.266, [ribosomal protein S18]-alanine N-acetyltransferase, and EC 2.3.1.267, [ribosomal protein S5]-alanine N-acetyltransferase.  
                EC 2.3.1.129                      acyl-[acyl-carrier-protein]—UDP-N-acetylglucosamine O-acyltransferase 
                EC 2.3.1.130                      galactarate O-hydroxycinnamoyltransferase 
                EC 2.3.1.131                      glucarate O-hydroxycinnamoyltransferase 
                EC 2.3.1.132                      glucarolactone O-hydroxycinnamoyltransferase 
                EC 2.3.1.133                      shikimate O-hydroxycinnamoyltransferase 
                EC 2.3.1.134                      galactolipid O-acyltransferase 
                EC 2.3.1.135                      phosphatidylcholine—retinol O-acyltransferase 
                EC 2.3.1.136                      polysialic-acid O-acetyltransferase 
                EC 2.3.1.137                      carnitine O-octanoyltransferase 
                EC 2.3.1.138                      putrescine N-hydroxycinnamoyltransferase 
                EC 2.3.1.139                      ecdysone O-acyltransferase 
                EC 2.3.1.140                      rosmarinate synthase 
                EC 2.3.1.141                      galactosylacylglycerol O-acyltransferase 
                EC 2.3.1.142                      glycoprotein O-fatty-acyltransferase 
                EC 2.3.1.143                      β-glucogallin—tetrakisgalloylglucose O-galloyltransferase 
                EC 2.3.1.144                      anthranilate N-benzoyltransferase 
                EC 2.3.1.145                      piperidine N-piperoyltransferase 
                EC 2.3.1.146                      pinosylvin synthase 
                EC 2.3.1.147                      glycerophospholipid arachidonoyl-transferase (CoA-independent) 
                EC 2.3.1.148                      glycerophospholipid acyltransferase (CoA-dependent) 
                EC 2.3.1.149                      platelet-activating factor acetyltransferase 
                EC 2.3.1.150                      salutaridinol 7-O-acetyltransferase 
                EC 2.3.1.151                      2,3′,4,6-tetrahydroxybenzophenone synthase 
                EC 2.3.1.152                      alcohol O-cinnamoyltransferase 
                EC 2.3.1.153                      anthocyanin 5-(6′′′-hydroxycinnamoyltransferase) 
                EC 2.3.1.154                      Propionyl-CoA C2-trimethyltridecanoyltransferase. Now EC 2.3.1.176, propanoyl-CoA C-acyltransferase. 
                EC 2.3.1.155                      acetyl-CoA C-myristoyltransferase 
                EC 2.3.1.156                      phloroisovalerophenone synthase 
                EC 2.3.1.157                      glucosamine-1-phosphate N-acetyltransferase 
                EC 2.3.1.158                      phospholipid:diacylglycerol acyltransferase 
                EC 2.3.1.159                      acridone synthase 
                EC 2.3.1.160                      vinorine synthase 
                EC 2.3.1.161                      lovastatin nonaketide synthase 
                EC 2.3.1.162                      taxadien-5α-ol O-acetyltransferase 
                EC 2.3.1.163                      10-hydroxytaxane O-acetyltransferase 
                EC 2.3.1.164                      isopenicillin-N N-acyltransferase 
                EC 2.3.1.165                      6-methylsalicylic-acid synthase 
                EC 2.3.1.166                      2α-hydroxytaxane 2-O-benzoyltransferase 
                EC 2.3.1.167                      10-deacetylbaccatin III 10-O-acetyltransferase 
                EC 2.3.1.168                      dihydrolipoyllysine-residue (2-methylpropanoyl)transferase 
                EC 2.3.1.169                      CO-methylating acetyl-CoA synthase 
                EC 2.3.1.170                      6′-deoxychalcone synthase 
                EC 2.3.1.171                      anthocyanin 6′′-O-malonyltransferase 
                EC 2.3.1.172                      anthocyanin 5-O-glucoside 6′′′-O-malonyltransferase 
                EC 2.3.1.173                      flavonol-3-O-triglucoside O-coumaroyltransferase 
                EC 2.3.1.174                      3-oxoadipyl-CoA thiolase 
                EC 2.3.1.175                      deacetylcephalosporin-C acetyltransferase 
                EC 2.3.1.176                      propanoyl-CoA C-acyltransferase 
                EC 2.3.1.177                      3,5-dihydroxybiphenyl synthase 
                EC 2.3.1.178                      diaminobutyrate acetyltransferase 
                EC 2.3.1.179                      β-ketoacyl-[acyl-carrier-protein] synthase II 
                EC 2.3.1.180                      β-ketoacyl-[acyl-carrier-protein] synthase III 
                EC 2.3.1.181                      lipoyl(octanoyl) transferase 
                EC 2.3.1.182                      (R)-citramalate synthase. Now classified as EC 2.3.3.21, (R)-citramalate synthase. 
                EC 2.3.1.183                      phosphinothricin acetyltransferase 
                EC 2.3.1.184                      acyl-homoserine-lactone synthase 
                EC 2.3.1.185                      tropine acyltransferase 
                EC 2.3.1.186                      pseudotropine acyltransferase 
                EC 2.3.1.187                      acetyl-S-ACP:malonate ACP transferase 
                EC 2.3.1.188                      ω-hydroxypalmitate O-feruloyl transferase 
                EC 2.3.1.189                      mycothiol synthase 
                EC 2.3.1.190                      acetoin dehydrogenase system 
                EC 2.3.1.191                      UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase 
                EC 2.3.1.192                      glycine N-phenylacetyltransferase 
                EC 2.3.1.193                      tRNAMet cytidine acetyltransferase 
                EC 2.3.1.194                      acetoacetyl-CoA synthase 
                EC 2.3.1.195                      (Z)-3-hexen-1-ol acetyltransferase 
                EC 2.3.1.196                      benzyl alcohol O-benzoyltransferase 
                EC 2.3.1.197                      dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose 3-N-acetyltransferase 
                EC 2.3.1.198                      glycerol-3-phosphate 2-O-acyltransferase 
                EC 2.3.1.199                      very-long-chain 3-oxoacyl-CoA synthase 
                EC 2.3.1.200                      lipoyl amidotransferase 
                EC 2.3.1.201                      UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase 
                EC 2.3.1.202                      UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine N-acetyltransferase  
                EC 2.3.1.203                      UDP-N-acetylbacillosamine N-acetyltransferase 
                EC 2.3.1.204                      octanoyl-[GcvH]:protein N-octanoyltransferase 
                EC 2.3.1.205                      fumigaclavine B O-acetyltransferase 
                EC 2.3.1.206                      3,5,7-trioxododecanoyl-CoA synthase 
                EC 2.3.1.207                      β-ketodecanoyl-[acyl-carrier-protein] synthase 
                EC 2.3.1.208                      4-hydroxycoumarin synthase 
                EC 2.3.1.209                      dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase 
                EC 2.3.1.210                      dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase 
                EC 2.3.1.211                      bisdemethoxycurcumin synthase 
                EC 2.3.1.212                      benzalacetone synthase 
                EC 2.3.1.213                      cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) 6′′′-O-hydroxycinnamoyltransferase 
                EC 2.3.1.214                      pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4′′′-malonyltransferase 
                EC 2.3.1.215                      anthocyanidin 3-O-glucoside 6′′-O-acyltransferase  
                EC 2.3.1.216                      5,7-dihydroxy-2-methylchromone synthase 
                EC 2.3.1.217                      curcumin synthase 
                EC 2.3.1.218                      phenylpropanoylacetyl-CoA synthase 
                EC 2.3.1.219                      demethoxycurcumin synthase 
                EC 2.3.1.220                      2,4,6-trihydroxybenzophenone synthase 
                EC 2.3.1.221                      noranthrone synthase 
                EC 2.3.1.222                      phosphate propanoyltransferase 
                EC 2.3.1.223                      3-oxo-5,6-didehydrosuberyl-CoA thiolase  
                EC 2.3.1.224                      acetyl-CoA-benzylalcohol acetyltransferase 
                EC 2.3.1.225                      protein S-acyltransferase  
                EC 2.3.1.226                      carboxymethylproline synthase 
                EC 2.3.1.227                      GDP-perosamine N-acetyltransferase 
                EC 2.3.1.228                      isovaleryl-homoserine lactone synthase 
                EC 2.3.1.229                      4-coumaroyl-homoserine lactone synthase 
                EC 2.3.1.230                      2-heptyl-4(1H)-quinolone synthase 
                EC 2.3.1.231                      tRNAPhe {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methoxycarbonyltransferase 
                EC 2.3.1.232                      methanol O-anthraniloyltransferase 
                EC 2.3.1.233                      1,3,6,8-tetrahydroxynaphthalene synthase 
                EC 2.3.1.234                      N6-L-threonylcarbamoyladenine synthase 
                EC 2.3.1.235                      tetracenomycin F2 synthase 
                EC 2.3.1.236                      5-methylnaphthoic acid synthase 
                EC 2.3.1.237                      neocarzinostatin naphthoate synthase 
                EC 2.3.1.238                      monacolin J acid methylbutanoate transferase 
                EC 2.3.1.239                      10-deoxymethynolide synthase 
                EC 2.3.1.240                      narbonolide synthase 
                EC 2.3.1.241                      Kdo2-lipid IVA acyltransferase 
                EC 2.3.1.242                      Kdo2-lipid IVA palmitoleoyltransferase 
                EC 2.3.1.243                      acyl-Kdo2-lipid IVA acyltransferase 
                EC 2.3.1.244                      2-methylbutanoate polyketide synthase 
                EC 2.3.1.245                      3-hydroxy-5-phosphooxypentane-2,4-dione thiolase 
                EC 2.3.1.246                      3,5-dihydroxyphenylacetyl-CoA synthase 
                EC 2.3.1.247                      3-keto-5-aminohexanoate cleavage enzyme 
                EC 2.3.1.248                      spermidine disinapoyl transferase 
                EC 2.3.1.249                      spermidine dicoumaroyl transferase 
                EC 2.3.1.250                      [Wnt protein] O-palmitoleoyl transferase 
                EC 2.3.1.251                      lipid IVA palmitoyltransferase 
                EC 2.3.1.252                      mycolipanoate synthase 
                EC 2.3.1.253                      phloroglucinol synthase 
                EC 2.3.1.254                      N-terminal methionine Nα-acetyltransferase NatB 
                EC 2.3.1.255                      N-terminal amino-acid Nα-acetyltransferase NatA 
                EC 2.3.1.256                      N-terminal methionine Nα-acetyltransferase NatC 
                EC 2.3.1.257                      N-terminal L-serine Nα-acetyltransferase NatD 
                EC 2.3.1.258                      N-terminal methionine Nα-acetyltransferase NatE 
                EC 2.3.1.259                      N-terminal methionine Nα-acetyltransferase NatF 
                EC 2.3.1.260                      tetracycline polyketide synthase 
                EC 2.3.1.261                      (4-hydroxyphenyl)alkanoate synthase 
                EC 2.3.1.262                      anthraniloyl-CoA anthraniloyltransferase 
                EC 2.3.1.263                      2-amino-4-oxopentanoate thiolase 
                EC 2.3.1.264                      β-lysine N6-acetyltransferase 
                EC 2.3.1.265                      phosphatidylinositol dimannoside acyltransferase 
                EC 2.3.1.266                      [ribosomal protein bS18]-alanine N-acetyltransferase 
                EC 2.3.1.267                      [ribosomal protein uS5]-alanine N-acetyltransferase 
                EC 2.3.1.268                      ethanol O-acetyltransferase 
                EC 2.3.1.269                      apolipoprotein N-acyltransferase 
                EC 2.3.1.270                      lyso-ornithine lipid O-acyltransferase 
                EC 2.3.1.271                      L-glutamate-5-semialdehyde N-acetyltransferase 
                EC 2.3.1.272                      2-acetylphloroglucinol acetyltransferase 
                EC 2.3.1.273                      diglucosylglycerate octanoyltransferase 
                EC 2.3.1.274                      phosphate acyltransferase 
                EC 2.3.1.275                      acyl phosphate:glycerol-3-phosphate acyltransferase 
                EC 2.3.1.276                      galactosamine-1-phosphate N-acetyltransferase 
                EC 2.3.1.277                      2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase 
                EC 2.3.1.278                      mycolipenoyl-CoA—2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase 
                EC 2.3.1.279                      long-chain-acyl-CoA—trehalose acyltransferase 
                EC 2.3.1.280                      (aminoalkyl)phosphonate N-acetyltransferase 
                EC 2.3.1.281                      5-hydroxydodecatetraenal polyketide synthase 
                EC 2.3.1.282                      phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase 
                EC 2.3.1.283                      2′-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase 
                EC 2.3.1.284                      3′-(hydroxy)phthioceranyl-2′-palmitoyl(stearoyl)-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase 
                EC 2.3.1.285                      (13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase 
                EC 2.3.1.286                      protein acetyllysine N-acetyltransferase 
                EC 2.3.1.287                      phthioceranic/hydroxyphthioceranic acid synthase 
                EC 2.3.1.288                      2-O-sulfo trehalose long-chain-acyltransferase 
                EC 2.3.1.289                      aureothin polyketide synthase system 
                EC 2.3.1.290                      spectinabilin polyketide synthase system 
                EC 2.3.1.291                      sphingoid base N-palmitoyltransferase 
                EC 2.3.1.292                      (phenol)carboxyphthiodiolenone synthase 
                EC 2.3.1.293                      meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I 
                EC 2.3.1.294                      meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II 
                EC 2.3.1.295                      mycoketide-CoA synthase 
                EC 2.3.1.296                      ω-hydroxyceramide transacylase 
                EC 2.3.1.297                      very-long-chain ceramide synthase 
                EC 2.3.1.298                      ultra-long-chain ceramide synthase 
                EC 2.3.1.299                      sphingoid base N-stearoyltransferase 
                EC 2.3.1.300                      branched-chain β-ketoacyl-[acyl-carrier-protein] synthase 
                EC 2.3.1.301                      mycobacterial β-ketoacyl-[acyl carrier protein] synthase III 
                EC 2.3.1.302                      hydroxycinnamoyl-CoA:5-hydroxyanthranilate N-hydroxycinnamoyltransferase 
                EC 2.3.1.303                      α-L-Rha-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-α-D-Gal-PP-Und 2IV-O-acetyltransferase 
                EC 2.3.1.304                      poly[(R)-3-hydroxyalkanoate] polymerase 
                EC 2.3.1.305                      acyl-[acyl-carrier protein]—UDP-2-acetamido-3-amino-2,3-dideoxy-α-D-glucopyranose N-acyltransferase 
                EC 2.3.1.306                      acetyl-CoA:lysine N6-acetyltransferase 
                EC 2.3.1.307                      6-diazo-5-oxo-L-norleucine Nα-acetyltranferase 
                EC 2.3.1.308                      tubulin N-terminal N-acetyltransferase NAT9 
                EC 2.3.1.309                      [β-tubulin]-L-lysine N-acetyltransferase 
                EC 2.3.1.310                      benzoylsuccinyl-CoA thiolase 
                EC 2.3.1.311                      tRNA carboxymethyluridine synthase 
                EC 2.3.1.312                      D-glutamate N-acetyltransferase 
                EC 2.3.1.313                      NAD-dependent lipoamidase 
        EC 2.3.2       []    Aminoacyltransferases 
                EC 2.3.2.1                      D-glutamyltransferase 
                EC 2.3.2.2                      γ-glutamyltransferase 
                EC 2.3.2.3                      lysyltransferase 
                EC 2.3.2.4                      γ-glutamylcyclotransferase. Now classified as EC 4.3.2.9, γ-glutamylcyclotransferase 
                EC 2.3.2.5                      glutaminyl-peptide cyclotransferase 
                EC 2.3.2.6                      lysine/arginine leucyltransferase 
                EC 2.3.2.7                      aspartyltransferase 
                EC 2.3.2.8                      arginyltransferase 
                EC 2.3.2.9                      agaritine γ-glutamyltransferase 
                EC 2.3.2.10                      UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase 
                EC 2.3.2.11                      alanylphosphatidylglycerol synthase 
                EC 2.3.2.12                      peptidyltransferase 
                EC 2.3.2.13                      protein-glutamine γ-glutamyltransferase 
                EC 2.3.2.14                      D-alanine γ-glutamyltransferase 
                EC 2.3.2.15                      glutathione γ-glutamylcysteinyltransferase 
                EC 2.3.2.16                      lipid II:glycine glycyltransferase 
                EC 2.3.2.17                      N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase 
                EC 2.3.2.18                      N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase 
                EC 2.3.2.19                      ribostamycin:4-(γ-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] 4-(γ-L-glutamylamino)-(S)-2-hydroxybutanoate transferase 
                EC 2.3.2.20                      cyclo(L-leucyl-L-phenylalanyl) synthase 
                EC 2.3.2.21                      cyclo(L-tyrosyl-L-tyrosyl) synthase 
                EC 2.3.2.22                      cyclo(L-leucyl-L-leucyl) synthase 
                EC 2.3.2.23                      E2 ubiquitin-conjugating enzyme 
                EC 2.3.2.24                      (E3-independent) E2 ubiquitin-conjugating enzyme 
                EC 2.3.2.25                      N-terminal E2 ubiquitin-conjugating enzyme 
                EC 2.3.2.26                      HECT-type E3 ubiquitin transferase 
                EC 2.3.2.27                      RING-type E3 ubiquitin transferase 
                EC 2.3.2.28                      L-allo-isoleucyltransferase 
                EC 2.3.2.29                      aspartate/glutamate leucyltransferase 
                EC 2.3.2.30                      L-ornithine Nα-acyltransferase 
                EC 2.3.2.31                      RBR-type E3 ubiquitin transferase 
                EC 2.3.2.32                      cullin-RING-type E3 NEDD8 transferase 
                EC 2.3.2.33                      RCR-type E3 ubiquitin transferase 
                EC 2.3.2.34                      E2 NEDD8-conjugating enzyme 
                EC 2.3.2.35                      capsaicin synthase 
                EC 2.3.2.36                      RING-type E3 ubiquitin transferase (cysteine targeting) 
                EC 2.3.2.37                      ergosteryl-3β-O-L-aspartate synthase 
        EC 2.3.3       []    Acyl groups converted into alkyl groups on transfer 
                EC 2.3.3.1                      citrate (Si)-synthase 
                EC 2.3.3.2                      decylcitrate synthase 
                EC 2.3.3.3                      citrate (Re)-synthase 
                EC 2.3.3.4                      decylhomocitrate synthase 
                EC 2.3.3.5                      2-methylcitrate synthase 
                EC 2.3.3.6                      2-ethylmalate synthase 
                EC 2.3.3.7                      3-ethylmalate synthase 
                EC 2.3.3.8                      ATP citrate synthase 
                EC 2.3.3.9                      malate synthase 
                EC 2.3.3.10                      hydroxymethylglutaryl-CoA synthase 
                EC 2.3.3.11                      2-hydroxyglutarate synthase 
                EC 2.3.3.12                      3-propylmalate synthase 
                EC 2.3.3.13                      2-isopropylmalate synthase 
                EC 2.3.3.14                      homocitrate synthase 
                EC 2.3.3.15                      sulfoacetaldehyde acetyltransferase 
                EC 2.3.3.16                      citrate synthase (unknown stereospecificity) 
                EC 2.3.3.17                      methylthioalkylmalate synthase 
                EC 2.3.3.18                      2-phosphinomethylmalate synthase 
                EC 2.3.3.19                      2-phosphonomethylmalate synthase 
                EC 2.3.3.20                      acyl-CoA:acyl-CoA alkyltransferase 
                EC 2.3.3.21                      (R)-citramalate synthase 
                EC 2.3.3.22                      3-carboxymethyl-3-hydroxy-acyl-[acp] synthase 
    EC 2.4  [+]      
        EC 2.4.1       []    Hexosyltransferases 
                EC 2.4.1.1                      glycogen phosphorylase 
                EC 2.4.1.2                      dextrin dextranase 
                EC 2.4.1.3                       amylomaltase. Now included with EC 2.4.1.25, 4-α-glucanotransferase 
                EC 2.4.1.4                      amylosucrase 
                EC 2.4.1.5                      dextransucrase 
                EC 2.4.1.6                       maltose 3-glycosyltransferase 
                EC 2.4.1.7                      sucrose phosphorylase 
                EC 2.4.1.8                      maltose phosphorylase 
                EC 2.4.1.9                      inulosucrase 
                EC 2.4.1.10                      levansucrase 
                EC 2.4.1.11                      glycogen(starch) synthase 
                EC 2.4.1.12                      cellulose synthase (UDP-forming) 
                EC 2.4.1.13                      sucrose synthase 
                EC 2.4.1.14                      sucrose-phosphate synthase 
                EC 2.4.1.15                      α,α-trehalose-phosphate synthase (UDP-forming) 
                EC 2.4.1.16                      chitin synthase 
                EC 2.4.1.17                      glucuronosyltransferase 
                EC 2.4.1.18                      1,4-α-glucan branching enzyme 
                EC 2.4.1.19                      cyclomaltodextrin glucanotransferase 
                EC 2.4.1.20                      cellobiose phosphorylase 
                EC 2.4.1.21                      starch synthase (glycosyl-transferring) 
                EC 2.4.1.22                      lactose synthase 
                EC 2.4.1.23                      sphingosine β-galactosyltransferase 
                EC 2.4.1.24                      1,4-α-glucan 6-α-glucosyltransferase 
                EC 2.4.1.25                      4-α-glucanotransferase 
                EC 2.4.1.26                      DNA α-glucosyltransferase 
                EC 2.4.1.27                      DNA β-glucosyltransferase 
                EC 2.4.1.28                      glucosyl-DNA β-glucosyltransferase 
                EC 2.4.1.29                      cellulose synthase (GDP-forming) 
                EC 2.4.1.30                      1,3-β-oligoglucan phosphorylase 
                EC 2.4.1.31                      laminaribiose phosphorylase 
                EC 2.4.1.32                      glucomannan 4-β-mannosyltransferase 
                EC 2.4.1.33                      mannuronan synthase 
                EC 2.4.1.34                      1,3-β-glucan synthase 
                EC 2.4.1.35                      phenol β-glucosyltransferase 
                EC 2.4.1.36                      α,α-trehalose-phosphate synthase (GDP-forming) 
                EC 2.4.1.37                      fucosylgalactoside 3-α-galactosyltransferase 
                EC 2.4.1.38                      β-N-acetylglucosaminylglycopeptide β-1,4-galactosyltransferase 
                EC 2.4.1.39                      steroid N-acetylglucosaminyltransferase 
                EC 2.4.1.40                      glycoprotein-fucosylgalactoside α-N-acetylgalactosaminyltransferase 
                EC 2.4.1.41                      polypeptide N-acetylgalactosaminyltransferase 
                EC 2.4.1.42                       UDP-glucuronate—estriol 17β-D-glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.43                      polygalacturonate 4-α-galacturonosyltransferase 
                EC 2.4.1.44                      lipopolysaccharide 3-α-galactosyltransferase 
                EC 2.4.1.45                      2-hydroxyacylsphingosine 1-β-galactosyltransferase, now included with EC 2.4.1.47, N-acylsphingosine galactosyltransferase 
                EC 2.4.1.46                      monogalactosyldiacylglycerol synthase 
                EC 2.4.1.47                      N-acylsphingosine galactosyltransferase 
                EC 2.4.1.48                      heteroglycan α-mannosyltransferase 
                EC 2.4.1.49                      cellodextrin phosphorylase 
                EC 2.4.1.50                      procollagen galactosyltransferase 
                EC 2.4.1.51                       UDP-N-acetylglucosamine—glycoprotein N-acetylglucosaminyltransferase. Now listed as EC 2.4.1.101 (α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase), EC 2.4.1.143 (α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase), EC 2.4.1.144 (β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase) and EC 2.4.1.145 (α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase) 
                EC 2.4.1.52                      poly(glycerol-phosphate) α-glucosyltransferase 
                EC 2.4.1.53                      poly(ribitol-phosphate) β-glucosyltransferase 
                EC 2.4.1.54                      undecaprenyl-phosphate mannosyltransferase 
                EC 2.4.1.55                      teichoic-acid synthase. Now EC 2.7.8.14, CDP-ribitol ribitolphosphotransferase 
                EC 2.4.1.56                      lipopolysaccharide N-acetylglucosaminyltransferase 
                EC 2.4.1.57                      phosphatidylinositol α-mannosyltransferase. Newer studies have shown that this is catalysed by two independent activities now covered by EC 2.4.1.345, phosphatidyl-myo-inositol α-mannosyl transferase and EC 2.4.1.346, phosphatidyl-myo-inositol dimannoside synthase 
                EC 2.4.1.58                      lipopolysaccharide glucosyltransferase I 
                EC 2.4.1.59                       UDP-glucuronate—estradiol glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.60                      CDP-abequose:α-D-Man-(1→4)-α-L-Rha-(1→3)-α-D-Gal-PP-Und α-1,3-abequosyltransferase 
                EC 2.4.1.61                       UDP-glucuronate—estriol 16α-glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.62                      ganglioside galactosyltransferase 
                EC 2.4.1.63                      linamarin synthase 
                EC 2.4.1.64                      α,α-trehalose phosphorylase 
                EC 2.4.1.65                      3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase 
                EC 2.4.1.66                      procollagen glucosyltransferase 
                EC 2.4.1.67                      galactinol—raffinose galactosyltransferase 
                EC 2.4.1.68                      glycoprotein 6-α-L-fucosyltransferase 
                EC 2.4.1.69                      type 1 galactoside α-(1,2)-fucosyltransferase 
                EC 2.4.1.70                      poly(ribitol-phosphate) α-N-acetylglucosaminyltransferase 
                EC 2.4.1.71                      arylamine glucosyltransferase 
                EC 2.4.1.72                      1,4-β-xylan synthase. Now EC 2.4.2.24, 1,4-β-D-xylan synthase 
                EC 2.4.1.73                      lipopolysaccharide glucosyltransferase II 
                EC 2.4.1.74                      glycosaminoglycan galactosyltransferase 
                EC 2.4.1.75                      UDP-galacturonosyltransferase. Insufficient evidence to conclude that this is a different enzyme from EC 2.4.1.43, polygalacturonate 4-α-galacturonosyltransferase 
                EC 2.4.1.76                       UDP-glucuronate—bilirubin glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.77                       UDP-glucuronate—bilirubin-glucuronoside glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.78                      phosphopolyprenol glucosyltransferase 
                EC 2.4.1.79                      globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase 
                EC 2.4.1.80                      ceramide glucosyltransferase 
                EC 2.4.1.81                      flavone 7-O-β-glucosyltransferase 
                EC 2.4.1.82                      galactinol—sucrose galactosyltransferase 
                EC 2.4.1.83                      dolichyl-phosphate β-D-mannosyltransferase 
                EC 2.4.1.84                       UDP-glucuronate—1,2-diacylglycerol glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.85                      cyanohydrin β-glucosyltransferase 
                EC 2.4.1.86                      N-acetyl-β-D-glucosaminide β-(1,3)-galactosyltransferase 
                EC 2.4.1.87                      N-acetyllactosaminide 3-α-galactosyltransferase 
                EC 2.4.1.88                      globoside α-N-acetylgalactosaminyltransferase 
                EC 2.4.1.89                      galactosylglucosaminylgalactosylglucosylceramide α-L-fucosyltransferase. Now included with EC 2.4.1.69, type 1 galactoside α-(1,2)-fucosyltransferase 
                EC 2.4.1.90                      N-acetyllactosamine synthase 
                EC 2.4.1.91                      flavonol 3-O-glucosyltransferase 
                EC 2.4.1.92                      (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase 
                EC 2.4.1.93                      inulin fructotransferase (depolymerizing, difructofuranose-1,2′:2,3′-dianhydride-forming). Now EC 4.2.2.18, inulin fructotransferase (DFA-III-forming). The enzyme was wrongly classified as a transferase rather than a lyase 
                EC 2.4.1.94                      protein N-acetylglucosaminyltransferase 
                EC 2.4.1.95                      bilirubin-glucuronoside glucuronosyltransferase 
                EC 2.4.1.96                      sn-glycerol-3-phosphate 1-galactosyltransferase 
                EC 2.4.1.97                      1,3-β-D-glucan phosphorylase 
                EC 2.4.1.98                       UDP-galactose—N-acetylglucosamine β-D-galactosyl-transferase. Now included with EC 2.4.1.90, N-acetyllactosamine synthase 
                EC 2.4.1.99                      sucrose:sucrose fructosyltransferase 
                EC 2.4.1.100                      2,1-fructan:2,1-fructan 1-fructosyltransferase 
                EC 2.4.1.101                      α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.102                      β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase 
                EC 2.4.1.103                      alizarin 2-β-glucosyltransferase 
                EC 2.4.1.104                      o-dihydroxycoumarin 7-O-glucosyltransferase 
                EC 2.4.1.105                      vitexin β-glucosyltransferase 
                EC 2.4.1.106                      isovitexin β-glucosyltransferase 
                EC 2.4.1.107                       UDP-glucuronate—testosterone glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.108                       UDP-glucuronate—phenol glucuronosyltransferase. Now included with EC 2.4.1.17, glucuronosyltransferase 
                EC 2.4.1.109                      dolichyl-phosphate-mannose—protein mannosyltransferase 
                EC 2.4.1.110                      tRNA-queuosine α-mannosyltransferase 
                EC 2.4.1.111                      coniferyl-alcohol glucosyltransferase 
                EC 2.4.1.112                      α-1,4-glucan-protein synthase (UDP-forming). The protein referred to in this entry is now known to be glycogenin so the entry has been incorporated into EC 2.4.1.186, glycogenin glucosyltransferase 
                EC 2.4.1.113                      α-1,4-glucan-protein synthase (ADP-forming) 
                EC 2.4.1.114                      2-coumarate O-β-glucosyltransferase 
                EC 2.4.1.115                      anthocyanidin 3-O-glucosyltransferase 
                EC 2.4.1.116                      cyanidin 3-O-rutinoside 5-O-glucosyltransferase 
                EC 2.4.1.117                      dolichyl-phosphate β-glucosyltransferase 
                EC 2.4.1.118                      cytokinin 7-β-glucosyltransferase 
                EC 2.4.1.119                      dolichyl-diphosphooligosaccharideprotein glycotransferase. As the enzyme transfers more than one hexosyl group, it has been transferred to EC 2.4.99.18, dolichyl-diphosphooligosaccharideprotein glycotransferase 
                EC 2.4.1.120                      sinapate 1-glucosyltransferase 
                EC 2.4.1.121                      indole-3-acetate β-glucosyltransferase 
                EC 2.4.1.122                      N-acetylgalactosaminide β-1,3-galactosyltransferase 
                EC 2.4.1.123                      inositol 3-α-galactosyltransferase 
                EC 2.4.1.124                      N-acetyllactosamine 3-α-galactosyltransferase. Now EC 2.4.1.87, N-acetyllactosaminide 3-α-galactosyltransferase 
                EC 2.4.1.125                      sucrose—1,6-α-glucan 3(6)-α-glucosyltransferase 
                EC 2.4.1.126                      hydroxycinnamate 4-β-glucosyltransferase 
                EC 2.4.1.127                      monoterpenol β-glucosyltransferase 
                EC 2.4.1.128                      scopoletin glucosyltransferase 
                EC 2.4.1.129                      peptidoglycan glycosyltransferase. Now EC 2.4.99.28, peptidoglycan glycosyltransferase 
                EC 2.4.1.130                      dolichyl-phosphate-mannose—glycolipid α-mannosyltransferase. Now covered by EC 2.4.1.258 (Dol-P-Man:Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase), EC 2.4.1.259 (Dol-P-Man:Man6GlcNAc2-PP-Dol α-1,2-mannosyltransferase), EC 2.4.1.260 (Dol-P-Man:Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase) and EC 2.4.1.261 (Dol-P-Man:Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase). 
                EC 2.4.1.131                      GDP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase 
                EC 2.4.1.132                      GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase 
                EC 2.4.1.133                      xylosylprotein 4-β-galactosyltransferase 
                EC 2.4.1.134                      galactosylxylosylprotein 3-β-galactosyltransferase 
                EC 2.4.1.135                      galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase 
                EC 2.4.1.136                      gallate 1-β-glucosyltransferase 
                EC 2.4.1.137                      sn-glycerol-3-phosphate 2-α-galactosyltransferase 
                EC 2.4.1.138                      mannotetraose 2-α-N-acetylglucosaminyltransferase 
                EC 2.4.1.139                      maltose synthase 
                EC 2.4.1.140                      alternansucrase 
                EC 2.4.1.141                      N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase 
                EC 2.4.1.142                      chitobiosyldiphosphodolichol β-mannosyltransferase 
                EC 2.4.1.143                      α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.144                      β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.145                      α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.146                      β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase 
                EC 2.4.1.147                      acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-acetylglucosaminyltransferase 
                EC 2.4.1.148                      acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,6-N-acetylglucosaminyltransferase 
                EC 2.4.1.149                      N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase 
                EC 2.4.1.150                      N-acetyllactosaminide β-1,6-N-acetylglucosaminyltransferase 
                EC 2.4.1.151                      N-acetyllactosaminide α-1,3-galactosyltransferase. Now EC 2.4.1.87, N-acetyllactosaminide 3-α-galactosyltransferase 
                EC 2.4.1.152                      4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase 
                EC 2.4.1.153                      UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminyltransferase 
                EC 2.4.1.154                      globotriosylceramide β-1,6-N-acetylgalactosaminyl-transferase. The enzyme is identical to EC 2.4.1.79, globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase. The reference cited referred to a 1→3 linkage and not to a 1→6 linkage, as indicated in the enzyme entry 
                EC 2.4.1.155                      α-1,6-mannosyl-glycoprotein 6-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.156                      indolylacetyl-myo-inositol galactosyltransferase 
                EC 2.4.1.157                      1,2-diacylglycerol 3-glucosyltransferase. Now classified as EC 2.4.1.336, monoglucosyldiacylglycerol synthase, and EC 2.4.1.337, 1,2-diacylglycerol 3-α-glucosyltransferase 
                EC 2.4.1.158                      13-hydroxydocosanoate 13-β-glucosyltransferase 
                EC 2.4.1.159                      flavonol-3-O-glucoside L-rhamnosyltransferase 
                EC 2.4.1.160                      pyridoxine 5′-O-β-D-glucosyltransferase 
                EC 2.4.1.161                      oligosaccharide 4-α-D-glucosyltransferase 
                EC 2.4.1.162                      aldose β-D-fructosyltransferase 
                EC 2.4.1.163                      β-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,3-acetylglucosaminyltransferase, now included in EC 2.4.1.149, N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase 
                EC 2.4.1.164                      galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-acetylglucosaminyltransferase, now included with EC 2.4.1.150, N-acetyllactosaminide β-1,6-N-acetylglucosaminyltransferase 
                EC 2.4.1.165                      N-acetylneuraminylgalactosylglucosylceramide β-1,4-N-acetylgalactosaminyltransferase 
                EC 2.4.1.166                      raffinose—raffinose α-galactosyltransferase 
                EC 2.4.1.167                      sucrose 6F-α-galactosyltransferase 
                EC 2.4.1.168                      xyloglucan 4-glucosyltransferase 
                EC 2.4.1.169                      xyloglucan 6-xylosyltransferase. Now EC 2.4.2.39, xyloglucan 6-xylosyltransferase 
                EC 2.4.1.170                      isoflavone 7-O-glucosyltransferase 
                EC 2.4.1.171                      methyl-ONN-azoxymethanol β-D-glucosyltransferase 
                EC 2.4.1.172                      salicyl-alcohol β-D-glucosyltransferase 
                EC 2.4.1.173                      sterol 3β-glucosyltransferase 
                EC 2.4.1.174                      glucuronylgalactosylproteoglycan 4-β-N-acetylgalactosaminyltransferase 
                EC 2.4.1.175                      glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-β-N-acetylgalactosaminyltransferase 
                EC 2.4.1.176                      gibberellin β-D-glucosyltransferase 
                EC 2.4.1.177                      cinnamate β-D-glucosyltransferase 
                EC 2.4.1.178                      hydroxymandelonitrile glucosyltransferase 
                EC 2.4.1.179                      lactosylceramide β-1,3-galactosyltransferase 
                EC 2.4.1.180                      lipopolysaccharide N-acetylmannosaminouronosyltransferase 
                EC 2.4.1.181                      hydroxyanthraquinone glucosyltransferase 
                EC 2.4.1.182                      lipid-A-disaccharide synthase 
                EC 2.4.1.183                      α-1,3-glucan synthase 
                EC 2.4.1.184                      galactolipid galactosyltransferase 
                EC 2.4.1.185                      flavanone 7-O-β-glucosyltransferase 
                EC 2.4.1.186                      glycogenin glucosyltransferase 
                EC 2.4.1.187                      N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-β-D-mannosaminyltransferase 
                EC 2.4.1.188                      N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase 
                EC 2.4.1.189                      luteolin 7-O-glucuronosyltransferase 
                EC 2.4.1.190                      luteolin-7-O-glucuronide 2′′-O-glucuronosyltransferase 
                EC 2.4.1.191                      luteolin-7-O-diglucuronide 4′-O-glucuronosyltransferase 
                EC 2.4.1.192                      nuatigenin 3β-glucosyltransferase 
                EC 2.4.1.193                      sarsapogenin 3β-glucosyltransferase 
                EC 2.4.1.194                      4-hydroxybenzoate 4-O-β-D-glucosyltransferase 
                EC 2.4.1.195                      N-hydroxythioamide S-β-glucosyltransferase 
                EC 2.4.1.196                      nicotinate glucosyltransferase 
                EC 2.4.1.197                      high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase 
                EC 2.4.1.198                      phosphatidylinositol N-acetylglucosaminyltransferase 
                EC 2.4.1.199                      β-mannosylphosphodecaprenol—mannooligosaccharide 6-mannosyltransferase 
                EC 2.4.1.200                      inulin fructotransferase (depolymerizing, difructofuranose-1,2′:2′,1-dianhydride-forming). Now EC 4.2.2.17, inulin fructotransferase (DFA-I-forming). The enzyme was wrongly classified as a transferase rather than a lyase 
                EC 2.4.1.201                      α-1,6-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.202                      2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase 
                EC 2.4.1.203                      trans-zeatin O-β-D-glucosyltransferase 
                EC 2.4.1.204                      zeatin O-β-D-xylosyltransferase. Now EC 2.4.2.40, zeatin O-β-D-xylosyltransferase 
                EC 2.4.1.205                      galactogen 6β-galactosyltransferase 
                EC 2.4.1.206                      lactosylceramide 1,3-N-acetyl-β-D-glucosaminyltransferase 
                EC 2.4.1.207                      xyloglucan:xyloglucosyl transferase 
                EC 2.4.1.208                      diglucosyl diacylglycerol synthase (1,2-linking) 
                EC 2.4.1.209                      cis-p-coumarate glucosyltransferase 
                EC 2.4.1.210                      limonoid glucosyltransferase 
                EC 2.4.1.211                      1,3-β-galactosyl-N-acetylhexosamine phosphorylase 
                EC 2.4.1.212                      hyaluronan synthase 
                EC 2.4.1.213                      glucosylglycerol-phosphate synthase 
                EC 2.4.1.214                      glycoprotein 3-α-L-fucosyltransferase 
                EC 2.4.1.215                      cis-zeatin O-β-D-glucosyltransferase 
                EC 2.4.1.216                      trehalose 6-phosphate phosphorylase 
                EC 2.4.1.217                      mannosyl-3-phosphoglycerate synthase 
                EC 2.4.1.218                      hydroquinone glucosyltransferase 
                EC 2.4.1.219                      vomilenine glucosyltransferase 
                EC 2.4.1.220                      indoxyl-UDPG glucosyltransferase 
                EC 2.4.1.221                      peptide-O-fucosyltransferase 
                EC 2.4.1.222                      O-fucosylpeptide 3-β-N-acetylglucosaminyltransferase 
                EC 2.4.1.223                      glucuronosyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase 
                EC 2.4.1.224                      glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-α-N-acetylglucosaminyltransferase 
                EC 2.4.1.225                      N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase 
                EC 2.4.1.226                      N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase 
                EC 2.4.1.227                      undecaprenyldiphospho-muramoylpentapeptide β-N-acetylglucosaminyltransferase 
                EC 2.4.1.228                      lactosylceramide 4-α-galactosyltransferase 
                EC 2.4.1.229                      [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase 
                EC 2.4.1.230                      kojibiose phosphorylase 
                EC 2.4.1.231                      α,α-trehalose phosphorylase (configuration-retaining) 
                EC 2.4.1.232                      initiation-specific α-1,6-mannosyltransferase 
                EC 2.4.1.233                       anthocyanidin 3-O-glucosyltransferase. The enzyme is identical to EC 2.4.1.115, anthocyanidin 3-O-glucosyltransferase 
                EC 2.4.1.234                      kaempferol 3-O-galactosyltransferase 
                EC 2.4.1.235                      cyanidin 3-O-rutinoside 5-O-glucosyltransferase. Enzyme is identical to EC 2.4.1.116, cyanidin 3-O-rutinoside 5-O-glucosyltransferase 
                EC 2.4.1.236                      flavanone 7-O-glucoside 2′′-O-β-L-rhamnosyltransferase 
                EC 2.4.1.237                      flavonol 7-O-β-glucosyltransferase 
                EC 2.4.1.238                      delphinidin 3,5-di-O-glucoside 3′-O-glucosyltransferase 
                EC 2.4.1.239                      flavonol-3-O-glucoside glucosyltransferase 
                EC 2.4.1.240                      flavonol-3-O-glycoside glucosyltransferase 
                EC 2.4.1.241                      digalactosyldiacylglycerol synthase 
                EC 2.4.1.242                      NDP-glucose—starch glucosyltransferase 
                EC 2.4.1.243                      6G-fructosyltransferase 
                EC 2.4.1.244                      N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-acetylgalactosaminyltransferase 
                EC 2.4.1.245                      α,α-trehalose synthase 
                EC 2.4.1.246                      mannosylfructose-phosphate synthase 
                EC 2.4.1.247                      β-D-galactosyl-(1→4)-L-rhamnose phosphorylase 
                EC 2.4.1.248                      cycloisomaltooligosaccharide glucanotransferase 
                EC 2.4.1.249                      delphinidin 3′,5′-O-glucosyltransferase 
                EC 2.4.1.250                      D-inositol-3-phosphate glycosyltransferase 
                EC 2.4.1.251                      GlcA-β-(1→2)-D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol 4-β-mannosyltransferase 
                EC 2.4.1.252                      GDP-mannose:cellobiosyl-diphosphopolyprenol α-mannosyltransferase 
                EC 2.4.1.253                      baicalein 7-O-glucuronosyltransferase 
                EC 2.4.1.254                      cyanidin-3-O-glucoside 2′′-O-glucuronosyltransferase 
                EC 2.4.1.255                      protein O-GlcNAc transferase 
                EC 2.4.1.256                      dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol α-1,2-glucosyltransferase 
                EC 2.4.1.257                      GDP-Man:Man2GlcNAc2-PP-dolichol α-1,6-mannosyltransferase 
                EC 2.4.1.258                      dolichyl-P-Man:Man5GlcNAc2-PP-dolichol α-1,3-mannosyltransferase 
                EC 2.4.1.259                      dolichyl-P-Man:Man6GlcNAc2-PP-dolichol α-1,2-mannosyltransferase 
                EC 2.4.1.260                      dolichyl-P-Man:Man7GlcNAc2-PP-dolichol α-1,6-mannosyltransferase 
                EC 2.4.1.261                      dolichyl-P-Man:Man8GlcNAc2-PP-dolichol α-1,2-mannosyltransferase 
                EC 2.4.1.262                      soyasapogenol glucuronosyltransferase 
                EC 2.4.1.263                      abscisate β-glucosyltransferase 
                EC 2.4.1.264                      D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphosphoundecaprenol 2-β-glucuronosyltransferase 
                EC 2.4.1.265                      dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol α-1,3-glucosyltransferase 
                EC 2.4.1.266                      glucosyl-3-phosphoglycerate synthase 
                EC 2.4.1.267                      dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol α-1,3-glucosyltransferase 
                EC 2.4.1.268                      glucosylglycerate synthase 
                EC 2.4.1.269                      mannosylglycerate synthase 
                EC 2.4.1.270                      mannosylglucosyl-3-phosphoglycerate synthase 
                EC 2.4.1.271                      crocetin glucosyltransferase 
                EC 2.4.1.272                      soyasapogenol B glucuronide galactosyltransferase 
                EC 2.4.1.273                      soyasaponin III rhamnosyltransferase 
                EC 2.4.1.274                      glucosylceramide β-1,4-galactosyltransferase 
                EC 2.4.1.275                      neolactotriaosylceramide β-1,4-galactosyltransferase 
                EC 2.4.1.276                      zeaxanthin glucosyltransferase 
                EC 2.4.1.277                      10-deoxymethynolide desosaminyltransferase 
                EC 2.4.1.278                      3-α-mycarosylerythronolide B desosaminyl transferase 
                EC 2.4.1.279                      nigerose phosphorylase 
                EC 2.4.1.280                      N,N′-diacetylchitobiose phosphorylase 
                EC 2.4.1.281                      4-O-β-D-mannosyl-D-glucose phosphorylase 
                EC 2.4.1.282                      3-O-α-D-glucosyl-L-rhamnose phosphorylase 
                EC 2.4.1.283                      2-deoxystreptamine N-acetyl-D-glucosaminyltransferase 
                EC 2.4.1.284                      2-deoxystreptamine glucosyltransferase 
                EC 2.4.1.285                      UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase 
                EC 2.4.1.286                      chalcone 4′-O-glucosyltransferase 
                EC 2.4.1.287                      rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol β-1,4/1,5-galactofuranosyltransferase 
                EC 2.4.1.288                      galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol β-1,5/1,6-galactofuranosyltransferase 
                EC 2.4.1.289                      N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase 
                EC 2.4.1.290                      N,N′-diacetylbacillosaminyl-diphospho-undecaprenol α-1,3-N-acetylgalactosaminyltransferase 
                EC 2.4.1.291                      N-acetylgalactosamine-N,N′-diacetylbacillosaminyl-diphospho-undecaprenol 4-α-N-acetylgalactosaminyltransferase 
                EC 2.4.1.292                      GalNAc-α-(1→4)-GalNAc-α-(1→3)-diNAcBac-PP-undecaprenol α-1,4-N-acetyl-D-galactosaminyltransferase 
                EC 2.4.1.293                      GalNAc5-diNAcBac-PP-undecaprenol β-1,3-glucosyltransferase 
                EC 2.4.1.294                      cyanidin 3-O-galactosyltransferase 
                EC 2.4.1.295                      anthocyanin 3-O-sambubioside 5-O-glucosyltransferase 
                EC 2.4.1.296                      anthocyanidin 3-O-coumaroylrutinoside 5-O-glucosyltransferase 
                EC 2.4.1.297                      anthocyanidin 3-O-glucoside 2′′-O-glucosyltransferase 
                EC 2.4.1.298                      anthocyanidin 3-O-glucoside 5-O-glucosyltransferase 
                EC 2.4.1.299                      cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose) 
                EC 2.4.1.300                      cyanidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose) 
                EC 2.4.1.301                      2′-deamino-2′-hydroxyneamine 1-α-D-kanosaminyltransferase 
                EC 2.4.1.302                      L-demethylnoviosyl transferase 
                EC 2.4.1.303                      UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol β-1,3-galactosyltransferase 
                EC 2.4.1.304                      UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol β-1,4-galactosyltransferase 
                EC 2.4.1.305                      UDP-Glc:α-D-GlcNAc-glucosaminyl-diphosphoundecaprenol β-1,3-glucosyltransferase 
                EC 2.4.1.306                      UDP-GalNAc:α-D-GalNAc-diphosphoundecaprenol α-1,3-N-acetylgalactosaminyltransferase  
                EC 2.4.1.307                      UDP-Gal:α-D-GalNAc-1,3-α-D-GalNAc-diphosphoundecaprenol β-1,3-galactosyltransferase. Now included in EC 2.4.1.122, glycoprotein-N-acetylgalactosamine β-1,3-galactosyltransferase 
                EC 2.4.1.308                      GDP-Fuc:β-D-Gal-1,3-α-D-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,2-fucosyltransferase 
                EC 2.4.1.309                      UDP-Gal:α-L-Fuc-1,2-β-Gal-1,3-α-GalNAc-1,3-α-GalNAc-diphosphoundecaprenol α-1,3-galactosyltransferase 
                EC 2.4.1.310                      vancomycin aglycone glucosyltransferase 
                EC 2.4.1.311                      chloroorienticin B synthase 
                EC 2.4.1.312                      protein O-mannose β-1,4-N-acetylglucosaminyltransferase 
                EC 2.4.1.313                      protein O-mannose β-1,3-N-acetylgalactosaminyltransferase 
                EC 2.4.1.314                      ginsenoside Rd glucosyltransferase 
                EC 2.4.1.315                      diglucosyl diacylglycerol synthase (1,6-linking) 
                EC 2.4.1.316                      tylactone mycaminosyltransferase 
                EC 2.4.1.317                      O-mycaminosyltylonolide 6-deoxyallosyltransferase 
                EC 2.4.1.318                      demethyllactenocin mycarosyltransferase 
                EC 2.4.1.319                      β-1,4-mannooligosaccharide phosphorylase 
                EC 2.4.1.320                      1,4-β-mannosyl-N-acetylglucosamine phosphorylase 
                EC 2.4.1.321                      cellobionic acid phosphorylase 
                EC 2.4.1.322                      devancosaminyl-vancomycin vancosaminetransferase 
                EC 2.4.1.323                      7-deoxyloganetic acid glucosyltransferase 
                EC 2.4.1.324                      7-deoxyloganetin glucosyltransferase 
                EC 2.4.1.325                      TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase 
                EC 2.4.1.326                      aklavinone 7-L-rhodosaminyltransferase 
                EC 2.4.1.327                      aclacinomycin-T 2-deoxy-L-fucose transferase 
                EC 2.4.1.328                      erythronolide mycarosyltransferase 
                EC 2.4.1.329                      sucrose 6F-phosphate phosphorylase 
                EC 2.4.1.330                      β-D-glucosyl crocetin β-1,6-glucosyltransferase 
                EC 2.4.1.331                      8-demethyltetracenomycin C L-rhamnosyltransferase 
                EC 2.4.1.332                      1,2-α-glucosylglycerol phosphorylase 
                EC 2.4.1.333                      1,2-β-oligoglucan phosphorylase 
                EC 2.4.1.334                      1,3-α-oligoglucan phosphorylase 
                EC 2.4.1.335                      dolichyl N-acetyl-α-D-glucosaminyl phosphate 3-β-D-2,3-diacetamido-2,3-dideoxy-β-D-glucuronosyltransferase 
                EC 2.4.1.336                      monoglucosyldiacylglycerol synthase 
                EC 2.4.1.337                      1,2-diacylglycerol 3-α-glucosyltransferase 
                EC 2.4.1.338                      validoxylamine A glucosyltransferase 
                EC 2.4.1.339                      β-1,2-mannobiose phosphorylase 
                EC 2.4.1.340                      1,2-β-oligomannan phosphorylase 
                EC 2.4.1.341                      α-1,2-colitosyltransferase 
                EC 2.4.1.342                      α-maltose-1-phosphate synthase 
                EC 2.4.1.343                      UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol α-1,3-galactosyltransferase 
                EC 2.4.1.344                      type 2 galactoside α-(1,2)-fucosyltransferase 
                EC 2.4.1.345                      phosphatidyl-myo-inositol α-mannosyltransferase 
                EC 2.4.1.346                      phosphatidyl-myo-inositol dimannoside synthase 
                EC 2.4.1.347                      α,α-trehalose-phosphate synthase (ADP-forming) 
                EC 2.4.1.348                      N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-α-mannosyltransferase 
                EC 2.4.1.349                      mannosyl-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-α-mannosyltransferase 
                EC 2.4.1.350                      mogroside IE synthase 
                EC 2.4.1.351                      rhamnogalacturonan I rhamnosyltransferase 
                EC 2.4.1.352                      glucosylglycerate phosphorylase 
                EC 2.4.1.353                      sordaricin 6-deoxyaltrosyltransferase 
                EC 2.4.1.354                      (R)-mandelonitrile β-glucosyltransferase 
                EC 2.4.1.355                      poly(ribitol-phosphate) β-N-acetylglucosaminyltransferase 
                EC 2.4.1.356                      glucosyl-dolichyl phosphate glucuronosyltransferase 
                EC 2.4.1.357                      phlorizin synthase 
                EC 2.4.1.358                      acylphloroglucinol glucosyltransferase 
                EC 2.4.1.359                      glucosylglycerol phosphorylase (configuration-retaining) 
                EC 2.4.1.360                      2-hydroxyflavanone C-glucosyltransferase 
                EC 2.4.1.361                      GDP-mannose:di-myo-inositol-1,3′-phosphate β-1,2-mannosyltransferase 
                EC 2.4.1.362                      α-(1→3) branching sucrase 
                EC 2.4.1.363                      ginsenoside 20-O-glucosyltransferase 
                EC 2.4.1.364                      protopanaxadiol-type ginsenoside 3-O-glucosyltransferase 
                EC 2.4.1.365                      protopanaxadiol-type ginsenoside-3-O-glucoside 2′′-O-glucosyltransferase 
                EC 2.4.1.366                      ginsenoside F1 6-O-glucosyltransferase 
                EC 2.4.1.367                      ginsenoside 6-O-glucosyltransferase 
                EC 2.4.1.368                      oleanolate 3-O-glucosyltransferase 
                EC 2.4.1.369                      enterobactin C-glucosyltransferase 
                EC 2.4.1.370                      inositol phosphorylceramide mannosyltransferase 
                EC 2.4.1.371                      polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 2,3-α-mannosylpolymerase 
                EC 2.4.1.372                      mutansucrase 
                EC 2.4.1.373                      α-(1→2) branching sucrase 
                EC 2.4.1.374                      β-1,2-mannooligosaccharide synthase 
                EC 2.4.1.375                      rhamnogalacturonan I galactosyltransferase 
                EC 2.4.1.376                      EGF-domain serine glucosyltransferase 
                EC 2.4.1.377                      dTDP-Rha:α-D-Gal-diphosphoundecaprenol α-1,3-rhamnosyltransferase 
                EC 2.4.1.378                      GDP-mannose:α-L-Rha-(1→3)-α-D-Gal-PP-Und α-1,4-mannosyltransferase 
                EC 2.4.1.379                      GDP-Man:α-D-Gal-diphosphoundecaprenol α-1,3-mannosyltransferase 
                EC 2.4.1.380                      GDP-Man:α-D-Man-(1→3)-α-D-Gal diphosphoundecaprenol α-1,2-mannosyltransferase 
                EC 2.4.1.381                      dTDP-Rha:α-D-Man-(1→3)-α-D-Gal diphosphoundecaprenol α-1,2-rhamnosyltransferase 
                EC 2.4.1.382                      CDP-abequose:α-L-Rha2OAc-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-α-D-Gal-PP-Und α-1,3-abequosyltransferase 
                EC 2.4.1.383                      GDP-Man:α-L-Rha-(1→3)-α-D-Gal-PP-Und β-1,4-mannosyltransferase 
                EC 2.4.1.384                      NDP-glycosyltransferase 
                EC 2.4.1.385                      sterol 27-β-glucosyltransferase 
                EC 2.4.1.386                      GlcNAc-β-1,3-Gal β-1,6-N-acetylglucosaminyltransferase (distally acting) 
                EC 2.4.1.387                      isomaltosyltransferase 
                EC 2.4.1.388                      glucosylgalactose phosphorylase 
                EC 2.4.1.389                      solabiose phosphorylase 
                EC 2.4.1.390                      4,3-α-glucanotransferase 
                EC 2.4.1.391                      β-1,2-glucosyltransferase 
                EC 2.4.1.392                      3-O-β-D-glucopyranosyl-β-D-glucuronide phosphorylase 
                EC 2.4.1.393                      MMP α-(1→4)-mannosyltransferase 
                EC 2.4.1.394                      4,6-α-glucanotransferase (linear substrates/linear products) 
                EC 2.4.1.395                      reuteransucrase 
                EC 2.4.1.396                      4,6-α-glucanotransferase (linear and branched substrates, branched products) 
        EC 2.4.2       []    Pentosyltransferases 
                EC 2.4.2.1                      purine-nucleoside phosphorylase 
                EC 2.4.2.2                      pyrimidine-nucleoside phosphorylase 
                EC 2.4.2.3                      uridine phosphorylase 
                EC 2.4.2.4                      thymidine phosphorylase 
                EC 2.4.2.5                      nucleoside ribosyltransferase 
                EC 2.4.2.6                      nucleoside deoxyribosyltransferase 
                EC 2.4.2.7                      adenine phosphoribosyltransferase 
                EC 2.4.2.8                      hypoxanthine phosphoribosyltransferase 
                EC 2.4.2.9                      uracil phosphoribosyltransferase 
                EC 2.4.2.10                      orotate phosphoribosyltransferase 
                EC 2.4.2.11                      nicotinate phosphoribosyltransferase. Now EC 6.3.4.21, nicotinate phosphoribosyltransferase. 
                EC 2.4.2.12                      nicotinamide phosphoribosyltransferase 
                EC 2.4.2.13                      now EC 2.5.1.6 methionine adenosyltransferase 
                EC 2.4.2.14                      amidophosphoribosyltransferase 
                EC 2.4.2.15                      guanosine phosphorylase 
                EC 2.4.2.16                      urate-ribonucleoside phosphorylase 
                EC 2.4.2.17                      ATP phosphoribosyltransferase 
                EC 2.4.2.18                      anthranilate phosphoribosyltransferase 
                EC 2.4.2.19                      nicotinate-nucleotide diphosphorylase (carboxylating) 
                EC 2.4.2.20                      dioxotetrahydropyrimidine phosphoribosyltransferase 
                EC 2.4.2.21                      nicotinate-nucleotide—dimethylbenzimidazole phosphoribosyltransferase 
                EC 2.4.2.22                      xanthine phosphoribosyltransferase 
                EC 2.4.2.23                      deoxyuridine phosphorylase. This activity has been shown to be catalysed by EC 2.4.2.2, pyrimidine-nucleoside phosphorylase, EC 2.4.2.3, uridine phosphorylase, and EC 2.4.2.4, thymidine phosphorylase. 
                EC 2.4.2.24                      1,4-β-D-xylan synthase 
                EC 2.4.2.25                      flavone apiosyltransferase 
                EC 2.4.2.26                      protein xylosyltransferase 
                EC 2.4.2.27                      dTDP-dihydrostreptose—streptidine-6-phosphate dihydrostreptosyltransferase 
                EC 2.4.2.28                      S-methyl-5′-thioadenosine phosphorylase 
                EC 2.4.2.29                      tRNA-guanosine34 preQ1 transglycosylase 
                EC 2.4.2.30                      NAD+ ADP-ribosyltransferase 
                EC 2.4.2.31                      NAD+—protein-arginine ADP-ribosyltransferase 
                EC 2.4.2.32                      dolichyl-phosphate D-xylosyltransferase 
                EC 2.4.2.33                      dolichyl-xylosyl-phosphate—protein xylosyltransferase 
                EC 2.4.2.34                      indolylacetylinositol arabinosyltransferase 
                EC 2.4.2.35                      flavonol-3-O-glycoside xylosyltransferase 
                EC 2.4.2.36                      NAD+—diphthamide ADP-ribosyltransferase 
                EC 2.4.2.37                      NAD+—dinitrogen-reductase ADP-D-ribosyltransferase 
                EC 2.4.2.38                      glycoprotein 2-β-D-xylosyltransferase 
                EC 2.4.2.39                      xyloglucan 6-xylosyltransferase 
                EC 2.4.2.40                      zeatin O-β-D-xylosyltransferase 
                EC 2.4.2.41                      xylogalacturonan β-1,3-xylosyltransferase 
                EC 2.4.2.42                      UDP-D-xylose:β-D-glucoside α-1,3-D-xylosyltransferase 
                EC 2.4.2.43                      lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase 
                EC 2.4.2.44                      S-methyl-5′-thioinosine phosphorylase 
                EC 2.4.2.45                      decaprenyl-phosphate phosphoribosyltransferase 
                EC 2.4.2.46                      galactan 5-O-arabinofuranosyltransferase 
                EC 2.4.2.47                      arabinofuranan 3-O-arabinosyltransferase 
                EC 2.4.2.48                      tRNA-guanine15 transglycosylase 
                EC 2.4.2.49                      neamine phosphoribosyltransferase 
                EC 2.4.2.50                      cyanidin 3-O-galactoside 2′′-O-xylosyltransferase 
                EC 2.4.2.51                      anthocyanidin 3-O-glucoside 2′′′-O-xylosyltransferase 
                EC 2.4.2.52                      triphosphoribosyl-dephospho-CoA synthase 
                EC 2.4.2.53                      undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase 
                EC 2.4.2.54                      β-ribofuranosylphenol 5′-phosphate synthase 
                EC 2.4.2.55                      nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase 
                EC 2.4.2.56                      kaempferol 3-O-xylosyltransferase 
                EC 2.4.2.57                      AMP phosphorylase 
                EC 2.4.2.58                      hydroxyproline O-arabinosyltransferase 
                EC 2.4.2.59                      sulfide-dependent adenosine diphosphate thiazole synthase 
                EC 2.4.2.60                      cysteine-dependent adenosine diphosphate thiazole synthase 
                EC 2.4.2.61                      α-dystroglycan β1,4-xylosyltransferase 
                EC 2.4.2.62                      xylosyl α-1,3-xylosyltransferase 
                EC 2.4.2.63                      EGF-domain serine xylosyltransferase 
                EC 2.4.2.64                      tRNA-guanosine34 queuine transglycosylase 
        EC 2.4.3       []    Sialyltransferases 
                EC 2.4.3.1                      β-galactoside α-(2,6)-sialyltransferase 
                EC 2.4.3.2                      β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminide α-2,3-sialyltransferase 
                EC 2.4.3.3                      α-N-acetylgalactosaminide α-2,6-sialyltransferase 
                EC 2.4.3.4                      β-galactoside α-2,3-sialyltransferase 
                EC 2.4.3.5                      galactosyldiacylglycerol α-2,3-sialyltransferase 
                EC 2.4.3.6                      N-acetyllactosaminide α-2,3-sialyltransferase 
                EC 2.4.3.7                      α-N-acetylneuraminyl-2,3-β-galactosyl-1,3-N-acetylgalactosaminide 6-α-sialyltransferase 
                EC 2.4.3.8                      α-N-acetylneuraminate α-2,8-sialyltransferase 
                EC 2.4.3.9                      lactosylceramide α-2,3-sialyltransferase 
                EC 2.4.3.10                      N-acetylglucosaminide α-(2,6)-sialyltransferase 
        EC 2.4.99       []    Transferring other glycosyl groups 
                EC 2.4.99.1                      β-galactoside α-(2,6)-sialyltransferase. Now EC 2.4.3.1, β-galactoside α-(2,6)-sialyltransferase 
                EC 2.4.99.2                      β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminide α-2,3-sialyltransferase. Now EC 2.4.3.2, β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminide α-2,3-sialyltransferase 
                EC 2.4.99.3                      α-N-acetylgalactosaminide α-2,6-sialyltransferase. Now EC 2.4.3.3, α-N-acetylgalactosaminide α-2,6-sialyltransferase 
                EC 2.4.99.4                      β-galactoside α-2,3-sialyltransferase. Now EC 2.4.3.4, β-galactoside α-2,3-sialyltransferase 
                EC 2.4.99.5                      galactosyldiacylglycerol α-2,3-sialyltransferase. Now EC 2.4.3.5, galactosyldiacylglycerol α-2,3-sialyltransferase 
                EC 2.4.99.6                      N-acetyllactosaminide α-2,3-sialyltransferase. Now EC 2.4.3.6, N-acetyllactosaminide α-2,3-sialyltransferase 
                EC 2.4.99.7                      α-N-acetylneuraminyl-2,3-β-galactosyl-1,3-N-acetylgalactosaminide 6-α-sialyltransferase. Now EC 2.4.3.7, α-N-acetylneuraminyl-2,3-β-galactosyl-1,3-N-acetylgalactosaminide 6-α-sialyltransferase 
                EC 2.4.99.8                      α-N-acetylneuraminate α-2,8-sialyltransferase. Now EC 2.4.3.8, α-N-acetylneuraminate α-2,8-sialyltransferase 
                EC 2.4.99.9                      lactosylceramide α-2,3-sialyltransferase. Now EC 2.4.3.9, lactosylceramide α-2,3-sialyltransferase 
                EC 2.4.99.10                      neolactotetraosylceramide α-2,3-sialyltransferase. Now included in EC 2.4.3.6, N-acetyllactosaminide α-2,3-sialyltransferase 
                EC 2.4.99.11                      lactosylceramide α-2,6-N-sialyltransferase. Now included with EC 2.4.3.1, β-galactoside α-(2,6)-sialyltransferase 
                EC 2.4.99.12                      lipid IVA 3-deoxy-D-manno-octulosonic acid transferase 
                EC 2.4.99.13                      (Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase 
                EC 2.4.99.14                      (Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase 
                EC 2.4.99.15                      (Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase 
                EC 2.4.99.16                      starch synthase (maltosyl-transferring) 
                EC 2.4.99.17                      S-adenosylmethionine:tRNA ribosyltransferase-isomerase 
                EC 2.4.99.18                      dolichyl-diphosphooligosaccharide—protein glycotransferase 
                EC 2.4.99.19                      undecaprenyl-diphosphooligosaccharide—protein glycotransferase 
                EC 2.4.99.20                      2′-phospho-ADP-ribosyl cyclase/2′-phospho-cyclic-ADP-ribose transferase 
                EC 2.4.99.21                      dolichyl-phosphooligosaccharide-protein glycotransferase 
                EC 2.4.99.22                      N-acetylglucosaminide α-(2,6)-sialyltransferase. Now EC 2.4.3.10, N-acetylglucosaminide α-(2,6)-sialyltransferase 
                EC 2.4.99.23                      lipopolysaccharide heptosyltransferase I 
                EC 2.4.99.24                      lipopolysaccharide heptosyltransferase II 
                EC 2.4.99.25                      lipopolysaccharide heptosyltransferase III 
                EC 2.4.99.26                      O-antigen ligase 
                EC 2.4.99.27                      O-antigen polymerase Wzy 
                EC 2.4.99.28                      peptidoglycan glycosyltransferase 
    EC 2.5  [+]      
        EC 2.5.1       []    Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) 
                EC 2.5.1.1                      dimethylallyltranstransferase 
                EC 2.5.1.2                      thiamine pyridinylase 
                EC 2.5.1.3                      thiamine phosphate synthase 
                EC 2.5.1.4                      adenosylmethionine cyclotransferase. Now classified as EC 4.4.1.42, S-adenosyl-L-methionine lyase 
                EC 2.5.1.5                      galactose-6-sulfurylase 
                EC 2.5.1.6                      methionine adenosyltransferase 
                EC 2.5.1.7                      UDP-N-acetylglucosamine 1-carboxyvinyltransferase 
                EC 2.5.1.8                      tRNA isopentenyltransferase. As it is now known that the substrate is dimethylallyl diphosphate, the enzyme has been transferred to EC 2.5.1.75, tRNA dimethylallyltransferase 
                EC 2.5.1.9                      riboflavin synthase 
                EC 2.5.1.10                      (2E,6E)-farnesyl diphosphate synthase 
                EC 2.5.1.11                      trans-octaprenyltranstransferase. Now covered by EC 2.5.1.84 (all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific]) and EC 2.5.1.85 (all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]) 
                EC 2.5.1.12                       glutathione S-alkyltransferase. Now included with EC 2.5.1.18 glutathione transferase 
                EC 2.5.1.13                       glutathione S-aryltransferase. Now included with EC 2.5.1.18 glutathione transferase 
                EC 2.5.1.14                       glutathione S-aralkyltransferase. Now included with EC 2.5.1.18 glutathione transferase 
                EC 2.5.1.15                      dihydropteroate synthase 
                EC 2.5.1.16                      spermidine synthase 
                EC 2.5.1.17                      corrinoid adenosyltransferase 
                EC 2.5.1.18                      glutathione transferase 
                EC 2.5.1.19                      3-phosphoshikimate 1-carboxyvinyltransferase 
                EC 2.5.1.20                      rubber cis-polyprenylcistransferase 
                EC 2.5.1.21                      squalene synthase 
                EC 2.5.1.22                      spermine synthase 
                EC 2.5.1.23                      sym-norspermidine synthase 
                EC 2.5.1.24                      discadenine synthase 
                EC 2.5.1.25                      tRNA-uridine aminocarboxypropyltransferase 
                EC 2.5.1.26                      alkylglycerone-phosphate synthase 
                EC 2.5.1.27                      adenylate dimethylallyltransferase (AMP-dependent) 
                EC 2.5.1.28                      dimethylallylcistransferase 
                EC 2.5.1.29                      geranylgeranyl diphosphate synthase 
                EC 2.5.1.30                      heptaprenyl diphosphate synthase 
                EC 2.5.1.31                      ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] 
                EC 2.5.1.32                      15-cis-phytoene synthase 
                EC 2.5.1.33                      trans-pentaprenyltranstransferase. Now covered by EC 2.5.1.82 (hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]) and EC 2.5.1.83 (hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]) 
                EC 2.5.1.34                      4-dimethylallyltryptophan synthase 
                EC 2.5.1.35                      aspulvinone dimethylallyltransferase 
                EC 2.5.1.36                      trihydroxypterocarpan dimethylallyltransferase 
                EC 2.5.1.37                      leukotriene-C4 synthase. Now EC 4.4.1.20, leukotriene-C4 synthase. The enzyme was incorrectly classified as a transferase 
                EC 2.5.1.38                      isonocardicin synthase 
                EC 2.5.1.39                      4-hydroxybenzoate polyprenyltransferase 
                EC 2.5.1.40                      aristolochene synthase. Now EC 4.2.3.9, aristolochene synthase 
                EC 2.5.1.41                      phosphoglycerol geranylgeranyltransferase 
                EC 2.5.1.42                      geranylgeranylglycerol-phosphate geranylgeranyltransferase 
                EC 2.5.1.43                      nicotianamine synthase 
                EC 2.5.1.44                      homospermidine synthase 
                EC 2.5.1.45                      homospermidine synthase (spermidine-specific) 
                EC 2.5.1.46                      deoxyhypusine synthase 
                EC 2.5.1.47                      cysteine synthase 
                EC 2.5.1.48                      cystathionine γ-synthase 
                EC 2.5.1.49                      O-acetylhomoserine aminocarboxypropyltransferase 
                EC 2.5.1.50                      zeatin 9-aminocarboxyethyltransferase 
                EC 2.5.1.51                      β-pyrazolylalanine synthase 
                EC 2.5.1.52                      L-mimosine synthase 
                EC 2.5.1.53                      uracilylalanine synthase 
                EC 2.5.1.54                      3-deoxy-7-phosphoheptulonate synthase 
                EC 2.5.1.55                      3-deoxy-8-phosphooctulonate synthase 
                EC 2.5.1.56                      N-acetylneuraminate synthase 
                EC 2.5.1.57                      N-acylneuraminate-9-phosphate synthase 
                EC 2.5.1.58                      protein farnesyltransferase 
                EC 2.5.1.59                      protein geranylgeranyltransferase type I 
                EC 2.5.1.60                      protein geranylgeranyltransferase type II 
                EC 2.5.1.61                      hydroxymethylbilane synthase 
                EC 2.5.1.62                      chlorophyll synthase 
                EC 2.5.1.63                      adenosyl-fluoride synthase 
                EC 2.5.1.64                      2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. The reaction that was attributed to this enzyme is now known to be catalysed by two separate enzymes: EC 2.2.1.9 (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase) and EC 4.2.99.20 (2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase) 
                EC 2.5.1.65                      O-phosphoserine sulfhydrylase 
                EC 2.5.1.66                      N2-(2-carboxyethyl)arginine synthase 
                EC 2.5.1.67                      chrysanthemyl diphosphate synthase 
                EC 2.5.1.68                      (2Z,6E)-farnesyl diphosphate synthase 
                EC 2.5.1.69                      lavandulyl diphosphate synthase 
                EC 2.5.1.70                      naringenin 8-dimethylallyltransferase 
                EC 2.5.1.71                      leachianone-G 2′′-dimethylallyltransferase 
                EC 2.5.1.72                      quinolinate synthase 
                EC 2.5.1.73                      O-phospho-L-seryl-tRNA:Cys-tRNA synthase 
                EC 2.5.1.74                      1,4-dihydroxy-2-naphthoate polyprenyltransferase 
                EC 2.5.1.75                      tRNA dimethylallyltransferase 
                EC 2.5.1.76                      cysteate synthase 
                EC 2.5.1.77                      7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase. Now EC 2.5.1.147, 5-amino-6-(D-ribitylamino)uracil—L-tyrosine 4-methylphenol transferase and EC 4.3.1.32, 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase. 
                EC 2.5.1.78                      6,7-dimethyl-8-ribityllumazine synthase 
                EC 2.5.1.79                      thermospermine synthase 
                EC 2.5.1.80                      7-dimethylallyltryptophan synthase 
                EC 2.5.1.81                      geranylfarnesyl diphosphate synthase 
                EC 2.5.1.82                      hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] 
                EC 2.5.1.83                      hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] 
                EC 2.5.1.84                      all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific] 
                EC 2.5.1.85                      all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] 
                EC 2.5.1.86                      trans,polycis-decaprenyl diphosphate synthase 
                EC 2.5.1.87                      ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] 
                EC 2.5.1.88                      trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] 
                EC 2.5.1.89                      tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] 
                EC 2.5.1.90                      all-trans-octaprenyl-diphosphate synthase 
                EC 2.5.1.91                      all-trans-decaprenyl-diphosphate synthase 
                EC 2.5.1.92                      (2Z,6Z)-farnesyl diphosphate synthase 
                EC 2.5.1.93                      4-hydroxybenzoate geranyltransferase 
                EC 2.5.1.94                      adenosyl-chloride synthase 
                EC 2.5.1.95                      xanthan ketal pyruvate transferase 
                EC 2.5.1.96                      4,4′-diapophytoene synthase 
                EC 2.5.1.97                      pseudaminic acid synthase 
                EC 2.5.1.98                      Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase 
                EC 2.5.1.99                       all-trans-phytoene synthase. The activity was an artifact caused by photoisomerization of the product of EC 2.5.1.32, 15-cis-phytoene synthase. 
                EC 2.5.1.100                      fumigaclavine A dimethylallyltransferase 
                EC 2.5.1.101                      N,N′-diacetyllegionaminate synthase 
                EC 2.5.1.102                      geranyl-pyrophosphate—olivetolic acid geranyltransferase 
                EC 2.5.1.103                      presqualene diphosphate synthase 
                EC 2.5.1.104                      N1-aminopropylagmatine synthase 
                EC 2.5.1.105                      7,8-dihydropterin-6-yl-methyl-4-(β-D-ribofuranosyl)aminobenzene 5′-phosphate synthase 
                EC 2.5.1.106                      tryprostatin B synthase 
                EC 2.5.1.107                      verruculogen prenyltransferase 
                EC 2.5.1.108                      2-(3-amino-3-carboxypropyl)histidine synthase 
                EC 2.5.1.109                      brevianamide F prenyltransferase (deoxybrevianamide E-forming) 
                EC 2.5.1.110                      12α,13α-dihydroxyfumitremorgin C prenyltransferase 
                EC 2.5.1.111                      4-hydroxyphenylpyruvate 3-dimethylallyltransferase 
                EC 2.5.1.112                      adenylate dimethylallyltransferase (ADP/ATP-dependent) 
                EC 2.5.1.113                      [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase 
                EC 2.5.1.114                      tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase 
                EC 2.5.1.115                      homogentisate phytyltransferase 
                EC 2.5.1.116                      homogentisate geranylgeranyltransferase 
                EC 2.5.1.117                      homogentisate solanesyltransferase 
                EC 2.5.1.118                      β-(isoxazolin-5-on-2-yl)-L-alanine synthase 
                EC 2.5.1.119                      β-(isoxazolin-5-on-4-yl)-L-alanine synthase 
                EC 2.5.1.120                      aminodeoxyfutalosine synthase 
                EC 2.5.1.121                      5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase 
                EC 2.5.1.122                      4-O-dimethylallyl-L-tyrosine synthase 
                EC 2.5.1.123                      flaviolin linalyltransferase 
                EC 2.5.1.124                      6-linalyl-2-O,3-dimethylflaviolin synthase 
                EC 2.5.1.125                      7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase 
                EC 2.5.1.126                      norspermine synthase 
                EC 2.5.1.127                      caldopentamine synthase 
                EC 2.5.1.128                      N4-bis(aminopropyl)spermidine synthase 
                EC 2.5.1.129                      flavin prenyltransferase 
                EC 2.5.1.130                      2-carboxy-1,4-naphthoquinone phytyltransferase 
                EC 2.5.1.131                      (4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase 
                EC 2.5.1.132                      3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase 
                EC 2.5.1.133                      bacteriochlorophyll a synthase 
                EC 2.5.1.134                      cystathionine β-synthase (O-acetyl-L-serine) 
                EC 2.5.1.135                      validamine 7-phosphate valienyltransferase 
                EC 2.5.1.136                      2-acylphloroglucinol 4-prenyltransferase 
                EC 2.5.1.137                      2-acyl-4-prenylphloroglucinol 6-prenyltransferase 
                EC 2.5.1.138                      coumarin 8-geranyltransferase 
                EC 2.5.1.139                      umbelliferone 6-dimethylallyltransferase 
                EC 2.5.1.140                      N-(2-amino-2-carboxyethyl)-L-glutamate synthase 
                EC 2.5.1.141                      heme o synthase 
                EC 2.5.1.142                      nerylneryl diphosphate synthase 
                EC 2.5.1.143                      pyridinium-3,5-biscarboxylic acid mononucleotide synthase 
                EC 2.5.1.144                      S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) 
                EC 2.5.1.145                      phosphatidylglycerol—prolipoprotein diacylglyceryl transferase 
                EC 2.5.1.146                      3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase 
                EC 2.5.1.147                      5-amino-6-(D-ribitylamino)uracil—L-tyrosine 4-hydroxyphenyl transferase 
                EC 2.5.1.148                      lycopaoctaene synthase 
                EC 2.5.1.149                      lycopene elongase/hydratase (flavuxanthin-forming) 
                EC 2.5.1.150                      lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) 
                EC 2.5.1.151                      alkylcobalamin dealkylase 
                EC 2.5.1.152                      D-histidine 2-aminobutanoyltransferase 
                EC 2.5.1.153                      adenosine tuberculosinyltransferase 
                EC 2.5.1.154                      corrinoid adenosyltransferase EutT 
                EC 2.5.1.155                      phosphoglycerol geranylfarnesyltransferase 
                EC 2.5.1.156                      geranylfarnesylglycerol-phosphate geranylfarnesyltransferase 
                EC 2.5.1.157                      rRNA small subunit aminocarboxypropyltransferase 
    EC 2.6  [+]      
        EC 2.6.1       []      
                EC 2.6.1.1                      aspartate transaminase 
                EC 2.6.1.2                      alanine transaminase 
                EC 2.6.1.3                      cysteine transaminase 
                EC 2.6.1.4                      glycine transaminase 
                EC 2.6.1.5                      tyrosine transaminase 
                EC 2.6.1.6                      leucine transaminase 
                EC 2.6.1.7                      kynurenine—oxoglutarate transaminase 
                EC 2.6.1.8                      2,5-diaminovalerate transaminase. This entry was found to be incorrect 
                EC 2.6.1.9                      histidinol-phosphate transaminase 
                EC 2.6.1.10                       D-aspartate transaminase. Now included with EC 2.6.1.21, D-amino-acid transaminase 
                EC 2.6.1.11                      acetylornithine transaminase 
                EC 2.6.1.12                      alanine—oxo-acid transaminase 
                EC 2.6.1.13                      ornithine aminotransferase 
                EC 2.6.1.14                      asparagine—oxo-acid transaminase 
                EC 2.6.1.15                      glutamine—pyruvate transaminase 
                EC 2.6.1.16                      glutamine—fructose-6-phosphate transaminase (isomerizing) 
                EC 2.6.1.17                      succinyldiaminopimelate transaminase 
                EC 2.6.1.18                      β-alanine—pyruvate transaminase 
                EC 2.6.1.19                      4-aminobutyrate—2-oxoglutarate transaminase 
                EC 2.6.1.20                       tyrosine—pyruvate transaminase 
                EC 2.6.1.21                      D-amino-acid transaminase 
                EC 2.6.1.22                      (S)-3-amino-2-methylpropionate transaminase 
                EC 2.6.1.23                      4-hydroxyglutamate transaminase 
                EC 2.6.1.24                      diiodotyrosine transaminase 
                EC 2.6.1.25                       thyroxine transaminase. Now included with EC 2.6.1.24 diiodotyrosine transaminase 
                EC 2.6.1.26                      thyroid-hormone transaminase 
                EC 2.6.1.27                      tryptophan transaminase 
                EC 2.6.1.28                      tryptophan—phenylpyruvate transaminase 
                EC 2.6.1.29                      diamine transaminase 
                EC 2.6.1.30                      pyridoxamine—pyruvate transaminase 
                EC 2.6.1.31                      pyridoxamine—oxaloacetate transaminase 
                EC 2.6.1.32                      valine—3-methyl-2-oxovalerate transaminase 
                EC 2.6.1.33                      dTDP-4-amino-4,6-dideoxy-D-glucose transaminase 
                EC 2.6.1.34                      UDP-N-acetylbacillosamine transaminase 
                EC 2.6.1.35                      glycine—oxaloacetate transaminase 
                EC 2.6.1.36                      L-lysine 6-transaminase 
                EC 2.6.1.37                      2-aminoethylphosphonate—pyruvate transaminase 
                EC 2.6.1.38                      histidine transaminase 
                EC 2.6.1.39                      2-aminoadipate transaminase 
                EC 2.6.1.40                      (R)-3-amino-2-methylpropionate—pyruvate transaminase 
                EC 2.6.1.41                      D-methionine—pyruvate transaminase 
                EC 2.6.1.42                      branched-chain-amino-acid transaminase 
                EC 2.6.1.43                      aminolevulinate transaminase 
                EC 2.6.1.44                      alanine—glyoxylate transaminase 
                EC 2.6.1.45                      serine—glyoxylate transaminase 
                EC 2.6.1.46                      diaminobutyrate—pyruvate transaminase 
                EC 2.6.1.47                      alanine—oxomalonate transaminase 
                EC 2.6.1.48                      5-aminovalerate transaminase 
                EC 2.6.1.49                      dihydroxyphenylalanine transaminase 
                EC 2.6.1.50                      glutamine—scyllo-inositol transaminase 
                EC 2.6.1.51                      serine—pyruvate transaminase 
                EC 2.6.1.52                      phosphoserine transaminase 
                EC 2.6.1.53                      glutamate synthase. Now EC 1.4.1.13, glutamate synthase (NADPH) 
                EC 2.6.1.54                      pyridoxamine-phosphate transaminase 
                EC 2.6.1.55                      taurine—2-oxoglutarate transaminase 
                EC 2.6.1.56                      1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase 
                EC 2.6.1.57                      aromatic-amino-acid transaminase 
                EC 2.6.1.58                      phenylalanine(histidine) transaminase 
                EC 2.6.1.59                      dTDP-4-amino-4,6-dideoxygalactose transaminase 
                EC 2.6.1.60                      aromatic-amino-acid—glyoxylate transaminase 
                EC 2.6.1.61                       (R)-3-amino-2-methylpropionate transaminase. Enzyme is identical to EC 2.6.1.40, (R)-3-amino-2-methylpropionate—pyruvate transaminase 
                EC 2.6.1.62                      adenosylmethionine—8-amino-7-oxononanoate transaminase 
                EC 2.6.1.63                      kynurenine—glyoxylate transaminase 
                EC 2.6.1.64                      glutamine—phenylpyruvate transaminase 
                EC 2.6.1.65                      N6-acetyl-β-lysine transaminase 
                EC 2.6.1.66                      valine—pyruvate transaminase 
                EC 2.6.1.67                      2-aminohexanoate transaminase 
                EC 2.6.1.68                      ornithine(lysine) transaminase. Now classified as EC 2.6.1.13, ornithine aminotransferase and EC 2.6.1.36, L-lysine 6-transaminase 
                EC 2.6.1.69                       N2-acetylornithine 5-transaminase. Enzyme is identical to EC 2.6.1.11, acetylornithine transaminase 
                EC 2.6.1.70                      aspartate—phenylpyruvate transaminase 
                EC 2.6.1.71                      lysine—pyruvate 6-transaminase 
                EC 2.6.1.72                      D-4-hydroxyphenylglycine transaminase 
                EC 2.6.1.73                      methionine—glyoxylate transaminase 
                EC 2.6.1.74                      cephalosporin-C transaminase 
                EC 2.6.1.75                      cysteine-conjugate transaminase 
                EC 2.6.1.76                      diaminobutyrate—2-oxoglutarate transaminase 
                EC 2.6.1.77                      taurine—pyruvate aminotransferase 
                EC 2.6.1.78                      aspartate—prephenate aminotransferase 
                EC 2.6.1.79                      glutamate—prephenate aminotransferase 
                EC 2.6.1.80                      nicotianamine aminotransferase 
                EC 2.6.1.81                      succinylornithine transaminase 
                EC 2.6.1.82                      putrescine—2-oxoglutarate transaminase 
                EC 2.6.1.83                      LL-diaminopimelate aminotransferase 
                EC 2.6.1.84                      arginine—pyruvate transaminase 
                EC 2.6.1.85                      aminodeoxychorismate synthase 
                EC 2.6.1.86                      2-amino-4-deoxychorismate synthase 
                EC 2.6.1.87                      UDP-4-amino-4-deoxy-L-arabinose aminotransferase 
                EC 2.6.1.88                      methionine transaminase 
                EC 2.6.1.89                      dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase 
                EC 2.6.1.90                      dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase 
                EC 2.6.1.91                      UDP-4-amino-4,6-dideoxy-N-acetyl-α-D-glucosamine transaminase. Identical to EC 2.6.1.34, UDP-N-acetylbacillosamine transaminase. 
                EC 2.6.1.92                      UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine transaminase 
                EC 2.6.1.93                      neamine transaminase 
                EC 2.6.1.94                      2′-deamino-2′-hydroxyneamine transaminase 
                EC 2.6.1.95                      neomycin C transaminase 
                EC 2.6.1.96                      4-aminobutyrate—pyruvate transaminase 
                EC 2.6.1.97                      archaeosine synthase 
                EC 2.6.1.98                      UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase 
                EC 2.6.1.99                      L-tryptophan—pyruvate aminotransferase 
                EC 2.6.1.100                      L-glutamine:2-deoxy-scyllo-inosose aminotransferase 
                EC 2.6.1.101                      L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase 
                EC 2.6.1.102                      GDP-perosamine synthase 
                EC 2.6.1.103                      (S)-3,5-dihydroxyphenylglycine transaminase 
                EC 2.6.1.104                      3-dehydro-glucose-6-phosphate—glutamate transaminase 
                EC 2.6.1.105                      lysine—8-amino-7-oxononanoate transaminase 
                EC 2.6.1.106                      dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase 
                EC 2.6.1.107                      β-methylphenylalanine transaminase 
                EC 2.6.1.108                      (5-formylfuran-3-yl)methyl phosphate transaminase 
                EC 2.6.1.109                      8-amino-3,8-dideoxy-α-D-manno-octulosonate transaminase 
                EC 2.6.1.110                      dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase 
                EC 2.6.1.111                      3-aminobutanoyl-CoA transaminase 
                EC 2.6.1.112                      (S)-ureidoglycine—glyoxylate transaminase 
                EC 2.6.1.113                      putrescine—pyruvate transaminase 
                EC 2.6.1.114                      8-demethyl-8-aminoriboflavin-5′-phosphate synthase 
                EC 2.6.1.115                      5-hydroxydodecatetraenal 1-aminotransferase 
                EC 2.6.1.116                      6-aminohexanoate aminotransferase 
                EC 2.6.1.117                      L-glutamine—4-(methylsulfanyl)-2-oxobutanoate aminotransferase 
                EC 2.6.1.118                      [amino-group carrier protein]-γ-(L-lysyl)-L-glutamate aminotransferase 
                EC 2.6.1.119                      vanillin aminotransferase 
                EC 2.6.1.120                      β-alanine—2-oxoglutarate transaminase 
                EC 2.6.1.121                      8-amino-7-oxononanoate carboxylating dehydrogenase 
                EC 2.6.1.122                      UDP-N-acetyl-3-dehydro-α-D-glucosamine 3-aminotranferase 
                EC 2.6.1.123                      4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) 
                EC 2.6.1.124                      [amino-group carrier protein]-γ-(L-ornithyl)-L-glutamate aminotransferase 
        EC 2.6.2       []    Amidinotransferases (deleted sub-subclass) 
                EC 2.6.2.1                      now EC 2.1.4.1 glycine amidinotransferase 
        EC 2.6.3       []    Oximinotransferases 
                EC 2.6.3.1                      oximinotransferase 
        EC 2.6.99       []    Transferring other nitrogenous groups 
                EC 2.6.99.1                      dATP(dGTP)—DNA purinetransferase 
                EC 2.6.99.2                      pyridoxine 5′-phosphate synthase 
                EC 2.6.99.3                      O-ureido-L-serine synthase 
                EC 2.6.99.4                      N6-L-threonylcarbamoyladenine synthase. Now EC 2.3.1.234, N6-L-threonylcarbamoyladenine synthase. 
    EC 2.7  [+]      
        EC 2.7.1       []    Phosphotransferases with an alcohol group as acceptor 
                EC 2.7.1.1                      hexokinase 
                EC 2.7.1.2                      glucokinase 
                EC 2.7.1.3                      ketohexokinase 
                EC 2.7.1.4                      fructokinase 
                EC 2.7.1.5                      rhamnulokinase 
                EC 2.7.1.6                      galactokinase 
                EC 2.7.1.7                      mannokinase 
                EC 2.7.1.8                      glucosamine kinase 
                EC 2.7.1.9                       acetylaminodeoxyglucose kinase 
                EC 2.7.1.10                      phosphoglucokinase 
                EC 2.7.1.11                      6-phosphofructokinase 
                EC 2.7.1.12                      gluconokinase 
                EC 2.7.1.13                      dehydrogluconokinase 
                EC 2.7.1.14                      sedoheptulokinase 
                EC 2.7.1.15                      ribokinase 
                EC 2.7.1.16                      ribulokinase 
                EC 2.7.1.17                      xylulokinase 
                EC 2.7.1.18                      phosphoribokinase 
                EC 2.7.1.19                      phosphoribulokinase 
                EC 2.7.1.20                      adenosine kinase 
                EC 2.7.1.21                      thymidine kinase 
                EC 2.7.1.22                      ribosylnicotinamide kinase 
                EC 2.7.1.23                      NAD+ kinase 
                EC 2.7.1.24                      dephospho-CoA kinase 
                EC 2.7.1.25                      adenylyl-sulfate kinase 
                EC 2.7.1.26                      riboflavin kinase 
                EC 2.7.1.27                      erythritol kinase (D-erythritol 4-phosphate-forming) 
                EC 2.7.1.28                      triokinase 
                EC 2.7.1.29                      glycerone kinase 
                EC 2.7.1.30                      glycerol kinase 
                EC 2.7.1.31                      glycerate 3-kinase 
                EC 2.7.1.32                      choline kinase 
                EC 2.7.1.33                      pantothenate kinase 
                EC 2.7.1.34                      pantetheine kinase 
                EC 2.7.1.35                      pyridoxal kinase 
                EC 2.7.1.36                      mevalonate kinase 
                EC 2.7.1.37                      protein kinase. Now divided into EC 2.7.11.1 (non-specific serine/threonine protein kinase), EC 2.7.11.8 (Fas-activated serine/threonine kinase), EC 2.7.11.9 (Goodpasture-antigen-binding protein kinase), EC 2.7.11.10 (IκB kinase), EC 2.7.11.11 (cAMP-dependent protein kinase), EC 2.7.11.12 (cGMP-dependent protein kinase), EC 2.7.11.13 (protein kinase C), EC 2.7.11.21 (polo kinase), EC 2.7.11.22 (cyclin-dependent kinase), EC 2.7.11.24 (mitogen-activated protein kinase), EC 2.7.11.25 (mitogen-activated protein kinase kinase kinase), EC 2.7.11.30 (receptor protein serine/threonine kinase) and EC 2.7.12.1 (dual-specificity kinase) 
                EC 2.7.1.38                      phosphorylase kinase. Now EC 2.7.11.19, phosphorylase kinase 
                EC 2.7.1.39                      homoserine kinase 
                EC 2.7.1.40                      pyruvate kinase 
                EC 2.7.1.41                      glucose-1-phosphate phosphodismutase 
                EC 2.7.1.42                      riboflavin phosphotransferase 
                EC 2.7.1.43                      glucuronokinase 
                EC 2.7.1.44                      galacturonokinase 
                EC 2.7.1.45                      2-dehydro-3-deoxygluconokinase 
                EC 2.7.1.46                      L-arabinokinase 
                EC 2.7.1.47                      D-ribulokinase 
                EC 2.7.1.48                      uridine/cytidine kinase 
                EC 2.7.1.49                      hydroxymethylpyrimidine kinase 
                EC 2.7.1.50                      hydroxyethylthiazole kinase 
                EC 2.7.1.51                      L-fuculokinase 
                EC 2.7.1.52                      fucokinase 
                EC 2.7.1.53                      L-xylulokinase 
                EC 2.7.1.54                      D-arabinokinase 
                EC 2.7.1.55                      allose kinase 
                EC 2.7.1.56                      1-phosphofructokinase 
                EC 2.7.1.57                       mannitol kinase 
                EC 2.7.1.58                      2-dehydro-3-deoxygalactonokinase 
                EC 2.7.1.59                      N-acetylglucosamine kinase 
                EC 2.7.1.60                      N-acylmannosamine kinase 
                EC 2.7.1.61                      acyl-phosphate—hexose phosphotransferase 
                EC 2.7.1.62                      phosphoramidate—hexose phosphotransferase 
                EC 2.7.1.63                      polyphosphate—glucose phosphotransferase 
                EC 2.7.1.64                      inositol 3-kinase 
                EC 2.7.1.65                      scyllo-inosamine 4-kinase 
                EC 2.7.1.66                      undecaprenol kinase 
                EC 2.7.1.67                      1-phosphatidylinositol 4-kinase 
                EC 2.7.1.68                      1-phosphatidylinositol-4-phosphate 5-kinase 
                EC 2.7.1.69                      protein-Nπ-phosphohistidine—sugar phosphotransferase, now covered by EC 2.7.1.191 protein-Nπ-phosphohistidine—D-mannose phosphotransferase, EC 2.7.1.192 protein-Nπ-phosphohistidine—N-acetylmuramate phosphotransferase, EC 2.7.1.193 protein-Nπ-phosphohistidine—N-acetyl-D-glucosamine phosphotransferase, EC 2.7.1.194 protein-Nπ-phosphohistidine—L-ascorbate phosphotransferase, EC 2.7.1.195 protein-Nπ-phosphohistidine—2-O-α-mannosyl-D-glycerate phosphotransferase, EC 2.7.1.196 protein-Nπ-phosphohistidine—N,N′-diacetylchitobiose phosphotransferase, EC 2.7.1.197 protein-Nπ-phosphohistidine—D-mannitol phosphotransferase, EC 2.7.1.198 protein-Nπ-phosphohistidine—D-sorbitol phosphotransferase, EC 2.7.1.199 protein-Nπ-phosphohistidine—D-glucose phosphotransferase, EC 2.7.1.200 protein-Nπ-phosphohistidine—galactitol phosphotransferase, EC 2.7.1.201 protein-Nπ-phosphohistidine—trehalose phosphotransferase, EC 2.7.1.202 protein-Nπ-phosphohistidine—D-fructose phosphotransferase, EC 2.7.1.203 protein-Nπ-phosphohistidine—D-glucosaminate phosphotransferase, EC 2.7.1.204 protein-Nπ-phosphohistidine—D-galactose phosphotransferase, EC 2.7.1.205 protein-Nπ-phosphohistidine—cellobiose phosphotransferase, EC 2.7.1.206 protein-Nπ-phosphohistidine—L-sorbose phosphotransferase, EC 2.7.1.207 protein-Nπ-phosphohistidine—lactose phosphotransferase and EC 2.7.1.208 protein-Nπ-phosphohistidine—maltose phosphotransferase. 
                EC 2.7.1.70                       protamine kinase. Now included in EC 2.7.11.1, non-specific serine/threonine protein kinase 
                EC 2.7.1.71                      shikimate kinase 
                EC 2.7.1.72                      streptomycin 6-kinase 
                EC 2.7.1.73                      inosine kinase 
                EC 2.7.1.74                      deoxycytidine kinase 
                EC 2.7.1.75                       thymidine kinase. Now EC 2.7.1.21 thymidine kinase 
                EC 2.7.1.76                      2′-deoxyadenosine kinase 
                EC 2.7.1.77                      nucleoside phosphotransferase 
                EC 2.7.1.78                      polynucleotide 5′-hydroxyl-kinase 
                EC 2.7.1.79                      diphosphate—glycerol phosphotransferase 
                EC 2.7.1.80                      diphosphate—serine phosphotransferase 
                EC 2.7.1.81                      hydroxylysine kinase 
                EC 2.7.1.82                      ethanolamine kinase 
                EC 2.7.1.83                      pseudouridine kinase 
                EC 2.7.1.84                      alkylglycerone kinase 
                EC 2.7.1.85                      β-glucoside kinase 
                EC 2.7.1.86                      NADH kinase 
                EC 2.7.1.87                      streptomycin 3′′-kinase 
                EC 2.7.1.88                      dihydrostreptomycin-6-phosphate 3′α-kinase 
                EC 2.7.1.89                      thiamine kinase 
                EC 2.7.1.90                      diphosphate—fructose-6-phosphate 1-phosphotransferase 
                EC 2.7.1.91                      sphingosine kinase 
                EC 2.7.1.92                      5-dehydro-2-deoxygluconokinase 
                EC 2.7.1.93                      alkylglycerol kinase 
                EC 2.7.1.94                      acylglycerol kinase 
                EC 2.7.1.95                      kanamycin kinase 
                EC 2.7.1.96                       NADH kinase. Now included with EC 2.7.1.86 NADH kinase 
                EC 2.7.1.97                      opsin kinase. Identical with EC 2.7.11.14, rhodopsin kinase 
                EC 2.7.1.98                       phosphoenolpyruvate—fructose phosphotransferase 
                EC 2.7.1.99                      [pyruvate dehydrogenase (lipoamide)] kinase. Now EC 2.7.11.2, [pyruvate dehydrogenase (acetyl-transferring)] kinase 
                EC 2.7.1.100                      S-methyl-5-thioribose kinase 
                EC 2.7.1.101                      tagatose kinase 
                EC 2.7.1.102                      hamamelose kinase 
                EC 2.7.1.103                      viomycin kinase 
                EC 2.7.1.104                      diphosphate—protein phosphotransferase. Now EC 2.7.99.1, triphosphate—protein phosphotransferase 
                EC 2.7.1.105                      6-phosphofructo-2-kinase 
                EC 2.7.1.106                      glucose-1,6-bisphosphate synthase 
                EC 2.7.1.107                      diacylglycerol kinase (ATP) 
                EC 2.7.1.108                      dolichol kinase 
                EC 2.7.1.109                      [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase. Now EC 2.7.11.31, [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase 
                EC 2.7.1.110                      dephospho-[reductase kinase] kinase. Now EC 2.7.11.3, dephospho-[reductase kinase] kinase 
                EC 2.7.1.111                      [acetyl-CoA carboxylase] kinase. Now listed as EC 2.7.11.27, [acetyl-CoA carboxylase] kinase 
                EC 2.7.1.112                      protein-tyrosine kinase. Now EC 2.7.10.2, non-specific protein-tyrosine kinase 
                EC 2.7.1.113                      deoxyguanosine kinase 
                EC 2.7.1.114                      AMP—thymidine kinase 
                EC 2.7.1.115                      [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase. Now EC 2.7.11.4, [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase 
                EC 2.7.1.116                      [isocitrate dehydrogenase (NADP+)] kinase. Now EC 2.7.11.5, [isocitrate dehydrogenase (NADP+)] kinase 
                EC 2.7.1.117                      myosin-light-chain kinase. Now EC 2.7.11.18, myosin-light-chain kinase 
                EC 2.7.1.118                      ADP—thymidine kinase 
                EC 2.7.1.119                      hygromycin-B 7′′-O-kinase 
                EC 2.7.1.120                      caldesmon kinase. Now EC 2.7.11.17, Ca2+/calmodulin-dependent protein kinase 
                EC 2.7.1.121                      phosphoenolpyruvate—glycerone phosphotransferase 
                EC 2.7.1.122                      xylitol kinase 
                EC 2.7.1.123                      Ca2+/calmodulin-dependent protein kinase. Now EC 2.7.11.17, Ca2+/calmodulin-dependent protein kinase 
                EC 2.7.1.124                      [tyrosine 3-monooxygenase] kinase. Now EC 2.7.11.6, [tyrosine 3-monooxygenase] kinase 
                EC 2.7.1.125                      rhodopsin kinase. Now EC 2.7.11.14, rhodopsin kinase 
                EC 2.7.1.126                      [β-adrenergic-receptor] kinase. Now EC 2.7.11.15, β-adrenergic-receptor kinase 
                EC 2.7.1.127                      inositol-trisphosphate 3-kinase 
                EC 2.7.1.128                      [acetyl-CoA carboxylase] kinase. Now EC 2.7.11.27, [acetyl-CoA carboxylase] kinase 
                EC 2.7.1.129                      [myosin-heavy-chain] kinase. Now EC 2.7.11.7, myosin-heavy-chain kinase 
                EC 2.7.1.130                      tetraacyldisaccharide 4′-kinase 
                EC 2.7.1.131                      [low-density-lipoprotein] kinase. Now EC 2.7.11.29, low-density-lipoprotein receptor kinase 
                EC 2.7.1.132                      tropomyosin kinase. Now EC 2.7.11.28, tropomyosin kinase 
                EC 2.7.1.133                       inositol-trisphosphate 6-kinase. Now included with EC 2.7.1.134, inositol-tetrakisphosphate 1-kinase 
                EC 2.7.1.134                      inositol-tetrakisphosphate 1-kinase 
                EC 2.7.1.135                      [tau-protein] kinase. Now EC 2.7.11.26, tau-protein kinase 
                EC 2.7.1.136                      macrolide 2′-kinase 
                EC 2.7.1.137                      phosphatidylinositol 3-kinase 
                EC 2.7.1.138                      ceramide kinase 
                EC 2.7.1.139                       inositol-trisphosphate 5-kinase. Now included with EC 2.7.1.134, inositol-tetrakisphosphate 1-kinase 
                EC 2.7.1.140                      inositol-tetrakisphosphate 5-kinase 
                EC 2.7.1.141                      [RNA-polymerase]-subunit kinase. Now EC 2.7.11.23, [RNA-polymerase]-subunit kinase 
                EC 2.7.1.142                      glycerol-3-phosphate—glucose phosphotransferase 
                EC 2.7.1.143                      diphosphate-purine nucleoside kinase 
                EC 2.7.1.144                      tagatose-6-phosphate kinase 
                EC 2.7.1.145                      deoxynucleoside kinase 
                EC 2.7.1.146                      ADP-specific phosphofructokinase 
                EC 2.7.1.147                      ADP-specific glucose/glucosamine kinase 
                EC 2.7.1.148                      4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol kinase 
                EC 2.7.1.149                      1-phosphatidylinositol-5-phosphate 4-kinase 
                EC 2.7.1.150                      1-phosphatidylinositol-3-phosphate 5-kinase 
                EC 2.7.1.151                      inositol-polyphosphate multikinase 
                EC 2.7.1.152                      inositol-hexakisphosphate kinase. Now EC 2.7.4.21, inositol-hexakisphosphate kinase 
                EC 2.7.1.153                      phosphatidylinositol-4,5-bisphosphate 3-kinase 
                EC 2.7.1.154                      phosphatidylinositol-4-phosphate 3-kinase 
                EC 2.7.1.155                      diphosphoinositol-pentakisphosphate kinase. Now EC 2.7.4.24, diphosphoinositol-pentakisphosphate kinase. The enzyme had been incorrectly classified as the reaction involves transfer of a phospho group to another phospho group (EC 2.7.4) rather than to an hydroxy group (EC 2.7.1) 
                EC 2.7.1.156                      adenosylcobinamide kinase 
                EC 2.7.1.157                      N-acetylgalactosamine kinase 
                EC 2.7.1.158                      inositol-pentakisphosphate 2-kinase 
                EC 2.7.1.159                      inositol-1,3,4-trisphosphate 5/6-kinase 
                EC 2.7.1.160                      2′-phosphotransferase 
                EC 2.7.1.161                      CTP-dependent riboflavin kinase 
                EC 2.7.1.162                      N-acetylhexosamine 1-kinase 
                EC 2.7.1.163                      hygromycin B 4-O-kinase 
                EC 2.7.1.164                      O-phosphoseryl-tRNASec kinase 
                EC 2.7.1.165                      glycerate 2-kinase 
                EC 2.7.1.166                      3-deoxy-D-manno-octulosonic acid kinase 
                EC 2.7.1.167                      D-glycero-β-D-manno-heptose-7-phosphate kinase 
                EC 2.7.1.168                      D-glycero-α-D-manno-heptose-7-phosphate kinase 
                EC 2.7.1.169                      pantoate kinase 
                EC 2.7.1.170                      anhydro-N-acetylmuramic acid kinase 
                EC 2.7.1.171                      protein-fructosamine 3-kinase 
                EC 2.7.1.172                      protein-ribulosamine 3-kinase 
                EC 2.7.1.173                      nicotinate riboside kinase 
                EC 2.7.1.174                      diacylglycerol kinase (CTP) 
                EC 2.7.1.175                      maltokinase 
                EC 2.7.1.176                      UDP-N-acetylglucosamine kinase 
                EC 2.7.1.177                      L-threonine kinase 
                EC 2.7.1.178                      2-dehydro-3-deoxyglucono/galactono-kinase  
                EC 2.7.1.179                      kanosamine kinase 
                EC 2.7.1.180                      FAD:protein FMN transferase 
                EC 2.7.1.181                      polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol kinase 
                EC 2.7.1.182                      phytol kinase 
                EC 2.7.1.183                      glycoprotein-mannosyl O6-kinase 
                EC 2.7.1.184                      sulfofructose kinase 
                EC 2.7.1.185                      mevalonate 3-kinase 
                EC 2.7.1.186                      mevalonate-3-phosphate 5-kinase 
                EC 2.7.1.187                      acarbose 7IV-phosphotransferase 
                EC 2.7.1.188                      2-epi-5-epi-valiolone 7-kinase 
                EC 2.7.1.189                      autoinducer-2 kinase 
                EC 2.7.1.190                      aminoglycoside 2′′-phosphotransferase 
                EC 2.7.1.191                      protein-Nπ-phosphohistidine—D-mannose phosphotransferase 
                EC 2.7.1.192                      protein-Nπ-phosphohistidine—N-acetylmuramate phosphotransferase 
                EC 2.7.1.193                      protein-Nπ-phosphohistidine—N-acetyl-D-glucosamine phosphotransferase 
                EC 2.7.1.194                      protein-Nπ-phosphohistidine—L-ascorbate phosphotransferase 
                EC 2.7.1.195                      protein-Nπ-phosphohistidine—2-O-α-mannosyl-D-glycerate phosphotransferase 
                EC 2.7.1.196                      protein-Nπ-phosphohistidine—N,N′-diacetylchitobiose phosphotransferase 
                EC 2.7.1.197                      protein-Nπ-phosphohistidine—D-mannitol phosphotransferase 
                EC 2.7.1.198                      protein-Nπ-phosphohistidine—D-sorbitol phosphotransferase 
                EC 2.7.1.199                      protein-Nπ-phosphohistidine—D-glucose phosphotransferase 
                EC 2.7.1.200                      protein-Nπ-phosphohistidine—galactitol phosphotransferase 
                EC 2.7.1.201                      protein-Nπ-phosphohistidine—trehalose phosphotransferase 
                EC 2.7.1.202                      protein-Nπ-phosphohistidine—D-fructose phosphotransferase 
                EC 2.7.1.203                      protein-Nπ-phosphohistidine—D-glucosaminate phosphotransferase 
                EC 2.7.1.204                      protein-Nπ-phosphohistidine—D-galactose phosphotransferase 
                EC 2.7.1.205                      protein-Nπ-phosphohistidine—cellobiose phosphotransferase 
                EC 2.7.1.206                      protein-Nπ-phosphohistidine—L-sorbose phosphotransferase 
                EC 2.7.1.207                      protein-Nπ-phosphohistidine—lactose phosphotransferase 
                EC 2.7.1.208                      protein-Nπ-phosphohistidine—maltose phosphotransferase 
                EC 2.7.1.209                      L-erythrulose 1-kinase 
                EC 2.7.1.210                      D-erythrulose 4-kinase 
                EC 2.7.1.211                      protein-Nπ-phosphohistidine—sucrose phosphotransferase 
                EC 2.7.1.212                      α-D-ribose-1-phosphate 5-kinase (ADP) 
                EC 2.7.1.213                      cytidine kinase 
                EC 2.7.1.214                      C7-cyclitol 7-kinase 
                EC 2.7.1.215                      erythritol kinase (D-erythritol 1-phosphate-forming) 
                EC 2.7.1.216                      farnesol kinase 
                EC 2.7.1.217                      3-dehydrotetronate 4-kinase 
                EC 2.7.1.218                      fructoselysine 6-kinase 
                EC 2.7.1.219                      D-threonate 4-kinase 
                EC 2.7.1.220                      D-erythronate 4-kinase 
                EC 2.7.1.221                      N-acetylmuramate 1-kinase 
                EC 2.7.1.222                      4-hydroxytryptamine kinase 
                EC 2.7.1.223                      aminoimidazole riboside kinase 
                EC 2.7.1.224                      cytidine diphosphoramidate kinase 
                EC 2.7.1.225                      L-serine kinase (ATP) 
                EC 2.7.1.226                      L-serine kinase (ADP) 
                EC 2.7.1.227                      inositol phosphorylceramide synthase 
                EC 2.7.1.228                      mannosyl-inositol-phosphoceramide inositolphosphotransferase 
                EC 2.7.1.229                      deoxyribokinase 
                EC 2.7.1.230                      amicoumacin kinase 
                EC 2.7.1.231                      3-oxoisoapionate kinase 
                EC 2.7.1.232                      levoglucosan kinase 
                EC 2.7.1.233                      apulose kinase 
                EC 2.7.1.234                      D-tagatose-1-phosphate kinase 
                EC 2.7.1.235                      lipopolysaccharide core heptose(I) kinase 
                EC 2.7.1.236                      NAD+ 3′-kinase 
                EC 2.7.1.237                      GTP-dependent dephospho-CoA kinase 
                EC 2.7.1.238                      phenol phosphorylase 
                EC 2.7.1.239                      α-D-ribose-1-phosphate 5-kinase (ATP) 
        EC 2.7.2       []    Phosphotransferases with a carboxy group as acceptor 
                EC 2.7.2.1                      acetate kinase 
                EC 2.7.2.2                      carbamate kinase 
                EC 2.7.2.3                      phosphoglycerate kinase 
                EC 2.7.2.4                      aspartate kinase 
                EC 2.7.2.5                      carbamoyl-phosphate synthase (ammonia). Now EC 6.3.4.16, carbamoyl-phosphate synthase (ammonia) 
                EC 2.7.2.6                      formate kinase 
                EC 2.7.2.7                      butyrate kinase 
                EC 2.7.2.8                      acetylglutamate kinase 
                EC 2.7.2.9                      carbamoyl-phosphate synthase (glutamine). Now EC 6.3.5.5, carbamoyl-phosphate synthase (glutamine-hydrolysing) 
                EC 2.7.2.10                      phosphoglycerate kinase (GTP) 
                EC 2.7.2.11                      glutamate 5-kinase 
                EC 2.7.2.12                      acetate kinase (diphosphate) 
                EC 2.7.2.13                      glutamate 1-kinase. Now known to be due to the activities of EC 6.1.1.17, glutamate—tRNA ligase, EC 1.2.1.70, glutamyl-tRNA reductase and EC 5.4.3.8,  
                EC 2.7.2.14                      branched-chain-fatty-acid kinase 
                EC 2.7.2.15                      propionate kinase 
                EC 2.7.2.16                      2-phosphoglycerate kinase 
                EC 2.7.2.17                      [amino-group carrier protein]-L-2-aminoadipate 6-kinase 
                EC 2.7.2.18                      fatty acid kinase 
                EC 2.7.2.19                      [amino-group carrier protein]-L-glutamate 6-kinase 
        EC 2.7.3       []    Phosphotransferases with a nitrogenous group as acceptor 
                EC 2.7.3.1                      guanidinoacetate kinase 
                EC 2.7.3.2                      creatine kinase 
                EC 2.7.3.3                      arginine kinase 
                EC 2.7.3.4                      taurocyamine kinase 
                EC 2.7.3.5                      lombricine kinase 
                EC 2.7.3.6                      hypotaurocyamine kinase 
                EC 2.7.3.7                      opheline kinase 
                EC 2.7.3.8                      ammonia kinase 
                EC 2.7.3.9                      phosphoenolpyruvate—protein phosphotransferase 
                EC 2.7.3.10                      agmatine kinase 
                EC 2.7.3.11                      protein-histidine pros-kinase. Now EC 2.7.13.1, protein-histidine pros-kinase 
                EC 2.7.3.12                      protein-histidine tele-kinase. Now EC 2.7.13.2, protein-histidine tele-kinase 
                EC 2.7.3.13                      glutamine kinase 
        EC 2.7.4       []    Phosphotransferases with a phosphate group as acceptor 
                EC 2.7.4.1                      ATP-polyphosphate phosphotransferase 
                EC 2.7.4.2                      phosphomevalonate kinase 
                EC 2.7.4.3                      adenylate kinase 
                EC 2.7.4.4                      nucleoside-phosphate kinase 
                EC 2.7.4.5                       deoxycytidylate kinase. Now included with EC 2.7.4.14 cytidylate kinase 
                EC 2.7.4.6                      nucleoside-diphosphate kinase 
                EC 2.7.4.7                      phosphooxymethylpyrimidine kinase 
                EC 2.7.4.8                      guanylate kinase 
                EC 2.7.4.9                      dTMP kinase 
                EC 2.7.4.10                      nucleoside-triphosphate—adenylate kinase 
                EC 2.7.4.11                      (deoxy)adenylate kinase 
                EC 2.7.4.12                      T2-induced deoxynucleotide kinase 
                EC 2.7.4.13                      (deoxy)nucleoside-phosphate kinase 
                EC 2.7.4.14                      UMP/CMP kinase 
                EC 2.7.4.15                      thiamine-diphosphate kinase 
                EC 2.7.4.16                      thiamine-phosphate kinase 
                EC 2.7.4.17                      3-phosphoglyceroyl-phosphate—polyphosphate phosphotransferase 
                EC 2.7.4.18                      farnesyl-diphosphate kinase 
                EC 2.7.4.19                      5-methyldeoxycytidine-5′-phosphate kinase 
                EC 2.7.4.20                      dolichyl-diphosphate—polyphosphate phosphotransferase 
                EC 2.7.4.21                      inositol-hexakisphosphate 5-kinase 
                EC 2.7.4.22                      UMP kinase 
                EC 2.7.4.23                      ribose 1,5-bisphosphate phosphokinase 
                EC 2.7.4.24                      diphosphoinositol-pentakisphosphate 1-kinase 
                EC 2.7.4.25                      (d)CMP kinase 
                EC 2.7.4.26                      isopentenyl phosphate kinase 
                EC 2.7.4.27                      [pyruvate, phosphate dikinase]-phosphate phosphotransferase 
                EC 2.7.4.28                      [pyruvate, water dikinase]-phosphate phosphotransferase 
                EC 2.7.4.29                      Kdo2-lipid A phosphotransferase 
                EC 2.7.4.30                      lipid A phosphoethanolamine transferase. Now EC 2.7.8.43, lipid A phosphoethanolamine transferase 
                EC 2.7.4.31                      [5-(aminomethyl)furan-3-yl]methyl phosphate kinase 
                EC 2.7.4.32                      farnesyl phosphate kinase 
                EC 2.7.4.33                      AMP-polyphosphate phosphotransferase 
                EC 2.7.4.34                      GDP-polyphosphate phosphotransferase 
        EC 2.7.5       []    Phosphotransferases with regeneration of donors, apparently catalysing intramolecular transfers (deleted sub-subclass) 
                EC 2.7.5.1                      phosphoglucomutase. Now EC 5.4.2.2, phosphoglucomutase 
                EC 2.7.5.2                      acetylglucosamine phosphomutase. Now EC 5.4.2.3, phosphoacetylglucosamine mutase 
                EC 2.7.5.3                      phosphoglyceromutase. Now EC 5.4.2.1, phosphoglycerate mutase 
                EC 2.7.5.4                      bisphosphoglyceromutase. Now EC 5.4.2.4, bisphosphoglycerate mutase 
                EC 2.7.5.5                      phosphoglucomutase (glucose-cofactor). Now EC 5.4.2.5, phosphoglucomutase (glucose-cofactor) 
                EC 2.7.5.6                      phosphopentomutase. Now EC 5.4.2.7, phosphopentomutase 
                EC 2.7.5.7                      phosphomannomutase. Now EC 5.4.2.8, phosphomannomutase 
        EC 2.7.6       []    Diphosphotransferases 
                EC 2.7.6.1                      ribose-phosphate diphosphokinase 
                EC 2.7.6.2                      thiamine diphosphokinase 
                EC 2.7.6.3                      2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 
                EC 2.7.6.4                      nucleotide diphosphokinase 
                EC 2.7.6.5                      GTP diphosphokinase 
        EC 2.7.7       []    Nucleotidyltransferases 
                EC 2.7.7.1                      nicotinamide-nucleotide adenylyltransferase 
                EC 2.7.7.2                      FAD synthase 
                EC 2.7.7.3                      pantetheine-phosphate adenylyltransferase 
                EC 2.7.7.4                      sulfate adenylyltransferase 
                EC 2.7.7.5                      sulfate adenylyltransferase (ADP) 
                EC 2.7.7.6                      DNA-directed RNA polymerase 
                EC 2.7.7.7                      DNA-directed DNA polymerase 
                EC 2.7.7.8                      polyribonucleotide nucleotidyltransferase 
                EC 2.7.7.9                      UTP—glucose-1-phosphate uridylyltransferase 
                EC 2.7.7.10                      UTP—hexose-1-phosphate uridylyltransferase 
                EC 2.7.7.11                      UTP—xylose-1-phosphate uridylyltransferase 
                EC 2.7.7.12                      UDP-glucose—hexose-1-phosphate uridylyltransferase 
                EC 2.7.7.13                      mannose-1-phosphate guanylyltransferase 
                EC 2.7.7.14                      ethanolamine-phosphate cytidylyltransferase 
                EC 2.7.7.15                      choline-phosphate cytidylyltransferase 
                EC 2.7.7.16                      ribonuclease. Now EC 3.1.27.5, pancreatic ribonuclease 
                EC 2.7.7.17                      ribonuclease. Now EC 3.1.27.1, ribonuclease T2 
                EC 2.7.7.18                      nicotinate-nucleotide adenylyltransferase 
                EC 2.7.7.19                      polynucleotide adenylyltransferase 
                EC 2.7.7.20                      sRNA nucleotidyl transferase. This entry was identical with EC 2.7.7.25, tRNA adenylyltransferase 
                EC 2.7.7.21                      tRNA cytidylyltransferase. Now EC 2.7.7.72, CCA tRNA nucleotidyltransferase 
                EC 2.7.7.22                      mannose-1-phosphate guanylyltransferase (GDP) 
                EC 2.7.7.23                      UDP-N-acetylglucosamine diphosphorylase 
                EC 2.7.7.24                      glucose-1-phosphate thymidylyltransferase 
                EC 2.7.7.25                      tRNA adenylyltransferase. Now EC 2.7.7.72, CCA tRNA nucleotidyltransferase 
                EC 2.7.7.26                      nicotinate-nucleotide adenylyltransferase. Now EC 3.1.27.3, ribonuclease T1 
                EC 2.7.7.27                      glucose-1-phosphate adenylyltransferase 
                EC 2.7.7.28                      nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase 
                EC 2.7.7.29                       hexose-1-phosphate guanylyltransferase. Enzyme is not specific for GTP and therefore is identical to EC 2.7.7.28, nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase 
                EC 2.7.7.30                      fucose-1-phosphate guanylyltransferase 
                EC 2.7.7.31                      DNA nucleotidylexotransferase 
                EC 2.7.7.32                      galactose-1-phosphate thymidylyltransferase 
                EC 2.7.7.33                      glucose-1-phosphate cytidylyltransferase 
                EC 2.7.7.34                      glucose-1-phosphate guanylyltransferase 
                EC 2.7.7.35                      ADP ribose phosphorylase 
                EC 2.7.7.36                      aldose-1-phosphate adenylyltransferase 
                EC 2.7.7.37                      aldose-1-phosphate nucleotidyltransferase 
                EC 2.7.7.38                      3-deoxy-manno-octulosonate cytidylyltransferase 
                EC 2.7.7.39                      glycerol-3-phosphate cytidylyltransferase 
                EC 2.7.7.40                      D-ribitol-5-phosphate cytidylyltransferase 
                EC 2.7.7.41                      phosphatidate cytidylyltransferase 
                EC 2.7.7.42                      [glutamine synthetase] adenylyltransferase 
                EC 2.7.7.43                      N-acylneuraminate cytidylyltransferase 
                EC 2.7.7.44                      glucuronate-1-phosphate uridylyltransferase 
                EC 2.7.7.45                      guanosine-triphosphate guanylyltransferase 
                EC 2.7.7.46                      gentamicin 2′′-nucleotidyltransferase 
                EC 2.7.7.47                      streptomycin 3′′-adenylyltransferase 
                EC 2.7.7.48                      RNA-directed RNA polymerase 
                EC 2.7.7.49                      RNA-directed DNA polymerase 
                EC 2.7.7.50                      mRNA guanylyltransferase 
                EC 2.7.7.51                      adenylylsulfate—ammonia adenylyltransferase 
                EC 2.7.7.52                      RNA uridylyltransferase 
                EC 2.7.7.53                      ATP adenylyltransferase 
                EC 2.7.7.54                      phenylalanine adenylyltransferase. The activity is part of EC 6.3.2.40, cyclopeptine synthase. 
                EC 2.7.7.55                      anthranilate adenylyltransferase. The activity is part of EC 6.3.2.40, cyclopeptine synthase. 
                EC 2.7.7.56                      tRNA nucleotidyltransferase 
                EC 2.7.7.57                      N-methylphosphoethanolamine cytidylyltransferase 
                EC 2.7.7.58                      (2,3-dihydroxybenzoyl)adenylate synthase. Now included in EC 6.2.1.71, 2,3-dihydroxybenzoate[aryl-carrier protein] ligase 
                EC 2.7.7.59                      [protein-PII] uridylyltransferase 
                EC 2.7.7.60                      2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
                EC 2.7.7.61                      citrate lyase holo-[acyl-carrier protein] synthase 
                EC 2.7.7.62                      adenosylcobinamide-phosphate guanylyltransferase 
                EC 2.7.7.63                      lipoate—protein ligase. Now EC 6.3.1.20, lipoate—protein ligase. 
                EC 2.7.7.64                      UTP-monosaccharide-1-phosphate uridylyltransferase 
                EC 2.7.7.65                      diguanylate cyclase 
                EC 2.7.7.66                      malonate decarboxylase holo-[acyl-carrier protein] synthase 
                EC 2.7.7.67                      CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase 
                EC 2.7.7.68                      2-phospho-L-lactate guanylyltransferase 
                EC 2.7.7.69                      GDP-L-galactose/GDP-D-glucose: hexose 1-phosphate guanylyltransferase 
                EC 2.7.7.70                      D-glycero-β-D-manno-heptose 1-phosphate adenylyltransferase 
                EC 2.7.7.71                      D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase 
                EC 2.7.7.72                      CCA tRNA nucleotidyltransferase 
                EC 2.7.7.73                      sulfur carrier protein ThiS adenylyltransferase 
                EC 2.7.7.74                      1L-myo-inositol 1-phosphate cytidylyltransferase 
                EC 2.7.7.75                      molybdopterin adenylyltransferase 
                EC 2.7.7.76                      molybdenum cofactor cytidylyltransferase 
                EC 2.7.7.77                      molybdenum cofactor guanylyltransferase 
                EC 2.7.7.78                      GDP-D-glucose phosphorylase 
                EC 2.7.7.79                      tRNAHis guanylyltransferase 
                EC 2.7.7.80                      molybdopterin-synthase adenylyltransferase 
                EC 2.7.7.81                      pseudaminic acid cytidylyltransferase 
                EC 2.7.7.82                      CMP-N,N′-diacetyllegionaminic acid synthase 
                EC 2.7.7.83                      UDP-N-acetylgalactosamine diphosphorylase 
                EC 2.7.7.84                      2′-5′ oligoadenylate synthase 
                EC 2.7.7.85                      diadenylate cyclase 
                EC 2.7.7.86                      cyclic GMP-AMP synthase 
                EC 2.7.7.87                      L-threonylcarbamoyladenylate synthase 
                EC 2.7.7.88                      GDP polyribonucleotidyltransferase 
                EC 2.7.7.89                      [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase 
                EC 2.7.7.90                      8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase 
                EC 2.7.7.91                      valienol-1-phosphate guanylyltransferase 
                EC 2.7.7.92                      3-deoxy-D-glycero-D-galacto-nonulopyranosonate cytidylyltransferase 
                EC 2.7.7.93                      phosphonoformate cytidylyltransferase 
                EC 2.7.7.94                      4-hydroxyphenylalkanoate adenylyltransferase. Now EC 6.2.1.51, 4-hydroxyphenylalkanoate adenylyltransferase FadD29 
                EC 2.7.7.95                      mycocerosic acid adenylyltransferase. Now EC 6.2.1.49, long-chain fatty acid adenylyltransferase FadD28 
                EC 2.7.7.96                      ADP-D-ribose pyrophosphorylase 
                EC 2.7.7.97                      3-hydroxy-4-methylanthranilate adenylyltransferase 
                EC 2.7.7.98                      4-hydroxybenzoate adenylyltransferase. Now EC 6.2.1.50, 4-hydroxybenzoate adenylyltransferase FadD22 
                EC 2.7.7.99                      N-acetyl-α-D-muramate 1-phosphate uridylyltransferase 
                EC 2.7.7.100                      SAMP-activating enzyme 
                EC 2.7.7.101                      DNA primase DnaG 
                EC 2.7.7.102                      DNA primase AEP 
                EC 2.7.7.103                      L-glutamine-phosphate cytidylyltransferase 
                EC 2.7.7.104                      2-hydroxyethylphosphonate cytidylyltransferase 
                EC 2.7.7.105                      phosphoenolpyruvate guanylyltransferase 
                EC 2.7.7.106                      3-phospho-D-glycerate guanylyltransferase 
                EC 2.7.7.107                      (2-aminoethyl)phosphonate cytidylyltransferase 
                EC 2.7.7.108                      protein adenylyltransferase 
        EC 2.7.8       []    Transferases for other substituted phosphate groups 
                EC 2.7.8.1                      ethanolaminephosphotransferase 
                EC 2.7.8.2                      diacylglycerol cholinephosphotransferase 
                EC 2.7.8.3                      ceramide cholinephosphotransferase 
                EC 2.7.8.4                      serine-phosphoethanolamine synthase 
                EC 2.7.8.5                      CDP-diacylglycerol—glycerol-3-phosphate 1-phosphatidyltransferase 
                EC 2.7.8.6                      undecaprenyl-phosphate galactose phosphotransferase 
                EC 2.7.8.7                      holo-[acyl-carrier-protein] synthase 
                EC 2.7.8.8                      CDP-diacylglycerol—serine O-phosphatidyltransferase 
                EC 2.7.8.9                      phosphomannan mannosephosphotransferase 
                EC 2.7.8.10                      sphingosine cholinephosphotransferase 
                EC 2.7.8.11                      CDP-diacylglycerol—inositol 3-phosphatidyltransferase 
                EC 2.7.8.12                      teichoic acid poly(glycerol phosphate) polymerase 
                EC 2.7.8.13                      phospho-N-acetylmuramoyl-pentapeptide-transferase 
                EC 2.7.8.14                      CDP-ribitol ribitolphosphotransferase 
                EC 2.7.8.15                      UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase 
                EC 2.7.8.16                       1-alkyl-2-acetylglycerol choline phosphotransferase. Now included with EC 2.7.8.2 diacylglycerol cholinephosphotransferase 
                EC 2.7.8.17                      UDP-N-acetylglucosamine—lysosomal-enzyme N-acetylglucosaminephosphotransferase 
                EC 2.7.8.18                      UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase 
                EC 2.7.8.19                      UDP-glucose—glycoprotein glucose phosphotransferase 
                EC 2.7.8.20                      phosphatidylglycerol—membrane-oligosaccharide glycerophosphotransferase 
                EC 2.7.8.21                      membrane-oligosaccharide glycerophosphotransferase 
                EC 2.7.8.22                      1-alkenyl-2-acylglycerol choline phosphotransferase 
                EC 2.7.8.23                      carboxyvinyl-carboxyphosphonate phosphorylmutase 
                EC 2.7.8.24                      phosphatidylcholine synthase 
                EC 2.7.8.25                      triphosphoribosyl-dephospho-CoA synthase. Now EC 2.4.2.52, triphosphoribosyl-dephospho-CoA synthase 
                EC 2.7.8.26                      adenosylcobinamide-GDP ribazoletransferase 
                EC 2.7.8.27                      sphingomyelin synthase 
                EC 2.7.8.28                      2-phospho-L-lactate transferase 
                EC 2.7.8.29                      L-serine-phosphatidylethanolamine phosphatidyltransferase 
                EC 2.7.8.30                      undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase. Now EC 2.4.2.53, undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase 
                EC 2.7.8.31                      undecaprenyl-phosphate glucose phosphotransferase 
                EC 2.7.8.32                      3-O-α-D-mannopyranosyl-α-D-mannopyranose xylosylphosphotransferase 
                EC 2.7.8.33                      UDP-N-acetylglucosamine—undecaprenyl-phosphate N-acetylglucosaminephosphotransferase 
                EC 2.7.8.34                      CDP-L-myo-inositol myo-inositolphosphotransferase 
                EC 2.7.8.35                      UDP-N-acetylglucosamine—decaprenyl-phosphate N-acetylglucosaminephosphotransferase 
                EC 2.7.8.36                      undecaprenyl phosphate N,N′-diacetylbacillosamine 1-phosphate transferase 
                EC 2.7.8.37                      α-D-ribose 1-methylphosphonate 5-triphosphate synthase 
                EC 2.7.8.38                      archaetidylserine synthase 
                EC 2.7.8.39                      archaetidylinositol phosphate synthase 
                EC 2.7.8.40                      UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase 
                EC 2.7.8.41                      cardiolipin synthase (CMP-forming)  
                EC 2.7.8.42                      Kdo2-lipid A phosphoethanolamine 7′′-transferase 
                EC 2.7.8.43                      lipid A phosphoethanolamine transferase 
                EC 2.7.8.44                      teichoic acid glycerol-phosphate primase 
                EC 2.7.8.45                      teichoic acid glycerol-phosphate transferase 
                EC 2.7.8.46                      teichoic acid ribitol-phosphate primase 
                EC 2.7.8.47                      teichoic acid ribitol-phosphate polymerase 
                EC 2.7.8.48                      ceramide phosphoethanolamine synthase 
        EC 2.7.9       []    Phosphotransferases with paired acceptors 
                EC 2.7.9.1                      pyruvate, phosphate dikinase 
                EC 2.7.9.2                      pyruvate, water dikinase 
                EC 2.7.9.3                      selenide, water dikinase 
                EC 2.7.9.4                      α-glucan, water dikinase 
                EC 2.7.9.5                      phosphoglucan, water dikinase 
                EC 2.7.9.6                      rifampicin phosphotransferase 
        EC 2.7.10       []    Protein-tyrosine kinases 
                EC 2.7.10.1                      receptor protein-tyrosine kinase 
                EC 2.7.10.2                      non-specific protein-tyrosine kinase 
                EC 2.7.10.3                      bacterial tyrosine kinase 
        EC 2.7.11       []    Protein-serine/threonine kinases 
                EC 2.7.11.1                      non-specific serine/threonine protein kinase 
                EC 2.7.11.2                      [pyruvate dehydrogenase (acetyl-transferring)] kinase 
                EC 2.7.11.3                      dephospho-[reductase kinase] kinase 
                EC 2.7.11.4                      [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase 
                EC 2.7.11.5                      [isocitrate dehydrogenase (NADP+)] kinase 
                EC 2.7.11.6                      [tyrosine 3-monooxygenase] kinase 
                EC 2.7.11.7                      myosin-heavy-chain kinase 
                EC 2.7.11.8                      Fas-activated serine/threonine kinase 
                EC 2.7.11.9                      Goodpasture-antigen-binding protein kinase 
                EC 2.7.11.10                      IκB kinase 
                EC 2.7.11.11                      cAMP-dependent protein kinase 
                EC 2.7.11.12                      cGMP-dependent protein kinase 
                EC 2.7.11.13                      protein kinase C 
                EC 2.7.11.14                      rhodopsin kinase 
                EC 2.7.11.15                      β-adrenergic-receptor kinase 
                EC 2.7.11.16                      G-protein-coupled receptor kinase 
                EC 2.7.11.17                      Ca2+/calmodulin-dependent protein kinase 
                EC 2.7.11.18                      myosin-light-chain kinase 
                EC 2.7.11.19                      phosphorylase kinase 
                EC 2.7.11.20                      elongation factor 2 kinase 
                EC 2.7.11.21                      polo kinase 
                EC 2.7.11.22                      cyclin-dependent kinase 
                EC 2.7.11.23                      [RNA-polymerase]-subunit kinase 
                EC 2.7.11.24                      mitogen-activated protein kinase 
                EC 2.7.11.25                      mitogen-activated protein kinase kinase kinase 
                EC 2.7.11.26                      tau-protein kinase 
                EC 2.7.11.27                      [acetyl-CoA carboxylase] kinase. Now classified under EC 2.7.11.31, 5-AMP-activated protein kinase. 
                EC 2.7.11.28                      tropomyosin kinase 
                EC 2.7.11.29                      low-density-lipoprotein receptor kinase 
                EC 2.7.11.30                      receptor protein serine/threonine kinase 
                EC 2.7.11.31                      [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase 
                EC 2.7.11.32                      [pyruvate, phosphate dikinase] kinase 
                EC 2.7.11.33                      [pyruvate, water dikinase] kinase 
                EC 2.7.11.34                      NEK6-subfamily protein kinase 
                EC 2.7.11.35                      CRIK-subfamily protein kinase 
        EC 2.7.12       []    Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) 
                EC 2.7.12.1                      dual-specificity kinase 
                EC 2.7.12.2                      mitogen-activated protein kinase kinase 
        EC 2.7.13       []    Protein-histidine kinases 
                EC 2.7.13.1                      protein-histidine pros-kinase 
                EC 2.7.13.2                      protein-histidine tele-kinase 
                EC 2.7.13.3                      histidine kinase 
        EC 2.7.14       []    Protein-arginine kinases 
                EC 2.7.14.1                      protein arginine kinase 
        EC 2.7.99       []    Other protein kinases 
                EC 2.7.99.1                      triphosphate—protein phosphotransferase 
    EC 2.8  [+]      
        EC 2.8.1       []    Sulfurtransferases 
                EC 2.8.1.1                      thiosulfate sulfurtransferase 
                EC 2.8.1.2                      3-mercaptopyruvate sulfurtransferase 
                EC 2.8.1.3                      thiosulfate—thiol sulfurtransferase 
                EC 2.8.1.4                      tRNA uracil 4-sulfurtransferase 
                EC 2.8.1.5                      thiosulfate—dithiol sulfurtransferase 
                EC 2.8.1.6                      biotin synthase 
                EC 2.8.1.7                      cysteine desulfurase 
                EC 2.8.1.8                      lipoyl synthase 
                EC 2.8.1.9                      molybdenum cofactor sulfurtransferase 
                EC 2.8.1.10                      thiazole synthase 
                EC 2.8.1.11                      molybdopterin synthase sulfurtransferase 
                EC 2.8.1.12                      molybdopterin synthase 
                EC 2.8.1.13                      tRNA-uridine 2-sulfurtransferase 
                EC 2.8.1.14                      tRNA-5-taurinomethyluridine 2-sulfurtransferase 
                EC 2.8.1.15                      tRNA-5-methyluridine54 2-sulfurtransferase 
                EC 2.8.1.16                      L-aspartate semialdehyde sulfurtransferase 
        EC 2.8.2       []    Sulfotransferases 
                EC 2.8.2.1                      aryl sulfotransferase 
                EC 2.8.2.2                      alcohol sulfotransferase 
                EC 2.8.2.3                      amine sulfotransferase 
                EC 2.8.2.4                      estrone sulfotransferase 
                EC 2.8.2.5                      chondroitin 4-sulfotransferase 
                EC 2.8.2.6                      choline sulfotransferase 
                EC 2.8.2.7                      UDP-N-acetylgalactosamine-4-sulfate sulfotransferase 
                EC 2.8.2.8                      [heparan sulfate]-glucosamine N-sulfotransferase 
                EC 2.8.2.9                      tyrosine-ester sulfotransferase 
                EC 2.8.2.10                      Renilla-luciferin sulfotransferase 
                EC 2.8.2.11                      galactosylceramide sulfotransferase 
                EC 2.8.2.12                       heparitin sulfotransferase. Enzyme identical to EC 2.8.2.8, [heparan sulfate]-glucosamine N-sulfotransferase 
                EC 2.8.2.13                      psychosine sulfotransferase 
                EC 2.8.2.14                      bile-salt sulfotransferase 
                EC 2.8.2.15                      steroid sulfotransferase 
                EC 2.8.2.16                      thiol sulfotransferase 
                EC 2.8.2.17                      chondroitin 6-sulfotransferase 
                EC 2.8.2.18                      cortisol sulfotransferase 
                EC 2.8.2.19                      triglucosylalkylacylglycerol sulfotransferase 
                EC 2.8.2.20                      protein-tyrosine sulfotransferase 
                EC 2.8.2.21                      keratan sulfotransferase 
                EC 2.8.2.22                      aryl-sulfate sulfotransferase 
                EC 2.8.2.23                      [heparan sulfate]-glucosamine 3-sulfotransferase 1 
                EC 2.8.2.24                      aromatic desulfoglucosinolate sulfotransferase 
                EC 2.8.2.25                      flavonol 3-sulfotransferase 
                EC 2.8.2.26                      quercetin-3-sulfate 3′-sulfotransferase 
                EC 2.8.2.27                      quercetin-3-sulfate 4′-sulfotransferase 
                EC 2.8.2.28                      quercetin-3,3′-bissulfate 7-sulfotransferase 
                EC 2.8.2.29                      [heparan sulfate]-glucosamine 3-sulfotransferase 2 
                EC 2.8.2.30                      [heparan sulfate]-glucosamine 3-sulfotransferase 3 
                EC 2.8.2.31                      petromyzonol sulfotransferase 
                EC 2.8.2.32                      scymnol sulfotransferase 
                EC 2.8.2.33                      N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase 
                EC 2.8.2.34                      glycochenodeoxycholate sulfotransferase 
                EC 2.8.2.35                      dermatan 4-sulfotransferase 
                EC 2.8.2.36                      desulfo-A47934 sulfotransferase 
                EC 2.8.2.37                      trehalose 2-sulfotransferase 
                EC 2.8.2.38                      aliphatic desulfoglucosinolate sulfotransferase 
                EC 2.8.2.39                      hydroxyjasmonate sulfotransferase 
                EC 2.8.2.40                      ω-hydroxy-β-dihydromenaquinone-9 sulfotransferase 
        EC 2.8.3       []    CoA-transferases 
                EC 2.8.3.1                      propionate CoA-transferase 
                EC 2.8.3.2                      oxalate CoA-transferase 
                EC 2.8.3.3                      malonate CoA-transferase 
                EC 2.8.3.4                       butyrate CoA-transferase 
                EC 2.8.3.5                      3-oxoacid CoA-transferase 
                EC 2.8.3.6                      3-oxoadipate CoA-transferase 
                EC 2.8.3.7                      succinate—citramalate CoA-transferase. The activity has now been shown to be due to two separate enzymes described by EC 2.8.3.22, succinyl-CoA—L-malate CoA-transferase, and EC 2.8.3.20, succinyl-CoA—D-citramalate CoA-transferase 
                EC 2.8.3.8                      acetate CoA-transferase 
                EC 2.8.3.9                      butyrate—acetoacetate CoA-transferase 
                EC 2.8.3.10                      citrate CoA-transferase 
                EC 2.8.3.11                      citramalate CoA-transferase 
                EC 2.8.3.12                      glutaconate CoA-transferase 
                EC 2.8.3.13                      succinate—hydroxymethylglutarate CoA-transferase 
                EC 2.8.3.14                      5-hydroxypentanoate CoA-transferase 
                EC 2.8.3.15                      succinyl-CoA:(R)-benzylsuccinate CoA-transferase 
                EC 2.8.3.16                      formyl-CoA transferase 
                EC 2.8.3.17                      3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase 
                EC 2.8.3.18                      succinyl-CoA:acetate CoA-transferase 
                EC 2.8.3.19                      CoA:oxalate CoA-transferase 
                EC 2.8.3.20                      succinyl-CoA—D-citramalate CoA-transferase 
                EC 2.8.3.21                      L-carnitine CoA-transferase 
                EC 2.8.3.22                      succinyl-CoA—L-malate CoA-transferase 
                EC 2.8.3.23                      caffeate CoA-transferase 
                EC 2.8.3.24                      (R)-2-hydroxy-4-methylpentanoate CoA-transferase 
                EC 2.8.3.25                      bile acid CoA-transferase 
                EC 2.8.3.26                      succinyl-CoA:mesaconate CoA transferase 
                EC 2.8.3.27                      propanoyl-CoA:succinate CoA transferase 
                EC 2.8.3.28                      phenylsuccinyl-CoA transferase 
        EC 2.8.4       []    Transferring alkylthio groups 
                EC 2.8.4.1                      coenzyme-B sulfoethylthiotransferase 
                EC 2.8.4.2                      arsenate-mycothiol transferase 
                EC 2.8.4.3                      tRNA-2-methylthio-N6-dimethylallyladenosine synthase 
                EC 2.8.4.4                      [ribosomal protein uS12] (aspartate89-C3)-methylthiotransferase 
                EC 2.8.4.5                      tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase 
                EC 2.8.4.6                      S-methyl-1-thioxylulose 5-phosphate methylthiotransferase 
        EC 2.8.5       []    Thiosulfotransferases 
                EC 2.8.5.1                      S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent) 
                EC 2.8.5.2                      L-cysteine S-thiosulfotransferase 
    EC 2.9  [+]      
        EC 2.9.1       []    Selenotransferases 
                EC 2.9.1.1                      L-seryl-tRNASec selenium transferase 
                EC 2.9.1.2                      O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase 
                EC 2.9.1.3                      tRNA 2-selenouridine synthase 
    EC 2.10  [+]      
        EC 2.10.1       []    Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors 
                EC 2.10.1.1                      molybdopterin molybdotransferase 
EC 3 [+]   
    EC 3.1  [+]      
        EC 3.1.1       []    Carboxylic-ester hydrolases 
                EC 3.1.1.1                      carboxylesterase 
                EC 3.1.1.2                      arylesterase 
                EC 3.1.1.3                      triacylglycerol lipase 
                EC 3.1.1.4                      phospholipase A2 
                EC 3.1.1.5                      lysophospholipase 
                EC 3.1.1.6                      acetylesterase 
                EC 3.1.1.7                      acetylcholinesterase 
                EC 3.1.1.8                      cholinesterase 
                EC 3.1.1.9                       benzoylcholinesterase; a side reaction of EC 3.1.1.8 cholinesterase 
                EC 3.1.1.10                      tropinesterase 
                EC 3.1.1.11                      pectinesterase 
                EC 3.1.1.12                       vitamin A esterase, now believed to be identical with EC 3.1.1.1 carboxylesterase 
                EC 3.1.1.13                      sterol esterase 
                EC 3.1.1.14                      chlorophyllase 
                EC 3.1.1.15                      L-arabinonolactonase 
                EC 3.1.1.16                       4-carboxymethyl-4-hydroxyisocrotonolactonase. This reaction was due to a mixture of EC 5.3.3.4 (muconolactone Δ-isomerase) and EC 3.1.1.24 (3-oxoadipate enol-lactonase) 
                EC 3.1.1.17                      gluconolactonase 
                EC 3.1.1.18                       aldonolactonase. Now included with EC 3.1.1.17 gluconolactonase 
                EC 3.1.1.19                      uronolactonase 
                EC 3.1.1.20                      tannase 
                EC 3.1.1.21                      retinyl-palmitate esterase. Now known to be catalysed by EC 3.1.1.1, carboxylesterase and EC 3.1.1.3, triacylglycerol lipase. 
                EC 3.1.1.22                      hydroxybutyrate-dimer hydrolase 
                EC 3.1.1.23                      acylglycerol lipase 
                EC 3.1.1.24                      3-oxoadipate enol-lactonase 
                EC 3.1.1.25                      1,4-lactonase 
                EC 3.1.1.26                      galactolipase 
                EC 3.1.1.27                      4-pyridoxolactonase 
                EC 3.1.1.28                      acylcarnitine hydrolase 
                EC 3.1.1.29                      peptidyl-tRNA hydrolase 
                EC 3.1.1.30                      D-arabinonolactonase 
                EC 3.1.1.31                      6-phosphogluconolactonase 
                EC 3.1.1.32                      phospholipase A1 
                EC 3.1.1.33                      6-acetylglucose deacetylase 
                EC 3.1.1.34                      lipoprotein lipase 
                EC 3.1.1.35                      dihydrocoumarin hydrolase 
                EC 3.1.1.36                      limonin-D-ring-lactonase 
                EC 3.1.1.37                      steroid-lactonase 
                EC 3.1.1.38                      triacetate-lactonase 
                EC 3.1.1.39                      actinomycin lactonase 
                EC 3.1.1.40                      orsellinate-depside hydrolase 
                EC 3.1.1.41                      cephalosporin-C deacetylase 
                EC 3.1.1.42                      chlorogenate hydrolase 
                EC 3.1.1.43                      α-amino-acid esterase 
                EC 3.1.1.44                      4-methyloxaloacetate esterase 
                EC 3.1.1.45                      carboxymethylenebutenolidase 
                EC 3.1.1.46                      deoxylimonate A-ring-lactonase 
                EC 3.1.1.47                      1-alkyl-2-acetylglycerophosphocholine esterase 
                EC 3.1.1.48                      fusarinine-C ornithinesterase 
                EC 3.1.1.49                      sinapine esterase 
                EC 3.1.1.50                      wax-ester hydrolase 
                EC 3.1.1.51                      phorbol-diester hydrolase 
                EC 3.1.1.52                      phosphatidylinositol deacylase 
                EC 3.1.1.53                      sialate O-acetylesterase 
                EC 3.1.1.54                      acetoxybutynylbithiophene deacetylase 
                EC 3.1.1.55                      acetylsalicylate deacetylase 
                EC 3.1.1.56                      methylumbelliferyl-acetate deacetylase 
                EC 3.1.1.57                      2-pyrone-4,6-dicarboxylate lactonase 
                EC 3.1.1.58                      N-acetylgalactosaminoglycan deacetylase 
                EC 3.1.1.59                      juvenile-hormone esterase 
                EC 3.1.1.60                      bis(2-ethylhexyl)phthalate esterase 
                EC 3.1.1.61                      protein-glutamate methylesterase 
                EC 3.1.1.62                      N-acetyldiaminopimelate deacylase. Now listed as EC 3.5.1.47, N-acetyldiaminopimelate deacetylase 
                EC 3.1.1.63                      11-cis-retinyl-palmitate hydrolase 
                EC 3.1.1.64                      retinoid isomerohydrolase 
                EC 3.1.1.65                      L-rhamnono-1,4-lactonase 
                EC 3.1.1.66                      5-(3,4-diacetoxybut-1-ynyl)-2,2′-bithiophene deacetylase 
                EC 3.1.1.67                      fatty-acyl-ethyl-ester synthase 
                EC 3.1.1.68                      xylono-1,4-lactonase 
                EC 3.1.1.69                      N-acetylglucosaminylphosphatidylinositol deacetylase. Now EC 3.5.1.89, N-acetylglucosaminylphosphatidylinositol deacetylase. Previously classified erroneously as an enzyme that hydrolysed an ester and not an amide 
                EC 3.1.1.70                      cetraxate benzylesterase 
                EC 3.1.1.71                      acetylalkylglycerol acetylhydrolase 
                EC 3.1.1.72                      acetylxylan esterase 
                EC 3.1.1.73                      feruloyl esterase 
                EC 3.1.1.74                      cutinase 
                EC 3.1.1.75                      poly(3-hydroxybutyrate) depolymerase 
                EC 3.1.1.76                      poly(3-hydroxyoctanoate) depolymerase 
                EC 3.1.1.77                      acyloxyacyl hydrolase 
                EC 3.1.1.78                      polyneuridine-aldehyde esterase 
                EC 3.1.1.79                      hormone-sensitive lipase 
                EC 3.1.1.80                      acetylajmaline esterase 
                EC 3.1.1.81                      quorum-quenching N-acyl-homoserine lactonase 
                EC 3.1.1.82                      pheophorbidase 
                EC 3.1.1.83                      monoterpene ε-lactone hydrolase 
                EC 3.1.1.84                      cocaine esterase 
                EC 3.1.1.85                      pimelyl-[acyl-carrier protein] methyl ester esterase 
                EC 3.1.1.86                      rhamnogalacturonan acetylesterase 
                EC 3.1.1.87                      fumonisin B1 esterase 
                EC 3.1.1.88                      pyrethroid hydrolase 
                EC 3.1.1.89                      protein phosphatase methylesterase-1 
                EC 3.1.1.90                      all-trans-retinyl ester 13-cis isomerohydrolase 
                EC 3.1.1.91                      2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase 
                EC 3.1.1.92                      4-sulfomuconolactone hydrolase 
                EC 3.1.1.93                      mycophenolic acid acyl-glucuronide esterase 
                EC 3.1.1.94                      versiconal hemiacetal acetate esterase 
                EC 3.1.1.95                      aclacinomycin methylesterase 
                EC 3.1.1.96                      D-aminoacyl-tRNA deacylase 
                EC 3.1.1.97                      methylated diphthine methylhydrolase 
                EC 3.1.1.98                      [Wnt protein] O-palmitoleoyl-L-serine hydrolase 
                EC 3.1.1.99                      6-deoxy-6-sulfogluconolactonase 
                EC 3.1.1.100                      chlorophyllide a hydrolase 
                EC 3.1.1.101                      poly(ethylene terephthalate) hydrolase 
                EC 3.1.1.102                      mono(ethylene terephthalate) hydrolase 
                EC 3.1.1.103                      teichoic acid D-alanine hydrolase 
                EC 3.1.1.104                      5-phospho-D-xylono-1,4-lactonase 
                EC 3.1.1.105                      3-O-acetylpapaveroxine carboxylesterase 
                EC 3.1.1.106                      O-acetyl-ADP-ribose deacetylase 
                EC 3.1.1.107                      apo-salmochelin esterase 
                EC 3.1.1.108                      iron(III)-enterobactin esterase 
                EC 3.1.1.109                      iron(III)-salmochelin esterase 
                EC 3.1.1.110                      xylono-1,5-lactonase 
                EC 3.1.1.111                      phosphatidylserine sn-1 acylhydrolase 
                EC 3.1.1.112                      isoamyl acetate esterase 
                EC 3.1.1.113                      ethyl acetate hydrolase 
                EC 3.1.1.114                      methyl acetate hydrolase 
                EC 3.1.1.115                      D-apionolactonase 
                EC 3.1.1.116                      sn-1-specific diacylglycerol lipase 
                EC 3.1.1.117                      (4-O-methyl)-D-glucuronate—lignin esterase 
                EC 3.1.1.118                      phospholipid sn-1 acylhydrolase 
                EC 3.1.1.119                      exo-acting protein-α-N-acetylgalactosaminidase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 3.2.1.217, exo-acting protein-α-N-acetylgalactosaminidase. 
                EC 3.1.1.120                      L-fucono-1,5-lactonase 
                EC 3.1.1.121                      ergosteryl-3β-O-L-aspartate hydrolase 
                EC 3.1.1.122                      carbendazim hydrolysing esterase 
        EC 3.1.2       []    Thioester hydrolases 
                EC 3.1.2.1                      acetyl-CoA hydrolase 
                EC 3.1.2.2                      palmitoyl-CoA hydrolase 
                EC 3.1.2.3                      succinyl-CoA hydrolase 
                EC 3.1.2.4                      3-hydroxyisobutyryl-CoA hydrolase 
                EC 3.1.2.5                      hydroxymethylglutaryl-CoA hydrolase 
                EC 3.1.2.6                      hydroxyacylglutathione hydrolase 
                EC 3.1.2.7                      glutathione thiolesterase 
                EC 3.1.2.8                       S-acetoacylglutathione hydrolase. Now included with EC 3.1.2.6 hydroxyacylglutathione hydrolase 
                EC 3.1.2.9                       S-acetoacetylhydrolipoate hydrolase 
                EC 3.1.2.10                      formyl-CoA hydrolase 
                EC 3.1.2.11                      acetoacetyl-CoA hydrolase 
                EC 3.1.2.12                      S-formylglutathione hydrolase 
                EC 3.1.2.13                      S-succinylglutathione hydrolase 
                EC 3.1.2.14                      oleoyl-[acyl-carrier-protein] hydrolase 
                EC 3.1.2.15                      This activity is covered by EC 3.4.19.12, ubiquitinyl hydrolase 1 
                EC 3.1.2.16                      citrate-lyase deacetylase 
                EC 3.1.2.17                      (S)-methylmalonyl-CoA hydrolase 
                EC 3.1.2.18                      ADP-dependent short-chain-acyl-CoA hydrolase 
                EC 3.1.2.19                      ADP-dependent medium-chain-acyl-CoA hydrolase 
                EC 3.1.2.20                      acyl-CoA hydrolase 
                EC 3.1.2.21                      dodecanoyl-[acyl-carrier-protein] hydrolase 
                EC 3.1.2.22                      palmitoyl[protein] hydrolase 
                EC 3.1.2.23                      4-hydroxybenzoyl-CoA thioesterase 
                EC 3.1.2.24                      2-(2-hydroxyphenyl)benzenesulfinate hydrolase. Now EC 3.13.1.3, 2′-hydroxybiphenyl-2-sulfinate desulfinase. The enzyme was incorrectly classified as a thioester hydrolase when the bond broken is a C-S bond, which is not an ester 
                EC 3.1.2.25                      phenylacetyl-CoA hydrolase 
                EC 3.1.2.26                      bile-acid-CoA hydrolase. Now EC 2.8.3.25, bile acid CoA transferase 
                EC 3.1.2.27                      choloyl-CoA hydrolase 
                EC 3.1.2.28                      1,4-dihydroxy-2-naphthoyl-CoA hydrolase 
                EC 3.1.2.29                      fluoroacetyl-CoA thioesterase 
                EC 3.1.2.30                      (3S)-malyl-CoA thioesterase  
                EC 3.1.2.31                      dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase 
                EC 3.1.2.32                      2-aminobenzoylacetyl-CoA thioesterase 
        EC 3.1.3       []    Phosphoric-monoester hydrolases 
                EC 3.1.3.1                      alkaline phosphatase 
                EC 3.1.3.2                      acid phosphatase 
                EC 3.1.3.3                      phosphoserine phosphatase 
                EC 3.1.3.4                      phosphatidate phosphatase 
                EC 3.1.3.5                      5′-nucleotidase 
                EC 3.1.3.6                      3′-nucleotidase 
                EC 3.1.3.7                      3′(2′),5′-bisphosphate nucleotidase 
                EC 3.1.3.8                      3-phytase 
                EC 3.1.3.9                      glucose-6-phosphatase 
                EC 3.1.3.10                      glucose-1-phosphatase 
                EC 3.1.3.11                      fructose-bisphosphatase 
                EC 3.1.3.12                      trehalose-phosphatase 
                EC 3.1.3.13                      bisphosphoglycerate phosphatase. Recent studies have shown that this is a partial activity of EC 5.4.2.11, phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) 
                EC 3.1.3.14                      methylphosphothioglycerate phosphatase 
                EC 3.1.3.15                      histidinol-phosphatase 
                EC 3.1.3.16                      protein-serine/threonine phosphatase 
                EC 3.1.3.17                      [phosphorylase] phosphatase 
                EC 3.1.3.18                      phosphoglycolate phosphatase 
                EC 3.1.3.19                      glycerol-2-phosphatase 
                EC 3.1.3.20                      phosphoglycerate phosphatase 
                EC 3.1.3.21                      glycerol-1-phosphatase 
                EC 3.1.3.22                      mannitol-1-phosphatase 
                EC 3.1.3.23                      sugar-phosphatase 
                EC 3.1.3.24                      sucrose-phosphate phosphatase 
                EC 3.1.3.25                      inositol-phosphate phosphatase 
                EC 3.1.3.26                      4-phytase 
                EC 3.1.3.27                      phosphatidylglycerophosphatase 
                EC 3.1.3.28                      ADP-phosphoglycerate phosphatase 
                EC 3.1.3.29                      N-acylneuraminate-9-phosphatase 
                EC 3.1.3.30                       3′-phosphoadenylylsulfate 3′-phosphatase. The activity may be that of an acid phosphatase. 
                EC 3.1.3.31                      nucleotidase. The activity may be that of an acid phosphatase. 
                EC 3.1.3.32                      polynucleotide 3′-phosphatase 
                EC 3.1.3.33                      polynucleotide 5′-phosphatase 
                EC 3.1.3.34                      deoxynucleotide 3′-phosphatase 
                EC 3.1.3.35                      thymidylate 5′-phosphatase 
                EC 3.1.3.36                      phosphoinositide 5-phosphatase 
                EC 3.1.3.37                      sedoheptulose-bisphosphatase 
                EC 3.1.3.38                      3-phosphoglycerate phosphatase 
                EC 3.1.3.39                      streptomycin-6-phosphatase 
                EC 3.1.3.40                      guanidinodeoxy-scyllo-inositol-4-phosphatase 
                EC 3.1.3.41                      4-nitrophenylphosphatase 
                EC 3.1.3.42                      [glycogen-synthase-D] phosphatase 
                EC 3.1.3.43                      [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase 
                EC 3.1.3.44                      [acetyl-CoA carboxylase]-phosphatase 
                EC 3.1.3.45                      3-deoxy-manno-octulosonate-8-phosphatase 
                EC 3.1.3.46                      fructose-2,6-bisphosphate 2-phosphatase 
                EC 3.1.3.47                      [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase 
                EC 3.1.3.48                      protein-tyrosine-phosphatase 
                EC 3.1.3.49                      [pyruvate kinase]-phosphatase 
                EC 3.1.3.50                      sorbitol-6-phosphatase 
                EC 3.1.3.51                      dolichyl-phosphatase 
                EC 3.1.3.52                      [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase 
                EC 3.1.3.53                      [myosin-light-chain] phosphatase 
                EC 3.1.3.54                      fructose-2,6-bisphosphate 6-phosphatase 
                EC 3.1.3.55                      caldesmon-phosphatase 
                EC 3.1.3.56                      inositol-polyphosphate 5-phosphatase 
                EC 3.1.3.57                      inositol-1,4-bisphosphate 1-phosphatase 
                EC 3.1.3.58                      sugar-terminal-phosphatase 
                EC 3.1.3.59                      alkylacetylglycerophosphatase 
                EC 3.1.3.60                      phosphoenolpyruvate phosphatase 
                EC 3.1.3.61                       inositol-1,4,5-trisphosphate 1-phosphatase, as its existence has not been established 
                EC 3.1.3.62                      multiple inositol-polyphosphate phosphatase 
                EC 3.1.3.63                      2-carboxy-D-arabinitol-1-phosphatase 
                EC 3.1.3.64                      phosphatidylinositol-3-phosphatase 
                EC 3.1.3.65                       inositol-1,3-bisphosphate 3-phosphatase. Now included with EC 3.1.3.64, phosphatidylinositol-3-phosphatase 
                EC 3.1.3.66                      phosphatidylinositol-3,4-bisphosphate 4-phosphatase 
                EC 3.1.3.67                      phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 
                EC 3.1.3.68                      2-deoxyglucose-6-phosphatase 
                EC 3.1.3.69                      glucosylglycerol 3-phosphatase 
                EC 3.1.3.70                      mannosyl-3-phosphoglycerate phosphatase 
                EC 3.1.3.71                      2-phosphosulfolactate phosphatase 
                EC 3.1.3.72                      5-phytase 
                EC 3.1.3.73                      adenosylcobalamin/α-ribazole phosphatase 
                EC 3.1.3.74                      pyridoxal phosphatase 
                EC 3.1.3.75                      phosphoethanolamine/phosphocholine phosphatase 
                EC 3.1.3.76                      lipid-phosphate phosphatase 
                EC 3.1.3.77                      acireductone synthase 
                EC 3.1.3.78                      phosphatidylinositol-4,5-bisphosphate 4-phosphatase 
                EC 3.1.3.79                      mannosylfructose-phosphate phosphatase 
                EC 3.1.3.80                      2,3-bisphosphoglycerate 3-phosphatase 
                EC 3.1.3.81                      diacylglycerol diphosphate phosphatase. Now EC 3.6.1.75, diacylglycerol diphosphate phosphatase 
                EC 3.1.3.82                      D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase 
                EC 3.1.3.83                      D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase 
                EC 3.1.3.84                      ADP-ribose 1′′-phosphate phosphatase 
                EC 3.1.3.85                      glucosyl-3-phosphoglycerate phosphatase 
                EC 3.1.3.86                      phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 
                EC 3.1.3.87                      2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 
                EC 3.1.3.88                      5′′-phosphoribostamycin phosphatase 
                EC 3.1.3.89                      5′-deoxynucleotidase 
                EC 3.1.3.90                      maltose 6′-phosphate phosphatase 
                EC 3.1.3.91                      7-methylguanosine nucleotidase 
                EC 3.1.3.92                      kanosamine-6-phosphate phosphatase 
                EC 3.1.3.93                      L-galactose 1-phosphate phosphatase 
                EC 3.1.3.94                      D-galactose 1-phosphate phosphatase 
                EC 3.1.3.95                      phosphatidylinositol-3,5-bisphosphate 3-phosphatase 
                EC 3.1.3.96                      pseudouridine 5′-phosphatase 
                EC 3.1.3.97                      3′,5′-nucleoside bisphosphate phosphatase 
                EC 3.1.3.98                      geranyl diphosphate phosphohydrolase, transferred to EC 3.6.1.68, geranyl diphosphate phosphohydrolase 
                EC 3.1.3.99                      IMP-specific 5′-nucleotidase 
                EC 3.1.3.100                      thiamine phosphate phosphatase 
                EC 3.1.3.101                      validoxylamine A 7′-phosphate phosphatase 
                EC 3.1.3.102                      FMN hydrolase 
                EC 3.1.3.103                      3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase 
                EC 3.1.3.104                      5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase 
                EC 3.1.3.105                      N-acetyl-D-muramate 6-phosphate phosphatase 
                EC 3.1.3.106                      2-lysophosphatidate phosphatase 
                EC 3.1.3.107                      amicoumacin phosphatase 
                EC 3.1.3.108                      nocturnin 
                EC 3.1.3.109                      ribulose-1,5-bisphosphate 5-phosphatase 
        EC 3.1.4       []    Phosphoric-diester hydrolases 
                EC 3.1.4.1                      phosphodiesterase I 
                EC 3.1.4.2                      glycerophosphocholine phosphodiesterase 
                EC 3.1.4.3                      phospholipase C 
                EC 3.1.4.4                      phospholipase D 
                EC 3.1.4.5                      deoxyribonuclease. Now EC 3.1.21.1, deoxyribonuclease I 
                EC 3.1.4.6                      deoxyribonuclease II. Now EC 3.1.22.1, deoxyribonuclease II 
                EC 3.1.4.7                      micrococcal nuclease. Now EC 3.1.31.1, micrococcal nuclease 
                EC 3.1.4.8                      Aspergillus oryzae ribonuclease. Now EC 3.1.27.3, ribonuclease T1 
                EC 3.1.4.9                      nucleate endonuclease. Now EC 3.1.30.2, Serratia marcescens nuclease 
                EC 3.1.4.10                      1-phosphatidylinositol phosphodiesterase. Now EC 4.6.1.13, phosphatidylinositol diacylglycerol-lyase. As there is no hydrolysis of the inositol 1,2-cyclic phosphate formed, previous classification of the enzyme as a hydrolase was incorrect 
                EC 3.1.4.11                      phosphoinositide phospholipase C 
                EC 3.1.4.12                      sphingomyelin phosphodiesterase 
                EC 3.1.4.13                      serine-ethanolaminephosphate phosphodiesterase 
                EC 3.1.4.14                      [acyl-carrier-protein] phosphodiesterase 
                EC 3.1.4.15                      adenylyl-[glutamateammonia ligase] hydrolase. As it has been shown that the enzyme catalyses a transfer of the adenylyl group to phosphate, the enzyme has been transferred to EC 2.7.7.89, adenylyl-[glutamateammonia ligase] phosphorylase 
                EC 3.1.4.16                      2′,3′-cyclic-nucleotide 2′-phosphodiesterase 
                EC 3.1.4.17                      3′,5′-cyclic-nucleotide phosphodiesterase 
                EC 3.1.4.18                      phosphodiesterase II. Now EC 3.1.16.1, spleen exonuclease 
                EC 3.1.4.19                      oligonucleotidase. Now EC 3.1.13.3, oligonucleotidase 
                EC 3.1.4.20                      exoribonuclease. Now EC 3.1.13.1, exoribonuclease II 
                EC 3.1.4.21                      single-stranded-nucleate endonuclease. Now EC 3.1.30.1, Aspergillus nuclease S1 
                EC 3.1.4.22                      ribonuclease I. Now EC 3.1.27.5, pancreatic ribonuclease 
                EC 3.1.4.23                      ribonuclease II. Now EC 3.1.27.1, ribonuclease T2 
                EC 3.1.4.24                       endoribonuclease III 
                EC 3.1.4.25                      exodeoxyribonuclease I. Now EC 3.1.11.1, exodeoxyribonuclease I 
                EC 3.1.4.26                       exodeoxyribonuclease II 
                EC 3.1.4.27                      exodeoxyribonuclease III. Now EC 3.1.11.2, exodeoxyribonuclease III 
                EC 3.1.4.28                      exodeoxyribonuclease IV. Now EC 3.1.11.3, exodeoxyribonuclease (lambda-induced) 
                EC 3.1.4.29                       oligodeoxyribonucleate exonuclease 
                EC 3.1.4.30                      endodeoxyribonuclease. Now EC 3.1.21.2, deoxyribonuclease IV (phage-T4-induced) 
                EC 3.1.4.31                      DNA 5′-dinucleotidohydrolase. Now EC 3.1.11.4, exodeoxyribonuclease (phage SP3-induced) 
                EC 3.1.4.32                       endodeoxyribonuclease (ATP- and S-adenosylmethionine-dependent). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease 
                EC 3.1.4.33                       endodeoxyribonuclease (ATP-hydrolysing). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease 
                EC 3.1.4.34                       hybrid nuclease. See sub-subclasses EC 3.1.15, EC 3.1.16, EC 3.1.30 and EC 3.1.31. 
                EC 3.1.4.35                      3′,5′-cyclic-GMP phosphodiesterase 
                EC 3.1.4.36                       1,2-cyclic-inositol-phosphate phosphodiesterase. Now included with EC 3.1.4.43, glycerophosphoinositol inositolphosphodiesterase 
                EC 3.1.4.37                      2′,3′-cyclic-nucleotide 3′-phosphodiesterase 
                EC 3.1.4.38                      glycerophosphocholine cholinephosphodiesterase 
                EC 3.1.4.39                      alkylglycerophosphoethanolamine phosphodiesterase 
                EC 3.1.4.40                      CMP-N-acylneuraminate phosphodiesterase 
                EC 3.1.4.41                      sphingomyelin phosphodiesterase D 
                EC 3.1.4.42                      glycerol-1,2-cyclic-phosphate 2-phosphodiesterase 
                EC 3.1.4.43                      glycerophosphoinositol inositolphosphodiesterase 
                EC 3.1.4.44                      glycerophosphoinositol glycerophosphodiesterase 
                EC 3.1.4.45                      N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase 
                EC 3.1.4.46                      glycerophosphodiester phosphodiesterase 
                EC 3.1.4.47                      variant-surface-glycoprotein phospholipase C. Now EC 4.6.1.14, glycosylphosphatidylinositol diacylglycerol-lyase 
                EC 3.1.4.48                      dolichylphosphate-glucose phosphodiesterase 
                EC 3.1.4.49                      dolichylphosphate-mannose phosphodiesterase 
                EC 3.1.4.50                      glycosylphosphatidylinositol phospholipase D 
                EC 3.1.4.51                      glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase 
                EC 3.1.4.52                      cyclic-guanylate-specific phosphodiesterase 
                EC 3.1.4.53                      3′,5′-cyclic-AMP phosphodiesterase 
                EC 3.1.4.54                      N-acetylphosphatidylethanolamine-hydrolysing phospholipase D 
                EC 3.1.4.55                      phosphoribosyl 1,2-cyclic phosphate phosphodiesterase 
                EC 3.1.4.56                      7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase 
                EC 3.1.4.57                      phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase 
                EC 3.1.4.58                      RNA 2′,3′-cyclic 3′-phosphodiesterase 
                EC 3.1.4.59                      cyclic-di-AMP phosphodiesterase 
                EC 3.1.4.60                      pApA phosphodiesterase 
                EC 3.1.4.61                      cyclic 2,3-diphosphoglycerate hydrolase 
        EC 3.1.5       []    Triphosphoric-monoester hydrolases 
                EC 3.1.5.1                      dGTPase 
        EC 3.1.6       []    Sulfuric-ester hydrolases 
                EC 3.1.6.1                      arylsulfatase (type I) 
                EC 3.1.6.2                      steryl-sulfatase 
                EC 3.1.6.3                      glycosulfatase 
                EC 3.1.6.4                      N-acetylgalactosamine-6-sulfatase 
                EC 3.1.6.5                       sinigrin sulfohydrolase; myrosulfatase 
                EC 3.1.6.6                      choline-sulfatase 
                EC 3.1.6.7                      cellulose-polysulfatase 
                EC 3.1.6.8                      cerebroside-sulfatase 
                EC 3.1.6.9                      chondro-4-sulfatase 
                EC 3.1.6.10                      chondro-6-sulfatase 
                EC 3.1.6.11                      disulfoglucosamine-6-sulfatase 
                EC 3.1.6.12                      N-acetylgalactosamine-4-sulfatase 
                EC 3.1.6.13                      iduronate-2-sulfatase 
                EC 3.1.6.14                      N-acetylglucosamine-6-sulfatase 
                EC 3.1.6.15                      N-sulfoglucosamine-3-sulfatase 
                EC 3.1.6.16                      monomethyl-sulfatase 
                EC 3.1.6.17                      D-lactate-2-sulfatase 
                EC 3.1.6.18                      glucuronate-2-sulfatase 
                EC 3.1.6.19                      (R)-specific secondary-alkylsulfatase (type III) 
                EC 3.1.6.20                      S-sulfosulfanyl-L-cysteine sulfohydrolase 
                EC 3.1.6.21                      linear primary-alkylsulfatase 
                EC 3.1.6.22                      branched primary-alkylsulfatase 
        EC 3.1.7       []    Diphosphoric-monoester hydrolases 
                EC 3.1.7.1                      prenyl-diphosphatase 
                EC 3.1.7.2                      guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase 
                EC 3.1.7.3                      monoterpenyl-diphosphatase 
                EC 3.1.7.4                      Now recognized as two enzymes EC 4.2.1.133, copal-8-ol diphosphate synthase and EC 4.2.3.141 sclareol synthase 
                EC 3.1.7.5                      geranylgeranyl diphosphate diphosphatase 
                EC 3.1.7.6                      farnesyl diphosphatase 
                EC 3.1.7.7                      (–)-drimenol synthase. Now EC 4.2.3.194, (–)-drimenol synthase 
                EC 3.1.7.8                      tuberculosinol synthase. Now known to be partial activity of EC 2.5.1.153, adenosine tuberculosinyltransferase. 
                EC 3.1.7.9                      isotuberculosinol synthase. Now known to be partial activity of EC 2.5.1.153, adenosine tuberculosinyltransferase. 
                EC 3.1.7.10                      (13E)-labda-7,13-dien-15-ol synthase 
                EC 3.1.7.11                      geranyl diphosphate diphosphatase 
                EC 3.1.7.12                      (+)-kolavelool synthase 
                EC 3.1.7.13                      neryl diphosphate diphosphatase 
        EC 3.1.8       []    Phosphoric-triester hydrolases 
                EC 3.1.8.1                      aryldialkylphosphatase 
                EC 3.1.8.2                      diisopropyl-fluorophosphatase. Now classified as EC 3.8.2.2, diisopropyl-fluorophosphatase 
        EC 3.1.11       []    Exodeoxyribonucleases producing 5′-phosphomonoesters 
                EC 3.1.11.1                      exodeoxyribonuclease I 
                EC 3.1.11.2                      exodeoxyribonuclease III 
                EC 3.1.11.3                      exodeoxyribonuclease (lambda-induced) 
                EC 3.1.11.4                      exodeoxyribonuclease (phage SP3-induced) 
                EC 3.1.11.5                      exodeoxyribonuclease V 
                EC 3.1.11.6                      exodeoxyribonuclease VII 
                EC 3.1.11.7                      adenosine-5′-diphospho-5′-[DNA] diphosphatase. Now EC 3.6.1.71, adenosine-5′-diphospho-5′-[DNA] diphosphatase 
                EC 3.1.11.8                      guanosine-5′-diphospho-5′-[DNA] diphosphatase. Now EC 3.6.1.70, guanosine-5′-diphospho-5′-[DNA] diphosphatase 
        EC 3.1.12       []    Exodeoxyribonucleases producing 3′-phosphomonoesters 
                EC 3.1.12.1                      5′ to 3′ exodeoxyribonuclease (nucleoside 3′-phosphate-forming) 
                EC 3.1.12.2                      DNA-3-diphospho-5-guanosine diphosphatase. Now EC 3.6.1.72, DNA-3-diphospho-5-guanosine diphosphatase 
        EC 3.1.13       []    Exoribonucleases producing 5′-phosphomonoesters 
                EC 3.1.13.1                      exoribonuclease II 
                EC 3.1.13.2                      exoribonuclease H 
                EC 3.1.13.3                      oligonucleotidase 
                EC 3.1.13.4                      poly(A)-specific ribonuclease 
                EC 3.1.13.5                      ribonuclease D 
        EC 3.1.14       []    Exoribonucleases producing 3'-phosphomonoesters 
                EC 3.1.14.1                      yeast ribonuclease 
        EC 3.1.15       []    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
                EC 3.1.15.1                      venom exonuclease 
        EC 3.1.16       []    Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
                EC 3.1.16.1                      spleen exonuclease 
        EC 3.1.21       []    Endodeoxyribonucleases producing 5'-phosphomonoesters 
                EC 3.1.21.1                      deoxyribonuclease I 
                EC 3.1.21.2                      deoxyribonuclease IV 
                EC 3.1.21.3                      type I site-specific deoxyribonuclease 
                EC 3.1.21.4                      type II site-specific deoxyribonuclease 
                EC 3.1.21.5                      type III site-specific deoxyribonuclease 
                EC 3.1.21.6                      CC-preferring endodeoxyribonuclease 
                EC 3.1.21.7                      deoxyribonuclease V 
                EC 3.1.21.8                      T4 deoxyribonuclease II 
                EC 3.1.21.9                      T4 deoxyribonuclease IV 
                EC 3.1.21.10                      crossover junction endodeoxyribonuclease 
        EC 3.1.22       []    Endodeoxyribonucleases producing 3'-phosphomonoesters 
                EC 3.1.22.1                      deoxyribonuclease II 
                EC 3.1.22.2                      Aspergillus deoxyribonuclease K1 
                EC 3.1.22.3                      deoxyribonuclease V. Now EC 3.1.21.7, deoxyribonuclease V 
                EC 3.1.22.4                      crossover junction endodeoxyribonuclease. Now EC 3.1.21.10, crossover junction endodeoxyribonuclease 
                EC 3.1.22.5                      deoxyribonuclease X 
        EC 3.1.23       []    Site-specific endodeoxyribonucleases: cleavage is sequence specific (deleted sub-subclass) 
                EC 3.1.23.1                      endodeoxyribonuclease AluI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.2                      endodeoxyribonuclease AsuI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.3                      endodeoxyribonuclease AvaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.4                      endodeoxyribonuclease AvaII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.5                      endodeoxyribonuclease BalI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.6                      endodeoxyribonuclease BamHI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.7                      endodeoxyribonuclease BbvI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.8                      endodeoxyribonuclease BclI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.9                      endodeoxyribonuclease BglI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.10                      endodeoxyribonuclease BglII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.11                      endodeoxyribonuclease BpuI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.12                      endodeoxyribonuclease DpnI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.13                      endodeoxyribonuclease EcoRI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.14                      endodeoxyribonuclease EcoRII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.15                      endodeoxyribonuclease HaeI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.16                      endodeoxyribonuclease HaeII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.17                      endodeoxyribonuclease HaeIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.18                      endodeoxyribonuclease HgaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.19                      endodeoxyribonuclease HhaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.20                      endodeoxyribonuclease HindII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.21                      endodeoxyribonuclease HindIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.22                      endodeoxyribonuclease HinfI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.23                      endodeoxyribonuclease HpaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.24                      endodeoxyribonuclease HpaII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.25                      endodeoxyribonuclease HphI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.26                      endodeoxyribonuclease KpnI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.27                      endodeoxyribonuclease MboI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.28                      endodeoxyribonuclease MboII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.29                      endodeoxyribonuclease MnlI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.30                      endodeoxyribonuclease PfaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.31                      endodeoxyribonuclease PstI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.32                      endodeoxyribonuclease PvuI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.33                      endodeoxyribonuclease PvuII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.34                      endodeoxyribonuclease SacI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.35                      endodeoxyribonuclease SacII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.36                      endodeoxyribonuclease SacIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.37                      endodeoxyribonuclease SalI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.38                      endodeoxyribonuclease SgrI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.39                      endodeoxyribonuclease TaqI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.40                      endodeoxyribonuclease TaqII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.41                      endodeoxyribonuclease XbaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.42                      endodeoxyribonuclease XhoI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.43                      endodeoxyribonuclease XhoII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.44                      endodeoxyribonuclease XmaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.45                      endodeoxyribonuclease XniI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.46                      endodeoxyribonuclease AimI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.47                      endodeoxyribonuclease AccI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.48                      endodeoxyribonuclease AccII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.49                      endodeoxyribonuclease AtuAI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.50                      endodeoxyribonuclease AtuBVI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.51                      endodeoxyribonuclease AcaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.52                      endodeoxyribonuclease AcyI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.53                      endodeoxyribonuclease AosI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.54                      endodeoxyribonuclease AsuII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.55                      endodeoxyribonuclease AvaIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.56                      endodeoxyribonuclease AvrII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.57                      endodeoxyribonuclease BceI4579. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bce4579I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.58                      endodeoxyribonuclease Bce1229. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bce1229I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.59                      endodeoxyribonuclease Bme899. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bme899I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.60                      endodeoxyribonuclease Bme205. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bme205I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.61                      endodeoxyribonuclease BmeI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.62                      endodeoxyribonuclease Bsp1286. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bsp1286I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.63                      endodeoxyribonuclease BstAI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.64                      endodeoxyribonuclease BstEI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.65                      endodeoxyribonuclease BstEIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.66                      endodeoxyribonuclease BstPI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.67                      endodeoxyribonuclease BsuM. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease BsuMI (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.68                      endodeoxyribonuclease Bsu6633. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. The name was misprinted in supplement 3 of the 1978 edition. Assumed to be the same as endodeoxyribonuclease Bsu6633I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.69                      endodeoxyribonuclease Bsu1145. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bsu1145I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.70                      endodeoxyribonuclease Bsu1192. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bsu1192I or see Bsu1192II (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.71                      endodeoxyribonuclease Bsu1193. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bsu1193I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.72                      endodeoxyribonuclease Bsu1231. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Not found in http://rebase.neb.com/rebase/rebase.html 
                EC 3.1.23.73                      endodeoxyribonuclease Bsu1259. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Bsu1259I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.74                      endodeoxyribonuclease ClaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.75                      endodeoxyribonuclease CauII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.76                      endodeoxyribonuclease CviI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.77                      endodeoxyribonuclease DdeI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.78                      endodeoxyribonuclease EclI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.79                      endodeoxyribonuclease EcaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.80                      endodeoxyribonuclease EcoRI′. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease EcoRI′ (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.81                      endodeoxyribonuclease Fnu48I. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.82                      endodeoxyribonuclease Fnu4H. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease Fnu4HI (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.83                      endodeoxyribonuclease HapI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.84                      endodeoxyribonuclease Hin1056II. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.85                      endodeoxyribonuclease HinfIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.86                      endodeoxyribonuclease HgiAI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.87                      endodeoxyribonuclease HgiCI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.88                      endodeoxyribonuclease HgiDI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.89                      endodeoxyribonuclease HgiEII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.90                      endodeoxyribonuclease MstI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.91                      endodeoxyribonuclease MstII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.92                      endodeoxyribonuclease MglI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.93                      endodeoxyribonuclease MglII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.94                      endodeoxyribonuclease MnoII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.95                      endodeoxyribonuclease MnnIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.96                      endodeoxyribonuclease MviI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.97                      endodeoxyribonuclease MviII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.98                      endodeoxyribonuclease OxaII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.99                      endodeoxyribonuclease PaeR7. Now EC 3.1.21.4, type II site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease PaeR7I (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.23.100                      endodeoxyribonuclease RspI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.101                      endodeoxyribonuclease RsaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.102                      endodeoxyribonuclease SmaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.103                      endodeoxyribonuclease SspI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.104                      endodeoxyribonuclease SnaI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.105                      endodeoxyribonuclease SfaNI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.106                      endodeoxyribonuclease SalII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.107                      endodeoxyribonuclease SauI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.108                      endodeoxyribonuclease SphI. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
                EC 3.1.23.109                      endodeoxyribonuclease XmaIII. Now EC 3.1.21.4, type II site-specific deoxyribonuclease 
        EC 3.1.24       []    Site specific endodeoxyribonucleases: cleavage is not sequence specific (deleted sub-subclass) 
                EC 3.1.24.1                      endodeoxyribonuclease EcoB. Now EC 3.1.21.3, type I site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease EcoBI (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.24.2                      endodeoxyribonuclease EcoK. Now EC 3.1.21.3, type I site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease EcoKI (see http://rebase.neb.com/rebase/rebase.html) 
                EC 3.1.24.3                      endodeoxyribonuclease EcoPI. Now EC 3.1.21.5, type III site-specific deoxyribonuclease. The name is misprinted in supplement 3 of the 1978 edition 
                EC 3.1.24.4                      endodeoxyribonuclease EcoP15. Now EC 3.1.21.5, type III site-specific deoxyribonuclease. Assumed to be the same as endodeoxyribonuclease EcoP15I (see http://rebase.neb.com/rebase/rebase.html) 
        EC 3.1.25       []    Site-specific endodeoxyribonucleases that are specific for altered bases 
                EC 3.1.25.1                      deoxyribonuclease (pyrimidine dimer) 
                EC 3.1.25.2                      endodeoxyribonuclease (apurinic or apyrimidinic). Now EC 4.2.99.18, DNA-(apurinic or apyrimidinic site) lyase 
        EC 3.1.26       []    Endoribonucleases producing 5'-phosphomonoesters 
                EC 3.1.26.1                      Physarum polycephalum ribonuclease 
                EC 3.1.26.2                      ribonuclease α 
                EC 3.1.26.3                      ribonuclease III 
                EC 3.1.26.4                      ribonuclease H 
                EC 3.1.26.5                      ribonuclease P 
                EC 3.1.26.6                      ribonuclease IV 
                EC 3.1.26.7                      ribonuclease P4 
                EC 3.1.26.8                      ribonuclease M5 
                EC 3.1.26.9                      ribonuclease [poly-(U)-specific] 
                EC 3.1.26.10                      ribonuclease IX 
                EC 3.1.26.11                      tRNase Z 
                EC 3.1.26.12                      ribonuclease E 
                EC 3.1.26.13                      retroviral ribonuclease H 
        EC 3.1.27       []    Endoribonucleases producing 3'-phosphomonoesters 
                EC 3.1.27.1                      ribonuclease T2. Now EC 4.6.1.19, ribonuclease T2, since the primary reaction is that of a lyase 
                EC 3.1.27.2                      Bacillus subtilis ribonuclease. Now EC 4.6.1.22, Bacillus subtilis ribonuclease, since the reaction catalysed is that of a lyase 
                EC 3.1.27.3                      ribonuclease T1. Now EC 4.6.1.24, ribonuclease T1, since the primary reaction is that of a lyase 
                EC 3.1.27.4                      ribonuclease U2. Now EC 4.6.1.20, ribonuclease U2, since the primary reaction is that of a lyase 
                EC 3.1.27.5                      pancreatic ribonuclease. Now EC 4.6.1.18, pancreatic ribonuclease. This reaction is now known to involve an internal-transfer (lyase) process to produce the cyclic derivative, followed by a reversal of that step with water in the "hydrolytic step" 
                EC 3.1.27.6                      Enterobacter ribonuclease. Now EC 4.6.1.21, Enterobacter ribonuclease, since the primary reaction is that of a lyase 
                EC 3.1.27.7                      ribonuclease F 
                EC 3.1.27.8                      ribonuclease V 
                EC 3.1.27.9                      tRNA-intron endonuclease. Now EC 4.6.1.16, tRNA-intron lyase 
                EC 3.1.27.10                      rRNA endonuclease. Now EC 4.6.1.23, ribotoxin, since the primary reaction is that of a lyase. 
        EC 3.1.30       []    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters 
                EC 3.1.30.1                      Aspergillus nuclease S1 
                EC 3.1.30.2                      Serratia marcescens nuclease 
        EC 3.1.31       []    Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters 
                EC 3.1.31.1                      micrococcal nuclease 
    EC 3.2  [+]      
        EC 3.2.1       []    Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds 
                EC 3.2.1.1                      α-amylase 
                EC 3.2.1.2                      β-amylase 
                EC 3.2.1.3                      glucan 1,4-α-glucosidase 
                EC 3.2.1.4                      cellulase 
                EC 3.2.1.5                       licheninase 
                EC 3.2.1.6                      endo-1,3(4)-β-glucanase 
                EC 3.2.1.7                      inulinase 
                EC 3.2.1.8                      endo-1,4-β-xylanase 
                EC 3.2.1.9                       amylopectin-1,6-glucosidase 
                EC 3.2.1.10                      oligo-1,6-glucosidase 
                EC 3.2.1.11                      dextranase 
                EC 3.2.1.12                       cycloheptaglucanase. Now included with EC 3.2.1.54 cyclomaltodextrinase 
                EC 3.2.1.13                       cyclohexaglucanase. Now included with EC 3.2.1.54 cyclomaltodextrinase 
                EC 3.2.1.14                      chitinase 
                EC 3.2.1.15                      endo-polygalacturonase 
                EC 3.2.1.16                       alginase 
                EC 3.2.1.17                      lysozyme 
                EC 3.2.1.18                      exo-α-sialidase 
                EC 3.2.1.19                       heparinase 
                EC 3.2.1.20                      α-glucosidase 
                EC 3.2.1.21                      β-glucosidase 
                EC 3.2.1.22                      α-galactosidase 
                EC 3.2.1.23                      β-galactosidase 
                EC 3.2.1.24                      α-mannosidase 
                EC 3.2.1.25                      β-mannosidase 
                EC 3.2.1.26                      β-fructofuranosidase 
                EC 3.2.1.27                       α-1,3-glucosidase 
                EC 3.2.1.28                      α,α-trehalase 
                EC 3.2.1.29                       chitobiase. Now included with EC 3.2.1.52, β-N-acetylhexosaminidase 
                EC 3.2.1.30                       β-D-acetylglucosaminidase. Now included with EC 3.2.1.52, β-N-acetylhexosaminidase 
                EC 3.2.1.31                      β-glucuronidase 
                EC 3.2.1.32                      endo-1,3-β-xylanase 
                EC 3.2.1.33                      amylo-α-1,6-glucosidase 
                EC 3.2.1.34                       chondroitinase. Now included with EC 3.2.1.35 hyalurononglucosaminidase 
                EC 3.2.1.35                      hyaluronoglucosaminidase 
                EC 3.2.1.36                      hyaluronoglucuronidase 
                EC 3.2.1.37                      xylan 1,4-β-xylosidase 
                EC 3.2.1.38                      β-D-fucosidase 
                EC 3.2.1.39                      glucan endo-1,3-β-D-glucosidase 
                EC 3.2.1.40                      α-L-rhamnosidase 
                EC 3.2.1.41                      pullulanase 
                EC 3.2.1.42                      GDP-glucosidase 
                EC 3.2.1.43                      β-L-rhamnosidase 
                EC 3.2.1.44                      fucoidanase. Now EC 3.2.1.211, endo-(13)-fucoidanase and EC 3.2.1.212, endo-(14)-fucoidanase 
                EC 3.2.1.45                      glucosylceramidase 
                EC 3.2.1.46                      galactosylceramidase 
                EC 3.2.1.47                      galactosylgalactosylglucosylceramidase. Now known to be catalyzed by EC 3.2.1.22, α-galactosidase. 
                EC 3.2.1.48                      sucrose α-glucosidase 
                EC 3.2.1.49                      α-N-acetylgalactosaminidase 
                EC 3.2.1.50                      α-N-acetylglucosaminidase 
                EC 3.2.1.51                      α-L-fucosidase 
                EC 3.2.1.52                      β-N-acetylhexosaminidase 
                EC 3.2.1.53                      β-N-acetylgalactosaminidase 
                EC 3.2.1.54                      cyclomaltodextrinase 
                EC 3.2.1.55                      non-reducing end α-L-arabinofuranosidase 
                EC 3.2.1.56                      glucuronosyl-disulfoglucosamine glucuronidase 
                EC 3.2.1.57                      isopullulanase 
                EC 3.2.1.58                      glucan 1,3-β-glucosidase 
                EC 3.2.1.59                      glucan endo-1,3-α-glucosidase 
                EC 3.2.1.60                      glucan 1,4-α-maltotetraohydrolase 
                EC 3.2.1.61                      mycodextranase 
                EC 3.2.1.62                      glycosylceramidase 
                EC 3.2.1.63                      1,2-α-L-fucosidase 
                EC 3.2.1.64                      2,6-β-fructan 6-levanbiohydrolase 
                EC 3.2.1.65                      levanase 
                EC 3.2.1.66                      The activity is covered by EC 3.2.1.40, α-L-rhamnosidase 
                EC 3.2.1.67                      galacturonan 1,4-α-galacturonidase 
                EC 3.2.1.68                      isoamylase 
                EC 3.2.1.69                       amylopectin 6-glucanohydrolase. Now included with EC 3.2.1.41 pullulanase 
                EC 3.2.1.70                      glucan 1,6-α-glucosidase 
                EC 3.2.1.71                      glucan endo-1,2-β-glucosidase 
                EC 3.2.1.72                      xylan 1,3-β-xylosidase 
                EC 3.2.1.73                      licheninase 
                EC 3.2.1.74                      glucan 1,4-β-glucosidase 
                EC 3.2.1.75                      glucan endo-1,6-β-glucosidase 
                EC 3.2.1.76                      L-iduronidase 
                EC 3.2.1.77                      mannan 1,2-(1,3)-α-mannosidase 
                EC 3.2.1.78                      mannan endo-1,4-β-mannosidase 
                EC 3.2.1.79                       α-L-arabinofuranoside hydrolase. Now included with EC 3.2.1.55 α-N-arabinofuranosidase 
                EC 3.2.1.80                      fructan β-fructosidase 
                EC 3.2.1.81                      β-agarase 
                EC 3.2.1.82                      exo-poly-α-digalacturonosidase 
                EC 3.2.1.83                      κ-carrageenase 
                EC 3.2.1.84                      glucan 1,3-α-glucosidase 
                EC 3.2.1.85                      6-phospho-β-galactosidase 
                EC 3.2.1.86                      6-phospho-β-glucosidase 
                EC 3.2.1.87                      capsular-polysaccharide endo-1,3-α-galactosidase 
                EC 3.2.1.88                      non-reducing end β-L-arabinopyranosidase 
                EC 3.2.1.89                      arabinogalactan endo-β-1,4-galactanase 
                EC 3.2.1.90                       arabinogalactan endo-1,3-β-galactosidase. The enzyme was not sufficiently characterized to warrant an EC number 
                EC 3.2.1.91                      cellulose 1,4-β-cellobiosidase (non-reducing end) 
                EC 3.2.1.92                      peptidoglycan β-N-acetylmuramidase 
                EC 3.2.1.93                      α,α-phosphotrehalase 
                EC 3.2.1.94                      glucan 1,6-α-isomaltosidase 
                EC 3.2.1.95                      dextran 1,6-α-isomaltotriosidase 
                EC 3.2.1.96                      mannosyl-glycoprotein endo-β-N-acetylglucosaminidase 
                EC 3.2.1.97                      endo-α-N-acetylgalactosaminidase 
                EC 3.2.1.98                      glucan 1,4-α-maltohexaosidase 
                EC 3.2.1.99                      arabinan endo-1,5-α-L-arabinanase 
                EC 3.2.1.100                      mannan 1,4-mannobiosidase 
                EC 3.2.1.101                      mannan endo-1,6-α-mannosidase 
                EC 3.2.1.102                      blood-group-substance endo-1,4-β-galactosidase 
                EC 3.2.1.103                      keratan-sulfate endo-1,4-β-galactosidase 
                EC 3.2.1.104                      steryl-β-glucosidase 
                EC 3.2.1.105                      3α(S)-strictosidine β-glucosidase 
                EC 3.2.1.106                      mannosyl-oligosaccharide glucosidase 
                EC 3.2.1.107                      protein-glucosylgalactosylhydroxylysine glucosidase 
                EC 3.2.1.108                      lactase 
                EC 3.2.1.109                      endogalactosaminidase 
                EC 3.2.1.110                      mucinaminylserine mucinaminidase. The enzyme is identical to EC 3.2.1.97, glycopeptide α-N-acetylgalactosaminidase 
                EC 3.2.1.111                      1,3-α-L-fucosidase 
                EC 3.2.1.112                      2-deoxyglucosidase 
                EC 3.2.1.113                      mannosyl-oligosaccharide 1,2-α-mannosidase 
                EC 3.2.1.114                      mannosyl-oligosaccharide 1,3-1,6-α-mannosidase 
                EC 3.2.1.115                      branched-dextran exo-1,2-α-glucosidase 
                EC 3.2.1.116                      glucan 1,4-α-maltotriohydrolase 
                EC 3.2.1.117                      amygdalin β-glucosidase 
                EC 3.2.1.118                      prunasin β-glucosidase 
                EC 3.2.1.119                      vicianin β-glucosidase 
                EC 3.2.1.120                      oligoxyloglucan β-glycosidase 
                EC 3.2.1.121                      polymannuronate hydrolase 
                EC 3.2.1.122                      maltose-6′-phosphate glucosidase 
                EC 3.2.1.123                      endoglycosylceramidase 
                EC 3.2.1.124                      3-deoxy-2-octulosonidase 
                EC 3.2.1.125                      raucaffricine β-glucosidase 
                EC 3.2.1.126                      coniferin β-glucosidase 
                EC 3.2.1.127                      1,6-α-L-fucosidase 
                EC 3.2.1.128                      glycyrrhizin hydrolase 
                EC 3.2.1.129                      endo-α-sialidase 
                EC 3.2.1.130                      glycoprotein endo-α-1,2-mannosidase 
                EC 3.2.1.131                      xylan α-1,2-glucuronosidase 
                EC 3.2.1.132                      chitosanase 
                EC 3.2.1.133                      glucan 1,4-α-maltohydrolase 
                EC 3.2.1.134                      difructose-dianhydride-I hydrolase. Now EC 4.2.1.179, difructose-dianhydride-I hydro-lyase 
                EC 3.2.1.135                      neopullulanase 
                EC 3.2.1.136                      glucuronoarabinoxylan endo-1,4-β-xylanase 
                EC 3.2.1.137                      mannan exo-1,2-1,6-α-mannosidase 
                EC 3.2.1.138                      anhydrosialidase. Now EC 4.2.2.15, anhydrosialidase 
                EC 3.2.1.139                      α-glucuronidase 
                EC 3.2.1.140                      lacto-N-biosidase 
                EC 3.2.1.141                      4-α-D-{(1→4)-α-D-glucano}trehalose trehalohydrolase 
                EC 3.2.1.142                      limit dextrinase 
                EC 3.2.1.143                      poly(ADP-ribose) glycohydrolase 
                EC 3.2.1.144                      3-deoxyoctulosonase 
                EC 3.2.1.145                      galactan 1,3-β-galactosidase 
                EC 3.2.1.146                      β-galactofuranosidase 
                EC 3.2.1.147                      thioglucosidase 
                EC 3.2.1.148                      ribosylhomocysteinase. This enzyme was transferred to EC 3.13.1.2, 5-deoxyribos-5-ylhomocysteinase, which has since been deleted. The activity is most probably attributable to EC 4.4.1.21, S-ribosylhomocysteine lyase 
                EC 3.2.1.149                      β-primeverosidase 
                EC 3.2.1.150                      oligoxyloglucan reducing-end-specific cellobiohydrolase 
                EC 3.2.1.151                      xyloglucan-specific endo-β-1,4-glucanase 
                EC 3.2.1.152                      mannosylglycoprotein endo-β-mannosidase 
                EC 3.2.1.153                      fructan β-(2,1)-fructosidase 
                EC 3.2.1.154                      fructan β-(2,6)-fructosidase 
                EC 3.2.1.155                      xyloglucan-specific endo-processive β-1,4-glucanase 
                EC 3.2.1.156                      oligosaccharide reducing-end xylanase 
                EC 3.2.1.157                      ι-carrageenase 
                EC 3.2.1.158                      α-agarase 
                EC 3.2.1.159                      α-neoagaro-oligosaccharide hydrolase 
                EC 3.2.1.160                      xyloglucan-specific exo-β-1,4-glucanase. The enzyme was shown to be identical to EC 3.2.1.155, xyloglucan-specific exo-β-1,4-glucanase, during the public-review process so was withdrawn before being made official 
                EC 3.2.1.161                      β-apiosyl-β-glucosidase 
                EC 3.2.1.162                      λ-carrageenase 
                EC 3.2.1.163                      1,6-α-D-mannosidase 
                EC 3.2.1.164                      galactan endo-1,6-β-galactosidase 
                EC 3.2.1.165                      exo-1,4-β-D-glucosaminidase 
                EC 3.2.1.166                      heparanase 
                EC 3.2.1.167                      baicalin-β-D-glucuronidase 
                EC 3.2.1.168                      hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase 
                EC 3.2.1.169                      protein O-GlcNAcase 
                EC 3.2.1.170                      mannosylglycerate hydrolase 
                EC 3.2.1.171                      rhamnogalacturonan hydrolase 
                EC 3.2.1.172                      unsaturated rhamnogalacturonyl hydrolase 
                EC 3.2.1.173                      rhamnogalacturonan galacturonohydrolase 
                EC 3.2.1.174                      rhamnogalacturonan rhamnohydrolase 
                EC 3.2.1.175                      β-D-glucopyranosyl abscisate β-glucosidase 
                EC 3.2.1.176                      cellulose 1,4-β-cellobiosidase (reducing end) 
                EC 3.2.1.177                      α-D-xyloside xylohydrolase 
                EC 3.2.1.178                      β-porphyranase 
                EC 3.2.1.179                      gellan tetrasaccharide unsaturated glucuronosyl hydrolase 
                EC 3.2.1.180                      unsaturated chondroitin disaccharide hydrolase 
                EC 3.2.1.181                      galactan endo-β-1,3-galactanase 
                EC 3.2.1.182                      4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase 
                EC 3.2.1.183                      UDP-N-acetylglucosamine 2-epimerase (hydrolysing) 
                EC 3.2.1.184                      UDP-N,N′-diacetylbacillosamine 2-epimerase (hydrolysing) 
                EC 3.2.1.185                      non-reducing end β-L-arabinofuranosidase 
                EC 3.2.1.186                      protodioscin 26-O-β-D-glucosidase 
                EC 3.2.1.187                      (Ara-f)3-Hyp β-L-arabinobiosidase 
                EC 3.2.1.188                      avenacosidase 
                EC 3.2.1.189                      dioscin glycosidase (diosgenin-forming)  
                EC 3.2.1.190                      dioscin glycosidase (3-O-β-D-Glc-diosgenin-forming)  
                EC 3.2.1.191                      ginsenosidase type III 
                EC 3.2.1.192                      ginsenoside Rb1 β-glucosidase 
                EC 3.2.1.193                      ginsenosidase type I 
                EC 3.2.1.194                      ginsenosidase type IV 
                EC 3.2.1.195                      20-O-multi-glycoside ginsenosidase  
                EC 3.2.1.196                      limit dextrin α-1,6-maltotetraose-hydrolase 
                EC 3.2.1.197                      β-1,2-mannosidase 
                EC 3.2.1.198                      α-mannan endo-1,2-α-mannanase 
                EC 3.2.1.199                      sulfoquinovosidase 
                EC 3.2.1.200                      exo-chitinase (non-reducing end) 
                EC 3.2.1.201                      exo-chitinase (reducing end) 
                EC 3.2.1.202                      endo-chitodextinase 
                EC 3.2.1.203                      carboxymethylcellulase 
                EC 3.2.1.204                      1,3-α-isomaltosidase 
                EC 3.2.1.205                      isomaltose glucohydrolase 
                EC 3.2.1.206                      oleuropein β-glucosidase 
                EC 3.2.1.207                      mannosyl-oligosaccharide α-1,3-glucosidase 
                EC 3.2.1.208                      glucosylglycerate hydrolase 
                EC 3.2.1.209                      endoplasmic reticulum Man9GlcNAc2 1,2-α-mannosidase 
                EC 3.2.1.210                      endoplasmic reticulum Man8GlcNAc2 1,2-α-mannosidase 
                EC 3.2.1.211                      endo-(1→3)-fucoidanase 
                EC 3.2.1.212                      endo-(1→4)-fucoidanase 
                EC 3.2.1.213                      galactan exo-1,6-β-galactobiohydrolase (non-reducing end) 
                EC 3.2.1.214                      exo β-1,2-glucooligosaccharide sophorohydrolase (non-reducing end) 
                EC 3.2.1.215                      arabinogalactan exo α-(1,3)-α-D-galactosyl-(1→3)-L-arabinofuranosidase (non-reducing end) 
                EC 3.2.1.216                      kojibiose hydrolase 
                EC 3.2.1.217                      exo-acting protein-α-N-acetylgalactosaminidase 
                EC 3.2.1.218                      α-3′-ketoglucosidase 
                EC 3.2.1.219                      palatinase 
                EC 3.2.1.220                      ipecoside β-D-glucosidase 
                EC 3.2.1.221                      MMP endo-(1,4)-3-O-methyl-α-D-mannosidase 
                EC 3.2.1.222                      funoran endo-β-hydrolase 
                EC 3.2.1.223                      arabinogalactan exo α-(1,3)-β-L-arabinopyranosyl-(1→3)-L-arabinofuranosidase (non-reducing end) 
        EC 3.2.2       []    Hydrolysing N-glycosyl compounds 
                EC 3.2.2.1                      purine nucleosidase 
                EC 3.2.2.2                      inosine nucleosidase 
                EC 3.2.2.3                      uridine nucleosidase 
                EC 3.2.2.4                      AMP nucleosidase 
                EC 3.2.2.5                      NAD+ glycohydrolase 
                EC 3.2.2.6                      ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 
                EC 3.2.2.7                      adenosine nucleosidase 
                EC 3.2.2.8                      ribosylpyrimidine nucleosidase 
                EC 3.2.2.9                      adenosylhomocysteine nucleosidase 
                EC 3.2.2.10                      pyrimidine-5′-nucleotide nucleosidase 
                EC 3.2.2.11                      β-aspartyl-N-acetylglucosaminidase 
                EC 3.2.2.12                      inosinate nucleosidase 
                EC 3.2.2.13                      1-methyladenosine nucleosidase 
                EC 3.2.2.14                      NMN nucleosidase 
                EC 3.2.2.15                      DNA-deoxyinosine glycosylase 
                EC 3.2.2.16                      methylthioadenosine nucleosidase 
                EC 3.2.2.17                      deoxyribodipyrimidine endonucleosidase 
                EC 3.2.2.18                       glycopeptide N-glycosidase. Now included with EC 3.5.1.52, peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase 
                EC 3.2.2.19                      [protein ADP-ribosylarginine] hydrolase 
                EC 3.2.2.20                      DNA-3-methyladenine glycosylase I 
                EC 3.2.2.21                      DNA-3-methyladenine glycosylase II 
                EC 3.2.2.22                      rRNA N-glycosylase 
                EC 3.2.2.23                      DNA-formamidopyrimidine glycosylase 
                EC 3.2.2.24                      ADP-ribosyl-[dinitrogen reductase] hydrolase 
                EC 3.2.2.25                      N-methyl nucleosidase 
                EC 3.2.2.26                      futalosine hydrolase 
                EC 3.2.2.27                      uracil-DNA glycosylase 
                EC 3.2.2.28                      double-stranded uracil-DNA glycosylase 
                EC 3.2.2.29                      thymine-DNA glycosylase 
                EC 3.2.2.30                      aminodeoxyfutalosine nucleosidase 
                EC 3.2.2.31                      adenine glycosylase 
        EC 3.2.3       []    Hydrolysing S-glycosyl compounds (deleted sub-subclass) 
                EC 3.2.3.1                      thioglucosidase. Now EC 3.2.1.147, thioglucosidase 
    EC 3.3  [+]      
        EC 3.3.1       []      
                EC 3.3.1.1                      adenosylhomocysteinase, now classified as EC 3.13.2.1, adenosylhomocysteinase 
                EC 3.3.1.2                      S-adenosyl-L-methionine hydrolase (L-homoserine-forming), now classified as EC 3.13.2.2, S-adenosyl-L-methionine hydrolase (L-homoserine-forming) 
                EC 3.3.1.3                      ribosylhomocysteinase. This enzyme was transferred to EC 3.2.1.148, ribosylhomocysteinase, which has since been deleted. The activity is most probably attributable to EC 4.4.1.21, S-ribosylhomocysteine lyase 
        EC 3.3.2       []    Ether hydrolases 
                EC 3.3.2.1                      isochorismatase 
                EC 3.3.2.2                      lysoplasmalogenase 
                EC 3.3.2.3                      epoxide hydrolase. Now known to comprise two enzymes, microsomal epoxide hydrolase (EC 3.3.2.9) and soluble epoxide hydrolase (EC 3.3.2.10) 
                EC 3.3.2.4                      trans-epoxysuccinate hydrolase 
                EC 3.3.2.5                      alkenylglycerophosphoethanolamine hydrolase. Now included in EC 3.3.2.2, lysoplasmalogenase. 
                EC 3.3.2.6                      leukotriene-A4 hydrolase 
                EC 3.3.2.7                      hepoxilin-epoxide hydrolase 
                EC 3.3.2.8                      limonene-1,2-epoxide hydrolase 
                EC 3.3.2.9                      microsomal epoxide hydrolase 
                EC 3.3.2.10                      soluble epoxide hydrolase 
                EC 3.3.2.11                      cholesterol-5,6-oxide hydrolase 
                EC 3.3.2.12                      oxepin-CoA hydrolase 
                EC 3.3.2.13                      chorismatase 
                EC 3.3.2.14                      2,4-dinitroanisole O-demethylase 
                EC 3.3.2.15                      trans-2,3-dihydro-3-hydroxyanthranilic acid synthase 
    EC 3.4  [+]      
        EC 3.4.1       []    α-Amino-acyl-peptide hydrolases (deleted sub-subclass) 
                EC 3.4.1.1                      leucyl aminopeptidase. Now EC 3.4.11.1, leucyl aminopeptidase 
                EC 3.4.1.2                      aminopeptidase. Now EC 3.4.11.2, membrane alanyl aminopeptidase 
                EC 3.4.1.3                      aminotripeptidase. Now EC 3.4.11.4, tripeptide aminopeptidase 
                EC 3.4.1.4                      proline iminopeptidase. Now EC 3.4.11.5, prolyl aminopeptidase 
        EC 3.4.2       []    Peptidyl-amino-acid hydrolases (deleted sub-subclass) 
                EC 3.4.2.1                      carboxypeptidase A. Now EC 3.4.17.1, carboxypeptidase A 
                EC 3.4.2.2                      carboxypeptidase B. Now EC 3.4.17.2, carboxypeptidase B 
                EC 3.4.2.3                      yeast carboxypeptidase. Now EC 3.4.17.4, Gly-Xaa carboxypeptidase 
        EC 3.4.3       []    Dipeptide hydrolases (deleted sub-subclass) 
                EC 3.4.3.1                      glycyl-glycine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.3.2                      glycyl-leucine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.3.3                      aminoacyl-histidine dipeptidase. Now EC 3.4.13.3, Xaa-His dipeptidase 
                EC 3.4.3.4                      aminoacyl-methylhistidine dipeptidase. Now EC 3.4.13.5, Xaa-methyl-His dipeptidase 
                EC 3.4.3.5                      cysteinylglycine dipeptidase. Now EC 3.4.11.2, membrane alanyl aminopeptidase 
                EC 3.4.3.6                      iminodipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.3.7                      iminodipeptidase. Now EC 3.4.13.9, Xaa-Pro dipeptidase 
        EC 3.4.4       []    Peptidyl peptide hydrolases (deleted sub-subclass) 
                EC 3.4.4.1                      pepsin. Now EC 3.4.23.1, pepsin A 
                EC 3.4.4.2                      pepsin B. Now EC 3.4.23.2, pepsin B 
                EC 3.4.4.3                      rennin. Now EC 3.4.23.4, chymosin 
                EC 3.4.4.4                      trypsin. Now EC 3.4.21.4, trypsin 
                EC 3.4.4.5                      chymotrypsin. Now EC 3.4.21.1, chymotrypsin 
                EC 3.4.4.6                      chymotrypsin B. Now EC 3.4.21.1, chymotrypsin 
                EC 3.4.4.7                      elastase. Now covered by EC 3.4.21.36, pancreatic elastase and EC 3.4.21.37, leukocyte elastase 
                EC 3.4.4.8                      enteropeptidase. Now EC 3.4.21.9, enteropeptidase 
                EC 3.4.4.9                      cathepsin C. Now EC 3.4.14.1, dipeptidyl-peptidase I 
                EC 3.4.4.10                      papain. Now EC 3.4.22.2, papain 
                EC 3.4.4.11                      chymopapain. Now EC 3.4.22.6, chymopapain 
                EC 3.4.4.12                      ficin. Now EC 3.4.22.3, ficain 
                EC 3.4.4.13                      thrombin. Now EC 3.4.21.5, thrombin 
                EC 3.4.4.14                      plasmin. Now EC 3.4.21.7, plasmin 
                EC 3.4.4.15                      renin. Now EC 3.4.23.15, renin 
                EC 3.4.4.16                      subtilopeptidase A. Now covered by the microbial serine proteinases EC 3.4.21.62 (subtilisin), EC 3.4.21.63 (oryzin), EC 3.4.21.64 (endopeptidase K), EC 3.4.21.65 (thermomycolin), EC 3.4.21.66 (thermitase) and EC 3.4.21.67 (ndopeptidase So) 
                EC 3.4.4.17                      aspergillopeptidase A. Now covered by the microbial aspartic proteinases EC 3.4.23.20 (penicillopepsin), EC 3.4.23.21 (rhizopuspepsin), EC 3.4.23.22 (endothiapepsin), EC 3.4.23.23 (mucorpepsin), EC 3.4.23.24 (candidapepsin), EC 3.4.23.25 (saccharopepsin), EC 3.4.23.26 (rhodotorulapepsin), EC 3.4.21.103 (physarolisin), EC 3.4.23.28 (acrocylindropepsin), EC 3.4.23.29 (polyporopepsin) and EC 3.4.23.30 (pycnoporopepsin) 
                EC 3.4.4.18                      streptococcus peptidase A. Now EC 3.4.22.10, streptopain 
                EC 3.4.4.19                      clostridiopeptidase A. Now EC 3.4.24.3, microbial collagenase 
                EC 3.4.4.20                      clostridiopeptidase B. Now EC 3.4.22.8, clostripain 
                EC 3.4.4.21                      kallikrein. Now EC 3.4.21.34 (plasma kallikrein) and EC 3.4.21.35 (tissue kallikrein) 
                EC 3.4.4.22                      now EC 3.4.23.3, gastricsin 
                EC 3.4.4.23                      now EC 3.4.23.5, cathepsin D 
                EC 3.4.4.24                      now covered by EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain) 
                EC 3.4.4.25                      Streptomyces alkalophilic keratinase 
        EC 3.4.11       []    Aminopeptidases 
                EC 3.4.11.1                      leucyl aminopeptidase 
                EC 3.4.11.2                      membrane alanyl aminopeptidase 
                EC 3.4.11.3                      cystinyl aminopeptidase 
                EC 3.4.11.4                      tripeptide aminopeptidase 
                EC 3.4.11.5                      prolyl aminopeptidase 
                EC 3.4.11.6                      aminopeptidase B 
                EC 3.4.11.7                      glutamyl aminopeptidase 
                EC 3.4.11.8                      pyroglutamyl aminopeptidase. Now EC 3.4.19.3, pyroglutamyl-peptidase I 
                EC 3.4.11.9                      Xaa-Pro aminopeptidase 
                EC 3.4.11.10                      bacterial leucyl aminopeptidase 
                EC 3.4.11.11                       aminopeptidase 
                EC 3.4.11.12                       thermophilic aminopeptidase 
                EC 3.4.11.13                      clostridial aminopeptidase 
                EC 3.4.11.14                      cytosol alanyl aminopeptidase 
                EC 3.4.11.15                      aminopeptidase Y 
                EC 3.4.11.16                      Xaa-Trp aminopeptidase 
                EC 3.4.11.17                      tryptophanyl aminopeptidase 
                EC 3.4.11.18                      methionyl aminopeptidase 
                EC 3.4.11.19                      D-stereospecific aminopeptidase 
                EC 3.4.11.20                      aminopeptidase Ey 
                EC 3.4.11.21                      aspartyl aminopeptidase 
                EC 3.4.11.22                      aminopeptidase I 
                EC 3.4.11.23                      PepB aminopeptidase 
                EC 3.4.11.24                      aminopeptidase S 
                EC 3.4.11.25                      β-peptidyl aminopeptidase 
                EC 3.4.11.26                      intermediate cleaving peptidase 55 
                EC 3.4.11.27                      archaeal arginyl aminopeptidase 
        EC 3.4.12       []    Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass) 
                EC 3.4.12.1                      now EC 3.4.16.5 (carboxypeptidase C) and EC 3.4.16.6 (carboxypeptidase D) 
                EC 3.4.12.2                      now EC 3.4.17.1, carboxypeptidase A 
                EC 3.4.12.3                      now EC 3.4.17.2, carboxypeptidase B 
                EC 3.4.12.4                      now EC 3.4.16.2, lysosomal Pro-Xaa carboxypeptidase 
                EC 3.4.12.5                      now EC 3.5.1.28, N-acetylmuramoyl-L-alanine amidase 
                EC 3.4.12.6                      now EC 3.4.17.8, muramoyl-pentapeptidase carboxypeptidase 
                EC 3.4.12.7                      now EC 3.4.17.3, lysine carboxypeptidase 
                EC 3.4.12.8                      now EC 3.4.17.4, Gly-Xaa carboxypeptidase 
                EC 3.4.12.9                      aspartate carboxypeptidase 
                EC 3.4.12.10                      now EC 3.4.19.9, γ-glutamyl hydrolase 
                EC 3.4.12.11                      now EC 3.4.17.6, alanine carboxypeptidase 
                EC 3.4.12.12                      now EC 3.4.16.5 (carboxypeptidase C) and EC 3.4.16.6 (carboxypeptidase D) 
                EC 3.4.12.13                      γ-glutamylglutamate carboxypeptidase 
        EC 3.4.13       []    Dipeptidases 
                EC 3.4.13.1                      glycyl-glycine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.13.2                      glycyl-leucine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.13.3                      Xaa-His dipeptidase. The activity is covered by EC 3.4.13.18, cytosol nonspecific dipeptidase and EC 3.4.13.20, β-Ala-His dipeptidase. 
                EC 3.4.13.4                      Xaa-Arg dipeptidase 
                EC 3.4.13.5                      Xaa-methyl-His dipeptidase 
                EC 3.4.13.6                      Cys-Gly dipeptidase. Now EC 3.4.11.2, membrane alanyl aminopeptidase 
                EC 3.4.13.7                      Glu-Glu dipeptidase 
                EC 3.4.13.8                      Pro-X dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.13.9                      Xaa-Pro dipeptidase 
                EC 3.4.13.10                      β-aspartyldipeptidase. Now EC 3.4.19.5, β-aspartyl-peptidase 
                EC 3.4.13.11                      dipeptidase. Now EC 3.4.13.19, membrane dipeptidase 
                EC 3.4.13.12                      Met-Xaa dipeptidase 
                EC 3.4.13.13                      homocarnosinase. Now EC 3.4.13.3, X-His dipeptidase 
                EC 3.4.13.14                       γ-glutamyldipeptidase 
                EC 3.4.13.15                      N2-β-alanylarginine dipeptidase. Now EC 3.4.13.18, cytosol nonspecific dipeptidase 
                EC 3.4.13.16                       aspartylphenylalanine dipeptidase 
                EC 3.4.13.17                      non-stereospecific dipeptidase 
                EC 3.4.13.18                      cytosol nonspecific dipeptidase 
                EC 3.4.13.19                      membrane dipeptidase 
                EC 3.4.13.20                      β-Ala-His dipeptidase 
                EC 3.4.13.21                      dipeptidase E 
                EC 3.4.13.22                      D-Ala-D-Ala dipeptidase 
                EC 3.4.13.23                      cysteinylglycine-S-conjugate dipeptidase 
        EC 3.4.14       []    Dipeptidyl-peptidases and tripeptidyl-peptidases 
                EC 3.4.14.1                      dipeptidyl-peptidase I 
                EC 3.4.14.2                      dipeptidyl-peptidase II 
                EC 3.4.14.3                      acylamino-acid-releasing enzyme. Now EC 3.4.19.1, acylaminoacyl-peptidase 
                EC 3.4.14.4                      dipeptidyl-peptidase III 
                EC 3.4.14.5                      dipeptidyl-peptidase IV 
                EC 3.4.14.6                      dipeptidyl-dipeptidase 
                EC 3.4.14.7                       tetralysine endopeptidase 
                EC 3.4.14.8                      tripeptidyl peptidase. Now EC 3.4.14.10, tripeptidyl-peptidase II 
                EC 3.4.14.9                      tripeptidyl-peptidase I 
                EC 3.4.14.10                      tripeptidyl-peptidase II 
                EC 3.4.14.11                      Xaa-Pro dipeptidyl-peptidase 
                EC 3.4.14.12                      Xaa-Xaa-Pro tripeptidyl-peptidase 
                EC 3.4.14.13                      γ-D-glutamyl-L-lysine dipeptidyl-peptidase 
                EC 3.4.14.14                      [mycofactocin precursor peptide] peptidase 
        EC 3.4.15       []    Peptidyl-dipeptidases 
                EC 3.4.15.1                      peptidyl-dipeptidase A 
                EC 3.4.15.2                      pepdidyl carboxyamidase. Now EC 3.4.19.2, peptidyl-glycinamidase 
                EC 3.4.15.3                      dipeptidyl carboxypeptidase. Now EC 3.4.15.5, peptidyl-dipeptidase Dcp 
                EC 3.4.15.4                      peptidyl-dipeptidase B 
                EC 3.4.15.5                      peptidyl-dipeptidase Dcp 
                EC 3.4.15.6                      cyanophycinase 
        EC 3.4.16       []    Serine-type carboxypeptidases 
                EC 3.4.16.1                      serine carboxypeptidase. Now EC 3.4.16.6, carboxypeptidase D 
                EC 3.4.16.2                      lysosomal Pro-Xaa carboxypeptidase 
                EC 3.4.16.3                      tyrosine carboxypeptidase. Now included with EC 3.4.16.5, carboxypeptidase C 
                EC 3.4.16.4                      serine-type D-Ala-D-Ala carboxypeptidase 
                EC 3.4.16.5                      carboxypeptidase C 
                EC 3.4.16.6                      carboxypeptidase D 
        EC 3.4.17       []    Metallocarboxypeptidases 
                EC 3.4.17.1                      carboxypeptidase A 
                EC 3.4.17.2                      carboxypeptidase B 
                EC 3.4.17.3                      lysine carboxypeptidase 
                EC 3.4.17.4                      Gly-Xaa carboxypeptidase 
                EC 3.4.17.5                      aspartate carboxypeptidase 
                EC 3.4.17.6                      alanine carboxypeptidase 
                EC 3.4.17.7                      acylmuramoyl-alanine carboxypeptidase. Now EC 3.5.1.28, N-acetylmuramoyl-L-alanine amidase 
                EC 3.4.17.8                      muramoylpentapeptide carboxypeptidase 
                EC 3.4.17.9                      carboxypeptidase S. Now included with EC 3.4.17.4, Gly-Xaa carboxypeptidase 
                EC 3.4.17.10                      carboxypeptidase E 
                EC 3.4.17.11                      glutamate carboxypeptidase 
                EC 3.4.17.12                      carboxypeptidase M 
                EC 3.4.17.13                      muramoyltetrapeptide carboxypeptidase 
                EC 3.4.17.14                      zinc D-Ala-D-Ala carboxypeptidase 
                EC 3.4.17.15                      carboxypeptidase A2 
                EC 3.4.17.16                      membrane Pro-Xaa carboxypeptidase 
                EC 3.4.17.17                      tubulinyl-Tyr carboxypeptidase 
                EC 3.4.17.18                      carboxypeptidase T 
                EC 3.4.17.19                      carboxypeptidase Taq 
                EC 3.4.17.20                      carboxypeptidase U 
                EC 3.4.17.21                      glutamate carboxypeptidase II 
                EC 3.4.17.22                      metallocarboxypeptidase D 
                EC 3.4.17.23                      angiotensin-converting enzyme 2 
                EC 3.4.17.24                      tubulin-glutamate carboxypeptidase 
                EC 3.4.17.25                      glutathione-S-conjugate glycine hydrolase 
        EC 3.4.18       []    Cysteine-type carboxypeptidases 
                EC 3.4.18.1                      cathepsin X 
        EC 3.4.19       []    Omega peptidases 
                EC 3.4.19.1                      acylaminoacyl-peptidase 
                EC 3.4.19.2                      peptidyl-glycinamidase 
                EC 3.4.19.3                      pyroglutamyl-peptidase I 
                EC 3.4.19.4                       N-acetylmethionylpeptide peptidase 
                EC 3.4.19.5                      β-aspartyl-peptidase 
                EC 3.4.19.6                      pyroglutamyl-peptidase II 
                EC 3.4.19.7                      N-formylmethionyl-peptidase 
                EC 3.4.19.8                      now EC 3.4.17.21, glutamate carboxypeptidase II 
                EC 3.4.19.9                      folate γ-glutamyl hydrolase 
                EC 3.4.19.10                      acylmuramoyl-Ala peptidase. Now EC 3.5.1.28, N-acetylmuramoyl-L-alanine amidase 
                EC 3.4.19.11                      γ-D-glutamyl-meso-diaminopimelate peptidase 
                EC 3.4.19.12                      ubiquitinyl hydrolase 1 
                EC 3.4.19.13                      glutathione γ-glutamate hydrolase 
                EC 3.4.19.14                      leukotriene-C4 hydrolase 
                EC 3.4.19.15                      desampylase 
                EC 3.4.19.16                      glucosinolate γ-glutamyl hydrolase 
        EC 3.4.21       []    Serine endopeptidases 
                EC 3.4.21.1                      chymotrypsin 
                EC 3.4.21.2                      chymotrypsin C 
                EC 3.4.21.3                      metridin 
                EC 3.4.21.4                      trypsin 
                EC 3.4.21.5                      thrombin 
                EC 3.4.21.6                      coagulation factor Xa 
                EC 3.4.21.7                      plasmin 
                EC 3.4.21.8                      kallikrein. Now EC 3.4.21.34 (plasma kallikrein) and EC 3.4.21.35 (tissue kallikrein) 
                EC 3.4.21.9                      enteropeptidase 
                EC 3.4.21.10                      acrosin 
                EC 3.4.21.11                      elastase. Now EC 3.4.21.37, leukocyte elastase 
                EC 3.4.21.12                      α-lytic endopeptidase 
                EC 3.4.21.13                      Phaseolus proteinase. Now EC 3.4.16.6, carboxypeptidase D 
                EC 3.4.21.14                      now EC 3.4.21.67 endopeptidase So 
                EC 3.4.21.15                      Aspergillus alkaline proteinase. Now EC 3.4.21.63, oryzin 
                EC 3.4.21.16                      Alternaria serine proteinase 
                EC 3.4.21.17                       Arthrobacter serine proteinase 
                EC 3.4.21.18                      Tenebrio α-proteinase 
                EC 3.4.21.19                      glutamyl endopeptidase 
                EC 3.4.21.20                      cathepsin G 
                EC 3.4.21.21                      coagulation factor VIIa 
                EC 3.4.21.22                      coagulation factor IXa 
                EC 3.4.21.23                       Vipera russelli proteinase 
                EC 3.4.21.24                       red cell neutral endopeptidase 
                EC 3.4.21.25                      cucumisin 
                EC 3.4.21.26                      prolyl oligopeptidase 
                EC 3.4.21.27                      coagulation factor XIa 
                EC 3.4.21.28                      Agkistrodon serine proteinase. Now EC 3.4.21.74, venombin A 
                EC 3.4.21.29                      Bothrops atrox serine proteinase. Now EC 3.4.21.74, venombin A 
                EC 3.4.21.30                      Crotalus adamanteus serine proteinase. Now EC 3.4.21.74, venombin A 
                EC 3.4.21.31                      urokinase. Now EC 3.4.21.73, u-plasminogen activator 
                EC 3.4.21.32                      brachyurin 
                EC 3.4.21.33                      Entomophthora collagenolytic proteinase 
                EC 3.4.21.34                      plasma kallikrein 
                EC 3.4.21.35                      tissue kallikrein 
                EC 3.4.21.36                      pancreatic elastase 
                EC 3.4.21.37                      leukocyte elastase 
                EC 3.4.21.38                      coagulation factor XIIa 
                EC 3.4.21.39                      chymase 
                EC 3.4.21.40                       submandibular proteinase A 
                EC 3.4.21.41                      complement subcomponent C1r 
                EC 3.4.21.42                      complement subcomponent C1s 
                EC 3.4.21.43                      classical-complement-pathway C3/C5 convertase 
                EC 3.4.21.44                      complement component C5 convertase. Now EC 3.4.21.43, classical-complement-pathway C3/C5 convertase 
                EC 3.4.21.45                      complement factor I 
                EC 3.4.21.46                      complement factor D 
                EC 3.4.21.47                      alternative-complement-pathway C3/C5 convertase 
                EC 3.4.21.48                      cerevisin 
                EC 3.4.21.49                      hypodermin C 
                EC 3.4.21.50                      lysyl endopeptidase 
                EC 3.4.21.51                       Leukocyte-membrane neutral endopeptidase 
                EC 3.4.21.52                       Cathepsin R 
                EC 3.4.21.53                      endopeptidase La 
                EC 3.4.21.54                      γ-renin 
                EC 3.4.21.55                      venombin AB 
                EC 3.4.21.56                      euphorbain. Now considered EC 3.4.21.25, cucumisin 
                EC 3.4.21.57                      leucyl endopeptidase 
                EC 3.4.21.58                       prohormone serine proteinase 
                EC 3.4.21.59                      tryptase 
                EC 3.4.21.60                      scutelarin 
                EC 3.4.21.61                      kexin 
                EC 3.4.21.62                      subtilisin 
                EC 3.4.21.63                      oryzin 
                EC 3.4.21.64                      peptidase K 
                EC 3.4.21.65                      thermomycolin 
                EC 3.4.21.66                      thermitase 
                EC 3.4.21.67                      endopeptidase So 
                EC 3.4.21.68                      t-plasminogen activator 
                EC 3.4.21.69                      protein C (activated) 
                EC 3.4.21.70                      pancreatic endopeptidase E 
                EC 3.4.21.71                      pancreatic elastase II 
                EC 3.4.21.72                      IgA-specific serine endopeptidase 
                EC 3.4.21.73                      u-plasminogen activator 
                EC 3.4.21.74                      venombin A 
                EC 3.4.21.75                      furin 
                EC 3.4.21.76                      myeloblastin 
                EC 3.4.21.77                      semenogelase 
                EC 3.4.21.78                      granzyme A 
                EC 3.4.21.79                      granzyme B 
                EC 3.4.21.80                      streptogrisin A 
                EC 3.4.21.81                      streptogrisin B 
                EC 3.4.21.82                      glutamyl endopeptidase II 
                EC 3.4.21.83                      oligopeptidase B 
                EC 3.4.21.84                      limulus clotting factor C 
                EC 3.4.21.85                      limulus clotting factor B 
                EC 3.4.21.86                      limulus clotting enzyme 
                EC 3.4.21.87                      omptin. Now EC 3.4.23.49, omptin. The enzyme is not a serine protease, as thought previously, but an aspartate protease 
                EC 3.4.21.88                      repressor LexA 
                EC 3.4.21.89                      signal peptidase I 
                EC 3.4.21.90                      togavirin 
                EC 3.4.21.91                      flavivirin 
                EC 3.4.21.92                      endopeptidase Clp 
                EC 3.4.21.93                      proprotein convertase 1 
                EC 3.4.21.94                      proprotein convertase 2 
                EC 3.4.21.95                      snake venom factor V activator 
                EC 3.4.21.96                      lactocepin 
                EC 3.4.21.97                      assemblin 
                EC 3.4.21.98                      hepacivirin 
                EC 3.4.21.99                      spermosin 
                EC 3.4.21.100                      sedolisin 
                EC 3.4.21.101                      xanthomonalisin 
                EC 3.4.21.102                      C-terminal processing peptidase 
                EC 3.4.21.103                      physarolisin 
                EC 3.4.21.104                      mannan-binding lectin-associated serine protease-2 
                EC 3.4.21.105                      rhomboid protease 
                EC 3.4.21.106                      hepsin 
                EC 3.4.21.107                      peptidase Do 
                EC 3.4.21.108                      HtrA2 peptidase 
                EC 3.4.21.109                      matriptase 
                EC 3.4.21.110                      C5a peptidase 
                EC 3.4.21.111                      aqualysin 1 
                EC 3.4.21.112                      site-1 protease 
                EC 3.4.21.113                      pestivirus NS3 polyprotein peptidase 
                EC 3.4.21.114                      equine arterivirus serine peptidase 
                EC 3.4.21.115                      infectious pancreatic necrosis birnavirus Vp4 peptidase 
                EC 3.4.21.116                      SpoIVB peptidase 
                EC 3.4.21.117                      stratum corneum chymotryptic enzyme 
                EC 3.4.21.118                      kallikrein 8 
                EC 3.4.21.119                      kallikrein 13 
                EC 3.4.21.120                      oviductin 
                EC 3.4.21.121                      Lys-Lys/Arg-Xaa endopeptidase 
                EC 3.4.21.122                      transmembrane protease serine 2 
                EC 3.4.21.123                      kumamolysin 
        EC 3.4.22       []    Cysteine endopeptidases 
                EC 3.4.22.1                      cathepsin B 
                EC 3.4.22.2                      papain 
                EC 3.4.22.3                      ficain 
                EC 3.4.22.4                      bromelain (stem). Now EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain) 
                EC 3.4.22.5                      bromelain (juice). Now EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain) 
                EC 3.4.22.6                      chymopapain 
                EC 3.4.22.7                      asclepain 
                EC 3.4.22.8                      clostripain 
                EC 3.4.22.9                      yeast proteinase B. Now EC 3.4.21.48, cerevisin 
                EC 3.4.22.10                      streptopain 
                EC 3.4.22.11                      insulinase. Now EC 3.4.24.56, insulysin 
                EC 3.4.22.12                      γ-glutamyl hydrolase. Now EC 3.4.19.9, γ-glutamyl hydrolase 
                EC 3.4.22.13                       staphylococcal cysteine proteinase 
                EC 3.4.22.14                      actinidain 
                EC 3.4.22.15                      cathepsin L 
                EC 3.4.22.16                      cathepsin H 
                EC 3.4.22.17                      calpain. Now EC 3.4.22.53, calpain-2 
                EC 3.4.22.18                      prolyl endopeptidase (thiol-dependent). Now EC 3.4.21.26, prolyl oligopeptidase 
                EC 3.4.22.19                      endo-oligopeptidase. Now EC 3.4.24.15, thimet oligopeptidase 
                EC 3.4.22.20                       dinorphin-converting enzyme 
                EC 3.4.22.21                      yeast cysteine proteinase E. Now EC 3.4.25.1, proteasome endopeptidase complex 
                EC 3.4.22.22                      yeast cysteine proteinase D. Now EC 3.4.24.37, saccharolysin 
                EC 3.4.22.23                      yeast cysteine proteinase F. Now EC 3.4.21.61, kexin 
                EC 3.4.22.24                      cathepsin T 
                EC 3.4.22.25                      glycyl endopeptidase 
                EC 3.4.22.26                      cancer procoagulant 
                EC 3.4.22.27                      cathepsin S 
                EC 3.4.22.28                      picornain 3C 
                EC 3.4.22.29                      picornain 2A 
                EC 3.4.22.30                      caricain 
                EC 3.4.22.31                      ananain 
                EC 3.4.22.32                      stem bromelain 
                EC 3.4.22.33                      fruit bromelain 
                EC 3.4.22.34                      legumain 
                EC 3.4.22.35                      histolysain 
                EC 3.4.22.36                      caspase-1 
                EC 3.4.22.37                      gingipain R 
                EC 3.4.22.38                      cathepsin K 
                EC 3.4.22.39                      adenain 
                EC 3.4.22.40                      bleomycin hydrolase 
                EC 3.4.22.41                      cathepsin F 
                EC 3.4.22.42                      cathepsin O 
                EC 3.4.22.43                      cathepsin V 
                EC 3.4.22.44                      nuclear-inclusion-a endopeptidase 
                EC 3.4.22.45                      helper-component proteinase 
                EC 3.4.22.46                      L-peptidase 
                EC 3.4.22.47                      gingipain K 
                EC 3.4.22.48                      staphopain 
                EC 3.4.22.49                      separase 
                EC 3.4.22.50                      V-cath endopeptidase 
                EC 3.4.22.51                      cruzipain 
                EC 3.4.22.52                      calpain-1 
                EC 3.4.22.53                      calpain-2 
                EC 3.4.22.54                      calpain-3 
                EC 3.4.22.55                      caspase-2 
                EC 3.4.22.56                      caspase-3 
                EC 3.4.22.57                      caspase-4 
                EC 3.4.22.58                      caspase-5 
                EC 3.4.22.59                      caspase-6 
                EC 3.4.22.60                      caspase-7 
                EC 3.4.22.61                      caspase-8 
                EC 3.4.22.62                      caspase-9 
                EC 3.4.22.63                      caspase-10 
                EC 3.4.22.64                      caspase-11 
                EC 3.4.22.65                      peptidase 1 (mite) 
                EC 3.4.22.66                      calicivirin 
                EC 3.4.22.67                      zingipain 
                EC 3.4.22.68                      Ulp1 peptidase 
                EC 3.4.22.69                      SARS coronavirus main proteinase 
                EC 3.4.22.70                      sortase A 
                EC 3.4.22.71                      sortase B 
        EC 3.4.23       []    Aspartic endopeptidases 
                EC 3.4.23.1                      pepsin A 
                EC 3.4.23.2                      pepsin B 
                EC 3.4.23.3                      gastricsin 
                EC 3.4.23.4                      chymosin 
                EC 3.4.23.5                      cathepsin D 
                EC 3.4.23.6                      now EC 3.4.23.30 pycnoporopepsin 
                EC 3.4.23.7                      Penicillium janthinellum acid proteinase. Now EC 3.4.23.20, penicillopepsin 
                EC 3.4.23.8                      yeast proteinase A. Now EC 3.4.23.25, saccharopepsin 
                EC 3.4.23.9                      Rhizopus acid proteinase. Now EC 3.4.23.21, rhizopuspepsin 
                EC 3.4.23.10                      Endothia acid proteinase. Now EC 3.4.23.22, endothiapepsin 
                EC 3.4.23.11                       thyroid aspartic proteinase 
                EC 3.4.23.12                      nepenthesin 
                EC 3.4.23.13                      Lotus aspartic proteinase 
                EC 3.4.23.14                       sorghum aspartic proteinase 
                EC 3.4.23.15                      renin 
                EC 3.4.23.16                      HIV-1 retropepsin 
                EC 3.4.23.17                      pro-opiomelanocortin converting enzyme 
                EC 3.4.23.18                      aspergillopepsin I 
                EC 3.4.23.19                      aspergillopepsin II 
                EC 3.4.23.20                      penicillopepsin 
                EC 3.4.23.21                      rhizopuspepsin 
                EC 3.4.23.22                      endothiapepsin 
                EC 3.4.23.23                      mucorpepsin 
                EC 3.4.23.24                      candidapepsin 
                EC 3.4.23.25                      saccharopepsin 
                EC 3.4.23.26                      rhodotorulapepsin 
                EC 3.4.23.27                      physaropepsin. Now EC 3.4.21.103, physarolisin 
                EC 3.4.23.28                      acrocylindropepsin 
                EC 3.4.23.29                      polyporopepsin 
                EC 3.4.23.30                      pycnoporopepsin 
                EC 3.4.23.31                      scytalidopepsin A 
                EC 3.4.23.32                      scytalidopepsin B 
                EC 3.4.23.33                      xanthomonapepsin. Now EC 3.4.21.101, xanthomonalisin 
                EC 3.4.23.34                      cathepsin E 
                EC 3.4.23.35                      barrierpepsin 
                EC 3.4.23.36                      signal peptidase II 
                EC 3.4.23.37                      pseudomonapepsin. Now EC 3.4.21.100, pseudomonalisin 
                EC 3.4.23.38                      plasmepsin I 
                EC 3.4.23.39                      plasmepsin II 
                EC 3.4.23.40                      phytepsin 
                EC 3.4.23.41                      yapsin 1 
                EC 3.4.23.42                      thermopsin 
                EC 3.4.23.43                      prepilin peptidase 
                EC 3.4.23.44                      nodavirus endopeptidase 
                EC 3.4.23.45                      memapsin 1 
                EC 3.4.23.46                      memapsin 2 
                EC 3.4.23.47                      HIV-2 retropepsin 
                EC 3.4.23.48                      plasminogen activator Pla 
                EC 3.4.23.49                      omptin 
                EC 3.4.23.50                      human endogenous retrovirus K endopeptidase 
                EC 3.4.23.51                      HycI peptidase 
                EC 3.4.23.52                      preflagellin peptidase 
        EC 3.4.24       []    Metalloendopeptidases 
                EC 3.4.24.1                      atrolysin A 
                EC 3.4.24.2                      Sepia proteinase 
                EC 3.4.24.3                      microbial collagenase 
                EC 3.4.24.4                      now EC 3.4.24.40 serralysin 
                EC 3.4.24.5                       lens neutral proteinase. Now included with EC 3.4.22.53 (calpain-2) and EC 3.4.25.1 (proteasome endopeptidase complex) 
                EC 3.4.24.6                      leucolysin 
                EC 3.4.24.7                      interstitial collagenase 
                EC 3.4.24.8                      Achromobacter iophagus collagenase. Now EC 3.4.24.3, microbial collagenase 
                EC 3.4.24.9                       Trichophyton schoenleinii collagenase 
                EC 3.4.24.10                      Trichophyton mentagrophytes keratinase 
                EC 3.4.24.11                      neprilysin 
                EC 3.4.24.12                      envelysin 
                EC 3.4.24.13                      IgA-specific metalloendopeptidase 
                EC 3.4.24.14                      procollagen N-endopeptidase 
                EC 3.4.24.15                      thimet oligopeptidase 
                EC 3.4.24.16                      neurolysin 
                EC 3.4.24.17                      stromelysin 1 
                EC 3.4.24.18                      meprin A 
                EC 3.4.24.19                      procollagen C-endopeptidase 
                EC 3.4.24.20                      peptidyl-Lys metalloendopeptidase 
                EC 3.4.24.21                      astacin 
                EC 3.4.24.22                      stromelysin 2 
                EC 3.4.24.23                      matrilysin 
                EC 3.4.24.24                      gelatinase A 
                EC 3.4.24.25                      vibriolysin 
                EC 3.4.24.26                      pseudolysin 
                EC 3.4.24.27                      thermolysin 
                EC 3.4.24.28                      bacillolysin 
                EC 3.4.24.29                      aureolysin 
                EC 3.4.24.30                      coccolysin 
                EC 3.4.24.31                      mycolysin 
                EC 3.4.24.32                      β-lytic metalloendopeptidase 
                EC 3.4.24.33                      peptidyl-Asp metalloendopeptidase 
                EC 3.4.24.34                      neutrophil collagenase 
                EC 3.4.24.35                      gelatinase B 
                EC 3.4.24.36                      leishmanolysin 
                EC 3.4.24.37                      saccharolysin 
                EC 3.4.24.38                      gametolysin 
                EC 3.4.24.39                      deuterolysin 
                EC 3.4.24.40                      serralysin 
                EC 3.4.24.41                      atrolysin B 
                EC 3.4.24.42                      atrolysin C 
                EC 3.4.24.43                      atroxase 
                EC 3.4.24.44                      atrolysin E 
                EC 3.4.24.45                      atrolysin F 
                EC 3.4.24.46                      adamalysin 
                EC 3.4.24.47                      horrilysin 
                EC 3.4.24.48                      ruberlysin 
                EC 3.4.24.49                      bothropasin 
                EC 3.4.24.50                      bothrolysin 
                EC 3.4.24.51                      ophiolysin 
                EC 3.4.24.52                      trimerelysin I 
                EC 3.4.24.53                      trimerelysin II 
                EC 3.4.24.54                      mucrolysin 
                EC 3.4.24.55                      pitrilysin 
                EC 3.4.24.56                      insulysin 
                EC 3.4.24.57                      O-sialoglycoprotein endopeptidase 
                EC 3.4.24.58                      russellysin 
                EC 3.4.24.59                      mitochondrial intermediate peptidase 
                EC 3.4.24.60                      dactylysin 
                EC 3.4.24.61                      nardilysin 
                EC 3.4.24.62                      magnolysin 
                EC 3.4.24.63                      meprin B 
                EC 3.4.24.64                      mitochondrial processing peptidase 
                EC 3.4.24.65                      macrophage elastase 
                EC 3.4.24.66                      choriolysin L 
                EC 3.4.24.67                      choriolysin H 
                EC 3.4.24.68                      tentoxilysin 
                EC 3.4.24.69                      bontoxilysin 
                EC 3.4.24.70                      oligopeptidase A 
                EC 3.4.24.71                      endothelin-converting enzyme 1 
                EC 3.4.24.72                      fibrolase 
                EC 3.4.24.73                      jararhagin 
                EC 3.4.24.74                      fragilysin 
                EC 3.4.24.75                      lysostaphin 
                EC 3.4.24.76                      flavastacin 
                EC 3.4.24.77                      snapalysin 
                EC 3.4.24.78                      gpr endopeptidase 
                EC 3.4.24.79                      pappalysin-1 
                EC 3.4.24.80                      membrane-type matrix metalloproteinase-1 
                EC 3.4.24.81                      ADAM10 endopeptidase 
                EC 3.4.24.82                      ADAMTS-4 endopeptidase 
                EC 3.4.24.83                      anthrax lethal factor endopeptidase 
                EC 3.4.24.84                      Ste24 endopeptidase 
                EC 3.4.24.85                      S2P endopeptidase 
                EC 3.4.24.86                      ADAM 17 endopeptidase 
                EC 3.4.24.87                      ADAMTS13 endopeptidase 
                EC 3.4.24.88                      desampylase. Transferred to EC 3.4.19.15 desampylase 
                EC 3.4.24.89                      Pro-Pro endopeptidase 
        EC 3.4.25       []    Threonine endopeptidases 
                EC 3.4.25.1                      proteasome endopeptidase complex 
                EC 3.4.25.2                      HslU—HslV peptidase 
        EC 3.4.26       []    Glutamic endopeptidases 
                EC 3.4.26.1                      intramembrane prenyl-peptidase Rce1 
                EC 3.4.26.2                      scytalidoglutamic peptidase 
        EC 3.4.99       []    Endopeptidases of unknown catalytic mechanism (sub-subclass is currently empty) 
                EC 3.4.99.1                      acrocylindricum proteinase. Now EC 3.4.23.28, acrocylindropepsin 
                EC 3.4.99.2                       agavain 
                EC 3.4.99.3                       angiotensinase 
                EC 3.4.99.4                      aspartylendopeptidase. Now EC 3.4.23.12, nepenthesin 
                EC 3.4.99.5                      Clostridium histolyticum collagenase 2. Now EC 3.4.24.3, microbial collagenase 
                EC 3.4.99.6                      crayfish low-molecular-weight proteinase. Now EC 3.4.24.21, astacin 
                EC 3.4.99.7                       euphorbain 
                EC 3.4.99.8                      Gliocladium proteinase 
                EC 3.4.99.9                      hurain. Now considered EC 3.4.21.25, cucumisin 
                EC 3.4.99.10                      insulinase. Now EC 3.4.24.56, insulysin 
                EC 3.4.99.11                      Streptomyces alkalophilic keratinase 
                EC 3.4.99.12                      Trichophyton mentagrophytes keratinase 
                EC 3.4.99.13                      β-lytic proteinase (Mycobacterium sorangium). Now EC 3.4.24.32, β-lytic metalloendopeptidase 
                EC 3.4.99.14                       mexicanain 
                EC 3.4.99.15                      Paecilomyces proteinase 
                EC 3.4.99.16                      Penicillium notatum extracellular proteinase 
                EC 3.4.99.17                       peptidoglycan endopeptidase 
                EC 3.4.99.18                       pinguinain 
                EC 3.4.99.19                      renin. Now EC 3.4.23.15, renin 
                EC 3.4.99.20                      Scopulariopsis proteinase 
                EC 3.4.99.21                      solanain. Now considered EC 3.4.21.25, cucumisin 
                EC 3.4.99.22                      staphylokinase. Now EC 3.4.24.29, aureolysin 
                EC 3.4.99.23                      tabernamontanain. Now considered EC 3.4.21.25, cucumisin 
                EC 3.4.99.24                      Tenebrio α-proteinase 
                EC 3.4.99.25                      trametes acid proteinase. Now EC 3.4.23.21, rhizopuspepsin 
                EC 3.4.99.26                      urokinase. Now EC 3.4.21.68, t-plasminogen activator 
                EC 3.4.99.27                      Echis carinatus prothrombin-activating proteinase 
                EC 3.4.99.28                      Oxyuranus scutellatus prothrombin-activating proteinase. Now EC 3.4.21.60, scutelarin 
                EC 3.4.99.29                      Myxobacter AL-1 proteinase I 
                EC 3.4.99.30                      Myxobacter AL-1 proteinase II. Now EC 3.4.24.20, peptidyl-Lys metalloendopeptidase 
                EC 3.4.99.31                      tissue endopeptidase degrading collagenase synthetic substrate. Now EC 3.4.24.15, thimet oligopeptidase 
                EC 3.4.99.32                      Armillaria mellea neutral proteinase. Now EC 3.4.24.20, peptidyl-Lys metalloendopeptidase 
                EC 3.4.99.33                       cathepsin R 
                EC 3.4.99.34                       mytilidase 
                EC 3.4.99.35                      premurein-leader peptidase. Now EC 3.4.23.36, signal peptidase II 
                EC 3.4.99.36                      leader peptidase. Now EC 3.4.21.89, signal peptidase I 
                EC 3.4.99.37                       RecA peptidase 
                EC 3.4.99.38                      pro-opiomelanotropin-converting proteinase. Now EC 3.4.23.17, pro-opiomelanocortin converting enzyme 
                EC 3.4.99.39                       pseudomurein endopeptidase 
                EC 3.4.99.40                       Pro-gonadoliberin proteinase 
                EC 3.4.99.41                      mitochondrial processing peptidase. Now EC 3.4.24.64, mitochondrial processing peptidase 
                EC 3.4.99.42                       leucyllysine endopeptidase 
                EC 3.4.99.43                      thermopsin. Now EC 3.4.23.42, thermopsin 
                EC 3.4.99.44                      pitrilysin. Now EC 3.4.24.55, pitrilysin 
                EC 3.4.99.45                      insulinase. Now EC 3.4.24.56, insulysin 
                EC 3.4.99.46                      multicatalytic endopeptidase complex. Now EC 3.4.25.1, proteasome endopeptidase complex 
    EC 3.5  [+]      
        EC 3.5.1       []    In linear amides 
                EC 3.5.1.1                      asparaginase 
                EC 3.5.1.2                      glutaminase 
                EC 3.5.1.3                      ω-amidase 
                EC 3.5.1.4                      amidase 
                EC 3.5.1.5                      urease 
                EC 3.5.1.6                      β-ureidopropionase 
                EC 3.5.1.7                      ureidosuccinase 
                EC 3.5.1.8                      formylaspartate deformylase 
                EC 3.5.1.9                      arylformamidase 
                EC 3.5.1.10                      formyltetrahydrofolate deformylase 
                EC 3.5.1.11                      penicillin amidase 
                EC 3.5.1.12                      biotinidase 
                EC 3.5.1.13                      aryl-acylamidase 
                EC 3.5.1.14                      N-acyl-aliphatic-L-amino acid amidohydrolase 
                EC 3.5.1.15                      aspartoacylase 
                EC 3.5.1.16                      acetylornithine deacetylase 
                EC 3.5.1.17                      acyl-lysine deacylase 
                EC 3.5.1.18                      succinyl-diaminopimelate desuccinylase 
                EC 3.5.1.19                      nicotinamidase 
                EC 3.5.1.20                      citrullinase 
                EC 3.5.1.21                      N-acetyl-β-alanine deacetylase 
                EC 3.5.1.22                      pantothenase 
                EC 3.5.1.23                      ceramidase 
                EC 3.5.1.24                      choloylglycine hydrolase 
                EC 3.5.1.25                      N-acetylglucosamine-6-phosphate deacetylase 
                EC 3.5.1.26                      N4-(β-N-acetylglucosaminyl)-L-asparaginase 
                EC 3.5.1.27                      N-formylmethionylaminoacyl-tRNA deformylase. The activity is covered by EC 3.5.1.88, peptide deformylase 
                EC 3.5.1.28                      N-acetylmuramoyl-L-alanine amidase 
                EC 3.5.1.29                      2-(acetamidomethylene)succinate hydrolase 
                EC 3.5.1.30                      5-aminopentanamidase 
                EC 3.5.1.31                      formylmethionine deformylase 
                EC 3.5.1.32                      hippurate hydrolase 
                EC 3.5.1.33                      N-acetylglucosamine deacetylase 
                EC 3.5.1.34                       acetylhistidine deacetylase. Identical with EC 3.4.13.5, Xaa-methyl-His dipeptidase 
                EC 3.5.1.35                      D-glutaminase 
                EC 3.5.1.36                      N-methyl-2-oxoglutaramate hydrolase 
                EC 3.5.1.37                       4-L-aspartylglycosylamine amidohydrolase. Identical with EC 3.5.1.26 N4-(β-N-acetylglucosaminyl)-L-asparaginase 
                EC 3.5.1.38                      glutamin-(asparagin-)ase 
                EC 3.5.1.39                      alkylamidase 
                EC 3.5.1.40                      acylagmatine amidase 
                EC 3.5.1.41                      chitin deacetylase 
                EC 3.5.1.42                      nicotinamide-nucleotide amidase 
                EC 3.5.1.43                      peptidyl-glutaminase 
                EC 3.5.1.44                      protein-glutamine glutaminase 
                EC 3.5.1.45                       urease (ATP-hydrolysing). Now listed only as EC 6.3.4.6 urea carboxylase 
                EC 3.5.1.46                      6-aminohexanoate-oligomer exohydrolase  
                EC 3.5.1.47                      N-acetyldiaminopimelate deacetylase 
                EC 3.5.1.48                      acetylspermidine deacetylase 
                EC 3.5.1.49                      formamidase 
                EC 3.5.1.50                      pentanamidase 
                EC 3.5.1.51                      4-acetamidobutyryl-CoA deacetylase 
                EC 3.5.1.52                      peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase 
                EC 3.5.1.53                      N-carbamoylputrescine amidase 
                EC 3.5.1.54                      allophanate hydrolase 
                EC 3.5.1.55                      long-chain-fatty-acyl-glutamate deacylase 
                EC 3.5.1.56                      N,N-dimethylformamidase 
                EC 3.5.1.57                      tryptophanamidase 
                EC 3.5.1.58                      N-benzyloxycarbonylglycine hydrolase 
                EC 3.5.1.59                      N-carbamoylsarcosine amidase 
                EC 3.5.1.60                      N-(long-chain-acyl)ethanolamine deacylase 
                EC 3.5.1.61                      mimosinase. Now EC 4.3.3.8, mimosinase 
                EC 3.5.1.62                      acetylputrescine deacetylase 
                EC 3.5.1.63                      4-acetamidobutyrate deacetylase 
                EC 3.5.1.64                      Nα-benzyloxycarbonylleucine hydrolase 
                EC 3.5.1.65                      theanine hydrolase 
                EC 3.5.1.66                      2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase 
                EC 3.5.1.67                      4-methyleneglutaminase 
                EC 3.5.1.68                      N-formylglutamate deformylase 
                EC 3.5.1.69                      glycosphingolipid deacylase 
                EC 3.5.1.70                      aculeacin-A deacylase 
                EC 3.5.1.71                      N-feruloylglycine deacylase 
                EC 3.5.1.72                      D-benzoylarginine-4-nitroanilide amidase 
                EC 3.5.1.73                      carnitinamidase 
                EC 3.5.1.74                      chenodeoxycholoyltaurine hydrolase 
                EC 3.5.1.75                      urethanase 
                EC 3.5.1.76                      arylalkyl acylamidase 
                EC 3.5.1.77                      N-carbamoyl-D-amino-acid hydrolase 
                EC 3.5.1.78                      glutathionylspermidine amidase 
                EC 3.5.1.79                      phthalyl amidase 
                EC 3.5.1.80                      N-acetylgalactosamine-6-phosphate deacetylase. Identical to EC 3.5.1.25, N-acetylglucosamine-6-phosphate deacetylase 
                EC 3.5.1.81                      N-acyl-D-amino-acid deacylase 
                EC 3.5.1.82                      N-acyl-D-glutamate deacylase 
                EC 3.5.1.83                      N-acyl-D-aspartate deacylase 
                EC 3.5.1.84                      biuret amidohydrolase 
                EC 3.5.1.85                      (S)-N-acetyl-1-phenylethylamine hydrolase 
                EC 3.5.1.86                      mandelamide amidase 
                EC 3.5.1.87                      N-carbamoyl-L-amino-acid hydrolase 
                EC 3.5.1.88                      peptide deformylase 
                EC 3.5.1.89                      N-acetylglucosaminylphosphatidylinositol deacetylase 
                EC 3.5.1.90                      adenosylcobinamide hydrolase 
                EC 3.5.1.91                      N-substituted formamide deformylase 
                EC 3.5.1.92                      pantetheine hydrolase 
                EC 3.5.1.93                      glutaryl-7-aminocephalosporanic-acid acylase 
                EC 3.5.1.94                      γ-glutamyl-γ-aminobutyrate hydrolase 
                EC 3.5.1.95                      N-malonylurea hydrolase 
                EC 3.5.1.96                      succinylglutamate desuccinylase 
                EC 3.5.1.97                      acyl-homoserine-lactone acylase 
                EC 3.5.1.98                      histone deacetylase 
                EC 3.5.1.99                      fatty acid amide hydrolase 
                EC 3.5.1.100                      (R)-amidase 
                EC 3.5.1.101                      L-proline amide hydrolase 
                EC 3.5.1.102                      2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase 
                EC 3.5.1.103                      N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase 
                EC 3.5.1.104                      peptidoglycan-N-acetylglucosamine deacetylase 
                EC 3.5.1.105                      chitin disaccharide deacetylase 
                EC 3.5.1.106                      N-formylmaleamate deformylase 
                EC 3.5.1.107                      maleamate amidohydrolase 
                EC 3.5.1.108                      UDP-3-O-acyl-N-acetylglucosamine deacetylase 
                EC 3.5.1.109                      sphingomyelin deacylase 
                EC 3.5.1.110                      ureidoacrylate amidohydrolase 
                EC 3.5.1.111                      2-oxoglutaramate amidase 
                EC 3.5.1.112                      2′-N-acetylparomamine deacetylase 
                EC 3.5.1.113                      2′′′-acetyl-6′′′-hydroxyneomycin C deacetylase 
                EC 3.5.1.114                      N-acyl-aromatic-L-amino acid amidohydrolase 
                EC 3.5.1.115                      mycothiol S-conjugate amidase 
                EC 3.5.1.116                      ureidoglycolate amidohydrolase 
                EC 3.5.1.117                      6-aminohexanoate-oligomer endohydrolase  
                EC 3.5.1.118                      γ-glutamyl hercynylcysteine S-oxide hydrolase 
                EC 3.5.1.119                      Pup amidohydrolase 
                EC 3.5.1.120                      2-aminomuconate deaminase (2-hydroxymuconate-forming). Now EC 3.5.99.11, 2-aminomuconate deaminase (2-hydroxymuconate-forming)  
                EC 3.5.1.121                      protein N-terminal asparagine amidohydrolase 
                EC 3.5.1.122                      protein N-terminal glutamine amidohydrolase 
                EC 3.5.1.123                      γ-glutamylanilide hydrolase 
                EC 3.5.1.124                      protein deglycase 
                EC 3.5.1.125                      N2-acetyl-L-2,4-diaminobutanoate deacetylase 
                EC 3.5.1.126                      oxamate amidohydrolase 
                EC 3.5.1.127                      jasmonoyl-L-amino acid hydrolase 
                EC 3.5.1.128                      deaminated glutathione amidase 
                EC 3.5.1.129                      N5-(cytidine 5′-diphosphoramidyl)-L-glutamine hydrolase 
                EC 3.5.1.130                      [amino group carrier protein]-lysine hydrolase 
                EC 3.5.1.131                      1-carboxybiuret hydrolase 
                EC 3.5.1.132                      [amino group carrier protein]-ornithine hydrolase 
                EC 3.5.1.133                      Nα-acyl-L-glutamine aminoacylase 
                EC 3.5.1.134                      (indol-3-yl)acetyl-L-aspartate hydrolase 
                EC 3.5.1.135                      N4-acetylcytidine amidohydrolase 
                EC 3.5.1.136                      N,N′-diacetylchitobiose non-reducing end deacetylase 
                EC 3.5.1.137                      N-methylcarbamate hydrolase 
                EC 3.5.1.138                      lipoamidase 
        EC 3.5.2       []    In cyclic amides 
                EC 3.5.2.1                      barbiturase 
                EC 3.5.2.2                      dihydropyrimidinase 
                EC 3.5.2.3                      dihydroorotase 
                EC 3.5.2.4                      carboxymethylhydantoinase 
                EC 3.5.2.5                      allantoinase 
                EC 3.5.2.6                      β-lactamase 
                EC 3.5.2.7                      imidazolonepropionase 
                EC 3.5.2.8                       cephalosporinase. Now included with EC 3.5.2.6 β-lactamase 
                EC 3.5.2.9                      5-oxoprolinase (ATP-hydrolysing) 
                EC 3.5.2.10                      creatininase 
                EC 3.5.2.11                      L-lysine-lactamase 
                EC 3.5.2.12                      6-aminohexanoate-cyclic-dimer hydrolase 
                EC 3.5.2.13                      2,5-dioxopiperazine hydrolase 
                EC 3.5.2.14                      N-methylhydantoinase (ATP-hydrolysing) 
                EC 3.5.2.15                      cyanuric acid amidohydrolase 
                EC 3.5.2.16                      maleimide hydrolase 
                EC 3.5.2.17                      hydroxyisourate hydrolase 
                EC 3.5.2.18                      enamidase 
                EC 3.5.2.19                      streptothricin hydrolase 
                EC 3.5.2.20                      isatin hydrolase 
        EC 3.5.3       []    In linear amidines 
                EC 3.5.3.1                      arginase 
                EC 3.5.3.2                      guanidinoacetase 
                EC 3.5.3.3                      creatinase 
                EC 3.5.3.4                      allantoicase 
                EC 3.5.3.5                      formimidoylaspartate deiminase 
                EC 3.5.3.6                      arginine deiminase 
                EC 3.5.3.7                      guanidinobutyrase 
                EC 3.5.3.8                      formimidoylglutamase 
                EC 3.5.3.9                      allantoate deiminase 
                EC 3.5.3.10                      D-arginase 
                EC 3.5.3.11                      agmatinase 
                EC 3.5.3.12                      agmatine deiminase 
                EC 3.5.3.13                      formimidoylglutamate deiminase 
                EC 3.5.3.14                      amidinoaspartase 
                EC 3.5.3.15                      protein-arginine deiminase 
                EC 3.5.3.16                      methylguanidinase 
                EC 3.5.3.17                      guanidinopropionase 
                EC 3.5.3.18                      dimethylargininase 
                EC 3.5.3.19                      ureidoglycolate hydrolase. Now EC 3.5.1.116, ureidoglycolate amidohydrolase 
                EC 3.5.3.20                      diguanidinobutanase 
                EC 3.5.3.21                      methylenediurea deaminase 
                EC 3.5.3.22                      proclavaminate amidinohydrolase 
                EC 3.5.3.23                      N-succinylarginine dihydrolase 
                EC 3.5.3.24                      N1-aminopropylagmatine ureohydrolase 
                EC 3.5.3.25                      Nω-hydroxy-L-arginine amidinohydrolase 
                EC 3.5.3.26                      (S)-ureidoglycine aminohydrolase 
        EC 3.5.4       []    In cyclic amidines 
                EC 3.5.4.1                      cytosine deaminase 
                EC 3.5.4.2                      adenine deaminase 
                EC 3.5.4.3                      guanine deaminase 
                EC 3.5.4.4                      adenosine deaminase 
                EC 3.5.4.5                      cytidine deaminase 
                EC 3.5.4.6                      AMP deaminase 
                EC 3.5.4.7                      ADP deaminase 
                EC 3.5.4.8                      aminoimidazolase 
                EC 3.5.4.9                      methenyltetrahydrofolate cyclohydrolase 
                EC 3.5.4.10                      IMP cyclohydrolase 
                EC 3.5.4.11                      pterin deaminase 
                EC 3.5.4.12                      dCMP deaminase 
                EC 3.5.4.13                      dCTP deaminase 
                EC 3.5.4.14                      deoxycytidine deaminase. Now included in EC 3.5.4.5, (deoxy)cytidine deaminase 
                EC 3.5.4.15                      guanosine deaminase 
                EC 3.5.4.16                      GTP cyclohydrolase I 
                EC 3.5.4.17                      adenosine-phosphate deaminase 
                EC 3.5.4.18                      ATP deaminase 
                EC 3.5.4.19                      phosphoribosyl-AMP cyclohydrolase 
                EC 3.5.4.20                      pyrithiamine deaminase 
                EC 3.5.4.21                      creatinine deaminase 
                EC 3.5.4.22                      1-pyrroline-4-hydroxy-2-carboxylate deaminase 
                EC 3.5.4.23                      blasticidin-S deaminase 
                EC 3.5.4.24                      sepiapterin deaminase 
                EC 3.5.4.25                      GTP cyclohydrolase II 
                EC 3.5.4.26                      diaminohydroxyphosphoribosylaminopyrimidine deaminase 
                EC 3.5.4.27                      methenyltetrahydromethanopterin cyclohydrolase 
                EC 3.5.4.28                      S-adenosylhomocysteine deaminase 
                EC 3.5.4.29                      GTP cyclohydrolase IIa 
                EC 3.5.4.30                      dCTP deaminase (dUMP-forming) 
                EC 3.5.4.31                      S-methyl-5′-thioadenosine deaminase 
                EC 3.5.4.32                      8-oxoguanine deaminase 
                EC 3.5.4.33                      tRNA(adenine34) deaminase 
                EC 3.5.4.34                      tRNAAla(adenine37) deaminase 
                EC 3.5.4.35                      tRNA(cytosine8) deaminase 
                EC 3.5.4.36                      mRNA(cytosine6666) deaminase 
                EC 3.5.4.37                      double-stranded RNA adenine deaminase 
                EC 3.5.4.38                      single-stranded DNA cytosine deaminase 
                EC 3.5.4.39                      GTP cyclohydrolase IV 
                EC 3.5.4.40                      aminodeoxyfutalosine deaminase 
                EC 3.5.4.41                      5′-deoxyadenosine deaminase 
                EC 3.5.4.42                      N-isopropylammelide isopropylaminohydrolase 
                EC 3.5.4.43                      hydroxydechloroatrazine ethylaminohydrolase 
                EC 3.5.4.44                      ectoine hydrolase 
                EC 3.5.4.45                      melamine deaminase 
                EC 3.5.4.46                      cAMP deaminase 
        EC 3.5.5       []    In nitriles 
                EC 3.5.5.1                      nitrilase 
                EC 3.5.5.2                      ricinine nitrilase 
                EC 3.5.5.3                      cyanate hydrolase. Now EC 4.2.1.104, cyanate hydratase 
                EC 3.5.5.4                      cyanoalanine nitrilase 
                EC 3.5.5.5                      arylacetonitrilase 
                EC 3.5.5.6                      bromoxynil nitrilase 
                EC 3.5.5.7                      aliphatic nitrilase 
                EC 3.5.5.8                      thiocyanate hydrolase 
        EC 3.5.99       []    In other compounds 
                EC 3.5.99.1                      riboflavinase 
                EC 3.5.99.2                      aminopyrimidine aminohydrolase 
                EC 3.5.99.3                      hydroxydechloroatrazine ethylaminohydrolase. Now EC 3.5.4.43, hydroxydechloroatrazine ethylaminohydrolase 
                EC 3.5.99.4                      N-isopropylammelide isopropylaminohydrolase. Now EC 3.5.4.42, N-isopropylammelide isopropylaminohydrolase 
                EC 3.5.99.5                      2-aminomuconate deaminase 
                EC 3.5.99.6                      glucosamine-6-phosphate deaminase 
                EC 3.5.99.7                      1-aminocyclopropane-1-carboxylate deaminase 
                EC 3.5.99.8                      5-nitroanthranilic acid aminohydrolase 
                EC 3.5.99.9                      2-nitroimidazole nitrohydrolase 
                EC 3.5.99.10                      2-iminobutanoate/2-iminopropanoate deaminase 
                EC 3.5.99.11                      2-aminomuconate deaminase (2-hydroxymuconate-forming) 
    EC 3.6  [+]      
        EC 3.6.1       []    In phosphorus-containing anhydrides 
                EC 3.6.1.1                      inorganic diphosphatase 
                EC 3.6.1.2                      trimetaphosphatase 
                EC 3.6.1.3                      adenosinetriphosphatase. Enzymes previously listed under this number are now listed separately under EC 5.6 and EC 7. 
                EC 3.6.1.4                       adenosinetriphosphatase (Mg-activated). Now included with EC 3.6.1.3 adenosinetriphosphatase 
                EC 3.6.1.5                      apyrase 
                EC 3.6.1.6                      nucleoside diphosphate phosphatase 
                EC 3.6.1.7                      acylphosphatase 
                EC 3.6.1.8                      ATP diphosphatase 
                EC 3.6.1.9                      nucleotide diphosphatase 
                EC 3.6.1.10                      endopolyphosphatase 
                EC 3.6.1.11                      exopolyphosphatase 
                EC 3.6.1.12                      dCTP diphosphatase 
                EC 3.6.1.13                      ADP-ribose diphosphatase 
                EC 3.6.1.14                      adenosine-tetraphosphatase 
                EC 3.6.1.15                      nucleoside-triphosphate phosphatase 
                EC 3.6.1.16                      CDP-glycerol diphosphatase 
                EC 3.6.1.17                      bis(5′-nucleosyl)-tetraphosphatase (asymmetrical) 
                EC 3.6.1.18                      FAD diphosphatase 
                EC 3.6.1.19                      nucleoside-triphosphate diphosphatase. Now EC 3.6.1.9, nucleotide diphosphatase 
                EC 3.6.1.20                      5′-acylphosphoadenosine hydrolase 
                EC 3.6.1.21                      ADP-sugar diphosphatase 
                EC 3.6.1.22                      NAD+ diphosphatase 
                EC 3.6.1.23                      dUTP diphosphatase 
                EC 3.6.1.24                      nucleoside phosphoacylhydrolase 
                EC 3.6.1.25                      triphosphatase 
                EC 3.6.1.26                      CDP-diacylglycerol diphosphatase 
                EC 3.6.1.27                      undecaprenyl-diphosphate phosphatase 
                EC 3.6.1.28                      thiamine-triphosphatase 
                EC 3.6.1.29                      bis(5′-adenosyl)-triphosphatase 
                EC 3.6.1.30                      m7G(5′)pppN diphosphatase. Now covered by EC 3.6.1.59 [m7GpppX diphosphatase] and EC 3.6.1.62 [m7GpppN-mRNA hydrolase]. 
                EC 3.6.1.31                      phosphoribosyl-ATP diphosphatase 
                EC 3.6.1.32                      myosin ATPase. Now EC 3.6.4.1, myosin ATPase 
                EC 3.6.1.33                      dynein ATPase. Now EC 3.6.4.2, dynein ATPase 
                EC 3.6.1.34                      H+-transporting ATP synthase. Now EC 3.6.3.14, H+-transporting two-sector ATPase 
                EC 3.6.1.35                      H+-transporting ATPase. Now EC 3.6.3.6, H+-exporting ATPase 
                EC 3.6.1.36                      H+/K+ exchanging ATPase. Now EC 3.6.3.10, H+/K+-exchanging ATPase 
                EC 3.6.1.37                      Na+/K+ exchanging ATPase. Now EC 3.6.3.9, Na+/K+-exchanging ATPase 
                EC 3.6.1.38                      Ca2+-transporting ATPase. Now EC 3.6.3.8, Ca2+-transporting ATPase 
                EC 3.6.1.39                      thymidine-triphosphatase 
                EC 3.6.1.40                      guanosine-5′-triphosphate,3′-diphosphate phosphatase 
                EC 3.6.1.41                      bis(5′-nucleosyl)-tetraphosphatase (symmetrical) 
                EC 3.6.1.42                      guanosine-diphosphatase 
                EC 3.6.1.43                      dolichyldiphosphatase 
                EC 3.6.1.44                      oligosaccharide-diphosphodolichol diphosphatase 
                EC 3.6.1.45                      UDP-sugar diphosphatase 
                EC 3.6.1.46                      heterotrimeric G-protein GTPase. Now EC 3.6.5.1, heterotrimeric G-protein GTPase 
                EC 3.6.1.47                      small monomeric GTPase. Now EC 3.6.5.2, small monomeric GTPase 
                EC 3.6.1.48                      protein-synthesizing GTPase. Now EC 3.6.5.3, protein-synthesizing GTPase 
                EC 3.6.1.49                      signal-recognition-particle GTPase. Now EC 3.6.5.4, signal-recognition-particle GTPase 
                EC 3.6.1.50                      dynamin GTPase. Now EC 3.6.5.5, dynamin GTPase 
                EC 3.6.1.51                      tubulin GTPase. Now EC 3.6.5.6, tubulin GTPase 
                EC 3.6.1.52                      diphosphoinositol-polyphosphate diphosphatase 
                EC 3.6.1.53                      Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase 
                EC 3.6.1.54                      UDP-2,3-diacylglucosamine diphosphatase 
                EC 3.6.1.55                      8-oxo-dGTP diphosphatase 
                EC 3.6.1.56                      2-hydroxy-dATP diphosphatase 
                EC 3.6.1.57                      UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase 
                EC 3.6.1.58                      8-oxo-dGDP phosphatase 
                EC 3.6.1.59                      5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase 
                EC 3.6.1.60                      diadenosine hexaphosphate hydrolase (AMP-forming) 
                EC 3.6.1.61                      diadenosine hexaphosphate hydrolase (ATP-forming) 
                EC 3.6.1.62                      5′-(N7-methylguanosine 5′-triphospho)-[mRNA] hydrolase 
                EC 3.6.1.63                      α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase 
                EC 3.6.1.64                      inosine diphosphate phosphatase 
                EC 3.6.1.65                      (d)CTP diphosphatase 
                EC 3.6.1.66                      XTP/dITP diphosphatase 
                EC 3.6.1.67                      dihydroneopterin triphosphate diphosphatase 
                EC 3.6.1.68                      geranyl diphosphate phosphohydrolase 
                EC 3.6.1.69                      8-oxo-(d)GTP phosphatase 
                EC 3.6.1.70                      guanosine-5′-diphospho-5′-[DNA] diphosphatase 
                EC 3.6.1.71                      adenosine-5′-diphospho-5′-[DNA] diphosphatase 
                EC 3.6.1.72                      DNA-3′-diphospho-5′-guanosine diphosphatase 
                EC 3.6.1.73                      inosine/xanthosine triphosphatase 
                EC 3.6.1.74                      mRNA 5′-phosphatase 
                EC 3.6.1.75                      diacylglycerol diphosphate phosphatase 
                EC 3.6.1.76                      prenyl-diphosphate phosphatase 
        EC 3.6.2       []    In sulfonyl-containing anhydrides 
                EC 3.6.2.1                      adenylylsulfatase 
                EC 3.6.2.2                      phosphoadenylylsulfatase 
        EC 3.6.3       []      
                EC 3.6.3.1                      phospholipid-translocating ATPase. Now EC 7.6.2.1, P-type phospholipid transporter 
                EC 3.6.3.2                      Mg2+-importing ATPase. Now EC 7.2.2.14, P-type Mg2+ transporter 
                EC 3.6.3.3                      Cd2+-exporting ATPase. Now EC 7.2.2.21, Cd2+-exporting ATPase 
                EC 3.6.3.4                      Cu2+-exporting ATPase. Now EC 7.2.2.9, Cu2+-exporting ATPase 
                EC 3.6.3.5                      Zn2+-exporting ATPase. Now EC 7.2.2.12, Zn2+-exporting ATPase 
                EC 3.6.3.6                      H+-exporting ATPase. Now EC 7.1.2.1, P-type H+-exporting transporter 
                EC 3.6.3.7                      Na+-exporting ATPase. Now EC 7.2.2.3, P-type Na+ transporter 
                EC 3.6.3.8                      Ca2+-transporting ATPase. Now EC 7.2.2.10, Ca2+-transporting ATPase 
                EC 3.6.3.9                      Na+/K+-exchanging ATPase. Now EC 7.2.2.13, Na+/K+-exchanging ATPase  
                EC 3.6.3.10                      H+/K+-exchanging ATPase. Now EC 7.2.2.19, H+/K+-exchanging ATPase 
                EC 3.6.3.11                      Cl--transporting ATPase. The activity was only ever studied in crude extracts, and is an artifact. 
                EC 3.6.3.12                      K+-transporting ATPase. Now EC 7.2.2.6, K+-transporting ATPase 
                EC 3.6.3.13                      aminophospholipid-transporting ATPase. Identical to EC 3.6.3.1, phospholipid-translocating ATPase 
                EC 3.6.3.14                      H+-transporting two-sector ATPase. Now EC 7.1.2.2, H+-transporting two-sector ATPase 
                EC 3.6.3.15                      Na+-transporting two-sector ATPase. Now EC 7.2.2.1, Na+-transporting two-sector ATPase 
                EC 3.6.3.16                      arsenite-transporting ATPase. Now EC 7.3.2.7, arsenite-transporting ATPase 
                EC 3.6.3.17                      monosaccharide-transporting ATPase. Now covered by various ABC-type monosaccharide transporters in sub-subclass EC 7.5.2. 
                EC 3.6.3.18                      oligosaccharide-transporting ATPase. Now EC 7.5.2.2, ABC-type oligosaccharide transporter 
                EC 3.6.3.19                      maltose-transporting ATPase. Now EC 7.5.2.1, ABC-type maltose transporter 
                EC 3.6.3.20                      glycerol-3-phosphate-transporting ATPase. Now EC 7.6.2.10, glycerol-3-phosphate-transporting ATPase 
                EC 3.6.3.21                      polar-amino-acid-transporting ATPase. Now EC 7.4.2.1, ABC-type polar-amino-acid transporter 
                EC 3.6.3.22                      nonpolar-amino-acid-transporting ATPase. Now EC 7.4.2.2, ABC-type nonpolar-amino-acid transporter 
                EC 3.6.3.23                      oligopeptide-transporting ATPase. Now EC 7.4.2.6, oligopeptide-transporting ATPase 
                EC 3.6.3.24                      nickel-transporting ATPase. Now EC 7.2.2.11, nickel-transporting ATPase 
                EC 3.6.3.25                      sulfate-transporting ATPase. Now EC 7.3.2.3, sulfate-transporting ATPase 
                EC 3.6.3.26                      nitrate-transporting ATPase. Now EC 7.3.2.4, nitrate-transporting ATPase 
                EC 3.6.3.27                      phosphate-transporting ATPase. Now EC 7.3.2.1, ABC-type phosphate transporter  
                EC 3.6.3.28                      phosphonate-transporting ATPase. Now EC 7.3.2.2, ABC-type phosphonate transporter 
                EC 3.6.3.29                      molybdate-transporting ATPase. Now EC 7.3.2.5, molybdate-transporting ATPase 
                EC 3.6.3.30                      Fe3+-transporting ATPase. Now EC 7.2.2.7, Fe3+-transporting ATPase 
                EC 3.6.3.31                      polyamine-transporting ATPase. Now EC 7.6.2.11, polyamine-transporting ATPase 
                EC 3.6.3.32                      quaternary-amine-transporting ATPase. Now EC 7.6.2.9, quaternary-amine-transporting ATPase 
                EC 3.6.3.33                      vitamin B12-transporting ATPase. Now EC 7.6.2.8, vitamin B12-transporting ATPase 
                EC 3.6.3.34                      iron-chelate-transporting ATPase; now recognized to be at least 3 separate enzymes EC 7.2.2.16, iron(III) hydroxamate ABC transporter, EC 7.2.2.17, ferric enterobactin ABC transporter, and EC 7.2.2.18, ferric citrate ABC transporter 
                EC 3.6.3.35                      manganese-transporting ATPase. Now EC 7.2.2.5, manganese-transporting ATPase 
                EC 3.6.3.36                      taurine-transporting ATPase. Now EC 7.6.2.7, taurine-transporting ATPase 
                EC 3.6.3.37                      guanine-transporting ATPase. Now EC 7.6.2.6, guanine-transporting ATPase 
                EC 3.6.3.38                      capsular-polysaccharide-transporting ATPase. Now EC 7.6.2.12, ABC-type capsular-polysaccharide transporter 
                EC 3.6.3.39                      lipopolysaccharide-transporting ATPase. Now EC 7.5.2.5, lipopolysaccharide-transporting ATPase 
                EC 3.6.3.40                      teichoic-acid-transporting ATPase. Now EC 7.5.2.4, teichoic-acid-transporting ATPase 
                EC 3.6.3.41                      heme-transporting ATPase. Now EC 7.6.2.5, heme-transporting ATPase 
                EC 3.6.3.42                      β-glucan-transporting ATPase. Now EC 7.5.2.3, β-glucan-transporting ATPase 
                EC 3.6.3.43                      peptide-transporting ATPase. Now EC 7.4.2.5, peptide-transporting ATPase 
                EC 3.6.3.44                      xenobiotic-transporting ATPase. Now EC 7.6.2.2, ABC-type xenobiotic transporter 
                EC 3.6.3.45                      steroid-transporting ATPase. Now included with EC 3.6.3.44, xenobiotic-transporting ATPase 
                EC 3.6.3.46                      cadmium-transporting ATPase. Now EC 7.2.2.2, ABC-type Cd2+ transporter 
                EC 3.6.3.47                      fatty-acyl-CoA-transporting ATPase. Now EC 7.6.2.4, fatty-acyl-CoA-transporting ATPase 
                EC 3.6.3.48                      α-factor-transporting ATPase. Now EC 7.4.2.7 as α-factor-pheromone transporting ATPase 
                EC 3.6.3.49                      channel-conductance-controlling ATPase. Now EC 5.6.1.6, channel-conductance-controlling ATPase 
                EC 3.6.3.50                      protein-secreting ATPase. Now EC 7.4.2.8, protein-secreting ATPase 
                EC 3.6.3.51                      mitochondrial protein-transporting ATPase. Now EC 7.4.2.3, mitochondrial protein-transporting ATPase 
                EC 3.6.3.52                      chloroplast protein-transporting ATPase. Now EC 7.4.2.4, chloroplast protein-transporting ATPase 
                EC 3.6.3.53                      Ag+-exporting ATPase. Now EC 7.2.2.15, Ag+-exporting ATPase 
                EC 3.6.3.54                      Cu+-exporting ATPase. Now EC 7.2.2.8, Cu+-exporting ATPase 
                EC 3.6.3.55                      tungstate-importing ATPase. Now EC 7.3.2.6, tungstate-importing ATPase 
        EC 3.6.4       []    Acting on acid anhydrides to facilitate cellular and subcellular movement 
                EC 3.6.4.1                      myosin ATPase. Now EC 5.6.1.8, myosin ATPase 
                EC 3.6.4.2                      dynein ATPase. Now EC 5.6.1.2, dynein ATPase 
                EC 3.6.4.3                      microtubule-severing ATPase. Now EC 5.6.1.1, microtubule-severing ATPase 
                EC 3.6.4.4                      plus-end-directed kinesin ATPase. Now EC 5.6.1.3, plus-end-directed kinesin ATPase 
                EC 3.6.4.5                      minus-end-directed kinesin ATPase. Now EC 5.6.1.4, minus-end-directed kinesin ATPase 
                EC 3.6.4.6                      vesicle-fusing ATPase 
                EC 3.6.4.7                      peroxisome-assembly ATPase 
                EC 3.6.4.8                      proteasome ATPase. Now EC 5.6.1.5, proteasome ATPase 
                EC 3.6.4.9                      chaperonin ATPase. Now EC 5.6.1.7, chaperonin ATPase 
                EC 3.6.4.10                      non-chaperonin molecular chaperone ATPase 
                EC 3.6.4.11                      nucleoplasmin ATPase. The activity has been shown not to take place. 
                EC 3.6.4.12                      DNA helicase. Now EC 5.6.2.3, DNA 5′-3′ helicase and EC 5.6.2.4, DNA 3′-5′ helicase 
                EC 3.6.4.13                      RNA helicase 
        EC 3.6.5       []    Acting on GTP to facilitate cellular and subcellular movement 
                EC 3.6.5.1                      heterotrimeric G-protein GTPase 
                EC 3.6.5.2                      small monomeric GTPase 
                EC 3.6.5.3                      protein-synthesizing GTPase 
                EC 3.6.5.4                      signal-recognition-particle GTPase 
                EC 3.6.5.5                      dynamin GTPase 
                EC 3.6.5.6                      tubulin GTPase 
    EC 3.7  [+]      
        EC 3.7.1       []    In ketonic substances 
                EC 3.7.1.1                      oxaloacetase 
                EC 3.7.1.2                      fumarylacetoacetase 
                EC 3.7.1.3                      kynureninase 
                EC 3.7.1.4                      phloretin hydrolase 
                EC 3.7.1.5                      acylpyruvate hydrolase 
                EC 3.7.1.6                      acetylpyruvate hydrolase 
                EC 3.7.1.7                      β-diketone hydrolase 
                EC 3.7.1.8                      2,6-dioxo-6-phenylhexa-3-enoate hydrolase 
                EC 3.7.1.9                      2-hydroxymuconate-6-semialdehyde hydrolase 
                EC 3.7.1.10                      cyclohexane-1,3-dione hydrolase 
                EC 3.7.1.11                      cyclohexane-1,2-dione hydrolase 
                EC 3.7.1.12                      cobalt-precorrin 5A hydrolase 
                EC 3.7.1.13                      2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase 
                EC 3.7.1.14                      2-hydroxy-6-oxonona-2,4-dienedioate hydrolase 
                EC 3.7.1.15                      (+)-caryolan-1-ol synthase. Now EC 4.2.1.138, (+)-caryolan-1-ol synthase 
                EC 3.7.1.16                      oxepin-CoA hydrolase. Now EC 3.3.2.12, oxepin-CoA hydrolase 
                EC 3.7.1.17                      4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase 
                EC 3.7.1.18                      6-oxocamphor hydrolase 
                EC 3.7.1.19                      2,6-dihydroxypseudooxynicotine hydrolase 
                EC 3.7.1.20                      3-fumarylpyruvate hydrolase 
                EC 3.7.1.21                      6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase 
                EC 3.7.1.22                      3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) 
                EC 3.7.1.23                      maleylpyruvate hydrolase 
                EC 3.7.1.24                      2,4-diacetylphloroglucinol hydrolase 
                EC 3.7.1.25                      2-hydroxy-6-oxohepta-2,4-dienoate hydrolase 
                EC 3.7.1.26                      2,4-didehydro-3-deoxy-L-rhamnonate hydrolase 
                EC 3.7.1.27                      neryl diphosphate diphosphatase. Now EC 3.1.7.13, neryl diphosphate diphosphatase. 
                EC 3.7.1.28                      3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase 
    EC 3.8  [+]      
        EC 3.8.1       []    In carbon-halide compounds 
                EC 3.8.1.1                      alkylhalidase. Covered by EC 3.8.1.5, haloalkane dehalogenase. 
                EC 3.8.1.2                      (S)-2-haloacid dehalogenase 
                EC 3.8.1.3                      haloacetate dehalogenase 
                EC 3.8.1.4                      thyroxine deiodinase. Now EC 1.97.1.10, thyroxine 5′-deiodinase 
                EC 3.8.1.5                      haloalkane dehalogenase 
                EC 3.8.1.6                      4-chlorobenzoate dehalogenase 
                EC 3.8.1.7                      4-chlorobenzoyl-CoA dehalogenase 
                EC 3.8.1.8                      atrazine chlorohydrolase 
                EC 3.8.1.9                      (R)-2-haloacid dehalogenase 
                EC 3.8.1.10                      2-haloacid dehalogenase (configuration-inverting) 
                EC 3.8.1.11                      2-haloacid dehalogenase (configuration-retaining) 
        EC 3.8.2       []    In phosphorus-halide compounds 
                EC 3.8.2.1                      di-isopropyl-fluorophosphatase. Now EC 3.1.8.2, diisopropyl-fluorophosphatase 
                EC 3.8.2.2                      diisopropyl-fluorophosphatase 
    EC 3.9  [+]      
        EC 3.9.1       []    Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date) 
                EC 3.9.1.1                      phosphoamidase 
                EC 3.9.1.2                      protein arginine phosphatase 
                EC 3.9.1.3                      phosphohistidine phosphatase 
    EC 3.10  [+]      
        EC 3.10.1       []    Acting on sulfur-nitrogen bonds (only sub-subclass identified to date) 
                EC 3.10.1.1                      N-sulfoglucosamine sulfohydrolase 
                EC 3.10.1.2                      cyclamate sulfohydrolase 
    EC 3.11  [+]      
        EC 3.11.1       []    Acting on carbon-phosphorus bonds (only sub-subclass identified to date) 
                EC 3.11.1.1                      phosphonoacetaldehyde hydrolase 
                EC 3.11.1.2                      phosphonoacetate hydrolase 
                EC 3.11.1.3                      phosphonopyruvate hydrolase 
    EC 3.12  [+]      
        EC 3.12.1       []    Acting on sulfur-sulfur bonds (only sub-subclass identified to date) 
                EC 3.12.1.1                      trithionate hydrolase 
    EC 3.13  [+]      
        EC 3.13.1       []    Acting on carbon-sulfur bonds 
                EC 3.13.1.1                      UDP-sulfoquinovose synthase 
                EC 3.13.1.2                       5-deoxyribos-5-ylhomocysteinase. The activity is most probably attributable to EC 4.4.1.21, S-ribosylhomocysteine lyase 
                EC 3.13.1.3                      2′-hydroxybiphenyl-2-sulfinate desulfinase 
                EC 3.13.1.4                      3-sulfinopropanoyl-CoA desulfinase 
                EC 3.13.1.5                      carbon disulfide hydrolase 
                EC 3.13.1.6                      [CysO sulfur-carrier protein]-S-L-cysteine hydrolase 
                EC 3.13.1.7                      carbonyl sulfide hydrolase 
                EC 3.13.1.8                      S-adenosyl-L-methionine hydrolase (adenosine-forming), now classified as EC 3.13.2.3, S-adenosyl-L-methionine hydrolase (adenosine-forming) 
                EC 3.13.1.9                      S-inosyl-L-homocysteine hydrolase 
        EC 3.13.2       []    Thioether and trialkylsulfonium hydrolases 
                EC 3.13.2.1                      adenosylhomocysteinase 
                EC 3.13.2.2                      S-adenosyl-L-methionine hydrolase (L-homoserine-forming). Now classified as EC 4.4.1.42, S-adenosyl-L-methionine lyase 
                EC 3.13.2.3                      (R)-S-adenosyl-L-methionine hydrolase (adenosine-forming) 
EC 4 [+]   
    EC 4.1  [+]      
        EC 4.1.1       []    Carboxy-lyases 
                EC 4.1.1.1                      pyruvate decarboxylase 
                EC 4.1.1.2                      oxalate decarboxylase 
                EC 4.1.1.3                      oxaloacetate decarboxylase. Now recognized to be two enzymes EC 7.2.4.2 [oxaloacetate decarboxylase (Na+ extruding)] and EC 4.1.1.112 (oxaloacetate decarboxylase). 
                EC 4.1.1.4                      acetoacetate decarboxylase 
                EC 4.1.1.5                      acetolactate decarboxylase 
                EC 4.1.1.6                      cis-aconitate decarboxylase 
                EC 4.1.1.7                      benzoylformate decarboxylase 
                EC 4.1.1.8                      oxalyl-CoA decarboxylase 
                EC 4.1.1.9                      malonyl-CoA decarboxylase 
                EC 4.1.1.10                      aminomalonate decarboxylase. Now included with EC 4.1.1.12, aspartate 4-decarboxylase 
                EC 4.1.1.11                      aspartate 1-decarboxylase 
                EC 4.1.1.12                      aspartate 4-decarboxylase 
                EC 4.1.1.13                       carbamoylaspartate decarboxylase 
                EC 4.1.1.14                      valine decarboxylase 
                EC 4.1.1.15                      glutamate decarboxylase 
                EC 4.1.1.16                      hydroxyglutamate decarboxylase 
                EC 4.1.1.17                      ornithine decarboxylase 
                EC 4.1.1.18                      lysine decarboxylase 
                EC 4.1.1.19                      arginine decarboxylase 
                EC 4.1.1.20                      diaminopimelate decarboxylase 
                EC 4.1.1.21                      phosphoribosylaminoimidazole carboxylase 
                EC 4.1.1.22                      histidine decarboxylase 
                EC 4.1.1.23                      orotidine-5′-phosphate decarboxylase 
                EC 4.1.1.24                      aminobenzoate decarboxylase 
                EC 4.1.1.25                      tyrosine decarboxylase 
                EC 4.1.1.26                       DOPA decarboxylase. Now included with EC 4.1.1.28 aromatic-L-amino-acid decarboxylase 
                EC 4.1.1.27                       tryptophan decarboxylase. Now included with EC 4.1.1.28 aromatic-L-amino-acid decarboxylase 
                EC 4.1.1.28                      aromatic-L-amino-acid decarboxylase 
                EC 4.1.1.29                      sulfinoalanine decarboxylase 
                EC 4.1.1.30                      pantothenoylcysteine decarboxylase 
                EC 4.1.1.31                      phosphoenolpyruvate carboxylase 
                EC 4.1.1.32                      phosphoenolpyruvate carboxykinase (GTP) 
                EC 4.1.1.33                      diphosphomevalonate decarboxylase 
                EC 4.1.1.34                      dehydro-L-gulonate decarboxylase 
                EC 4.1.1.35                      UDP-glucuronate decarboxylase 
                EC 4.1.1.36                      phosphopantothenoylcysteine decarboxylase 
                EC 4.1.1.37                      uroporphyrinogen decarboxylase 
                EC 4.1.1.38                      phosphoenolpyruvate carboxykinase (diphosphate) 
                EC 4.1.1.39                      ribulose-bisphosphate carboxylase 
                EC 4.1.1.40                      hydroxypyruvate decarboxylase 
                EC 4.1.1.41                      (S)-methylmalonyl-CoA decarboxylase. Now EC 7.2.4.3, (S)-methylmalonyl-CoA decarboxylase 
                EC 4.1.1.42                      carnitine decarboxylase 
                EC 4.1.1.43                      phenylpyruvate decarboxylase 
                EC 4.1.1.44                      4-carboxymuconolactone decarboxylase 
                EC 4.1.1.45                      aminocarboxymuconate-semialdehyde decarboxylase 
                EC 4.1.1.46                      o-pyrocatechuate decarboxylase 
                EC 4.1.1.47                      tartronate-semialdehyde synthase 
                EC 4.1.1.48                      indole-3-glycerol-phosphate synthase 
                EC 4.1.1.49                      phosphoenolpyruvate carboxykinase (ATP) 
                EC 4.1.1.50                      adenosylmethionine decarboxylase 
                EC 4.1.1.51                      3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase 
                EC 4.1.1.52                      6-methylsalicylate decarboxylase 
                EC 4.1.1.53                      phenylalanine decarboxylase 
                EC 4.1.1.54                      dihydroxyfumarate decarboxylase 
                EC 4.1.1.55                      4,5-dihydroxyphthalate decarboxylase 
                EC 4.1.1.56                      3-oxolaurate decarboxylase 
                EC 4.1.1.57                      methionine decarboxylase 
                EC 4.1.1.58                      orsellinate decarboxylase 
                EC 4.1.1.59                      gallate decarboxylase 
                EC 4.1.1.60                      stipitatonate decarboxylase 
                EC 4.1.1.61                      4-hydroxybenzoate decarboxylase 
                EC 4.1.1.62                      gentisate decarboxylase 
                EC 4.1.1.63                      protocatechuate decarboxylase 
                EC 4.1.1.64                      2,2-dialkylglycine decarboxylase (pyruvate) 
                EC 4.1.1.65                      phosphatidylserine decarboxylase 
                EC 4.1.1.66                      uracil-5-carboxylate decarboxylase 
                EC 4.1.1.67                      UDP-galacturonate decarboxylase 
                EC 4.1.1.68                      5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 
                EC 4.1.1.69                      3,4-dihydroxyphthalate decarboxylase 
                EC 4.1.1.70                      glutaconyl-CoA decarboxylase. Now EC 7.2.4.5, glutaconyl-CoA decarboxylase 
                EC 4.1.1.71                      2-oxoglutarate decarboxylase 
                EC 4.1.1.72                      branched-chain-2-oxoacid decarboxylase 
                EC 4.1.1.73                      tartrate decarboxylase 
                EC 4.1.1.74                      indolepyruvate decarboxylase 
                EC 4.1.1.75                      5-guanidino-2-oxopentanoate decarboxylase 
                EC 4.1.1.76                      arylmalonate decarboxylase 
                EC 4.1.1.77                      2-oxo-3-hexenedioate decarboxylase 
                EC 4.1.1.78                      acetylenedicarboxylate decarboxylase 
                EC 4.1.1.79                      sulfopyruvate decarboxylase 
                EC 4.1.1.80                      4-hydroxyphenylpyruvate decarboxylase 
                EC 4.1.1.81                      threonine-phosphate decarboxylase 
                EC 4.1.1.82                      phosphonopyruvate decarboxylase 
                EC 4.1.1.83                      4-hydroxyphenylacetate decarboxylase 
                EC 4.1.1.84                      D-dopachrome decarboxylase 
                EC 4.1.1.85                      3-dehydro-L-gulonate-6-phosphate decarboxylase 
                EC 4.1.1.86                      diaminobutyrate decarboxylase 
                EC 4.1.1.87                      malonyl-[malonate decarboxylase] decarboxylase 
                EC 4.1.1.88                      biotin-independent malonate decarboxylase 
                EC 4.1.1.89                      biotin-dependent malonate decarboxylase. Now EC 7.2.4.4, biotin-dependent malonate decarboxylase 
                EC 4.1.1.90                      peptidyl-glutamate 4-carboxylase 
                EC 4.1.1.91                      salicylate decarboxylase 
                EC 4.1.1.92                      indole-3-carboxylate decarboxylase 
                EC 4.1.1.93                      pyrrole-2-carboxylate decarboxylase 
                EC 4.1.1.94                      ethylmalonyl-CoA decarboxylase 
                EC 4.1.1.95                      L-glutamyl-[BtrI acyl-carrier protein] decarboxylase 
                EC 4.1.1.96                      carboxynorspermidine decarboxylase 
                EC 4.1.1.97                      2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase 
                EC 4.1.1.98                      4-hydroxy-3-polyprenylbenzoate decarboxylase 
                EC 4.1.1.99                      phosphomevalonate decarboxylase 
                EC 4.1.1.100                      prephenate decarboxylase 
                EC 4.1.1.101                      malolactic enzyme 
                EC 4.1.1.102                      phenacrylate decarboxylase 
                EC 4.1.1.103                      γ-resorcylate decarboxylase 
                EC 4.1.1.104                      3-dehydro-4-phosphotetronate decarboxylase 
                EC 4.1.1.105                      L-tryptophan decarboxylase 
                EC 4.1.1.106                      fatty acid photodecarboxylase 
                EC 4.1.1.107                      3,4-dihydroxyphenylacetaldehyde synthase 
                EC 4.1.1.108                      4-hydroxyphenylacetaldehyde synthase 
                EC 4.1.1.109                      phenylacetaldehyde synthase 
                EC 4.1.1.110                      bisphosphomevalonate decarboxylase 
                EC 4.1.1.111                      siroheme decarboxylase 
                EC 4.1.1.112                      oxaloacetate decarboxylase 
                EC 4.1.1.113                      trans-aconitate decarboxylase 
                EC 4.1.1.114                      cis-3-alkyl-4-alkyloxetan-2-one decarboxylase 
                EC 4.1.1.115                      indoleacetate decarboxylase 
                EC 4.1.1.116                      D-ornithine/D-lysine decarboxylase 
                EC 4.1.1.117                      2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase 
                EC 4.1.1.118                      isophthalyl-CoA decarboxylase 
                EC 4.1.1.119                      phenylacetate decarboxylase 
                EC 4.1.1.120                      3-oxoisoapionate decarboxylase 
                EC 4.1.1.121                      3-oxoisoapionate-4-phosphate decarboxylase 
                EC 4.1.1.122                      L-cysteate decarboxylase 
                EC 4.1.1.123                      phenyl-phosphate phosphatase/carboxylase 
                EC 4.1.1.124                      malonyl-[acp] decarboxylase 
                EC 4.1.1.125                      4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase 
                EC 4.1.1.126                      anhydromevalonate phosphate decarboxylase 
        EC 4.1.2       []    Aldehyde-lyases 
                EC 4.1.2.1                       hydroxyoxobutyrate aldolase. Now included with EC 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase 
                EC 4.1.2.2                      ketotetrose-phosphate aldolase 
                EC 4.1.2.3                       pentosealdolase 
                EC 4.1.2.4                      deoxyribose-phosphate aldolase 
                EC 4.1.2.5                      L-threonine aldolase 
                EC 4.1.2.6                       allothreonine aldolase. Reaction is due to EC 2.1.2.1, glycine hydroxymethyltransferase 
                EC 4.1.2.7                       ketose-1-phosphate aldolase. Now included with EC 4.1.2.13 fructose-bisphosphate aldolase 
                EC 4.1.2.8                      indole-3-glycerol-phosphate lyase 
                EC 4.1.2.9                      phosphoketolase 
                EC 4.1.2.10                      (R)-mandelonitrile lyase 
                EC 4.1.2.11                      hydroxymandelonitrile lyase 
                EC 4.1.2.12                      2-dehydropantoate aldolase 
                EC 4.1.2.13                      fructose-bisphosphate aldolase 
                EC 4.1.2.14                      2-dehydro-3-deoxy-phosphogluconate aldolase 
                EC 4.1.2.15                      2-dehydro-3-deoxy-phosphoheptonate aldolase. Now EC 2.5.1.54, 3-deoxy-7-phosphoheptulonate synthase 
                EC 4.1.2.16                      2-dehydro-3-deoxy-phosphooctonate aldolase. Now EC 2.5.1.55, 3-deoxy-8-phosphooctulonate synthase 
                EC 4.1.2.17                      L-fuculose-phosphate aldolase 
                EC 4.1.2.18                      2-dehydro-3-deoxy-L-pentonate aldolase 
                EC 4.1.2.19                      rhamnulose-1-phosphate aldolase 
                EC 4.1.2.20                      2-dehydro-3-deoxyglucarate aldolase 
                EC 4.1.2.21                      2-dehydro-3-deoxy-6-phosphogalactonate aldolase 
                EC 4.1.2.22                      fructose-6-phosphate phosphoketolase 
                EC 4.1.2.23                      3-deoxy-D-manno-octulosonate aldolase 
                EC 4.1.2.24                      dimethylaniline-N-oxide aldolase 
                EC 4.1.2.25                      dihydroneopterin aldolase 
                EC 4.1.2.26                      phenylserine aldolase 
                EC 4.1.2.27                      sphinganine-1-phosphate aldolase 
                EC 4.1.2.28                      2-dehydro-3-deoxy-D-pentonate aldolase 
                EC 4.1.2.29                      5-dehydro-2-deoxyphosphogluconate aldolase 
                EC 4.1.2.30                      17α-hydroxyprogesterone aldolase. Now EC 1.14.14.32, 17α-hydroxyprogesterone deacetylase 
                EC 4.1.2.31                       2-oxo-4-hydroxyglutarate aldolase. Now included with EC 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase 
                EC 4.1.2.32                      trimethylamine-oxide aldolase 
                EC 4.1.2.33                      fucosterol-epoxide lyase 
                EC 4.1.2.34                      4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase 
                EC 4.1.2.35                      propioin synthase 
                EC 4.1.2.36                      lactate aldolase 
                EC 4.1.2.37                      hydroxynitrilase. Now covered by EC 4.1.2.46 [aliphatic (R)-hydroxynitrile lyase] and EC 4.1.2.47 [(S)-hydroxynitrile ketone-lyase (cyanide forming)] 
                EC 4.1.2.38                      benzoin aldolase 
                EC 4.1.2.39                      hydroxynitrilase. The enzyme is identical to EC 4.1.2.37, hydroxynitrilase 
                EC 4.1.2.40                      tagatose-bisphosphate aldolase 
                EC 4.1.2.41                      vanillin synthase. Now included with EC 4.1.2.61, feruloyl-CoA hydratase/lyase 
                EC 4.1.2.42                      D-threonine aldolase 
                EC 4.1.2.43                      3-hexulose-6-phosphate synthase 
                EC 4.1.2.44                      2,3-epoxybenzoyl-CoA dihydrolase 
                EC 4.1.2.45                      trans-o-hydroxybenzylidenepyruvate hydratase-aldolase 
                EC 4.1.2.46                      aliphatic (R)-hydroxynitrile lyase 
                EC 4.1.2.47                      (S)-hydroxynitrile lyase 
                EC 4.1.2.48                      low-specificity L-threonine aldolase 
                EC 4.1.2.49                      L-allo-threonine aldolase 
                EC 4.1.2.50                      6-carboxytetrahydropterin synthase 
                EC 4.1.2.51                      2-dehydro-3-deoxy-D-gluconate aldolase  
                EC 4.1.2.52                      4-hydroxy-2-oxoheptanedioate aldolase 
                EC 4.1.2.53                      2-keto-3-deoxy-L-rhamnonate aldolase 
                EC 4.1.2.54                      L-threo-3-deoxy-hexylosonate aldolase 
                EC 4.1.2.55                      2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase  
                EC 4.1.2.56                      2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase 
                EC 4.1.2.57                      sulfofructosephosphate aldolase 
                EC 4.1.2.58                      2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase 
                EC 4.1.2.59                      dihydroneopterin phosphate aldolase 
                EC 4.1.2.60                      dihydroneopterin triphosphate aldolase 
                EC 4.1.2.61                      feruloyl-CoA hydratase/lyase 
                EC 4.1.2.62                      5-deoxyribulose 1-phosphate aldolase 
                EC 4.1.2.63                      2-hydroxyacyl-CoA lyase 
                EC 4.1.2.64                      2-dehydro-3-deoxy-L-fuconate aldolase 
        EC 4.1.3       []    Oxo-acid-lyases 
                EC 4.1.3.1                      isocitrate lyase 
                EC 4.1.3.2                      malate synthase. Now EC 2.3.3.9, malate synthase 
                EC 4.1.3.3                      N-acetylneuraminate lyase 
                EC 4.1.3.4                      hydroxymethylglutaryl-CoA lyase 
                EC 4.1.3.5                      hydroxymethylglutaryl-CoA synthase. Now EC 2.3.3.10, hydroxymethylglutaryl-CoA synthase 
                EC 4.1.3.6                      citrate (pro-3S)-lyase 
                EC 4.1.3.7                      citrate (Si)-synthase. Now EC 2.3.3.1, citrate (Si)-synthase 
                EC 4.1.3.8                      ATP citrate (pro-S)-lyase. Now EC 2.3.3.8, ATP citrate synthase 
                EC 4.1.3.9                      2-hydroxyglutarate synthase. Now EC 2.3.3.11, 2-hydroxyglutarate synthase 
                EC 4.1.3.10                      3-ethylmalate synthase. Now EC 2.3.3.7, 3-ethylmalate synthase 
                EC 4.1.3.11                      3-propylmalate synthase. Now EC 2.3.3.12, 3-propylmalate synthase 
                EC 4.1.3.12                      2-isopropylmalate synthase. Now EC 2.3.3.13, 2-isopropylmalate synthase 
                EC 4.1.3.13                      oxalomalate lyase 
                EC 4.1.3.14                      L-erythro-3-hydroxyaspartate aldolase 
                EC 4.1.3.15                      2-hydroxy-3-oxoadipate synthase. Now EC 2.2.1.5, 2-hydroxy-3-oxoadipate synthase 
                EC 4.1.3.16                      4-hydroxy-2-oxoglutarate aldolase 
                EC 4.1.3.17                      4-hydroxy-4-methyl-2-oxoglutarate aldolase 
                EC 4.1.3.18                      acetolactate synthase. Now EC 2.2.1.6, acetolactate synthase 
                EC 4.1.3.19                      N-acetylneuraminate synthase. Now EC 2.5.1.56, N-acetylneuraminate synthase 
                EC 4.1.3.20                      N-acylneuraminate-9-phosphate synthase. Now EC 2.5.1.57, N-acylneuraminate-9-phosphate synthase 
                EC 4.1.3.21                      homocitrate synthase. Now EC 2.3.3.14, homocitrate synthase 
                EC 4.1.3.22                      citramalate lyase 
                EC 4.1.3.23                      decylcitrate synthase. Now EC 2.3.3.2, decylcitrate synthase 
                EC 4.1.3.24                      malyl-CoA lyase 
                EC 4.1.3.25                      (S)-citramalyl-CoA lyase 
                EC 4.1.3.26                      3-hydroxy-3-isohexenylglutaryl-CoA lyase 
                EC 4.1.3.27                      anthranilate synthase 
                EC 4.1.3.28                      citrate (Re)-synthase. Now EC 2.3.3.3, citrate (Re)-synthase 
                EC 4.1.3.29                      decylhomocitrate synthase. Now EC 2.3.3.4, decylhomocitrate synthase 
                EC 4.1.3.30                      methylisocitrate lyase 
                EC 4.1.3.31                      2-methylcitrate synthase. Now EC 2.3.3.5, 2-methylcitrate synthase 
                EC 4.1.3.32                      2,3-dimethylmalate lyase 
                EC 4.1.3.33                      2-ethylmalate synthase. Now EC 2.3.3.6, 2-ethylmalate synthase 
                EC 4.1.3.34                      citryl-CoA lyase 
                EC 4.1.3.35                      (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase 
                EC 4.1.3.36                      1,4-dihydroxy-2-naphthoyl-CoA synthase 
                EC 4.1.3.37                      1-deoxy-D-xylulose 5-phosphate synthase. Now EC 2.2.1.7, 1-deoxy-D-xylulose 5-phosphate synthase 
                EC 4.1.3.38                      aminodeoxychorismate lyase 
                EC 4.1.3.39                      4-hydroxy-2-oxovalerate aldolase 
                EC 4.1.3.40                      chorismate lyase 
                EC 4.1.3.41                      3-hydroxy-D-aspartate aldolase 
                EC 4.1.3.42                      (4S)-4-hydroxy-2-oxoglutarate aldolase 
                EC 4.1.3.43                      4-hydroxy-2-oxohexanoate aldolase 
                EC 4.1.3.44                      tRNA 4-demethylwyosine synthase (AdoMet-dependent) 
                EC 4.1.3.45                      3-hydroxybenzoate synthase 
                EC 4.1.3.46                      (R)-citramalyl-CoA lyase 
        EC 4.1.99       []    Other carbon-carbon lyases 
                EC 4.1.99.1                      tryptophanase 
                EC 4.1.99.2                      tyrosine phenol-lyase 
                EC 4.1.99.3                      deoxyribodipyrimidine photo-lyase 
                EC 4.1.99.4                      1-aminocyclopropane-1-carboxylate deaminase. Now EC 3.5.99.7, 1-aminocyclopropane-1-carboxylate deaminase 
                EC 4.1.99.5                      aldehyde oxygenase (deformylating) 
                EC 4.1.99.6                      trichodiene synthase. Now EC 4.2.3.6, trichodiene synthase 
                EC 4.1.99.7                      aristolochene synthase. Now EC 4.2.3.9, aristolochene synthase 
                EC 4.1.99.8                      pinene synthase. Now EC 4.2.3.14, pinene synthase 
                EC 4.1.99.9                      myrcene synthase. Now EC 4.2.3.15, myrcene synthase 
                EC 4.1.99.10                      (-)-(4S)-limonene synthase. Now EC 4.2.3.16, (4S)-limonene synthase 
                EC 4.1.99.11                      benzylsuccinate synthase 
                EC 4.1.99.12                      3,4-dihydroxy-2-butanone-4-phosphate synthase 
                EC 4.1.99.13                      (6-4)DNA photolyase 
                EC 4.1.99.14                      spore photoproduct lyase 
                EC 4.1.99.15                      S-specific spore photoproduct lyase. This enzyme was classified on the basis of an incorrect reaction. The activity is covered by EC 4.1.99.14, spore photoproduct lyase 
                EC 4.1.99.16                      geosmin synthase 
                EC 4.1.99.17                      phosphomethylpyrimidine synthase 
                EC 4.1.99.18                      cyclic pyranopterin phosphate synthase. Now known to be catalysed by the combined effort of EC 4.1.99.22, GTP 3,8-cyclase, and EC 4.6.1.17, cyclic pyranopterin monophosphate synthase 
                EC 4.1.99.19                      2-iminoacetate synthase 
                EC 4.1.99.20                      3-amino-4-hydroxybenzoate synthase 
                EC 4.1.99.21                      (5-formylfuran-3-yl)methyl phosphate synthase. Now EC 4.2.3.153 (5-formylfuran-3-yl)methyl phosphate synthase. 
                EC 4.1.99.22                      GTP 3′,8-cyclase 
                EC 4.1.99.23                      5-hydroxybenzimidazole synthase 
                EC 4.1.99.24                      L-tyrosine isonitrile synthase 
                EC 4.1.99.25                      L-tryptophan isonitrile synthase 
                EC 4.1.99.26                      3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase 
                EC 4.1.99.27                      cyclopenase 
                EC 4.1.99.28                      3′-dehydrocarminate deglycosidase 
    EC 4.2  [+]      
        EC 4.2.1       []    Hydro-lyases 
                EC 4.2.1.1                      carbonic anhydrase 
                EC 4.2.1.2                      fumarate hydratase 
                EC 4.2.1.3                      aconitate hydratase 
                EC 4.2.1.4                      citrate dehydratase. Now known to be a partial reaction catalysed by EC 4.2.1.3, aconitate hydratase.  
                EC 4.2.1.5                      arabinonate dehydratase 
                EC 4.2.1.6                      galactonate dehydratase 
                EC 4.2.1.7                      altronate dehydratase 
                EC 4.2.1.8                      mannonate dehydratase 
                EC 4.2.1.9                      dihydroxy-acid dehydratase 
                EC 4.2.1.10                      3-dehydroquinate dehydratase 
                EC 4.2.1.11                      phosphopyruvate hydratase 
                EC 4.2.1.12                      phosphogluconate dehydratase 
                EC 4.2.1.13                      L-serine dehydratase. Now EC 4.3.1.17, L-serine ammonia-lyase 
                EC 4.2.1.14                      D-serine dehydratase. Now EC 4.3.1.18, D-serine ammonia-lyase 
                EC 4.2.1.15                       homoserine dehydratase. Identical with EC 4.4.1.1 cystathionine γ-lyase 
                EC 4.2.1.16                      threonine dehydratase. Now EC 4.3.1.19, threonine ammonia-lyase 
                EC 4.2.1.17                      enoyl-CoA hydratase 
                EC 4.2.1.18                      methylglutaconyl-CoA hydratase 
                EC 4.2.1.19                      imidazoleglycerol-phosphate dehydratase 
                EC 4.2.1.20                      tryptophan synthase 
                EC 4.2.1.21                       cystathionine β-synthase. Now EC 4.2.1.22 cystathionine β-synthase 
                EC 4.2.1.22                      cystathionine β-synthase 
                EC 4.2.1.23                       methylcysteine synthase. The reaction was due to a side-reaction of EC 4.2.1.22 cystathionine β-synthase 
                EC 4.2.1.24                      porphobilinogen synthase 
                EC 4.2.1.25                      L-arabinonate dehydratase 
                EC 4.2.1.26                      aminodeoxygluconate dehydratase. This enzyme was transferred to EC 4.3.1.21, aminodeoxygluconate ammonia-lyase, which has since been deleted. The enzyme is identical to EC 4.3.1.9, glucosaminate ammonia-lyase 
                EC 4.2.1.27                      acetylenecarboxylate hydratase 
                EC 4.2.1.28                      propanediol dehydratase 
                EC 4.2.1.29                      indoleacetaldoxime dehydratase. Now EC 4.99.1.6, indoleacetaldoxime dehydratase. The enzyme was classified incorrectly as a C-O lyase when the bond broken is a N-O bond 
                EC 4.2.1.30                      glycerol dehydratase 
                EC 4.2.1.31                      maleate hydratase 
                EC 4.2.1.32                      L(+)-tartrate dehydratase 
                EC 4.2.1.33                      3-isopropylmalate dehydratase 
                EC 4.2.1.34                      (S)-2-methylmalate dehydratase 
                EC 4.2.1.35                      (R)-2-methylmalate dehydratase 
                EC 4.2.1.36                      homoaconitate hydratase 
                EC 4.2.1.37                      trans-epoxysuccinate hydratase. Now EC 3.3.2.4, trans-epoxysuccinate hydrolase 
                EC 4.2.1.38                      erythro-3-hydroxyaspartate dehydratase. Now EC 4.3.1.20, erythro-3-hydroxyaspartate ammonia-lyase 
                EC 4.2.1.39                      gluconate dehydratase 
                EC 4.2.1.40                      glucarate dehydratase 
                EC 4.2.1.41                      5-dehydro-4-deoxyglucarate dehydratase 
                EC 4.2.1.42                      galactarate dehydratase 
                EC 4.2.1.43                      2-dehydro-3-deoxy-L-arabinonate dehydratase 
                EC 4.2.1.44                      myo-inosose-2 dehydratase 
                EC 4.2.1.45                      CDP-glucose 4,6-dehydratase 
                EC 4.2.1.46                      dTDP-glucose 4,6-dehydratase 
                EC 4.2.1.47                      GDP-mannose 4,6-dehydratase 
                EC 4.2.1.48                      D-glutamate cyclase 
                EC 4.2.1.49                      urocanate hydratase 
                EC 4.2.1.50                      pyrazolylalanine synthase 
                EC 4.2.1.51                      prephenate dehydratase 
                EC 4.2.1.52                      dihydrodipicolinate synthase. Now EC 4.3.3.7, 4-hydroxy-2,3,4,5-tetrahydrodipicolinate synthase. 
                EC 4.2.1.53                      oleate hydratase 
                EC 4.2.1.54                      lactoyl-CoA dehydratase 
                EC 4.2.1.55                      3-hydroxybutyryl-CoA dehydratase 
                EC 4.2.1.56                      itaconyl-CoA hydratase 
                EC 4.2.1.57                      isohexenylglutaconyl-CoA hydratase 
                EC 4.2.1.58                      crotonoyl-[acyl-carrier-protein] hydratase. The reaction described is covered by EC 4.2.1.59. 
                EC 4.2.1.59                      3-hydroxyacyl-[acyl-carrier-protein] dehydratase 
                EC 4.2.1.60                      3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase. The reaction described is covered by EC 4.2.1.59. 
                EC 4.2.1.61                      3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. The reaction described is covered by EC 4.2.1.59. 
                EC 4.2.1.62                      5α-hydroxysteroid dehydratase 
                EC 4.2.1.63                      epoxide hydratase. Now known to comprise two enzymes, microsomal epoxide hydrolase (EC 3.3.2.9) and soluble epoxide hydrolase (EC 3.3.2.10) 
                EC 4.2.1.64                      arene-oxide hydratase. Now known to comprise two enzymes, microsomal epoxide hydrolase (EC 3.3.2.9) and soluble epoxide hydrolase (EC 3.3.2.10) 
                EC 4.2.1.65                      3-cyanoalanine hydratase 
                EC 4.2.1.66                      cyanide hydratase 
                EC 4.2.1.67                      D-fuconate dehydratase 
                EC 4.2.1.68                      L-fuconate dehydratase 
                EC 4.2.1.69                      cyanamide hydratase 
                EC 4.2.1.70                      pseudouridylate synthase 
                EC 4.2.1.71                       acetylenecarboxylate hydratase. This enzyme is identical to EC 4.2.1.27, acetylenecarboxylate hydratase 
                EC 4.2.1.72                      acetylenedicarboxylate hydratase. Now EC 4.1.1.78, acetylenedicarboxylate decarboxylase 
                EC 4.2.1.73                      protoaphin-aglucone dehydratase (cyclizing) 
                EC 4.2.1.74                      medium-chain-enoyl-CoA hydratase 
                EC 4.2.1.75                      uroporphyrinogen-III synthase 
                EC 4.2.1.76                      UDP-glucose 4,6-dehydratase 
                EC 4.2.1.77                      trans-L-3-hydroxyproline dehydratase 
                EC 4.2.1.78                      (S)-norcoclaurine synthase 
                EC 4.2.1.79                      2-methylcitrate dehydratase 
                EC 4.2.1.80                      2-oxopent-4-enoate hydratase 
                EC 4.2.1.81                      D(-)-tartrate dehydratase 
                EC 4.2.1.82                      xylonate dehydratase 
                EC 4.2.1.83                      4-oxalomesaconate hydratase 
                EC 4.2.1.84                      nitrile hydratase 
                EC 4.2.1.85                      dimethylmaleate hydratase 
                EC 4.2.1.86                       16-dehydroprogesterone hydratase (reaction is identical to that of EC 4.2.1.98, 16α-hydroxyprogesterone dehydratase) 
                EC 4.2.1.87                      octopamine dehydratase 
                EC 4.2.1.88                      synephrine dehydratase 
                EC 4.2.1.89                      carnitine dehydratase. The activity has now been shown to be due to EC 2.8.3.21, L-carnitine CoA-transferase and EC 4.2.1.149, crotonobetainyl-CoA hydratase. 
                EC 4.2.1.90                      L-rhamnonate dehydratase 
                EC 4.2.1.91                      arogenate dehydratase 
                EC 4.2.1.92                      hydroperoxide dehydratase 
                EC 4.2.1.93                      ATP-dependent NAD(P)H-hydrate dehydratase 
                EC 4.2.1.94                      scytalone dehydratase 
                EC 4.2.1.95                      kievitone hydratase 
                EC 4.2.1.96                      4a-hydroxytetrahydrobiopterin dehydratase 
                EC 4.2.1.97                      phaseollidin hydratase 
                EC 4.2.1.98                      16α-hydroxyprogesterone dehydratase 
                EC 4.2.1.99                      2-methylisocitrate dehydratase 
                EC 4.2.1.100                      cyclohexa-1,5-dienecarbonyl-CoA hydratase 
                EC 4.2.1.101                      trans-feruloyl-CoA hydratase. Now included with EC 4.1.2.61, feruloyl-CoA hydratase/lyase 
                EC 4.2.1.102                      cyclohexa-1,5-dienecarbonyl-CoA hydratase. Now EC 4.2.1.100, cyclohexa-1,5-dienecarbonyl-CoA hydratase 
                EC 4.2.1.103                      cyclohexyl-isocyanide hydratase 
                EC 4.2.1.104                      cyanase 
                EC 4.2.1.105                      2-hydroxyisoflavanone dehydratase 
                EC 4.2.1.106                      bile-acid 7α-dehydratase 
                EC 4.2.1.107                      3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA hydratase 
                EC 4.2.1.108                      ectoine synthase 
                EC 4.2.1.109                      methylthioribulose 1-phosphate dehydratase 
                EC 4.2.1.110                      aldos-2-ulose dehydratase 
                EC 4.2.1.111                      1,5-anhydro-D-fructose dehydratase 
                EC 4.2.1.112                      acetylene hydratase 
                EC 4.2.1.113                      o-succinylbenzoate synthase 
                EC 4.2.1.114                      methanogen homoaconitase 
                EC 4.2.1.115                      UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) 
                EC 4.2.1.116                      3-hydroxypropionyl-CoA dehydratase 
                EC 4.2.1.117                      2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) 
                EC 4.2.1.118                      3-dehydroshikimate dehydratase 
                EC 4.2.1.119                      enoyl-CoA hydratase 2 
                EC 4.2.1.120                      4-hydroxybutanoyl-CoA dehydratase 
                EC 4.2.1.121                      colneleate synthase 
                EC 4.2.1.122                      tryptophan synthase (indole-salvaging) 
                EC 4.2.1.123                      tetrahymanol synthase 
                EC 4.2.1.124                      arabidiol synthase 
                EC 4.2.1.125                      dammarenediol II synthase 
                EC 4.2.1.126                      N-acetylmuramic acid 6-phosphate etherase 
                EC 4.2.1.127                      linalool dehydratase 
                EC 4.2.1.128                      lupan-3β,20-diol synthase 
                EC 4.2.1.129                      squalene—hopanol cyclase 
                EC 4.2.1.130                      D-lactate dehydratase 
                EC 4.2.1.131                      carotenoid 1,2-hydratase 
                EC 4.2.1.132                      2-hydroxyhexa-2,4-dienoate hydratase 
                EC 4.2.1.133                      copal-8-ol diphosphate hydratase 
                EC 4.2.1.134                      very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 
                EC 4.2.1.135                      UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) 
                EC 4.2.1.136                      ADP-dependent NAD(P)H-hydrate dehydratase 
                EC 4.2.1.137                      sporulenol synthase 
                EC 4.2.1.138                      (+)-caryolan-1-ol synthase 
                EC 4.2.1.139                      pterocarpan synthase 
                EC 4.2.1.140                      gluconate/galactonate dehydratase  
                EC 4.2.1.141                      2-dehydro-3-deoxy-D-arabinonate dehydratase 
                EC 4.2.1.142                      5′-oxoaverantin cyclase 
                EC 4.2.1.143                      versicolorin B synthase 
                EC 4.2.1.144                      3-amino-5-hydroxybenzoate synthase 
                EC 4.2.1.145                      capreomycidine synthase 
                EC 4.2.1.146                      L-galactonate dehydratase 
                EC 4.2.1.147                      5,6,7,8-tetrahydromethanopterin hydro-lyase 
                EC 4.2.1.148                      2-methylfumaryl-CoA hydratase 
                EC 4.2.1.149                      crotonobetainyl-CoA hydratase 
                EC 4.2.1.150                      short-chain-enoyl-CoA hydratase 
                EC 4.2.1.151                      chorismate dehydratase 
                EC 4.2.1.152                      hydroperoxy icosatetraenoate dehydratase 
                EC 4.2.1.153                      3-methylfumaryl-CoA hydratase 
                EC 4.2.1.154                      tetracenomycin F2 cyclase 
                EC 4.2.1.155                      (methylthio)acryloyl-CoA hydratase 
                EC 4.2.1.156                      L-talarate dehydratase 
                EC 4.2.1.157                      (R)-2-hydroxyisocaproyl-CoA dehydratase 
                EC 4.2.1.158                      galactarate dehydratase (D-threo-forming) 
                EC 4.2.1.159                      dTDP-4-dehydro-6-deoxy-α-D-glucopyranose 2,3-dehydratase 
                EC 4.2.1.160                      2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase 
                EC 4.2.1.161                      bisanhydrobacterioruberin hydratase 
                EC 4.2.1.162                      6-deoxy-6-sulfo-D-gluconate dehydratase 
                EC 4.2.1.163                      2-oxo-hept-4-ene-1,7-dioate hydratase 
                EC 4.2.1.164                      dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase 
                EC 4.2.1.165                      chlorophyllide a 31-hydratase 
                EC 4.2.1.166                      phosphinomethylmalate isomerase 
                EC 4.2.1.167                      (R)-2-hydroxyglutaryl-CoA dehydratase 
                EC 4.2.1.168                      GDP-4-dehydro-6-deoxy-α-D-mannose 3-dehydratase 
                EC 4.2.1.169                      3-vinyl bacteriochlorophyllide d 31-hydratase 
                EC 4.2.1.170                      2-(ω-methylthio)alkylmalate dehydratase 
                EC 4.2.1.171                      cis-L-3-hydroxyproline dehydratase 
                EC 4.2.1.172                      trans-4-hydroxy-L-proline dehydratase 
                EC 4.2.1.173                      ent-8α-hydroxylabd-13-en-15-yl diphosphate synthase 
                EC 4.2.1.174                      peregrinol diphosphate synthase 
                EC 4.2.1.175                      (R)-3-(aryl)lactoyl-CoA dehydratase 
                EC 4.2.1.176                      L-lyxonate dehydratase 
                EC 4.2.1.177                      (2S)-3-sulfopropanediol dehydratase 
                EC 4.2.1.178                      difructose-dianhydride-III synthase 
                EC 4.2.1.179                      difructose-anhydride-I synthase 
                EC 4.2.1.180                      (E)-benzylidenesuccinyl-CoA hydratase 
                EC 4.2.1.181                      3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase 
                EC 4.2.1.182                      phosphomevalonate dehydratase 
        EC 4.2.2       []    Acting on polysaccharides 
                EC 4.2.2.1                      hyaluronate lyase 
                EC 4.2.2.2                      pectate lyase 
                EC 4.2.2.3                      mannuronate-specific alginate lyase 
                EC 4.2.2.4                      chondroitin ABC lyase. Now known to comprise two enzymes: EC 4.2.2.20, chondroitin-sulfate-ABC endolyase and EC 4.2.2.21, chondroitin-sulfate-ABC exolyase 
                EC 4.2.2.5                      chondroitin AC lyase 
                EC 4.2.2.6                      oligogalacturonide lyase 
                EC 4.2.2.7                      heparin lyase 
                EC 4.2.2.8                      heparin-sulfate lyase 
                EC 4.2.2.9                      pectate disaccharide-lyase 
                EC 4.2.2.10                      pectin lyase 
                EC 4.2.2.11                      guluronate-specific alginate lyase 
                EC 4.2.2.12                      xanthan lyase 
                EC 4.2.2.13                      exo-(1→4)-α-D-glucan lyase 
                EC 4.2.2.14                      glucuronan lyase 
                EC 4.2.2.15                      anhydrosialidase 
                EC 4.2.2.16                      levan fructotransferase (DFA-IV-forming) 
                EC 4.2.2.17                      inulin fructotransferase (DFA-I-forming) 
                EC 4.2.2.18                      inulin fructotransferase (DFA-III-forming) 
                EC 4.2.2.19                      chondroitin B lyase 
                EC 4.2.2.20                      chondroitin-sulfate-ABC endolyase 
                EC 4.2.2.21                      chondroitin-sulfate-ABC exolyase 
                EC 4.2.2.22                      pectate trisaccharide-lyase 
                EC 4.2.2.23                      rhamnogalacturonan endolyase 
                EC 4.2.2.24                      rhamnogalacturonan exolyase 
                EC 4.2.2.25                      gellan lyase 
                EC 4.2.2.26                      oligo-alginate lyase 
                EC 4.2.2.27                      pectin monosaccharide-lyase 
                EC 4.2.2.28                      α-L-rhamnosyl-(1→4)-β-D-glucuronate lyase 
                EC 4.2.2.29                      peptidoglycan lytic transglycosylase 
        EC 4.2.3       []    Acting on phosphates 
                EC 4.2.3.1                      threonine synthase 
                EC 4.2.3.2                      ethanolamine-phosphate phospho-lyase 
                EC 4.2.3.3                      methylglyoxal synthase 
                EC 4.2.3.4                      3-dehydroquinate synthase 
                EC 4.2.3.5                      chorismate synthase 
                EC 4.2.3.6                      trichodiene synthase 
                EC 4.2.3.7                      pentalenene synthase 
                EC 4.2.3.8                      casbene synthase 
                EC 4.2.3.9                      aristolochene synthase 
                EC 4.2.3.10                      (-)-endo-fenchol synthase 
                EC 4.2.3.11                      sabinene-hydrate synthase 
                EC 4.2.3.12                      6-pyruvoyltetrahydropterin synthase 
                EC 4.2.3.13                      (+)-δ-cadinene synthase 
                EC 4.2.3.14                      pinene synthase. Now covered by EC 4.2.3.119, (-)-α-pinene synthase, and EC 4.2.3.120, (-)-β-pinene synthase 
                EC 4.2.3.15                      myrcene synthase 
                EC 4.2.3.16                      (4S)-limonene synthase 
                EC 4.2.3.17                      taxadiene synthase 
                EC 4.2.3.18                      abieta-7,13-diene synthase 
                EC 4.2.3.19                      ent-kaurene synthase 
                EC 4.2.3.20                      (R)-limonene synthase 
                EC 4.2.3.21                      vetispiradiene synthase 
                EC 4.2.3.22                      germacradienol synthase 
                EC 4.2.3.23                      germacrene-A synthase 
                EC 4.2.3.24                      amorpha-4,11-diene synthase 
                EC 4.2.3.25                      S-linalool synthase 
                EC 4.2.3.26                      R-linalool synthase 
                EC 4.2.3.27                      isoprene synthase 
                EC 4.2.3.28                      ent-cassa-12,15-diene synthase 
                EC 4.2.3.29                      ent-sandaracopimaradiene synthase 
                EC 4.2.3.30                      ent-pimara-8(14),15-diene synthase 
                EC 4.2.3.31                      ent-pimara-9(11),15-diene synthase 
                EC 4.2.3.32                      levopimaradiene synthase 
                EC 4.2.3.33                      stemar-13-ene synthase 
                EC 4.2.3.34                      stemod-13(17)-ene synthase 
                EC 4.2.3.35                      syn-pimara-7,15-diene synthase 
                EC 4.2.3.36                      terpentetriene synthase 
                EC 4.2.3.37                      epi-isozizaene synthase 
                EC 4.2.3.38                      α-bisabolene synthase 
                EC 4.2.3.39                      epi-cedrol synthase 
                EC 4.2.3.40                      (Z)-γ-bisabolene synthase 
                EC 4.2.3.41                      elisabethatriene synthase 
                EC 4.2.3.42                      aphidicolan-16β-ol synthase 
                EC 4.2.3.43                      fusicocca-2,10(14)-diene synthase 
                EC 4.2.3.44                      isopimara-7,15-diene synthase 
                EC 4.2.3.45                      phyllocladan-16α-ol synthase 
                EC 4.2.3.46                      α-farnesene synthase 
                EC 4.2.3.47                      β-farnesene synthase 
                EC 4.2.3.48                      (3S,6E)-nerolidol synthase 
                EC 4.2.3.49                      (3R,6E)-nerolidol synthase 
                EC 4.2.3.50                      (+)-α-santalene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] 
                EC 4.2.3.51                      β-phellandrene synthase (neryl-diphosphate-cyclizing) 
                EC 4.2.3.52                      (4S)-β-phellandrene synthase (geranyl-diphosphate-cyclizing) 
                EC 4.2.3.53                      (+)-endo-β-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] 
                EC 4.2.3.54                      (-)-endo-α-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] 
                EC 4.2.3.55                      (S)-β-bisabolene synthase 
                EC 4.2.3.56                      γ-humulene synthase 
                EC 4.2.3.57                      (-)-β-caryophyllene synthase 
                EC 4.2.3.58                      longifolene synthase 
                EC 4.2.3.59                      (E)-γ-bisabolene synthase 
                EC 4.2.3.60                      germacrene C synthase 
                EC 4.2.3.61                      5-epiaristolochene synthase 
                EC 4.2.3.62                      (-)-γ-cadinene synthase [(2Z,6E)-farnesyl diphosphate cyclizing] 
                EC 4.2.3.63                      (+)-cubenene synthase 
                EC 4.2.3.64                      (+)-epicubenol synthase 
                EC 4.2.3.65                      zingiberene synthase 
                EC 4.2.3.66                      β-selinene cyclase 
                EC 4.2.3.67                      cis-muuroladiene synthase 
                EC 4.2.3.68                      β-eudesmol synthase 
                EC 4.2.3.69                      (+)-α-barbatene synthase 
                EC 4.2.3.70                      patchoulol synthase 
                EC 4.2.3.71                      (E,E)-germacrene B synthase 
                EC 4.2.3.72                      α-gurjunene synthase 
                EC 4.2.3.73                      valencene synthase 
                EC 4.2.3.74                      presilphiperfolanol synthase 
                EC 4.2.3.75                      (-)-germacrene D synthase 
                EC 4.2.3.76                      (+)-δ-selinene synthase 
                EC 4.2.3.77                      (+)-germacrene D synthase 
                EC 4.2.3.78                      β-chamigrene synthase 
                EC 4.2.3.79                      thujopsene synthase 
                EC 4.2.3.80                      α-longipinene synthase 
                EC 4.2.3.81                      exo-α-bergamotene synthase 
                EC 4.2.3.82                      α-santalene synthase 
                EC 4.2.3.83                      β-santalene synthase 
                EC 4.2.3.84                      10-epi-γ-eudesmol synthase 
                EC 4.2.3.85                      α-eudesmol synthase 
                EC 4.2.3.86                      7-epi-α-selinene synthase 
                EC 4.2.3.87                      α-guaiene synthase 
                EC 4.2.3.88                      viridiflorene synthase 
                EC 4.2.3.89                      (+)-β-caryophyllene synthase 
                EC 4.2.3.90                      5-epi-α-selinene synthase 
                EC 4.2.3.91                      cubebol synthase 
                EC 4.2.3.92                      (+)-γ-cadinene synthase 
                EC 4.2.3.93                      δ-guaiene synthase 
                EC 4.2.3.94                      γ-curcumene synthase 
                EC 4.2.3.95                      (-)-α-cuprenene synthase 
                EC 4.2.3.96                      avermitilol synthase 
                EC 4.2.3.97                      (-)-δ-cadinene synthase 
                EC 4.2.3.98                      (+)-T-muurolol synthase 
                EC 4.2.3.99                      labdatriene synthase 
                EC 4.2.3.100                      bicyclogermacrene synthase 
                EC 4.2.3.101                      7-epi-sesquithujene synthase 
                EC 4.2.3.102                      sesquithujene synthase 
                EC 4.2.3.103                      ent-isokaurene synthase 
                EC 4.2.3.104                      α-humulene synthase 
                EC 4.2.3.105                      tricyclene synthase 
                EC 4.2.3.106                      (E)-β-ocimene synthase 
                EC 4.2.3.107                      (+)-car-3-ene synthase 
                EC 4.2.3.108                      1,8-cineole synthase 
                EC 4.2.3.109                      (-)-sabinene synthase 
                EC 4.2.3.110                      (+)-sabinene synthase 
                EC 4.2.3.111                      (-)-α-terpineol synthase 
                EC 4.2.3.112                      (+)-α-terpineol synthase 
                EC 4.2.3.113                      terpinolene synthase 
                EC 4.2.3.114                      γ-terpinene synthase 
                EC 4.2.3.115                      α-terpinene synthase 
                EC 4.2.3.116                      (+)-camphene synthase 
                EC 4.2.3.117                      (-)-camphene synthase 
                EC 4.2.3.118                      2-methylisoborneol synthase 
                EC 4.2.3.119                      (-)-α-pinene synthase 
                EC 4.2.3.120                      (-)-β-pinene synthase 
                EC 4.2.3.121                      (+)-α-pinene synthase 
                EC 4.2.3.122                      (+)-β-pinene synthase 
                EC 4.2.3.123                      β-sesquiphellandrene synthase 
                EC 4.2.3.124                      2-deoxy-scyllo-inosose synthase 
                EC 4.2.3.125                      α-muurolene synthase 
                EC 4.2.3.126                      γ-muurolene synthase 
                EC 4.2.3.127                      β-copaene synthase 
                EC 4.2.3.128                      β-cubebene synthase 
                EC 4.2.3.129                      (+)-sativene synthase 
                EC 4.2.3.130                      tetraprenyl-β-curcumene synthase 
                EC 4.2.3.131                      miltiradiene synthase 
                EC 4.2.3.132                      neoabietadiene synthase 
                EC 4.2.3.133                      α-copaene synthase 
                EC 4.2.3.134                      5-phosphooxy-L-lysine phospho-lyase 
                EC 4.2.3.135                      Δ6-protoilludene synthase 
                EC 4.2.3.136                      α-isocomene synthase 
                EC 4.2.3.137                      (E)-2-epi-β-caryophyllene synthase 
                EC 4.2.3.138                      (+)-epi-α-bisabolol synthase 
                EC 4.2.3.139                      valerena-4,7(11)-diene synthase 
                EC 4.2.3.140                      cis-abienol synthase 
                EC 4.2.3.141                      sclareol synthase 
                EC 4.2.3.142                      7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] 
                EC 4.2.3.143                      kunzeaol synthase 
                EC 4.2.3.144                      geranyllinalool synthase 
                EC 4.2.3.145                      ophiobolin F synthase 
                EC 4.2.3.146                      cyclooctat-9-en-7-ol synthase 
                EC 4.2.3.147                      pimaradiene synthase 
                EC 4.2.3.148                      cembrene C synthase 
                EC 4.2.3.149                      nephthenol synthase 
                EC 4.2.3.150                      cembrene A synthase 
                EC 4.2.3.151                      pentamethylcyclopentadecatrienol synthase 
                EC 4.2.3.152                      2-epi-5-epi-valiolone synthase 
                EC 4.2.3.153                      (5-formylfuran-3-yl)methyl phosphate synthase 
                EC 4.2.3.154                      demethyl-4-deoxygadusol synthase 
                EC 4.2.3.155                      2-epi-valiolone synthase 
                EC 4.2.3.156                      hydroxysqualene synthase 
                EC 4.2.3.157                      (+)-isoafricanol synthase 
                EC 4.2.3.158                      (–)-spiroviolene synthase 
                EC 4.2.3.159                      tsukubadiene synthase 
                EC 4.2.3.160                      (2S,3R,6S,9S)-(–)-protoillud-7-ene synthase 
                EC 4.2.3.161                      (3S)-(+)-asterisca-2(9),6-diene synthase 
                EC 4.2.3.162                      (–)-α-amorphene synthase 
                EC 4.2.3.163                      (+)-corvol ether B synthase 
                EC 4.2.3.164                      (+)-eremophilene synthase 
                EC 4.2.3.165                      (1R,4R,5S)-(–)-guaia-6,10(14)-diene synthase 
                EC 4.2.3.166                      (+)-(1E,4E,6S,7R)-germacra-1(10),4-dien-6-ol synthase 
                EC 4.2.3.167                      dolabella-3,7-dien-18-ol synthase 
                EC 4.2.3.168                      dolathalia-3,7,11-triene synthase 
                EC 4.2.3.169                      7-epi-α-eudesmol synthase 
                EC 4.2.3.170                      4-epi-cubebol synthase 
                EC 4.2.3.171                      (+)-corvol ether A synthase 
                EC 4.2.3.172                      10-epi-juneol synthase 
                EC 4.2.3.173                      τ-cadinol synthase 
                EC 4.2.3.174                      (2E,6E)-hedycaryol synthase 
                EC 4.2.3.175                      10-epi-cubebol synthase 
                EC 4.2.3.176                      sesterfisherol synthase 
                EC 4.2.3.177                      β-thujene synthase 
                EC 4.2.3.178                      stellata-2,6,19-triene synthase 
                EC 4.2.3.179                      guaia-4,6-diene synthase 
                EC 4.2.3.180                      pseudolaratriene synthase 
                EC 4.2.3.181                      selina-4(15),7(11)-diene synthase 
                EC 4.2.3.182                      pristinol synthase 
                EC 4.2.3.183                      nezukol synthase 
                EC 4.2.3.184                      5-hydroxy-α-gurjunene synthase 
                EC 4.2.3.185                      ent-atiserene synthase 
                EC 4.2.3.186                      ent-13-epi-manoyl oxide synthase 
                EC 4.2.3.187                      (2Z,6E)-hedycaryol synthase 
                EC 4.2.3.188                      β-geranylfarnesene synthase 
                EC 4.2.3.189                      9,13-epoxylabd-14-ene synthase 
                EC 4.2.3.190                      manoyl oxide synthase 
                EC 4.2.3.191                      cycloaraneosene synthase 
                EC 4.2.3.192                      labda-7,13(16),14-triene synthase 
                EC 4.2.3.193                      (12E)-labda-8(17),12,14-triene synthase 
                EC 4.2.3.194                      (–)-drimenol synthase 
                EC 4.2.3.195                      rhizathalene A synthase 
                EC 4.2.3.196                      dolabradiene synthase 
                EC 4.2.3.197                      eudesmane-5,11-diol synthase 
                EC 4.2.3.198                      α-selinene synthase 
                EC 4.2.3.199                      (–)-5-epieremophilene synthase 
                EC 4.2.3.200                      β-pinacene synthase 
                EC 4.2.3.201                      hydropyrene synthase 
                EC 4.2.3.202                      hydropyrenol synthase 
                EC 4.2.3.203                      isoelisabethatriene synthase 
                EC 4.2.3.204                      valerianol synthase 
                EC 4.2.3.205                      sodorifen synthase 
                EC 4.2.3.206                      (–)-cyatha-3,12-diene synthase 
                EC 4.2.3.207                      neoverrucosan-5β-ol synthase 
                EC 4.2.3.208                      verrucosan-2β-ol synthase 
                EC 4.2.3.209                      (R)-axinyssene synthase 
                EC 4.2.3.210                      lydicene synthase 
                EC 4.2.3.211                      (+)-exo-β-bergamotene synthase 
                EC 4.2.3.212                      (+)-δ-cadinol synthase 
                EC 4.2.3.213                      colleterpenol synthase 
                EC 4.2.3.214                      dolasta-1(15),8-diene synthase 
                EC 4.2.3.215                      δ-araneosene synthase 
                EC 4.2.3.216                      somaliensene A synthase 
                EC 4.2.3.217                      somaliensene B synthase 
                EC 4.2.3.218                      variediene synthase 
                EC 4.2.3.219                      (2E)-α-cericerene synthase 
        EC 4.2.99       []    Other carbon-oxygen lyases 
                EC 4.2.99.1                      hyaluronate lyase. Now EC 4.2.2.1, hyaluronate lyase 
                EC 4.2.99.2                      threonine synthase. Now EC 4.2.3.1, threonine synthase 
                EC 4.2.99.3                      pectate lyase. Now EC 4.2.2.2, pectate lyase 
                EC 4.2.99.4                      alginate lyase. Now EC 4.2.2.3, poly(β-D-mannuronate) lyase 
                EC 4.2.99.5                       polyglucuronide lyase 
                EC 4.2.99.6                       chondroitin sulfate lyase. Now included with EC 4.2.2.4 (chondroitin ABC lyase) and EC 4.2.2.5 (chondroitin AC lyase) 
                EC 4.2.99.7                      ethanolamine-phosphate phospho-lyase. Now EC 4.2.3.2, ethanolamine-phosphate phospho-lyase 
                EC 4.2.99.8                      cysteine synthase. Now EC 2.5.1.47, cysteine synthase 
                EC 4.2.99.9                      O-succinylhomoserine (thiol)-lyase. Now EC 2.5.1.48, cystathionine γ-synthase 
                EC 4.2.99.10                      O-acetylhomoserine (thiol)-lyase. Now EC 2.5.1.49, O-acetylhomoserine aminocarboxypropyltransferase 
                EC 4.2.99.11                      methylglyoxal synthase. Now EC 4.2.3.3, methylglyoxal synthase 
                EC 4.2.99.12                      carboxymethyloxysuccinate lyase 
                EC 4.2.99.13                      β-(9-cytokinin)-alanine synthase. Now EC 2.5.1.50, zeatin 9-aminocarboxyethyltransferase 
                EC 4.2.99.14                      β-pyrazolylalanine synthase (acetylserine). Now EC 2.5.1.51, β-pyrazolylalanine synthase 
                EC 4.2.99.15                      L-mimosine synthase. Now EC 2.5.1.52, L-mimosine synthase 
                EC 4.2.99.16                      uracilylalanine synthase. Now EC 2.5.1.53, uracilylalanine synthase 
                EC 4.2.99.17                      thermopsin. Listed as EC 2.5.1.51, β-pyrazolylalanine synthase 
                EC 4.2.99.18                      DNA-(apurinic or apyrimidinic site) lyase 
                EC 4.2.99.19                      2-hydroxypropyl-CoM lyase. Now EC 4.4.1.23, 2-hydroxypropyl-CoM lyase. The enzyme was incorrectly classified as acting on a C-O bond rather than a C-S bond 
                EC 4.2.99.20                      2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 
                EC 4.2.99.21                      isochorismate lyase 
                EC 4.2.99.22                      tuliposide A-converting enzyme 
                EC 4.2.99.23                      tuliposide B-converting enzyme 
                EC 4.2.99.24                      thebaine synthase 
                EC 4.2.99.25                      unsaturated pyranuronate lyase 
    EC 4.3  [+]      
        EC 4.3.1       []    Ammonia-lyases 
                EC 4.3.1.1                      aspartate ammonia-lyase 
                EC 4.3.1.2                      methylaspartate ammonia-lyase 
                EC 4.3.1.3                      histidine ammonia-lyase 
                EC 4.3.1.4                      formimidoyltetrahydrofolate cyclodeaminase 
                EC 4.3.1.5                      phenylalanine ammonia-lyase. Now divided into EC 4.3.1.23 (tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase) 
                EC 4.3.1.6                      β-alanyl-CoA ammonia-lyase 
                EC 4.3.1.7                      ethanolamine ammonia-lyase 
                EC 4.3.1.8                      hydroxymethylbilane synthase. Now EC 2.5.1.61, hydroxymethylbilane synthase 
                EC 4.3.1.9                      glucosaminate ammonia-lyase 
                EC 4.3.1.10                      serine-sulfate ammonia-lyase 
                EC 4.3.1.11                      dihydroxyphenylalanine ammonia-lyase. The entry had been drafted on the basis of a single abstract that did not provide experimental evidence of the enzyme-catalysed reaction 
                EC 4.3.1.12                      ornithine cyclodeaminase 
                EC 4.3.1.13                      carbamoyl-serine ammonia-lyase 
                EC 4.3.1.14                      3-aminobutyryl-CoA ammonia-lyase 
                EC 4.3.1.15                      diaminopropionate ammonia-lyase 
                EC 4.3.1.16                      threo-3-hydroxy-L-aspartate ammonia-lyase 
                EC 4.3.1.17                      L-serine ammonia-lyase 
                EC 4.3.1.18                      D-serine ammonia-lyase 
                EC 4.3.1.19                      threonine ammonia-lyase 
                EC 4.3.1.20                      erythro-3-hydroxy-L-aspartate ammonia-lyase 
                EC 4.3.1.21                       aminodeoxygluconate ammonia-lyase. Enzyme is identical to EC 4.3.1.9, glucosaminate ammonia-lyase 
                EC 4.3.1.22                      3,4-dihydroxyphenylalanine reductive deaminase 
                EC 4.3.1.23                      tyrosine ammonia-lyase 
                EC 4.3.1.24                      phenylalanine ammonia-lyase 
                EC 4.3.1.25                      phenylalanine/tyrosine ammonia-lyase 
                EC 4.3.1.26                      chromopyrrolate synthase. Now EC 1.21.3.9, dichlorochromopyrrolate synthase 
                EC 4.3.1.27                      threo-3-hydroxy-D-aspartate ammonia-lyase 
                EC 4.3.1.28                      L-lysine cyclodeaminase 
                EC 4.3.1.29                      D-glucosaminate-6-phosphate ammonia-lyase 
                EC 4.3.1.30                      dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase 
                EC 4.3.1.31                      L-tryptophan ammonia lyase 
                EC 4.3.1.32                      7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase 
                EC 4.3.1.33                      (R)-1-hydroxy-2-aminoethylphosphonate ammonia-lyase 
        EC 4.3.2       []    Amidine-lyases 
                EC 4.3.2.1                      argininosuccinate lyase 
                EC 4.3.2.2                      adenylosuccinate lyase 
                EC 4.3.2.3                      ureidoglycolate lyase 
                EC 4.3.2.4                      purine imidazole-ring cyclase 
                EC 4.3.2.5                      peptidylamidoglycolate lyase 
                EC 4.3.2.6                      γ-L-glutamyl-butirosin B γ-glutamyl cyclotransferase 
                EC 4.3.2.7                      glutathione-specific γ-glutamylcyclotransferase 
                EC 4.3.2.8                      γ-glutamylamine cyclotransferase 
                EC 4.3.2.9                      γ-glutamylcyclotransferase 
                EC 4.3.2.10                      imidazole glycerol-phosphate synthase 
                EC 4.3.2.11                      (3R)-3-[(carboxylmethyl)amino]fatty acid synthase 
        EC 4.3.3       []    Amine-lyases 
                EC 4.3.3.1                      3-ketovalidoxylamine C-N-lyase 
                EC 4.3.3.2                      strictosidine synthase 
                EC 4.3.3.3                      deacetylisoipecoside synthase 
                EC 4.3.3.4                      deacetylipecoside synthase 
                EC 4.3.3.5                      4′-demethylrebeccamycin synthase 
                EC 4.3.3.6                      pyridoxal 5′-phosphate synthase (glutamine hydrolysing) 
                EC 4.3.3.7                      4-hydroxy-tetrahydrodipicolinate synthase 
                EC 4.3.3.8                      mimosinase 
        EC 4.3.99       []    Other carbon-nitrogen lyases 
                EC 4.3.99.1                      cyanate lyase. Now EC 4.2.1.104, cyanate hydratase 
                EC 4.3.99.2                      carboxybiotin decarboxylase. Now EC 7.2.4.1, carboxybiotin decarboxylase 
                EC 4.3.99.3                      7-carboxy-7-deazaguanine synthase 
                EC 4.3.99.4                      choline trimethylamine-lyase 
                EC 4.3.99.5                      nitrosuccinate lyase 
    EC 4.4  [+]      
        EC 4.4.1       []    Carbon-sulfur lyases (only sub-subclass identified to date) 
                EC 4.4.1.1                      cystathionine γ-lyase 
                EC 4.4.1.2                      homocysteine desulfhydrase 
                EC 4.4.1.3                      dimethylpropiothetin dethiomethylase 
                EC 4.4.1.4                      alliin lyase 
                EC 4.4.1.5                      lactoylglutathione lyase 
                EC 4.4.1.6                      S-alkylcysteine lyase. Now included in EC 4.4.1.13, cysteine-S-conjugate β-lyase 
                EC 4.4.1.7                       S-(hydroxyalkyl)glutathione lyase. Now included with EC 2.5.1.18 glutathione transferase 
                EC 4.4.1.8                      cystathionine β-lyase. Now included in EC 4.4.1.13, cysteine-S-conjugate β-lyase 
                EC 4.4.1.9                      L-3-cyanoalanine synthase 
                EC 4.4.1.10                      cysteine lyase 
                EC 4.4.1.11                      methionine γ-lyase 
                EC 4.4.1.12                      sulfoacetaldehyde lyase. Activity due to EC 2.3.3.15, sulfoacetaldehyde acetyltransferase 
                EC 4.4.1.13                      cysteine-S-conjugate β-lyase 
                EC 4.4.1.14                      1-aminocyclopropane-1-carboxylate synthase 
                EC 4.4.1.15                      D-cysteine desulfhydrase 
                EC 4.4.1.16                      selenocysteine lyase 
                EC 4.4.1.17                      holocytochrome-c synthase 
                EC 4.4.1.18                      prenylcysteine lyase. Now EC 1.8.3.5, prenylcysteine oxidase 
                EC 4.4.1.19                      phosphosulfolactate synthase 
                EC 4.4.1.20                      leukotriene-C4 synthase 
                EC 4.4.1.21                      S-ribosylhomocysteine lyase 
                EC 4.4.1.22                      S-(hydroxymethyl)glutathione synthase 
                EC 4.4.1.23                      2-hydroxypropyl-CoM lyase 
                EC 4.4.1.24                      (2R)-sulfolactate sulfo-lyase 
                EC 4.4.1.25                      L-cysteate sulfo-lyase 
                EC 4.4.1.26                      olivetolic acid cyclase 
                EC 4.4.1.27                      carbon disulfide lyase. Now EC 3.13.1.5, carbon disulfide hydrolase 
                EC 4.4.1.28                      L-cysteine desulfidase 
                EC 4.4.1.29                      phycobiliprotein cysteine-84 phycobilin lyase 
                EC 4.4.1.30                      phycobiliprotein β-cysteine-155 phycobilin lyase 
                EC 4.4.1.31                      phycoerythrocyanin α-cysteine-84 phycoviolobilin lyase/isomerase 
                EC 4.4.1.32                      C-phycocyanin α-cysteine-84 phycocyanobilin lyase 
                EC 4.4.1.33                      R-phycocyanin α-cysteine-84 phycourobilin lyase/isomerase 
                EC 4.4.1.34                      isoprene-epoxide—glutathione S-transferase 
                EC 4.4.1.35                      L-cystine β-lyase 
                EC 4.4.1.36                      hercynylcysteine S-oxide lyase 
                EC 4.4.1.37                      pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase 
                EC 4.4.1.38                      isethionate sulfite-lyase 
                EC 4.4.1.39                      C-phycoerythrin α-cysteine-82 phycoerythrobilin lyase 
                EC 4.4.1.40                      C-phycoerythrin β-cysteine-48/59 phycoerythrobilin lyase 
                EC 4.4.1.41                      (2S)-3-sulfopropanediol sulfolyase 
                EC 4.4.1.42                      S-adenosyl-L-methionine lyase 
                EC 4.4.1.43                      canavanine-γ-lyase 
    EC 4.5  [+]      
        EC 4.5.1       []    Carbon-halide lyases (only sub-subclass identified to date) 
                EC 4.5.1.1                      DDT-dehydrochlorinase 
                EC 4.5.1.2                      3-chloro-D-alanine dehydrochlorinase 
                EC 4.5.1.3                      dichloromethane dehalogenase 
                EC 4.5.1.4                      L-2-amino-4-chloropent-4-enoate dehydrochlorinase 
                EC 4.5.1.5                      S-carboxymethylcysteine synthase 
    EC 4.6  [+]      
        EC 4.6.1       []    Phosphorus-oxygen lyases (only sub-subclass identified to date) 
                EC 4.6.1.1                      adenylate cyclase 
                EC 4.6.1.2                      guanylate cyclase 
                EC 4.6.1.3                      3-dehydroquinate synthase. Now EC 4.2.3.4, 3-dehydroquinate synthase 
                EC 4.6.1.4                      chorismate synthase. Now EC 4.2.3.5, chorismate synthase 
                EC 4.6.1.5                      pentalenene synthase. Now EC 4.2.3.7, pentalenene synthase 
                EC 4.6.1.6                      cytidylate cyclase 
                EC 4.6.1.7                      casbene synthase. Now EC 4.2.3.8, casbene synthase 
                EC 4.6.1.8                      (-)-endo-fenchol synthase. Now EC 4.2.3.10, (-)-endo-fenchol synthase 
                EC 4.6.1.9                      sabinene-hydrate synthase. Now EC 4.2.3.11, sabinene-hydrate synthase 
                EC 4.6.1.10                      6-pyruvoyltetrahydropterin synthase. Now EC 4.2.3.12, 6-pyruvoyltetrahydropterin synthase 
                EC 4.6.1.11                      (+)-δ-cadinene synthase. Now EC 4.2.3.13, (+)-δ-cadinene synthase 
                EC 4.6.1.12                      2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 
                EC 4.6.1.13                      phosphatidylinositol diacylglycerol-lyase 
                EC 4.6.1.14                      glycosylphosphatidylinositol diacylglycerol-lyase 
                EC 4.6.1.15                      FAD-AMP lyase (cyclizing) 
                EC 4.6.1.16                      tRNA-intron lyase 
                EC 4.6.1.17                      cyclic pyranopterin monophosphate synthase 
                EC 4.6.1.18                      pancreatic ribonuclease 
                EC 4.6.1.19                      ribonuclease T2 
                EC 4.6.1.20                      ribonuclease U2 
                EC 4.6.1.21                      Enterobacter ribonuclease 
                EC 4.6.1.22                      Bacillus subtilis ribonuclease 
                EC 4.6.1.23                      ribotoxin 
                EC 4.6.1.24                      ribonuclease T1 
                EC 4.6.1.25                      bacteriophage T4 restriction endoribonuclease RegB 
                EC 4.6.1.26                      uridylate cyclase 
    EC 4.7  [+]      
        EC 4.7.1       []    carbon-phosphorus lyases (only sub-subclass identified to date) 
                EC 4.7.1.1                      α-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase 
    EC 4.8  [+]      
        EC 4.8.1       []    Hydro-lyases 
                EC 4.8.1.1                      L-piperazate synthase 
                EC 4.8.1.2                      aliphatic aldoxime dehydratase 
                EC 4.8.1.3                      indoleacetaldoxime dehydratase 
                EC 4.8.1.4                      phenylacetaldoxime dehydratase 
                EC 4.8.1.5                      thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming) 
                EC 4.8.1.6                      N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming) 
                EC 4.8.1.7                      phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase 
                EC 4.8.1.8                      N-(sulfonatooxy)prop-2-enimidothioate sulfolyase 
    EC 4.98  [+]      
        EC 4.98.1       []    Forming coordination complexes 
                EC 4.98.1.1                      protoporphyrin ferrochelatase 
    EC 4.99  [+]      
        EC 4.99.1       []    Sole sub-subclass for lyases that do not belong in the other subclasses 
                EC 4.99.1.1                      protoporphyrin ferrochelatase, now classified as EC 4.98.1.1, protoporphyrin ferrochelatase 
                EC 4.99.1.2                      alkylmercury lyase 
                EC 4.99.1.3                      sirohydrochlorin cobaltochelatase 
                EC 4.99.1.4                      sirohydrochlorin ferrochelatase 
                EC 4.99.1.5                      aliphatic aldoxime dehydratase, now classified as EC 4.8.1.2, aliphatic aldoxime dehydratase 
                EC 4.99.1.6                      indoleacetaldoxime dehydratase, now classified as EC 4.8.1.3, indoleacetaldoxime dehydratase 
                EC 4.99.1.7                      phenylacetaldoxime dehydratase, now classified as EC 4.8.1.4, phenylacetaldoxime dehydratase 
                EC 4.99.1.8                      heme ligase 
                EC 4.99.1.9                      coproporphyrin ferrochelatase 
                EC 4.99.1.10                      magnesium dechelatase 
                EC 4.99.1.11                      sirohydrochlorin nickelchelatase 
                EC 4.99.1.12                      pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase 
EC 5 [+]   
    EC 5.1  [+]      
        EC 5.1.1       []    Acting on amino acids and derivatives 
                EC 5.1.1.1                      alanine racemase 
                EC 5.1.1.2                      methionine racemase 
                EC 5.1.1.3                      glutamate racemase 
                EC 5.1.1.4                      proline racemase 
                EC 5.1.1.5                      lysine racemase 
                EC 5.1.1.6                      threonine racemase 
                EC 5.1.1.7                      diaminopimelate epimerase 
                EC 5.1.1.8                      4-hydroxyproline epimerase 
                EC 5.1.1.9                      arginine racemase 
                EC 5.1.1.10                      amino-acid racemase 
                EC 5.1.1.11                      phenylalanine racemase (ATP-hydrolysing) 
                EC 5.1.1.12                      ornithine racemase 
                EC 5.1.1.13                      aspartate racemase 
                EC 5.1.1.14                      nocardicin A epimerase 
                EC 5.1.1.15                      2-aminohexano-6-lactam racemase 
                EC 5.1.1.16                      protein-serine epimerase 
                EC 5.1.1.17                      isopenicillin-N epimerase 
                EC 5.1.1.18                      serine racemase 
                EC 5.1.1.19                      O-ureido-serine racemase 
                EC 5.1.1.20                      L-Ala-D/L-Glu epimerase 
                EC 5.1.1.21                      isoleucine 2-epimerase 
                EC 5.1.1.22                      4-hydroxyproline betaine 2-epimerase 
                EC 5.1.1.23                      UDP-N-acetyl-α-D-muramoyl-L-alanyl-L-glutamate epimerase 
                EC 5.1.1.24                      histidine racemase 
                EC 5.1.1.25                      N-acetyl-D-glutamate racemase 
        EC 5.1.2       []    Acting on hydroxy acids and derivatives 
                EC 5.1.2.1                      lactate racemase 
                EC 5.1.2.2                      mandelate racemase 
                EC 5.1.2.3                      3-hydroxybutyryl-CoA epimerase 
                EC 5.1.2.4                      acetoin racemase 
                EC 5.1.2.5                      tartrate epimerase 
                EC 5.1.2.6                      isocitrate epimerase 
                EC 5.1.2.7                      tagaturonate epimerase 
        EC 5.1.3       []    Acting on carbohydrates and derivatives 
                EC 5.1.3.1                      ribulose-phosphate 3-epimerase 
                EC 5.1.3.2                      UDP-glucose 4-epimerase 
                EC 5.1.3.3                      aldose 1-epimerase 
                EC 5.1.3.4                      L-ribulose-5-phosphate 4-epimerase 
                EC 5.1.3.5                      UDP-arabinose 4-epimerase 
                EC 5.1.3.6                      UDP-glucuronate 4-epimerase 
                EC 5.1.3.7                      UDP-N-acetylglucosamine 4-epimerase 
                EC 5.1.3.8                      N-acylglucosamine 2-epimerase 
                EC 5.1.3.9                      N-acylglucosamine-6-phosphate 2-epimerase 
                EC 5.1.3.10                      CDP-paratose 2-epimerase 
                EC 5.1.3.11                      cellobiose epimerase 
                EC 5.1.3.12                      UDP-glucuronate 5-epimerase. The enzyme has never been purified and the activity was later shown not to exist. 
                EC 5.1.3.13                      dTDP-4-dehydrorhamnose 3,5-epimerase 
                EC 5.1.3.14                      UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) 
                EC 5.1.3.15                      glucose-6-phosphate 1-epimerase 
                EC 5.1.3.16                      UDP-glucosamine 4-epimerase 
                EC 5.1.3.17                      heparosan-N-sulfate-glucuronate 5-epimerase 
                EC 5.1.3.18                      GDP-mannose 3,5-epimerase 
                EC 5.1.3.19                      chondroitin-glucuronate 5-epimerase 
                EC 5.1.3.20                      ADP-glyceromanno-heptose 6-epimerase 
                EC 5.1.3.21                      maltose epimerase 
                EC 5.1.3.22                      L-ribulose-5-phosphate 3-epimerase 
                EC 5.1.3.23                      UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase 
                EC 5.1.3.24                      N-acetylneuraminate epimerase 
                EC 5.1.3.25                      dTDP-L-rhamnose 4-epimerase 
                EC 5.1.3.26                      N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase 
                EC 5.1.3.27                      dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase 
                EC 5.1.3.28                      UDP-N-acetyl-L-fucosamine synthase 
                EC 5.1.3.29                      L-fucose mutarotase 
                EC 5.1.3.30                      D-psicose 3-epimerase 
                EC 5.1.3.31                      D-tagatose 3-epimerase 
                EC 5.1.3.32                      L-rhamnose mutarotase 
                EC 5.1.3.33                      2-epi-5-epi-valiolone epimerase 
                EC 5.1.3.34                      monoglucosyldiacylglycerol epimerase 
                EC 5.1.3.35                      2-epi-5-epi-valiolone 7-phosphate 2-epimerase 
                EC 5.1.3.36                      heparosan-glucuronate 5-epimerase 
                EC 5.1.3.37                      mannuronan 5-epimerase 
                EC 5.1.3.38                      D-erythrulose 1-phosphate 3-epimerase 
                EC 5.1.3.39                      L-erythrulose 4-phosphate epimerase. The activity has been shown not to take place. 
                EC 5.1.3.40                      D-tagatose 6-phosphate 4-epimerase 
                EC 5.1.3.41                      fructoselysine 3-epimerase 
                EC 5.1.3.42                      D-glucosamine-6-phosphate 4-epimerase 
                EC 5.1.3.43                      sulfoquinovose mutarotase 
                EC 5.1.3.44                      mannose 2-epimerase 
        EC 5.1.99       []    Acting on other compounds 
                EC 5.1.99.1                      methylmalonyl-CoA epimerase 
                EC 5.1.99.2                      16-hydroxysteroid epimerase 
                EC 5.1.99.3                      allantoin racemase 
                EC 5.1.99.4                      α-methylacyl-CoA racemase 
                EC 5.1.99.5                      hydantoin racemase 
                EC 5.1.99.6                      NAD(P)H-hydrate epimerase 
                EC 5.1.99.7                      dihydroneopterin triphosphate 2′-epimerase 
                EC 5.1.99.8                      7,8-dihydroneopterin epimerase 
    EC 5.2  [+]      
        EC 5.2.1       []    cis-trans Isomerases (only sub-subclass identified to date) 
                EC 5.2.1.1                      maleate isomerase 
                EC 5.2.1.2                      maleylacetoacetate isomerase 
                EC 5.2.1.3                      retinal isomerase. Now known to be catalysed by a pathway involving EC 1.1.1.300, NADP-retinol dehydrogenase; EC 2.3.1.135, phosphatidylcholine—retinol O-acyltransferase; EC 3.1.1.64, retinoid isomerohydrolase; and EC 1.1.1.315, 11-cis-retinol dehydrogenase. 
                EC 5.2.1.4                      maleylpyruvate isomerase 
                EC 5.2.1.5                      linoleate isomerase 
                EC 5.2.1.6                      furylfuramide isomerase 
                EC 5.2.1.7                      retinol isomerase. Transferred to EC 3.1.1.64, retinoid isomerohydrolase. 
                EC 5.2.1.8                      peptidylprolyl isomerase 
                EC 5.2.1.9                      farnesol 2-isomerase 
                EC 5.2.1.10                      2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase 
                EC 5.2.1.11                      4-hydroxyphenylacetaldehyde-oxime isomerase. The existence of this enzyme has been called into question by one of the authors of the reference cited 
                EC 5.2.1.12                      ζ-carotene isomerase 
                EC 5.2.1.13                      prolycopene isomerase 
                EC 5.2.1.14                      β-carotene isomerase 
    EC 5.3  [+]      
        EC 5.3.1       []    Interconverting aldoses and ketoses, and related compounds 
                EC 5.3.1.1                      triose-phosphate isomerase 
                EC 5.3.1.2                       erythrose isomerase 
                EC 5.3.1.3                      D-arabinose isomerase 
                EC 5.3.1.4                      L-arabinose isomerase 
                EC 5.3.1.5                      xylose isomerase 
                EC 5.3.1.6                      ribose-5-phosphate isomerase 
                EC 5.3.1.7                      mannose isomerase 
                EC 5.3.1.8                      mannose-6-phosphate isomerase 
                EC 5.3.1.9                      glucose-6-phosphate isomerase 
                EC 5.3.1.10                      glucosamine-6-phosphate isomerase. Now EC 3.5.99.6, glucosamine-6-phosphate deaminase 
                EC 5.3.1.11                       acetylglucosaminephosphate isomerase 
                EC 5.3.1.12                      glucuronate isomerase 
                EC 5.3.1.13                      arabinose-5-phosphate isomerase 
                EC 5.3.1.14                      L-rhamnose isomerase 
                EC 5.3.1.15                      D-lyxose ketol-isomerase 
                EC 5.3.1.16                      1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 
                EC 5.3.1.17                      5-dehydro-4-deoxy-D-glucuronate isomerase 
                EC 5.3.1.18                       glucose isomerase. Reaction is due to EC 5.3.1.9 glucose-6-phosphate isomerase, in the presence of arsenate, or EC 5.3.1.5 xylose isomerase 
                EC 5.3.1.19                      glucosaminephosphate isomerase. Now EC 2.6.1.16, glutamine—fructose-6-phosphate transaminase (isomerizing) 
                EC 5.3.1.20                      ribose isomerase 
                EC 5.3.1.21                      corticosteroid side-chain-isomerase 
                EC 5.3.1.22                      hydroxypyruvate isomerase 
                EC 5.3.1.23                      S-methyl-5-thioribose-1-phosphate isomerase 
                EC 5.3.1.24                      phosphoribosylanthranilate isomerase 
                EC 5.3.1.25                      L-fucose isomerase 
                EC 5.3.1.26                      galactose-6-phosphate isomerase 
                EC 5.3.1.27                      6-phospho-3-hexuloisomerase 
                EC 5.3.1.28                      D-sedoheptulose-7-phosphate isomerase 
                EC 5.3.1.29                      ribose-1,5-bisphosphate isomerase 
                EC 5.3.1.30                      5-deoxy-glucuronate isomerase 
                EC 5.3.1.31                      sulfoquinovose isomerase 
                EC 5.3.1.32                      (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase 
                EC 5.3.1.33                      L-erythrulose-1-phosphate isomerase 
                EC 5.3.1.34                      D-erythrulose 4-phosphate isomerase 
                EC 5.3.1.35                      2-dehydrotetronate isomerase 
                EC 5.3.1.36                      D-apiose isomerase 
                EC 5.3.1.37                      4-deoxy-4-sulfo-D-erythrose isomerase 
        EC 5.3.2       []    Interconverting keto- and enol-groups 
                EC 5.3.2.1                      phenylpyruvate tautomerase 
                EC 5.3.2.2                      oxaloacetate tautomerase 
                EC 5.3.2.3                      TDP-4-oxo-6-deoxy-α-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-α-D-galactopyranose-forming) 
                EC 5.3.2.4                      TDP-4-oxo-6-deoxy-α-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-α-D-glucopyranose-forming) 
                EC 5.3.2.5                      2,3-diketo-5-methylthiopentyl-1-phosphate enolase 
                EC 5.3.2.6                      2-hydroxymuconate tautomerase 
                EC 5.3.2.7                      ascopyrone tautomerase 
                EC 5.3.2.8                      4-oxalomesaconate tautomerase 
        EC 5.3.3       []    Transposing C=C bonds 
                EC 5.3.3.1                      steroid Δ-isomerase 
                EC 5.3.3.2                      isopentenyl-diphosphate Δ-isomerase 
                EC 5.3.3.3                      vinylacetyl-CoA Δ-isomerase 
                EC 5.3.3.4                      muconolactone Δ-isomerase 
                EC 5.3.3.5                      cholestenol Δ-isomerase 
                EC 5.3.3.6                      methylitaconate Δ-isomerase 
                EC 5.3.3.7                      aconitate Δ-isomerase 
                EC 5.3.3.8                      Δ32-enoyl-CoA isomerase 
                EC 5.3.3.9                      prostaglandin-A1 Δ-isomerase 
                EC 5.3.3.10                      5-carboxymethyl-2-hydroxymuconate Δ-isomerase 
                EC 5.3.3.11                      isopiperitenone Δ-isomerase 
                EC 5.3.3.12                      L-dopachrome isomerase 
                EC 5.3.3.13                      polyenoic fatty acid isomerase 
                EC 5.3.3.14                      trans-2-decenoyl-[acyl-carrier protein] isomerase 
                EC 5.3.3.15                      ascopyrone tautomerase. Now EC 5.3.2.7, ascopyrone tautomerase 
                EC 5.3.3.16                      4-oxalomesaconate tautomerase. Now EC 5.3.2.8, 4-oxalomesaconate tautomerase 
                EC 5.3.3.17                      trans-2,3-dihydro-3-hydroxyanthranilate isomerase 
                EC 5.3.3.18                      2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase 
                EC 5.3.3.19                      3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase 
                EC 5.3.3.20                      2-hydroxyisobutanoyl-CoA mutase. Now EC 5.4.99.64, 2-hydroxyisobutanoyl-CoA mutase 
                EC 5.3.3.21                      Δ3,52,4-dienoyl-CoA isomerase 
                EC 5.3.3.22                      lutein isomerase 
                EC 5.3.3.23                      S-methyl-5-thioribulose 1-phosphate isomerase 
                EC 5.3.3.24                      neopinone isomerase 
        EC 5.3.4       []    Transposing S-S bonds 
                EC 5.3.4.1                      protein disulfide-isomerase 
        EC 5.3.99       []    Other intramolecular oxidoreductases 
                EC 5.3.99.1                       hydroperoxide isomerase. Reaction due to combined action of EC 4.2.1.92 (hydroperoxide dehydratase) and EC 5.3.99.6 (allene-oxide cyclase) 
                EC 5.3.99.2                      prostaglandin-D synthase 
                EC 5.3.99.3                      prostaglandin-E synthase 
                EC 5.3.99.4                      prostaglandin-I synthase 
                EC 5.3.99.5                      thromboxane-A synthase 
                EC 5.3.99.6                      allene-oxide cyclase 
                EC 5.3.99.7                      styrene-oxide isomerase 
                EC 5.3.99.8                      capsanthin/capsorubin synthase 
                EC 5.3.99.9                      neoxanthin synthase 
                EC 5.3.99.10                      thiazole tautomerase 
                EC 5.3.99.11                      2-keto-myo-inositol isomerase 
                EC 5.3.99.12                      lachrymatory-factor synthase 
    EC 5.4  [+]      
        EC 5.4.1       []    Transferring acyl groups 
                EC 5.4.1.1                      lysolecithin acylmutase 
                EC 5.4.1.2                      precorrin-8X methylmutase. Now EC 5.4.99.61, precorrin-8X methylmutase 
                EC 5.4.1.3                      2-methylfumaryl-CoA isomerase 
                EC 5.4.1.4                      D-galactarolactone isomerase 
        EC 5.4.2       []      
                EC 5.4.2.1                      phosphoglycerate mutase. Now recognized as two separate enzymes EC 5.4.2.11, phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) and EC 5.4.2.12, phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 
                EC 5.4.2.2                      phosphoglucomutase (α-D-glucose-1,6-bisphosphate-dependent) 
                EC 5.4.2.3                      phosphoacetylglucosamine mutase 
                EC 5.4.2.4                      bisphosphoglycerate mutase 
                EC 5.4.2.5                      phosphoglucomutase (glucose-cofactor) 
                EC 5.4.2.6                      β-phosphoglucomutase 
                EC 5.4.2.7                      phosphopentomutase 
                EC 5.4.2.8                      phosphomannomutase 
                EC 5.4.2.9                      phosphoenolpyruvate mutase 
                EC 5.4.2.10                      phosphoglucosamine mutase 
                EC 5.4.2.11                      phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) 
                EC 5.4.2.12                      phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 
                EC 5.4.2.13                      phosphogalactosamine mutase 
        EC 5.4.3       []    Transferring amino groups 
                EC 5.4.3.1                       ornithine 4,5-aminomutase. This reaction was due to a mixture of EC 5.1.1.12 (ornithine racemase) and EC 5.4.3.5 (D-ornithine 4,5-aminomutase) 
                EC 5.4.3.2                      lysine 2,3-aminomutase 
                EC 5.4.3.3                      lysine 5,6-aminomutase 
                EC 5.4.3.4                      D-lysine 5,6-aminomutase. Now included in EC 5.4.3.3, lysine 5,6-aminomutase 
                EC 5.4.3.5                      D-ornithine 4,5-aminomutase 
                EC 5.4.3.6                      tyrosine 2,3-aminomutase 
                EC 5.4.3.7                      leucine 2,3-aminomutase 
                EC 5.4.3.8                      glutamate-1-semialdehyde 2,1-aminomutase 
                EC 5.4.3.9                      glutamate 2,3-aminomutase 
                EC 5.4.3.10                      phenylalanine aminomutase (L-β-phenylalanine forming) 
                EC 5.4.3.11                      phenylalanine aminomutase (D-β-phenylalanine forming) 
        EC 5.4.4       []    Transferring hydroxy groups 
                EC 5.4.4.1                      (hydroxyamino)benzene mutase 
                EC 5.4.4.2                      isochorismate synthase 
                EC 5.4.4.3                      3-(hydroxyamino)phenol mutase 
                EC 5.4.4.4                      geraniol isomerase 
                EC 5.4.4.5                      9,12-octadecadienoate 8-hydroperoxide 8R-isomerase 
                EC 5.4.4.6                      9,12-octadecadienoate 8-hydroperoxide 8S-isomerase 
                EC 5.4.4.7                      hydroperoxy icosatetraenoate isomerase 
                EC 5.4.4.8                      linalool isomerase 
        EC 5.4.99       []    Transferring other groups 
                EC 5.4.99.1                      methylaspartate mutase 
                EC 5.4.99.2                      methylmalonyl-CoA mutase 
                EC 5.4.99.3                      2-acetolactate mutase 
                EC 5.4.99.4                      2-methyleneglutarate mutase 
                EC 5.4.99.5                      chorismate mutase 
                EC 5.4.99.6                      isochorismate synthase. Now EC 5.4.4.2, isochorismate synthase 
                EC 5.4.99.7                      lanosterol synthase 
                EC 5.4.99.8                      cycloartenol synthase 
                EC 5.4.99.9                      UDP-galactopyranose mutase 
                EC 5.4.99.10                      isomaltulose synthetase. Now included with EC 5.4.99.11, isomaltulose synthase 
                EC 5.4.99.11                      isomaltulose synthase 
                EC 5.4.99.12                      tRNA pseudouridine38-40 synthase 
                EC 5.4.99.13                      isobutyryl-CoA mutase 
                EC 5.4.99.14                      4-carboxymethyl-4-methylbutenolide mutase 
                EC 5.4.99.15                      (1→4)-α-D-glucan 1-α-D-glucosylmutase 
                EC 5.4.99.16                      maltose α-D-glucosyltransferase 
                EC 5.4.99.17                      squalene—hopene cyclase 
                EC 5.4.99.18                      5-(carboxyamino)imidazole ribonucleotide mutase 
                EC 5.4.99.19                      16S rRNA pseudouridine516 synthase 
                EC 5.4.99.20                      23S rRNA pseudouridine2457 synthase 
                EC 5.4.99.21                      23S rRNA pseudouridine2604 synthase 
                EC 5.4.99.22                      23S rRNA pseudouridine2605 synthase 
                EC 5.4.99.23                      23S rRNA pseudouridine1911/1915/1917 synthase 
                EC 5.4.99.24                      23S rRNA pseudouridine955/2504/2580 synthase 
                EC 5.4.99.25                      tRNA pseudouridine55 synthase 
                EC 5.4.99.26                      tRNA pseudouridine65 synthase 
                EC 5.4.99.27                      tRNA pseudouridine13 synthase 
                EC 5.4.99.28                      tRNA pseudouridine32 synthase 
                EC 5.4.99.29                      23S rRNA pseudouridine746 synthase 
                EC 5.4.99.30                      UDP-arabinopyranose mutase 
                EC 5.4.99.31                      thalianol synthase 
                EC 5.4.99.32                      protostadienol synthase 
                EC 5.4.99.33                      cucurbitadienol synthase 
                EC 5.4.99.34                      germanicol synthase 
                EC 5.4.99.35                      taraxerol synthase 
                EC 5.4.99.36                      isomultiflorenol synthase 
                EC 5.4.99.37                      dammaradiene synthase 
                EC 5.4.99.38                      camelliol C synthase 
                EC 5.4.99.39                      β-amyrin synthase 
                EC 5.4.99.40                      α-amyrin synthase 
                EC 5.4.99.41                      lupeol synthase 
                EC 5.4.99.42                      tRNA pseudouridine31 synthase 
                EC 5.4.99.43                      21S rRNA pseudouridine2819 synthase 
                EC 5.4.99.44                      mitochondrial tRNA pseudouridine27/28 synthase 
                EC 5.4.99.45                      tRNA pseudouridine38/39 synthase 
                EC 5.4.99.46                      shionone synthase 
                EC 5.4.99.47                      parkeol synthase 
                EC 5.4.99.48                      achilleol B synthase 
                EC 5.4.99.49                      glutinol synthase 
                EC 5.4.99.50                      friedelin synthase 
                EC 5.4.99.51                      baccharis oxide synthase 
                EC 5.4.99.52                      α-seco-amyrin synthase 
                EC 5.4.99.53                      marneral synthase 
                EC 5.4.99.54                      β-seco-amyrin synthase 
                EC 5.4.99.55                      δ-amyrin synthase 
                EC 5.4.99.56                      tirucalladienol synthase 
                EC 5.4.99.57                      baruol synthase 
                EC 5.4.99.58                      methylornithine synthase 
                EC 5.4.99.59                      dTDP-fucopyranose mutase  
                EC 5.4.99.60                      cobalt-precorrin-8 methylmutase 
                EC 5.4.99.61                      precorrin-8X methylmutase 
                EC 5.4.99.62                      D-ribose pyranase 
                EC 5.4.99.63                      ethylmalonyl-CoA mutase 
                EC 5.4.99.64                      2-hydroxyisobutanoyl-CoA mutase 
                EC 5.4.99.65                      pre-α-onocerin synthase 
                EC 5.4.99.66                      α-onocerin synthase 
                EC 5.4.99.67                      4-amino-4-deoxychorismate mutase 
    EC 5.5  [+]      
        EC 5.5.1       []    Intramolecular lyases (only sub-subclass identified to date) 
                EC 5.5.1.1                      muconate cycloisomerase 
                EC 5.5.1.2                      3-carboxy-cis,cis-muconate cycloisomerase 
                EC 5.5.1.3                      tetrahydroxypteridine cycloisomerase 
                EC 5.5.1.4                      inositol-3-phosphate synthase 
                EC 5.5.1.5                      carboxy-cis,cis-muconate cyclase 
                EC 5.5.1.6                      chalcone isomerase 
                EC 5.5.1.7                      chloromuconate cycloisomerase 
                EC 5.5.1.8                      (+)-bornyl diphosphate synthase 
                EC 5.5.1.9                      cycloeucalenol cycloisomerase 
                EC 5.5.1.10                      α-pinene-oxide decyclase 
                EC 5.5.1.11                      dichloromuconate cycloisomerase 
                EC 5.5.1.12                      copalyl diphosphate synthase 
                EC 5.5.1.13                      ent-copalyl diphosphate synthase 
                EC 5.5.1.14                      syn-copalyl-diphosphate synthase 
                EC 5.5.1.15                      terpentedienyl-diphosphate synthase 
                EC 5.5.1.16                      halimadienyl-diphosphate synthase 
                EC 5.5.1.17                      (S)-β-macrocarpene synthase 
                EC 5.5.1.18                      lycopene ε-cyclase 
                EC 5.5.1.19                      lycopene β-cyclase 
                EC 5.5.1.20                      prosolanapyrone-III cycloisomerase 
                EC 5.5.1.21                      copal-8-ol diphosphate synthase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 4.2.1.133, copal-8-ol diphosphate hydratase 
                EC 5.5.1.22                      (–)-bornyl diphosphate synthase 
                EC 5.5.1.23                      aklanonic acid methyl ester cyclase 
                EC 5.5.1.24                      tocopherol cyclase 
                EC 5.5.1.25                      3,6-anhydro-L-galactonate cycloisomerase 
                EC 5.5.1.26                      nogalonic acid methyl ester cyclase 
                EC 5.5.1.27                      D-galactarolactone cycloisomerase 
                EC 5.5.1.28                      (–)-kolavenyl diphosphate synthase 
                EC 5.5.1.29                      (+)-kolavenyl diphosphate synthase 
                EC 5.5.1.30                      labda-7,13-dienyl diphosphate synthase 
                EC 5.5.1.31                      hapalindole H synthase 
                EC 5.5.1.32                      12-epi-hapalindole U synthase 
                EC 5.5.1.33                      12-epi-fischerindole U synthase 
                EC 5.5.1.34                      (+)-cis,trans-nepetalactol synthase 
                EC 5.5.1.35                      (+)-cis,cis-nepetalactol synthase 
    EC 5.6  [+]      
        EC 5.6.1       []    Enzymes altering polypeptide conformation or assembly 
                EC 5.6.1.1                      microtubule-severing ATPase 
                EC 5.6.1.2                      dynein ATPase 
                EC 5.6.1.3                      plus-end-directed kinesin ATPase 
                EC 5.6.1.4                      minus-end-directed kinesin ATPase 
                EC 5.6.1.5                      proteasome ATPase 
                EC 5.6.1.6                      channel-conductance-controlling ATPase 
                EC 5.6.1.7                      chaperonin ATPase 
                EC 5.6.1.8                      myosin ATPase 
                EC 5.6.1.9                      (R)-2-hydroxyacyl-CoA dehydratase activating ATPase 
        EC 5.6.2       []    Enzymes altering nucleic acid conformation 
                EC 5.6.2.1                      DNA topoisomerase 
                EC 5.6.2.2                      DNA topoisomerase (ATP-hydrolysing) 
                EC 5.6.2.3                      DNA 5′-3′ helicase 
                EC 5.6.2.4                      DNA 3′-5′ helicase 
    EC 5.99  [+]      
        EC 5.99.1       []    Sole sub-subclass for isomerases that do not belong in the other subclasses 
                EC 5.99.1.1                      thiocyanate isomerase 
                EC 5.99.1.2                      DNA topoisomerase. Now EC 5.6.2.1, DNA topoisomerase 
                EC 5.99.1.3                      DNA topoisomerase (ATP-hydrolysing). Now EC 5.6.2.2, DNA topoisomerase (ATP-hydrolysing) 
                EC 5.99.1.4                      2-hydroxychromene-2-carboxylate isomerase 
EC 6 [+]   
    EC 6.1  [+]      
        EC 6.1.1       []    Ligases forming aminoacyl-tRNA and related compounds 
                EC 6.1.1.1                      tyrosine—tRNA ligase 
                EC 6.1.1.2                      tryptophan—tRNA ligase 
                EC 6.1.1.3                      threonine—tRNA ligase 
                EC 6.1.1.4                      leucine—tRNA ligase 
                EC 6.1.1.5                      isoleucine—tRNA ligase 
                EC 6.1.1.6                      lysine—tRNA ligase 
                EC 6.1.1.7                      alanine—tRNA ligase 
                EC 6.1.1.8                       D-alanine-sRNA synthetase 
                EC 6.1.1.9                      valine—tRNA ligase 
                EC 6.1.1.10                      methionine—tRNA ligase 
                EC 6.1.1.11                      serine—tRNA ligase 
                EC 6.1.1.12                      aspartate—tRNA ligase 
                EC 6.1.1.13                      D-alanine—poly(phosphoribitol) ligase 
                EC 6.1.1.14                      glycine—tRNA ligase 
                EC 6.1.1.15                      proline—tRNA ligase 
                EC 6.1.1.16                      cysteine—tRNA ligase 
                EC 6.1.1.17                      glutamate—tRNA ligase 
                EC 6.1.1.18                      glutamine—tRNA ligase 
                EC 6.1.1.19                      arginine—tRNA ligase 
                EC 6.1.1.20                      phenylalanine—tRNA ligase 
                EC 6.1.1.21                      histidine—tRNA ligase 
                EC 6.1.1.22                      asparagine—tRNA ligase 
                EC 6.1.1.23                      aspartate—tRNAAsn ligase 
                EC 6.1.1.24                      glutamate—tRNAGln ligase 
                EC 6.1.1.25                      lysine—tRNAPyl ligase. The tRNAPyl is now known only to be charged with pyrrolysine (cf. EC 6.1.1.26). 
                EC 6.1.1.26                      pyrrolysine—tRNAPyl ligase 
                EC 6.1.1.27                      O-phospho-L-serine—tRNA ligase 
                EC 6.1.1.28                      proline/cysteine—tRNA ligase. Later published work having demonstrated that this was not a genuine enzyme, EC 6.1.1.28 was withdrawn at the public-review stage before being made official. 
        EC 6.1.2       []    acid—alcohol ligases (ester synthases) 
                EC 6.1.2.1                      D-alanine—(R)-lactate ligase 
                EC 6.1.2.2                      nebramycin 5′ synthase 
        EC 6.1.3       []    Cyclo-ligases 
                EC 6.1.3.1                      olefin β-lactone synthetase 
    EC 6.2  [+]      
        EC 6.2.1       []    Acid-thiol ligases 
                EC 6.2.1.1                      acetate—CoA ligase 
                EC 6.2.1.2                      medium-chain acyl-CoA ligase 
                EC 6.2.1.3                      long-chain-fatty-acid—CoA ligase 
                EC 6.2.1.4                      succinate—CoA ligase (GDP-forming) 
                EC 6.2.1.5                      succinate—CoA ligase (ADP-forming) 
                EC 6.2.1.6                      glutarate—CoA ligase 
                EC 6.2.1.7                      cholate—CoA ligase 
                EC 6.2.1.8                      oxalate—CoA ligase 
                EC 6.2.1.9                      malate—CoA ligase 
                EC 6.2.1.10                      carboxylic acid—CoA ligase (GDP-forming) 
                EC 6.2.1.11                      biotin—CoA ligase 
                EC 6.2.1.12                      4-coumarate—CoA ligase 
                EC 6.2.1.13                      acetate—CoA ligase (ADP-forming) 
                EC 6.2.1.14                      6-carboxyhexanoate—CoA ligase 
                EC 6.2.1.15                      arachidonate—CoA ligase 
                EC 6.2.1.16                      acetoacetate—CoA ligase 
                EC 6.2.1.17                      propionate—CoA ligase 
                EC 6.2.1.18                      citrate—CoA ligase 
                EC 6.2.1.19                      long-chain-fatty-acid—protein ligase 
                EC 6.2.1.20                      long-chain-fatty-acid—[acyl-carrier-protein] ligase 
                EC 6.2.1.21                       phenylacetate—CoA ligase. Activity covered by EC 6.2.1.30, phenylacetate—CoA ligase 
                EC 6.2.1.22                      [citrate (pro-3S)-lyase] ligase 
                EC 6.2.1.23                      dicarboxylate—CoA ligase 
                EC 6.2.1.24                      phytanate—CoA ligase 
                EC 6.2.1.25                      benzoate—CoA ligase 
                EC 6.2.1.26                      o-succinylbenzoate—CoA ligase 
                EC 6.2.1.27                      4-hydroxybenzoate—CoA ligase 
                EC 6.2.1.28                      3α,7α-dihydroxy-5β-cholestanate—CoA ligase 
                EC 6.2.1.29                       3α,7α,12α-trihydroxy-5β-cholestanate—CoA ligase. The enzyme is identical to EC 6.2.1.7, cholate—CoA ligase 
                EC 6.2.1.30                      phenylacetate—CoA ligase 
                EC 6.2.1.31                      2-furoate—CoA ligase 
                EC 6.2.1.32                      anthranilate—CoA ligase 
                EC 6.2.1.33                      4-chlorobenzoate—CoA ligase 
                EC 6.2.1.34                      trans-feruloyl-CoA synthase 
                EC 6.2.1.35                      acetate—[acyl-carrier protein] ligase 
                EC 6.2.1.36                      3-hydroxypropionyl-CoA synthase 
                EC 6.2.1.37                      3-hydroxybenzoate—CoA ligase 
                EC 6.2.1.38                      (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase 
                EC 6.2.1.39                      [butirosin acyl-carrier protein]—L-glutamate ligase 
                EC 6.2.1.40                      4-hydroxybutyrate—CoA ligase (AMP-forming) 
                EC 6.2.1.41                      3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate—CoA ligase 
                EC 6.2.1.42                      3-oxocholest-4-en-26-oate—CoA ligase 
                EC 6.2.1.43                      2-hydroxy-7-methoxy-5-methyl-1-naphthoate—CoA ligase 
                EC 6.2.1.44                      3-(methylthio)propionyl—CoA ligase 
                EC 6.2.1.45                      E1 ubiquitin-activating enzyme 
                EC 6.2.1.46                      L-allo-isoleucine—holo-[CmaA peptidyl-carrier protein] ligase 
                EC 6.2.1.47                      medium-chain-fatty-acid—[acyl-carrier-protein] ligase 
                EC 6.2.1.48                      carnitine—CoA ligase 
                EC 6.2.1.49                      long-chain fatty acid adenylyltransferase FadD28 
                EC 6.2.1.50                      4-hydroxybenzoate adenylyltransferase FadD22 
                EC 6.2.1.51                      4-hydroxyphenylalkanoate adenylyltransferase FadD29 
                EC 6.2.1.52                      L-firefly luciferin—CoA ligase 
                EC 6.2.1.53                      L-proline—[L-prolyl-carrier protein] ligase 
                EC 6.2.1.54                      D-alanine—[D-alanyl-carrier protein] ligase 
                EC 6.2.1.55                      E1 SAMP-activating enzyme 
                EC 6.2.1.56                      4-hydroxybutyrate—CoA ligase (ADP-forming) 
                EC 6.2.1.57                      long-chain fatty acid adenylase/transferase FadD23 
                EC 6.2.1.58                      isophthalate—CoA ligase 
                EC 6.2.1.59                      long-chain fatty acid adenylase/transferase FadD26 
                EC 6.2.1.60                      marinolic acid—CoA ligase 
                EC 6.2.1.61                      salicylate—[aryl-carrier protein] ligase 
                EC 6.2.1.62                      3,4-dihydroxybenzoate—[aryl-carrier protein] ligase 
                EC 6.2.1.63                      L-arginine—[L-arginyl-carrier protein] ligase 
                EC 6.2.1.64                      E1 NEDD8-activating enzyme 
                EC 6.2.1.65                      salicylate—CoA ligase 
                EC 6.2.1.66                      glyine—[glycyl-carrier protein] ligase 
                EC 6.2.1.67                      L-alanine—[L-alanyl-carrier protein] ligase 
                EC 6.2.1.68                      L-glutamate—[L-glutamyl-carrier protein] ligase 
                EC 6.2.1.69                      L-cysteine—[L-cysteinyl-carrier protein] ligase 
                EC 6.2.1.70                      L-threonine—[L-threonyl-carrier protein] ligase 
                EC 6.2.1.71                      2,3-dihydroxybenzoate—[aryl-carrier protein] ligase 
                EC 6.2.1.72                      L-serine—[L-seryl-carrier protein] ligase 
                EC 6.2.1.73                      L-tryptophan—[L-tryptophyl-carrier protein] ligase 
                EC 6.2.1.74                      3-amino-5-hydroxybenzoate—[acyl-carrier protein] ligase 
                EC 6.2.1.75                      indoleacetate—CoA ligase 
                EC 6.2.1.76                      malonate—CoA ligase 
        EC 6.2.2       []    Amide---thiol ligases 
                EC 6.2.2.1                      thioglycine synthase 
                EC 6.2.2.2                      oxazoline synthase 
                EC 6.2.2.3                      thiazoline synthase 
    EC 6.3  [+]      
        EC 6.3.1       []    Acid—ammonia (or amine) ligases (amide synthases) 
                EC 6.3.1.1                      aspartate—ammonia ligase 
                EC 6.3.1.2                      glutamine synthetase 
                EC 6.3.1.3                      phosphoribosyl-glycinamide synthetase. Now EC 6.3.4.13, phosphoribosylamine—glycine ligase 
                EC 6.3.1.4                      aspartate—ammonia ligase (ADP-forming) 
                EC 6.3.1.5                      NAD+ synthase 
                EC 6.3.1.6                      glutamate—ethylamine ligase 
                EC 6.3.1.7                      4-methyleneglutamate—ammonia ligase 
                EC 6.3.1.8                      glutathionylspermidine synthase 
                EC 6.3.1.9                      trypanothione synthase 
                EC 6.3.1.10                      adenosylcobinamide-phosphate synthase 
                EC 6.3.1.11                      glutamate—putrescine ligase 
                EC 6.3.1.12                      D-aspartate ligase 
                EC 6.3.1.13                      L-cysteine:1D-myo-inositol 2-amino-2-deoxy-α-D-glucopyranoside ligase 
                EC 6.3.1.14                      diphthine—ammonia ligase 
                EC 6.3.1.15                      8-demethylnovobiocic acid synthase 
                EC 6.3.1.16                      carbapenam-3-carboxylate synthetase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 6.3.3.6, carbapenam-3-carboxylate synthase 
                EC 6.3.1.17                      β-citrylglutamate synthase 
                EC 6.3.1.18                      γ-glutamylanilide synthase 
                EC 6.3.1.19                      prokaryotic ubiquitin-like protein ligase 
                EC 6.3.1.20                      lipoate—protein ligase 
                EC 6.3.1.21                      phosphoribosylglycinamide formyltransferase 2 
        EC 6.3.2       []    Acid—amino-acid ligases (peptide synthases) 
                EC 6.3.2.1                      pantoate—β-alanine ligase (AMP-forming) 
                EC 6.3.2.2                      glutamate—cysteine ligase 
                EC 6.3.2.3                      glutathione synthase 
                EC 6.3.2.4                      D-alanine—D-alanine ligase 
                EC 6.3.2.5                      phosphopantothenate—cysteine ligase (CTP) 
                EC 6.3.2.6                      phosphoribosylaminoimidazolesuccinocarboxamide synthase 
                EC 6.3.2.7                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—L-lysine ligase 
                EC 6.3.2.8                      UDP-N-acetylmuramate—L-alanine ligase 
                EC 6.3.2.9                      UDP-N-acetylmuramoyl-L-alanine—D-glutamate ligase 
                EC 6.3.2.10                      UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase 
                EC 6.3.2.11                      carnosine synthase 
                EC 6.3.2.12                      dihydrofolate synthase 
                EC 6.3.2.13                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase 
                EC 6.3.2.14                      enterobactin synthase 
                EC 6.3.2.15                       UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase. The activity observed is due to EC 6.3.2.10, UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase 
                EC 6.3.2.16                      D-alanine—alanyl-poly(glycerolphosphate) ligase 
                EC 6.3.2.17                      tetrahydrofolate synthase 
                EC 6.3.2.18                      γ-glutamylhistamine synthase 
                EC 6.3.2.19                      ubiquitin—protein ligase. The ubiquitinylation process is now known to be performed by several enzymes in sequence, starting with EC 6.2.1.45 (ubiquitin-activating enzyme E1) and followed by several transfer reactions, including those of EC 2.3.2.23 (E2 ubiquitin-conjugating enzyme) and EC 2.3.2.27 (RING-type E3 ubiquitin transferase) 
                EC 6.3.2.20                      indoleacetate—lysine synthetase 
                EC 6.3.2.21                      ubiquitin—calmodulin ligase. The reaction is performed by the sequential action of EC 6.2.1.45 (ubiquitin-activating enzyme E1), several ubiquitin transferases and finally by EC 2.3.2.27 [ubiquitin transferase RING E3 (calmodulin-selective)] 
                EC 6.3.2.22                      diphthine—ammonia ligase. Now EC 6.3.1.14, diphthine—ammonia ligase. 
                EC 6.3.2.23                      homoglutathione synthase 
                EC 6.3.2.24                      tyrosine—arginine ligase 
                EC 6.3.2.25                      tubulin—tyrosine ligase 
                EC 6.3.2.26                      N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase 
                EC 6.3.2.27                      The activity is covered by two independent enzymes, EC 6.3.2.38 N2-citryl-N6-acetyl-N6-hydroxylysine synthase, and EC 6.3.2.39, aerobactin synthase 
                EC 6.3.2.28                      L-amino-acid α-ligase. Now EC 6.3.2.49, L-alanine-L-anticapsin ligase 
                EC 6.3.2.29                      cyanophycin synthase (L-aspartate-adding) 
                EC 6.3.2.30                      cyanophycin synthase (L-arginine-adding) 
                EC 6.3.2.31                      coenzyme F420-0:L-glutamate ligase 
                EC 6.3.2.32                      coenzyme γ-F420-2:α-L-glutamate ligase 
                EC 6.3.2.33                      tetrahydrosarcinapterin synthase 
                EC 6.3.2.34                      coenzyme F420-1:γ-L-glutamate ligase 
                EC 6.3.2.35                      D-alanine—D-serine ligase 
                EC 6.3.2.36                      4-phosphopantoate—β-alanine ligase 
                EC 6.3.2.37                      UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—D-lysine ligase 
                EC 6.3.2.38                      N2-citryl-N6-acetyl-N6-hydroxylysine synthase 
                EC 6.3.2.39                      aerobactin synthase 
                EC 6.3.2.40                      cyclopeptine synthase 
                EC 6.3.2.41                      N-acetylaspartylglutamate synthase 
                EC 6.3.2.42                      N-acetylaspartylglutamylglutamate synthase 
                EC 6.3.2.43                      [amino-group carrier protein]—L-2-aminoadipate ligase 
                EC 6.3.2.44                      pantoate—β-alanine ligase (ADP-forming) 
                EC 6.3.2.45                      UDP-N-acetylmuramate—L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioate ligase 
                EC 6.3.2.46                      fumarate—(S)-2,3-diaminopropanoate ligase 
                EC 6.3.2.47                      dapdiamide synthase 
                EC 6.3.2.48                      L-arginine-specific L-amino acid ligase 
                EC 6.3.2.49                      L-alanine—L-anticapsin ligase 
                EC 6.3.2.50                      tenuazonic acid synthetase 
                EC 6.3.2.51                      phosphopantothenate—cysteine ligase (ATP) 
                EC 6.3.2.52                      jasmonoyl—L-amino acid ligase 
                EC 6.3.2.53                      UDP-N-acetylmuramoyl-L-alanine—L-glutamate ligase 
                EC 6.3.2.54                      L-2,3-diaminopropanoate—citrate ligase 
                EC 6.3.2.55                      2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase 
                EC 6.3.2.56                      staphyloferrin B synthase 
                EC 6.3.2.57                      staphyloferrin A synthase 
                EC 6.3.2.58                      D-ornithine—citrate ligase 
                EC 6.3.2.59                      3-methyl-D-ornithine—L-lysine ligase 
                EC 6.3.2.60                      glutamate—[amino group carrier protein] ligase 
                EC 6.3.2.61                      tubulin-glutamate ligase 
                EC 6.3.2.62                      β-tubulin-glutamate ligase 
        EC 6.3.3       []    Cyclo-ligases 
                EC 6.3.3.1                      phosphoribosylformylglycinamidine cyclo-ligase 
                EC 6.3.3.2                      5-formyltetrahydrofolate cyclo-ligase 
                EC 6.3.3.3                      dethiobiotin synthase 
                EC 6.3.3.4                      (carboxyethyl)arginine β-lactam-synthase 
                EC 6.3.3.5                      O-ureido-D-serine cyclo-ligase 
                EC 6.3.3.6                      carbapenam-3-carboxylate synthase 
                EC 6.3.3.7                      Ni-sirohydrochlorin a,c-diamide reductive cyclase 
        EC 6.3.4       []    Other carbon-nitrogen ligases 
                EC 6.3.4.1                      GMP synthase. Now included in EC 6.3.5.2, GMP synthase (glutamine-hydrolysing) 
                EC 6.3.4.2                      CTP synthase (glutamine hydrolysing) 
                EC 6.3.4.3                      formate—tetrahydrofolate ligase 
                EC 6.3.4.4                      adenylosuccinate synthase 
                EC 6.3.4.5                      argininosuccinate synthase 
                EC 6.3.4.6                      urea carboxylase 
                EC 6.3.4.7                      ribose-5-phosphate—ammonia ligase 
                EC 6.3.4.8                      imidazoleacetate—phosphoribosyldiphosphate ligase 
                EC 6.3.4.9                      biotin—[methylmalonyl-CoA-carboxytransferase] ligase 
                EC 6.3.4.10                      biotin—[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase 
                EC 6.3.4.11                      biotin—[methylcrotonoyl-CoA-carboxylase] ligase 
                EC 6.3.4.12                      glutamate—methylamine ligase 
                EC 6.3.4.13                      phosphoribosylamine—glycine ligase 
                EC 6.3.4.14                      biotin carboxylase 
                EC 6.3.4.15                      biotin—[biotin carboxyl-carrier protein] ligase 
                EC 6.3.4.16                      carbamoyl-phosphate synthase (ammonia) 
                EC 6.3.4.17                      formate—dihydrofolate ligase 
                EC 6.3.4.18                      5-(carboxyamino)imidazole ribonucleotide synthase 
                EC 6.3.4.19                      tRNAIle-lysidine synthase 
                EC 6.3.4.20                      7-cyano-7-deazaguanine synthase 
                EC 6.3.4.21                      nicotinate phosphoribosyltransferase 
                EC 6.3.4.22                      tRNAIle2-agmatinylcytidine synthase  
                EC 6.3.4.23                      formate—phosphoribosylaminoimidazolecarboxamide ligase 
                EC 6.3.4.24                      tyramine—L-glutamate ligase 
                EC 6.3.4.25                      2-amino-2′-deoxyadenylo-succinate synthase 
        EC 6.3.5       []    Carbon-nitrogen ligases with glutamine as amido-N-donor 
                EC 6.3.5.1                      NAD+ synthase (glutamine-hydrolysing) 
                EC 6.3.5.2                      GMP synthase (glutamine-hydrolysing) 
                EC 6.3.5.3                      phosphoribosylformylglycinamidine synthase 
                EC 6.3.5.4                      asparagine synthase (glutamine-hydrolysing) 
                EC 6.3.5.5                      carbamoyl-phosphate synthase (glutamine-hydrolysing) 
                EC 6.3.5.6                      asparaginyl-tRNA synthase (glutamine-hydrolysing) 
                EC 6.3.5.7                      glutaminyl-tRNA synthase (glutamine-hydrolysing) 
                EC 6.3.5.8                      aminodeoxychorismate synthase. Now EC 2.6.1.85, aminodeoxychorismate synthase. As ATP is not hydrolysed during the reaction, the classification of the enzyme as a ligase was incorrect 
                EC 6.3.5.9                      hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) 
                EC 6.3.5.10                      adenosylcobyric acid synthase (glutamine-hydrolysing) 
                EC 6.3.5.11                      cobyrinate a,c-diamide synthase 
                EC 6.3.5.12                      Ni-sirohydrochlorin a,c-diamide synthase 
                EC 6.3.5.13                      lipid II isoglutaminyl synthase (glutamine-hydrolysing) 
    EC 6.4  [+]      
        EC 6.4.1       []    Ligases that form carbon-carbon bonds (only sub-subclass identified to date) 
                EC 6.4.1.1                      pyruvate carboxylase 
                EC 6.4.1.2                      acetyl-CoA carboxylase 
                EC 6.4.1.3                      propionyl-CoA carboxylase 
                EC 6.4.1.4                      methylcrotonoyl-CoA carboxylase 
                EC 6.4.1.5                      geranoyl-CoA carboxylase 
                EC 6.4.1.6                      acetone carboxylase 
                EC 6.4.1.7                      2-oxoglutarate carboxylase 
                EC 6.4.1.8                      acetophenone carboxylase 
                EC 6.4.1.9                      coenzyme F430 synthetase 
    EC 6.5  [+]      
        EC 6.5.1       []    Ligases that form phosphoric-ester bonds (only sub-subclass identified to date) 
                EC 6.5.1.1                      DNA ligase (ATP) 
                EC 6.5.1.2                      DNA ligase (NAD+) 
                EC 6.5.1.3                      RNA ligase (ATP) 
                EC 6.5.1.4                      RNA 3′-terminal-phosphate cyclase (ATP) 
                EC 6.5.1.5                      RNA 3′-terminal-phosphate cyclase (GTP) 
                EC 6.5.1.6                      DNA ligase (ATP or NAD+) 
                EC 6.5.1.7                      DNA ligase (ATP, ADP or GTP) 
                EC 6.5.1.8                      3′-phosphate/5′-hydroxy nucleic acid ligase 
                EC 6.5.1.9                      cyclic 2,3-diphosphoglycerate synthase 
    EC 6.6  [+]      
        EC 6.6.1       []    Forming coordination complexes 
                EC 6.6.1.1                      magnesium chelatase 
                EC 6.6.1.2                      cobaltochelatase 
    EC 6.7  [+]      
        EC 6.7.1       []    Forming diazo bonds 
                EC 6.7.1.1                      3-amino-2-hydroxy-4-methoxybenzoate diazotase 
                EC 6.7.1.2                      3-aminoavenalumate diazotase 
EC 7 [+]   
    EC 7.1  [+]      
        EC 7.1.1       []    Linked to oxidoreductase reactions 
                EC 7.1.1.1                      proton-translocating NAD(P)+ transhydrogenase 
                EC 7.1.1.2                      NADH:ubiquinone reductase (H+-translocating) 
                EC 7.1.1.3                      ubiquinol oxidase (H+-transporting) 
                EC 7.1.1.4                      caldariellaquinol oxidase (H+-transporting) 
                EC 7.1.1.5                      menaquinol oxidase (H+-transporting) 
                EC 7.1.1.6                      plastoquinol—plastocyanin reductase 
                EC 7.1.1.7                      quinol oxidase (electrogenic, proton-motive force generating) 
                EC 7.1.1.8                      quinol—cytochrome-c reductase 
                EC 7.1.1.9                      cytochrome-c oxidase 
                EC 7.1.1.10                      ferredoxin—quinone oxidoreductase (H+-translocating) 
                EC 7.1.1.11                      ferredoxin—NAD+ oxidoreductase (H+-transporting) 
                EC 7.1.1.12                      succinate dehydrogenase (electrogenic, proton-motive force generating) 
        EC 7.1.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.1.2.1                      P-type H+-exporting transporter 
                EC 7.1.2.2                      H+-transporting two-sector ATPase 
        EC 7.1.3       []    Linked to the hydrolysis of diphosphate 
                EC 7.1.3.1                      H+-exporting diphosphatase 
                EC 7.1.3.2                      Na+-exporting diphosphatase. Now EC 7.2.3.1, Na+-exporting diphosphatase 
    EC 7.2  [+]      
        EC 7.2.1       []    Linked to oxidoreductase reactions 
                EC 7.2.1.1                      NADH:ubiquinone reductase (Na+-transporting) 
                EC 7.2.1.2                      ferredoxin—NAD+ oxidoreductase (Na+-transporting) 
                EC 7.2.1.3                      ascorbate ferrireductase (transmembrane) 
        EC 7.2.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.2.2.1                      Na+-transporting two-sector ATPase 
                EC 7.2.2.2                      ABC-type Cd2+ transporter 
                EC 7.2.2.3                      P-type Na+ transporter 
                EC 7.2.2.4                      ABC-type Na+ transporter 
                EC 7.2.2.5                      ABC-type Mn2+ transporter 
                EC 7.2.2.6                      P-type K+ transporter 
                EC 7.2.2.7                      ABC-type Fe3+ transporter 
                EC 7.2.2.8                      P-type Cu+ transporter 
                EC 7.2.2.9                      P-type Cu2+ transporter 
                EC 7.2.2.10                      P-type Ca2+ transporter 
                EC 7.2.2.11                      ABC-type Ni2+ transporter 
                EC 7.2.2.12                      P-type Zn2+ transporter 
                EC 7.2.2.13                      Na+/K+-exchanging ATPase 
                EC 7.2.2.14                      P-type Mg2+ transporter 
                EC 7.2.2.15                      P-type Ag+ transporter 
                EC 7.2.2.16                      ABC-type ferric hydroxamate transporter 
                EC 7.2.2.17                      ABC-type ferric enterobactin transporter 
                EC 7.2.2.18                      ABC-type ferric citrate transporter 
                EC 7.2.2.19                      H+/K+-exchanging ATPase 
                EC 7.2.2.20                      ABC-type Zn2+ transporter 
                EC 7.2.2.21                      Cd2+-exporting ATPase 
                EC 7.2.2.22                      P-type Mn2+ transporter 
        EC 7.2.4       []    Linked to decarboxylation 
                EC 7.2.4.1                      carboxybiotin decarboxylase 
                EC 7.2.4.2                      oxaloacetate decarboxylase (Na+ extruding) 
                EC 7.2.4.3                      (S)-methylmalonyl-CoA decarboxylase (sodium-transporting) 
                EC 7.2.4.4                      biotin-dependent malonate decarboxylase 
                EC 7.2.4.5                      glutaconyl-CoA decarboxylase 
    EC 7.3  [+]      
        EC 7.3.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.3.2.1                      ABC-type phosphate transporter 
                EC 7.3.2.2                      ABC-type phosphonate transporter 
                EC 7.3.2.3                      ABC-type sulfate transporter 
                EC 7.3.2.4                      ABC-type nitrate transporter 
                EC 7.3.2.5                      ABC-type molybdate transporter 
                EC 7.3.2.6                      ABC-type tungstate transporter 
                EC 7.3.2.7                      arsenite-transporting ATPase 
    EC 7.4  [+]      
        EC 7.4.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.4.2.1                      ABC-type polar-amino-acid transporter 
                EC 7.4.2.2                      ABC-type nonpolar-amino-acid transporter 
                EC 7.4.2.3                      mitochondrial protein-transporting ATPase 
                EC 7.4.2.4                      chloroplast protein-transporting ATPase 
                EC 7.4.2.5                      bacterial ABC-type protein transporter 
                EC 7.4.2.6                      ABC-type oligopeptide transporter 
                EC 7.4.2.7                      ABC-type α-factor-pheromone transporter 
                EC 7.4.2.8                      protein-secreting ATPase 
                EC 7.4.2.9                      ABC-type dipeptide transporter 
                EC 7.4.2.10                      ABC-type glutathione transporter 
                EC 7.4.2.11                      ABC-type methionine transporter 
                EC 7.4.2.12                      ABC-type cystine transporter 
                EC 7.4.2.13                      ABC-type tyrosine transporter 
                EC 7.4.2.14                      ABC-type antigen peptide transporter 
    EC 7.5  [+]      
        EC 7.5.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.5.2.1                      ABC-type maltose transporter 
                EC 7.5.2.2                      ABC-type oligosaccharide transporter 
                EC 7.5.2.3                      ABC-type β-glucan transporter 
                EC 7.5.2.4                      ABC-type teichoic-acid transporter 
                EC 7.5.2.5                      ABC-type lipopolysaccharide transporter 
                EC 7.5.2.6                      ABC-type lipid A-core oligosaccharide transporter 
                EC 7.5.2.7                      ABC-type D-ribose transporter 
                EC 7.5.2.8                      ABC-type D-allose transporter 
                EC 7.5.2.9                      ABC-type D-galactofuranose transporter 
                EC 7.5.2.10                      ABC-type D-xylose transporter 
                EC 7.5.2.11                      ABC-type D-galactose transporter 
                EC 7.5.2.12                      ABC-type L-arabinose transporter 
                EC 7.5.2.13                      ABC-type D-xylose/L-arabinose transporter 
                EC 7.5.2.14                      ABC-type homopolymeric O-antigen exporter 
    EC 7.6  [+]      
        EC 7.6.2       []    Linked to the hydrolysis of a nucleoside triphosphate 
                EC 7.6.2.1                      P-type phospholipid transporter 
                EC 7.6.2.2                      ABC-type xenobiotic transporter 
                EC 7.6.2.3                      ABC-type glutathione-S-conjugate transporter 
                EC 7.6.2.4                      ABC-type fatty-acyl-CoA transporter 
                EC 7.6.2.5                      ABC-type heme transporter 
                EC 7.6.2.6                      ABC-type guanine transporter 
                EC 7.6.2.7                      ABC-type taurine transporter 
                EC 7.6.2.8                      ABC-type vitamin B12 transporter 
                EC 7.6.2.9                      ABC-type quaternary amine transporter 
                EC 7.6.2.10                      ABC-type glycerol 3-phosphate transporter 
                EC 7.6.2.11                      ABC-type polyamine transporter 
                EC 7.6.2.12                      ABC-type capsular-polysaccharide transporter 
                EC 7.6.2.13                      ABC-type autoinducer-2 transporter 
                EC 7.6.2.14                      ABC-type aliphatic sulfonate transporter 
                EC 7.6.2.15                      ABC-type thiamine transporter 
                EC 7.6.2.16                      ABC-type putrescine transporter 


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